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Topic Review
Google+
Google Plus (stylized as Google+) is an Internet-based social network that is owned and operated by Google. The service, Google's fourth foray into social networking, experienced strong growth in its initial years, although usage statistics have varied, depending on how the service is defined. Three Google executives have overseen the service, which has undergone substantial changes leading to a redesign in November 2015. On October 8, 2018, Google announced that it was shutting down Google+ for consumers, citing low user engagement and a software error, first reported by The Wall Street Journal , that potentially exposed the data of hundreds of thousands of users. Google indicated that Google+ would operate until August 2019, allowing users to download and migrate their information.
  • 6.1K
  • 12 Oct 2022
Topic Review
Physical Information
Physical information is a form of information. In physics, it refers to the information of a physical system. Physical information is an important concept used in a number of fields of study in physics. For example, in quantum mechanics, the form of physical information known as quantum information is used in many descriptions of quantum phenomena, such as quantum observation, quantum entanglement and the causal relationship between quantum objects that carry out either or both close and long-range interactions with one another. In a general sense, information is that which resolves uncertainty, which is due to the fact that it describes the details of that which is associated with the uncertainty. The description itself is, however, divorced from any type of language. When clarifying the subject of information, care should be taken to distinguish between the following specific cases: As the above usages are all conceptually distinct from each other, overloading the word "information" (by itself) to denote (or connote) several of these concepts simultaneously can lead to confusion. Accordingly, this article uses more detailed phrases, such as those shown in bold above, whenever the intended meaning is not made clear by the context.
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  • 09 Oct 2022
Topic Review
Republicanism
Republicanism is a political ideology centred on citizenship in a state organized as a republic under which the people hold popular sovereignty. Many countries are "republics" in the sense that they are not monarchies. The word "republic" derives from the Latin noun-phrase res publica, which referred to the system of government that emerged in the 6th century BC following the expulsion of the kings from Rome by Lucius Junius Brutus and Collatinus. This form of government in the Roman state collapsed in the latter part of the 1st century BCE, giving way to what was a monarchy in form, if not in name. Republics re-occurred subsequently, with, for example, Renaissance Florence or early modern Britain. The concept of a republic became a powerful force in Britain's North American colonies, where it contributed to the American Revolution. In Europe, it gained enormous influence through the French Revolution and through the First French Republic of 1792–1804.
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  • 12 Oct 2022
Topic Review
Methods for Recycling Heterogenous Catalysts
The rapid separation and efficient recycling of catalysts after a catalytic reaction are considered important requirements along with the high catalytic performances. In this view, although heterogeneous catalysis is generally less efficient if compared to the homogeneous type, it is generally preferred since it benefits from the easy recovery of the catalyst. Recycling of heterogeneous catalysts using traditional methods of separation such as extraction, filtration, vacuum distillation, or centrifugation is tedious and time-consuming. They are uneconomic processes and, hence, they cannot be carried out in the industrial scale.
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  • 23 Jun 2021
Topic Review
Routing Protocol for Low Power and Lossy Network
The IETF Routing Over Low power and Lossy network (ROLL) working group defined IPv6 Routing Protocol for Low Power and Lossy Network (RPL) to facilitate efficient routing in IPv6 over Low-Power Wireless Personal Area Networks (6LoWPAN). Limited resources of 6LoWPAN nodes make it challenging to secure the environment, leaving it vulnerable to threats and security attacks. Machine Learning (ML) and Deep Learning (DL) approaches have shown promise as effective and efficient mechanisms for detecting anomalous behaviors in RPL-based 6LoWPAN.
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  • 19 May 2022
Topic Review
Italic Languages
The Italic languages are a subfamily of the Indo-European language family, originally spoken by Italic peoples. They include Latin and its descendants (the Romance languages) as well as a number of extinct languages of the Italian Peninsula, including Umbrian, Oscan, Faliscan, South Picene, and possibly Venetic and Sicel. With over 800 million native speakers, the Italic languages are the second most widely spoken branch of the Indo-European family, after the Indo-Iranian languages. In the past, various definitions of "Italic" have prevailed. This article uses the classification presented by the Linguist List: Italic includes the Latin subgroup (Latin and the Romance languages) as well as the ancient Italic languages (Faliscan, Osco-Umbrian and two unclassified Italic languages, Aequian and Vestinian). Venetic (the language of the ancient Veneti), as revealed by its inscriptions, shared some similarities with the Italic languages and is sometimes classified as Italic. However, since it also shares similarities with other Western Indo-European branches (particularly Celtic languages), some linguists prefer to consider it as an independent Indo-European language. In the extreme view, Italic did not exist, but the different groups descended directly from Indo-European and converged because of geographic contiguity. That view stems in part from the difficulty in identifying a common Italic homeland in prehistory. In the intermediate view, the Italic languages are one of the ten or eleven major subgroups of the Indo-European language family and might therefore have had an ancestor, Common Italic or Proto-Italic from which its daughter languages descended. Moreover, there are similarities between major groups, but how the similarities are to be interpreted is one of the major debated issues in the historical linguistics of Indo-European. The linguist Calvert Watkins went so far as to suggest, among the ten major groups, a four-way division of East, West, North and South Indo-European. He considered them to be "dialectical divisions within Proto-Indo-European which go back to a period long before the speakers arrived in their historical areas of attestation". It is not to be considered a nodular grouping; in other words, there was not necessarily any common west Indo-European serving as a node from which the subgroups branched but a hypothesised similarity between the dialects of Proto-Indo-European that developed into the recognised families. Although generally regarded as a single branch that diversified from a Common or Proto-Italic stage, after the Proto-Indo-European period, some authors doubt this common affiliation. All the Italic languages share a number of common isoglosses; thus, all of them are centum languages that do not present palatalization of the Indo-European (palatal) velars /*k, *kʷ, *g, *gʰ, *gʰʷ/. The Romance languages present a later palatalization of Latin phonemes /k, g/, although only before phonemes /ɛ, e, i/.
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  • 17 Nov 2022
Topic Review
Conventional Liposomal Formulation Methods
Liposome-based drug delivery systems are nanosized spherical lipid bilayer carriers that can encapsulate a broad range of small drug molecules (hydrophilic and hydrophobic drugs) and large drug molecules (peptides, proteins, and nucleic acids). They have unique characteristics, such as a self-assembling bilayer vesicular structure. There are various methods used in the preparation of lipid-based nanocarriers such as liposomes. The method of preparation affects critical parameters such as size of vesicle and size distribution, permeability, lamellarity, and entrapment efficiency. Entrapment of compounds is performed by two main techniques; passive loading where drug entrapment occurs during the liposome formation, and active loading where drug entrapment is after the liposome formation.
  • 6.1K
  • 15 May 2023
Topic Review
Tether (Cryptocurrency)
Tether (often referred to by one of its currency codes, USD₮), is an asset-backed cryptocurrency stablecoin. It was launched by the company Tether Limited Inc. in 2014. Tether Limited is owned by the Hong Kong-based company iFinex Inc., which also owns the Bitfinex cryptocurrency exchange. As of July 2022, Tether Limited has minted the USDT stablecoin on ten protocols and blockchains. Tether is described as a stablecoin because it was originally designed to be valued at USD $1.00, with Tether Limited maintaining USD $1.00 of asset reserves for each USDT issued.
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  • 16 Nov 2022
Topic Review
Biodegradability of Starch and Starch Blends
Starch is one of the most abundant biodegradable biopolymers from renewable sources; it also contains tunable thermoplastic properties suitable for diverse applications in agriculture. Functional performances of starch such as physicomechanical, barrier, and surface chemistry may be altered for extended agricultural applications. Furthermore, starch can be a multidimensional additive for plasticulture that can function as a filler, a metaphase component in blends/composites, a plasticizer, an efficient carrier for active delivery of biocides and so on.
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  • 31 May 2022
Topic Review
Dynamic-Maturational Model of Attachment and Adaptation
The dynamic-maturational model of attachment and adaptation (DMM) is a transdisciplinary model describing the effect attachment relationships can have on human development and functioning. It is especially focused on the effects of relationships between children and parents and between romantic/reproductive couples. It developed initially from attachment theory as developed by John Bowlby and Mary Ainsworth, and incorporated many other theories into a comprehensive model of adaptation to life's many dangers. The DMM was initially created by developmental psychologist Patricia McKinsey Crittenden and her colleagues including David DiLalla, Angelika Claussen, Andrea Landini, Steve Farnfield, and Susan Spieker. A main tenant of the DMM is that exposure to danger drives neural development and adaptation to promote survival. Danger includes relationship danger. In DMM-attachment theory, when a person needs protection or comfort from danger from a person with whom they have a protective relationship, the nature of the relationship generates relation-specific self-protective strategies. These are patterns of behavior which include the underlying neural processing. The DMM protective strategies describe aspects of the parent-child relationship, romantic relationships, and to a degree, relationships between patients/clients and long-term helping professionals.
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  • 22 Nov 2022
Topic Review
Wood Formation in Plants
Unlike herbaceous plants, woody plants undergo volumetric growth (a.k.a. secondary growth) through wood formation, during which the secondary xylem (i.e., wood) differentiates from the vascular cambium. Wood is the most abundant biomass on Earth and, by absorbing atmospheric carbon dioxide, functions as one of the largest carbon sinks. As a sustainable and eco-friendly energy source, lignocellulosic biomass can help address environmental pollution and the global climate crisis.
  • 6.0K
  • 15 Jul 2022
Topic Review
Classification of the Approved EGFR-TKIs
Targeting EGFR with small-molecule inhibitors is a valid strategy in cancer therapy. Since the approval of the first EGFR-TKI in 2003, a huge number of EGFR inhibitors were reported. Classification of these inhibitors could help the researchers to understand their structure-activity relationship. Herein, we introduce different types of classifications of the EGFR-TKIs, which received global approval for clinical use. In the following, the EGFR-targeting drugs are classified based on their chemistry, clinical use, target kinases, and the type of inhibition/interaction with EGFR. 
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  • 25 Nov 2021
Topic Review
Ivermectin during the COVID-19 Pandemic
Ivermectin (IVM) is a broad-spectrum antiparasitic agent, developed and funded by Merck & Co. in 1974 to control and eradicate onchocerciasis caused by the parasitic worm Onchocerca volvulus in West Africa, which in the 1980s infected approximately 340,000 people. At the time, Africa did not have the resources necessary to seek treatments for this condition. The avermectins, of which IVM is a member, were discovered by Professor Satoshi Ōmura as fermentation products of the bacterium Streptomyces avermitilis at the Kitasato Institute in Tokyo. For this discovery, he received the 2015 Nobel Prize in Physiology and Medicine, which he shared with William Campbell. IVM is used to treat onchocerciasis, lymphatic filariasis, strongyloidiasis and scabies, and, very recently, has been used to combat lice. The drug’s low cost, high efficacy, safety, and marked tropism for helminths, as well as the fact that it has almost no impact on human biochemistry, have led to the inclusion of IVM in the twentieth list of essential medicines and sixth list of vital medicines in children, a recommendation made by the expert committee of the World Health Organization (WHO) in 2019. The safety profile is attributed to its selective affinity for ion channels.
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  • 22 Sep 2022
Topic Review
Autonomous Spaceport Drone Ship
An autonomous spaceport drone ship (ASDS) is an ocean-going vessel derived from a deck barge, outfitted with station-keeping engines and a large landing platform. Construction of such ships was commissioned by aerospace company SpaceX to allow for recovery of rocket first-stages at sea for high-velocity missions which do not carry enough fuel to return to the launch site after lofting spacecraft onto an orbital trajectory. SpaceX has two operational drone ships and has a third under construction as of early 2018. Just Read the Instructions operates in the Pacific for launches from Vandenberg Air Force Base ; Of Course I Still Love You operates in the Atlantic for launches from Cape Canaveral. A Shortfall of Gravitas is under construction. (As of August 2018), 23 Falcon 9 flights have attempted to land on a drone ship, with 17 of them succeeding. The ASDS ships are a key component of the SpaceX reusable launch system development program which aims to significantly lower the price of space launch services through "full and rapid reusability." Any flights going to geostationary orbit or exceeding escape velocity will require landing at sea, encompassing about half of SpaceX missions.
  • 6.0K
  • 27 Oct 2022
Topic Review
Tattvartha Sutra
Tattvartha Sutra (also known as Tattvarth-adhigama-sutra or Moksha-shastra) is an ancient Jain text written by Acharya Umaswami (Umaswami), sometime between the 2nd- and 5th-century AD. It is one of the Jain scriptures written in the Sanskrit language. The term Tattvartha is composed of the Sanskrit words tattva which means "reality, truth" and artha which means "nature, meaning", together meaning "nature of reality". The Tattvartha Sutra is regarded as one of the earliest, most authoritative texts in Jainism. It is accepted as authoritative in both its major sub-traditions – Digambara and Śvētāmbara – as well as the minor sub-traditions. It is a philosophical text, and its importance in Jainism is comparable with that of the Brahma Sutras and Yoga Sutras of Patanjali in Hinduism. In an aphoristic sutra style of ancient Indian texts, it presents the complete Jainism philosophy in 350 sutras over 10 chapters. The text has attracted numerous commentaries, translations and interpretations since the 5th-century. One of its sutras, Parasparopagraho Jivanam is the motto of Jainism. Its meaning is interpreted as "(The function) of souls is to help one another", or "Souls render service to one another".
  • 6.0K
  • 03 Nov 2022
Topic Review
Division of Labour
The division of labour is the separation of tasks in any economic system or organisation so that participants may specialise (specialisation). Individuals, organizations, and nations are endowed with or acquire specialised capabilities and either form combinations or trade to take advantage of the capabilities of others in addition to their own. Specialised capabilities may include equipment or natural resources as well as skills and training and combinations of such assets acting together are often important. For example, an individual may specialise by acquiring tools and the skills to use them effectively just as an organization may specialize by acquiring specialised equipment and hiring or training skilled operators. The division of labour is the motive for trade and the source of economic interdependence. Historically, an increasing division of labour is associated with the growth of total output and trade, the rise of capitalism, and the increasing complexity of industrialised processes. The concept and implementation of division of labour has been observed in ancient Sumerian (Mesopotamian) culture, where assignment of jobs in some cities coincided with an increase in trade and economic interdependence. Division of labour generally also increases both producer and individual worker productivity. After the Neolithic Revolution, pastoralism and agriculture led to more reliable and abundant food supplies, which increased the population and led to specialisation of labour, including new classes of artisans, warriors, and the development of elites. This specialistion was furthered by the process of industrialisation, and Industrial Revolution-era factories. Accordingly, many classical economists as well as some mechanical engineers such as Charles Babbage were proponents of division of labour. Also, having workers perform single or limited tasks eliminated the long training period required to train craftsmen, who were replaced with lesser paid but more productive unskilled workers.
  • 6.0K
  • 17 Oct 2022
Topic Review
Biocoagulant/bioflocculant application for drinking water
The utilization of metal-based conventional coagulants/flocculants to remove suspended solids from drinking water and wastewater is currently leading to new concerns. Alarming issues related to the prolonged effects on human health and further pollution to aquatic environments from the generated nonbiodegradable sludge are becoming trending topics. The utilization of biocoagulants/bioflocculants does not produce chemical residue in the effluent and creates nonharmful, biodegradable sludge.
  • 6.0K
  • 25 Dec 2020
Topic Review
Michael Addition of Carbonyl Compounds to α,β-Unsaturated Nitroalkenes
The proline-catalyzed asymmetric Michael addition reaction of acetaldehyde with α,β-unsaturated nitroalkenes as synthetically useful routes to β-substituted derivatives of γ-Aminobutyric acid (GABA).
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  • 01 Jul 2022
Topic Review
Organ
In biology, an organ is a collection of tissues joined in a structural unit to serve a common function. In the hierarchy of life, an organ lies between tissue and an organ system. Tissues are formed from same type cells to act together in a function. Tissues of different types combine to form an organ which has a specific function. The intestinal wall for example is formed by epithelial tissue and smooth muscle tissue. Two or more organs working together in the execution of a specific body function form an organ system, also called a biological system or body system. An organ's tissues can be broadly categorized as parenchyma, the functional tissue, and stroma, the structural tissue with supportive, connective, or ancillary functions. For example, the gland's tissue that makes the hormones is the parenchyma, whereas the stroma includes the nerves that innervate the parenchyma, the blood vessels that oxygenate and nourish it and carry away its metabolic wastes, and the connective tissues that provide a suitable place for it to be situated and anchored. The main tissues that make up an organ tend to have common embryologic origins, such as arising from the same germ layer. Organs exist in most multicellular organisms. In single-celled organisms such as bacteria, the functional analogue of an organ is known as an organelle. In plants, there are three main organs. In the study of anatomy, viscera (singular viscus) refers to the internal organs of the abdominal, thoracic, and pelvic cavities. The abdominal organs may be classified as solid organs, or hollow organs. The solid organs are the liver, pancreas, spleen, kidneys, and adrenal glands. The hollow organs of the abdomen are the stomach, intestines, gallbladder, bladder, and rectum. In the thoracic cavity the heart is a hollow, muscular organ. The number of organs in any organism depends on the definition used. By one widely adopted definition, 79 organs have been identified in the human body.
  • 6.0K
  • 14 Oct 2022
Topic Review
Diarchy
A diarchy (from Greek δι-, di-, "double", and -αρχία, -arkhía, "ruled")[note 1] or duumvirate (from Latin duumvirātus, "the office of the two men")[note 2] is a form of government characterized by corule, with two people ruling a polity together either lawfully or de facto, by collusion and force. The leaders of such a system are usually known as corulers. Historically, diarchy particularly referred to the system of shared rule in British India established by the Government of India Acts 1919 and 1935, which devolved some powers to local councils, which had included native Indian representation under the Indian Councils Act 1892. 'Duumvirate' principally referred to the offices of the various duumviri established by the Roman Republic. Both, along with less common synonyms such as biarchy and tandemocracy,[note 3] are now used more generally to refer to any system of joint rule or office. A monarchy temporarily controlled by two or more people is, however, usually distinguished as a coregency. Corule is one of the oldest forms of government. Historical examples include the Pandyan dynasty of Tamilakam, Sparta's joint kingdom, the Roman Republic's consuls, Carthage's Judges, and several ancient Polynesian societies. Systems of inheritance that often led to corule in Germanic and Dacian monarchies may be included as well, as may the dual occupants of the ranks of the Inca Empire. Modern examples of diarchies are Andorra, whose princes are the President of France and the Bishop of Urgell in Catalonia; and San Marino, whose republic is led by two Captains Regent.
  • 6.0K
  • 14 Nov 2022
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