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Topic Review
Pathophysiology of Acute Myeloid Leukemia
Acute myeloid leukemia is a cancerous condition that affects hemopoietic stem cells or progenitors and is defined by the stopping of myeloid lineage development and abnormal proliferation.
  • 1.3K
  • 30 Mar 2023
Topic Review
List of Vaccine Topics
This is a list of vaccine-related topics. A vaccine is a biological preparation that improves immunity to a particular disease. A vaccine typically contains an agent that resembles a disease-causing microorganism, and is often made from weakened or killed forms of the microbe or its toxins. The agent stimulates the body's immune system to recognize the agent as foreign, destroy it, and "remember" it, so that the immune system can more easily recognize and destroy any of these microorganisms that it later encounters.
  • 1.3K
  • 04 Nov 2022
Topic Review
Heme Metabolism
Mitochondria are essential organelles of mammalian cells, often emphasized for their function in energy production, iron metabolism and apoptosis as well as heme synthesis. The heme is an iron-loaded porphyrin behaving as a prosthetic group by its interactions with a wide variety of proteins. These complexes are termed hemoproteins and are usually vital to the whole cell comportment, such as the proteins hemoglobin, myoglobin or cytochromes, but also enzymes such as catalase and peroxidases. The building block of porphyrins is the 5-aminolevulinic acid, whose exogenous administration is able to stimulate the entire heme biosynthesis route. In neoplastic cells, this methodology repeatedly demonstrated an accumulation of the ultimate heme precursor, the fluorescent protoporphyrin IX photosensitizer, rather than in healthy tissues.
  • 1.3K
  • 27 Jul 2022
Topic Review
Potato Affected by Heat and Drought Stress
Potato crop species are highly prone to different abiotic (high-temperature stress, drought, salinity, and mineral stress).
  • 1.3K
  • 01 Nov 2022
Topic Review
Plant Species and Expression Systems on Vaccines Production
Use of plant cells as vaccine production hosts is appropriate for the expression of complex antigens in a cost-efficient manner. Recombinant proteins can be produced using various expression systems, each of which has its own benefits and disadvantages pertaining to the yield, time required for expression and the costs incurred in this process.
  • 1.3K
  • 18 Jan 2023
Topic Review
Epstein–Barr Virus Latency
Epstein–Barr virus (EBV) is one of eight known herpesviruses with the potential to infect humans. EBV latency, and more particularly the proteins expressed during this phase of the viral cycle, is heavily implicated in EBV-mediated oncogenesis.
  • 1.3K
  • 30 Nov 2022
Topic Review
Yukon Wolf
The North American wolf Canis lupus pambasileus is a subspecies of gray wolf that is called the Yukon wolf in Canada and the Alaskan Interior wolf in the United States. It is native to the Alaska Interior and Yukon, save for the tundra region of the Arctic Coast.
  • 1.3K
  • 08 Oct 2022
Topic Review
Egyptian Honeybee
The Egyptian honeybee (Apis mellifera lamarckii) is one of the honeybee subspecies known for centuries since the ancient Egypt civilization. The subspecies of the Egyptian honeybee is distinguished by certain traits of appearance and behavior that were well-adapted to the environment and unique in a way that it is resistant to bee diseases, such as the Varroa disease. The subspecies is different than those found in Europe and is native to southern Egypt.
  • 1.3K
  • 21 Oct 2022
Topic Review
Postbiotics
Postbiotics include any substance released by or produced through the metabolic activity of the microorganism, which exerts a beneficial effect on the host, directly or indirectly. As postbiotics do not contain live microorganisms, the risks associated with their intake are minimized. Postbiotics play a vital role in the maturation of the immune system, affect barrier tightness and the intestinal ecosystem, and indirectly shape the structure of the microbiota. Postbiotics display pleiotropic effects, including their immunomodulatory, anti-inflammatory, antioxidant, and anti-cancer properties. As such, postbiotics may be useful in treating or preventing many disease entities, including those for which effective causal therapy has not yet been found.
  • 1.3K
  • 05 Nov 2020
Topic Review
Probiotic Lactobacillus in Anti-Ageing
Probiotics are defined as live microorganisms that confer a health benefit on the host when administered adequately. The most common probiotic strains are associated with the genera Lactobacillus and Bifidobacterium. Recent advancements have witnessed significant achievements in using Lactobacillus during animal studies in ageing models.
  • 1.3K
  • 22 Dec 2021
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