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Topic Review
Association between Smoking and Obstructive Sleep Apnea
The connection between smoking and Obstructive sleep apnea (OSA) is not yet clear. There are studies that have confirmed the effect of smoking on sleep disordered breathing, whereas others did not. Nicotine affects sleep, as smokers have prolonged total sleep and REM latency, reduced sleep efficiency, total sleep time, and slow wave sleep. Smoking cessation has been related with impaired sleep. 
  • 1.5K
  • 14 Sep 2022
Topic Review
Virtual Screening Algorithms in Drug Discovery
Virtual screening (VS) is an in silico technique used in the drug discovery process. During VS, large databases of molecular structures are automatically evaluated using computational methods. With the use of VS, it is expected to identify molecules more susceptible to binding to the molecular target, typically a protein or enzyme receptor.
  • 1.5K
  • 29 May 2023
Topic Review
L. reuteri in Human Gut
Lactobacillus reuteri DSM 17938 (L. reuteri) is a probiotic that can colonize different human body sites, including primarily the gastrointestinal tract, but also the urinary tract, the skin, and breast milk. Literature data showed that the administration of L. reuteri can be beneficial to human health. 
  • 1.5K
  • 13 Jul 2021
Topic Review
CAL Schistocerca piceifrons piceifrons Management
The Central American locust (CAL), Schistocerca piceifrons piceifrons (Walker, 1870), is a transboundary pest that is distributed from Mexico to Panama. It is a true locust species characterized by density-dependent phase polyphenism. The ancient record of the CAL is found in the Popol Vuh, the Mayan sacred book, demonstrating how it has affected humans for millennia. In Mexico, the CAL has been declared a national threat to agriculture since 1824. Serious locust plagues occurred in 1882–1883 when swarms of 20 km2 in size invaded the Yucatán Peninsula and neighboring states in southern Mexico and, since then, management actions to suppress populations and economic damage have been implemented. A better understanding of the biology, ecology, and behavior of the CAL replaced a manual and mechanical collection of locust swarms, hopper bands, and egg pods with modern techniques such as the use of safer chemical products and environmentally friendly bioinsecticides. Presently, biomodels and GIS support the monitoring and forecasting of outbreaks.
  • 1.5K
  • 01 Jun 2021
Topic Review
Heteromeric TRP Channels
Heteromeric Transient Receptor Potential (TRP) channels build a tetrameric structure with at least one TRP subunit from another subfamily. In pulmonary microvascular endothelial cells their activation can disrupt endothelial barrier function, as their mediated calcium influx activates the CaM (calmodulin)/MLCK (myosin light chain kinase)-signaling pathway, and thereby rearranges the cytoskeleton, increases endothelial permeability and thus can facilitate activation of inflammatory cells and formation of pulmonary edema.
  • 1.5K
  • 06 Jul 2021
Topic Review
Sonic Environment and Noise Mitigations
The pandemic has impacted every facet of our life, society, and environment. It has also affected both the requirement and challenges for acoustic research and applications. The present article attempts to present a summary of the impact of COVID-19 on several aspects of acoustics, from the changes in the sonic environment due to reduced human and industrial activities to natural ventilation requirements for mitigating the transmission of coronavirus while mitigating noise, and, more importantly, discusses the potential impacts and challenges for acoustics in the post-COVID-19 era. The present study specifically examines the effects of COVID-19 on the sonic environment, the acoustic treatment by considering the need for constant disinfection, the noise control on construction and neighborhood activities in response to an increased number of people working from home, and the need for having natural ventilation while mitigating noise at home and offices. 
  • 1.5K
  • 26 Jul 2021
Topic Review
K2P Potassium Channels to Cardiac
Two-pore domain potassium (K2P) channels are the latest potassium channels family to be described. Since the discovery of the first member of the TWIK subfamily, the 15 known K2P channels cloned to date have been grouped into six different subfamilies: TIWK; TREK; TASK; THIK; TRESK; and TALK. In mammals, K2P channels are expressed in both nervous and non-nervous tissue, and their distribution varies widely from the almost ubiquitous expression of TWIK to the weak pancreatic expression of TALK.
  • 1.5K
  • 18 Aug 2021
Topic Review
Green Port Implementation in Indonesia and Circular Economy
Several public seaports and fishing terminals are located in the same port complex but have different fragmented operations such as waste management. It is possible to provide a new initiative to ensure sustainability for all entities in the surrounding port ecosystem through the application of Green Port using the circular economy approach and mixed linear programming model. It was discovered that the integration model has the potential to generate new energy by recycling waste from all related entities in the production of a few main fishing products such as tuna, sardine, and squid, as well as vessel traffic, facilities, and cargo flow interactions in addition to other port operations.
  • 1.5K
  • 06 Jun 2022
Topic Review
African-American Studies
African-American studies (alternately named Afroamerican studies, or in US education, black studies) is an interdisciplinary academic field that is primarily devoted to the study of the history, culture, and politics of black people from the United States . African American studies are a sub-field of African diaspora studies and Africana studies, the study of the people of African origin worldwide. The field has been defined in different ways, but taken broadly, it not only studies African slave descendants but also any community of the African diaspora linked to the Americas. The field includes scholars of African-American (as well as Caribbean, African, and Afro-European) literature, history, politics, and religion as well as those from disciplines such as sociology, anthropology, cultural studies, psychology, education, and many other disciplines within the humanities and social sciences. And, increasingly, African-American Studies departments are hiring and partnering with STEM scholars. Intensive academic efforts to reconstruct African American history began in the late 19th century (W. E. B. Du Bois, The Suppression of the African Slave-trade to the United States of America, 1896). Among the pioneers in the first half of the 20th century were Carter G. Woodson, Herbert Aptheker, Melville Herskovits, and Lorenzo Dow Turner. Programs and departments of African American Studies were first created in the 1960s and 1970s as a result of inter-ethnic student and faculty activism at many universities, sparked by a five-month strike for black studies at San Francisco State. In February 1968, San Francisco State hired sociologist Nathan Hare to coordinate the first black studies program and write a proposal for the first Department of Black Studies; the department was created in September 1968 and gained official status at the end of the five-months strike in the spring of 1969. The creation of programs and departments in black studies was a common demand of protests and sit-ins by minority students and their allies, who felt that their cultures and interests were underserved by the traditional academic structures. Black studies is a systematic way of studying black people in the world – such as their history, culture, sociology, policies, experience, issues and religion. It is a study of the black experience and the effect of society on them and their effect within society. This study aims to, among other things, help eradicate many racial stereotypes. Black studies implements history, family structure, social and economic pressures, stereotypes, and gender relationships.
  • 1.5K
  • 17 Oct 2022
Topic Review
Polyunsaturated Fat
Polyunsaturated fats are fats in which the constituent hydrocarbon chain possesses two or more carbon–carbon double bonds. Polyunsaturated fat can be found mostly in nuts, seeds, fish, seed oils, and oysters. "Unsaturated" refers to the fact that the molecules contain less than the maximum amount of hydrogen (if there were no double bonds). These materials exist as cis or trans isomers depending on the geometry of the double bond. Saturated fats have hydrocarbon chains which can be most readily aligned. The hydrocarbon chains in trans fats align more readily than those in cis fats, but less well than those in saturated fats. In general, this means that the melting points of fats increase from cis to trans unsaturated and then to saturated. See the section about the chemical structure of fats for more information. The position of the carbon-carbon double bonds in carboxylic acid chains in fats is designated by Greek letters. The carbon atom closest to the carboxyl group is the alpha carbon, the next carbon is the beta carbon and so on. In fatty acids the carbon atom of the methyl group at the end of the hydrocarbon chain is called the omega carbon because omega is the last letter of the Greek alphabet. Omega-3 fatty acids have a double bond three carbons away from the methyl carbon, whereas omega-6 fatty acids have a double bond six carbons away from the methyl carbon. The illustration below shows the omega-6 fatty acid, linoleic acid. While it is the nutritional aspects of polyunsaturated fats that are generally of greatest interest, these materials also have non-food applications. Drying oils, which polymerize on exposure to oxygen to form solid films, are polyunsaturated fats. The most common ones are linseed (flax seed) oil, tung oil, poppy seed oil, perilla oil, and walnut oil. These oils are used to make paints and varnishes.
  • 1.5K
  • 24 Oct 2022
Topic Review
Classification of Non-Destructive Evaluation
Inspection methods, also known as non-destructive evaluation (NDE), is a process for inspecting materials, products, and facilities to identify flaws, imperfections, and malfunctions without destruction or changing the integrity of materials, structures, and mechanisms.
  • 1.5K
  • 31 Oct 2022
Topic Review
Bathymetric Chart
A bathymetric chart is a type of isarithmic map that depicts the submerged topography and physiographic features of ocean and sea bottoms. Their primary purpose is to provide detailed depth contours of ocean topography as well as provide the size, shape and distribution of underwater features. Topographic maps display elevation above ground and are complementary to bathymetric charts. Charts use a series of lines and points at equal intervals to showcase depth or elevation. A closed shape with increasingly smaller shapes inside of it can indicate an ocean trench or a seamount, or underwater mountain, depending on whether the depths increase or decrease going inward.Bathymetric surveys and charts are associated with the science of oceanography, particularly marine geology, and underwater engineering or other specialized purposes. thumb|Bathymetric Map of Medicine Lake, CABathymetric data used to produce charts can also be converted to bathymetric profiles which are vertical sections through a feature.thumb|right|Bathymetric chart of Bear Lake
  • 1.5K
  • 03 Nov 2022
Topic Review
Suzuki TT Superbikes: Real Road Racing Championship
Suzuki TT Superbikes: Real Road Racing, often shortened to simply Suzuki TT Superbikes; also known as TT Superbikes: Real Road Racing in Europe and Japan, is a 2005 motorcycle simulation racing video game developed by Jester Interactive exclusively for the PlayStation 2 gaming console. The game was self–published by Jester in Europe, with Valcon Games and Taito handling publishing in North America and Japan, respectively. In North America, the game is licensed under Suzuki, an automobile manufacturer. The title features over 50 licensed vehicles and is entirely based around the famed Isle of Man TT race, a 60.72 km annual competition held within the Isle of Man. It is the second game based on the race, following the 1995 release of Manx TT Super Bike, though this game was only based on the Manx TT event, which is a small section of the course. The game was available on the PlayStation 3 via the North American PlayStation Store. Suzuki TT Superbikes has since received two sequels.
  • 1.5K
  • 01 Dec 2022
Topic Review
Vibrotactile Feedback in Virtual Reality
While substantial progress in computer graphics and sound rendering has resulted in highly realistic visual and auditory experiences in virtual reality (VR), achieving genuine immersion, interactivity, and the stimulation of imagination necessitates the integration of realistic tactile experiences, often facilitated through haptic feedback. The incorporation of vibrotactile feedback in VR allows users to fully engage their sense of touch, enabling them to explore, grasp, and manipulate virtual objects as if they were interacting with them in the physical world.
  • 1.5K
  • 22 Jan 2024
Topic Review
Social Brain Perspectives on Neuroscience of Human Language
Human language and social cognition are two key disciplines that have traditionally been studied as separate domains. Nonetheless, an emerging view suggests an alternative perspective. Drawing on the theoretical underpinnings of the social brain hypothesis (thesis of the evolution of brain size and intelligence), the social complexity hypothesis (thesis of the evolution of communication), and empirical research from comparative animal behavior, human social behavior, language acquisition in children, social cognitive neuroscience, and the cognitive neuroscience of language, it is argued that social cognition and language are two significantly interconnected capacities of the human species. 
  • 1.5K
  • 21 Feb 2024
Topic Review
Ensembl Genomes
Ensembl Genomes is a scientific project to provide genome-scale data from non-vertebrate species. The project is run by the European Bioinformatics Institute, and was launched in 2009 using the Ensembl technology. The main objective of the Ensembl Genomes database is to complement the main Ensembl database by introducing five additional web pages to include genome data for bacteria, fungi, invertebrate metazoa, plants, and protists. For each of the domains, the Ensembl tools are available for manipulation, analysis and visualization of genome data. Most Ensembl Genomes data is stored in MySQL relational databases and can be accessed by the Ensembl Perl API, virtual machines or online. Ensembl Genomes is an open project, and most of the code, tools, and data are available to the public. Ensembl and Ensembl Genomes software uses a "permissive Apache-style open-source" license, making it free for all users.
  • 1.5K
  • 19 Oct 2022
Topic Review
Helmet Design and Neurotrauma Prevention
Neurotrauma is an important, often preventable cause of morbidity and mortality. Between 180 and 250 traumatic brain injuries (TBIs) occur per 100,000 population per year in the U.S.. Helmets have been employed by humans for thousands of years and have served as a crucial instrument by which we protect ourselves from and minimize the effects of traumatic brain injury. Substantial evidence from systematic reviews and meta-analyses points toward the protective effectiveness (often >60%) of helmets in preventing TBIs in athletes, cyclists and motorcyclists. However, when stratifying TBI by severity, helmets may be less effective or even ineffective in preventing milder forms of TBI such as concussion. Helmet design has been predicated on linear acceleration as a metric corresponding to head injury. This has served well in preventing catastrophic injuries. However, rotational acceleration is more likely implicated in the pathophysiology of milder brain injuries, including concussion.
  • 1.5K
  • 30 Sep 2022
Topic Review
Structure and Function of Matrix Metalloproteinase-9
Matrix metalloproteinases (MMPs) belong to a family of zinc-dependent proteolytic metalloenzymes. MMP-9, a member of the gelatinase B family, is characterized as one of the most intricate MMPs. The crucial involvement of MMP-9 in extracellular matrix (ECM) remodeling underscores its significant correlation with each stage of cancer pathogenesis and progression. The design and synthesis of MMP-9 inhibitors is a potentially attractive research area.
  • 1.5K
  • 07 Aug 2023
Topic Review
Geographic Information System
Geographic information systems (GIS) are composed of software, hardware, data, administrators, and methods for processing and analyzing data.  Creating and sharing spatial data in digital form is not only good practice but is also regulated by specific legal acts. Currently created in map portals and the widely available General Geographic Object Databases offer a reliable, current, and continuous source of spatial information for the entire country, extremely helpful in the planning process at various levels of generalization. The database implemented into the Spatial Information System is its most important element and should constitute a complete and reliable representation of elements of the real world.  GIS systems allow us to formulate models in a structured and formal way to reflect both the current situation and forecast changes that will occur in space when certain conditions are met. The proposed methodology can be used in practical applications:• Preparing planning studies, both regarding spatial policy and local law, as well as in economic planning and shaping the structure of rural space (structure of ownership and structure of use).• The development of thematic spatial information systems related to planning studies and works shaping the rural space.• Reports submitted to EU authorities relating to the utilization of funds dedicated to rural development in the multiannual financial framework and modification of the implemented actions.• The use of renewable energy sources to improve Poland’s energy security.
  • 1.5K
  • 19 Jan 2021
Topic Review
Organic Coatings for Marine Applications
Organic coatings for marine applications must have great corrosion protection and antifouling performance. This review presents an overview of recent investigations into coating microstructure, corrosion protection performance, antifouling behavior, and evaluation methods, particularly the substrate effect and environmental influence on coating protectiveness, aiming to improve operational practice in the coating industry. 
  • 1.5K
  • 21 Jan 2021
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