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Topic Review
Central Nervous System in Trichinellosis
Trichinellosis is a parasitic disease caused by the consumption of raw meat infected with larvae of nematode in the genus Trichinella. 
  • 1.5K
  • 22 Feb 2022
Topic Review
Fungal Depsides Naturally Inspiring Molecules
Depsides are a group of polyketides consisting of two or more ester-linked hydroxybenzoic acid moieties. They possess valuable bioactive properties, such as anticancer, antidiabetic, antibacterial, antiviral, anti-inflammatory, antifungal, antifouling, and antioxidant qualities, as well as various human enzyme-inhibitory activities.
  • 1.5K
  • 14 Oct 2021
Topic Review
Copy-number Variation
Copy number variation (CNV) is a phenomenon in which sections of the genome are repeated and the number of repeats in the genome varies between individuals. Copy number variation is a type of structural variation: specifically, it is a type of duplication or deletion event that affects a considerable number of base pairs. Approximately two-thirds of the entire human genome may be composed of repeats and 4.8–9.5% of the human genome can be classified as copy number variations. In mammals, copy number variations play an important role in generating necessary variation in the population as well as disease phenotype. Copy number variations can be generally categorized into two main groups: short repeats and long repeats. However, there are no clear boundaries between the two groups and the classification depends on the nature of the loci of interest. Short repeats include mainly bi-nucleotide repeats (two repeating nucleotides e.g. A-C-A-C-A-C...) and tri-nucleotide repeats. Long repeats include repeats of entire genes. This classification based on size of the repeat is the most obvious type of classification as size is an important factor in examining the types of mechanisms that most likely gave rise to the repeats, hence the likely effects of these repeats on phenotype.
  • 1.5K
  • 02 Nov 2022
Topic Review
Three Roots
The Three Roots (Tibetan: tsa sum) of the Tibetan Buddhist tradition are the lama (Sanskrit: guru), yidam (Sanskrit: ishtadevata) and protector, which may be a khandroma (Sanskrit: dakini) or chokyong (Sanskrit: dharmapala). The Three Roots are the second of three Tibetan Buddhist refuge formulations, the Outer, Inner and Secret forms of the Three Jewels. The 'Outer' form is the 'Triple Gem', (Sanskrit:triratna), the 'Inner' is the Three Roots and the 'Secret' form is the 'Three Bodies' or trikaya of a Buddha. These alternative refuge formulations are employed by those undertaking Deity Yoga and other tantric practices within the Tibetan Buddhist Vajrayana tradition as a means of recognizing the universality of Buddha Nature. The Three Roots are commonly mentioned in the Nyingma and Kagyu literature of Tibetan Buddhism. Unlike most aspects of Tibetan Buddhism, which originated in India, the Three Roots may be an original Tibetan formulation from the time of Padmasambhava. The functions of the Three Roots are: In the Yangzab compilation of Dzogchen texts the 'Yangzab Three Roots' is the primary Deity Yoga practice. The Three Roots in this cycle are: Guru Rinpoche (the guru), Hayagriva (the yidam), and Vajravarahi (the dakini). This empowerment is required for the practitioner to study the Yangzab Treasure teaching cycle. The three roots are symbolized in the Gankyil.
  • 1.5K
  • 09 Nov 2022
Topic Review
Articular Eminence and Temporomandibular Disorders
In order to determine the correlation between the inclination of articular eminence (AEI) and the development of temporomandibular disorders (TMDs), a systematic review was performed.
  • 1.5K
  • 13 Jan 2021
Topic Review
Fibroblast Growth Factor Receptor
Fibroblast growth factors (FGFs) are a family of 22 cell-signaling proteins of extracellular origin, generally released upon tissue injury, which act as systemic or locally circulating molecules capable of activating tyrosine-kinase receptors.
  • 1.5K
  • 02 Feb 2021
Topic Review
TiO2 for Removal of VOCs
Purification of air from the VOCs (Volatile Organic Compounds) by the photocatalytic process has been confirmed to be very perspective. Although many various photocatalysts have been prepared and studied so far, TiO2 is still the most commonly used, because of its advantageous properties such as non-toxicity, relatively low cost and high stability. Surface modifications of TiO2 were extensively proceeded in order to increase photocatalytic activity of the photocatalyst under both UV and visible light activations. High yield of VOCs decomposition can be achieved on TiO2, depending on its structure and preparation method. The contact time of reactant with the active sites of TiO2 surface will determinate the efficiency of the photocatalytic process. Although VOCs decomposition can occur under weak UV light, more intensive UV irradiation will guarante complete mineralisation process. 
  • 1.5K
  • 22 Apr 2021
Topic Review
Data Harmonization
Data harmonization (DH) corresponds to a field that unifies the representation of such a disparate nature of data. Over the years, multiple solutions have been developed to minimize the heterogeneity aspects and disparity in formats of big-data types.
  • 1.5K
  • 23 Sep 2021
Topic Review
Li-Ion Battery Technologies
Lithium-ion battery is a rechargeable battery, which mainly relies on the movement of lithium ions between the positive and negative electrodes to work. Lithium-ion batteries use an intercalated lithium compound as an electrode material. Currently, the main common cathode materials used as lithium ion batteries are: lithium cobalt oxide, lithium manganate, lithium nickelate and lithium iron phosphate.
  • 1.5K
  • 15 Nov 2021
Topic Review
Composite Attachments on Orthodontic Clear Aligners Therapy
Eight electronic databases were searched up to March 2020. Two authors independently proceeded to study selection, data extraction, and risk of bias assessment. The analysis of the results was carried out examining six groups of movements (mesio-distal tipping/bodily movement; anterior bucco-lingual tipping/root torque; posterior bucco-lingual tipping/expansion; intrusion; extrusion; rotation). Five clinical trials were selected and all of them showed a medium risk of bias. Literature showed that attachments mostly increase the effectiveness of orthodontic treatment with clear aligners, improving anterior root torque, rotation, and mesio-distal (M-D) movement; they are also important to increase posterior anchorage.
  • 1.5K
  • 18 Jan 2022
Topic Review
Ecosystem Services Potential of Endemic Floras
Natural, sustainable products arise in many fields, wild plants are reconsidered as providers of traditional or innovative applications. The notion of ecosystem services (ES) provides a frame to evaluate their benefits, but is still scarcely applied to endemic floras.
  • 1.5K
  • 31 May 2022
Topic Review
Affecting Erosion Factors
Erosion is a major issue since it results in several problems, such as failure/collapse, the degradation of surfaces, severe accidents, and vulnerabilities in many industrial systems and processes. Surface degradation by erosion is a slow but nevertheless continuous and unpreventable process in numerous industries, such as the oil and gas industry; erosion also affects aircraft, steam engines, and the rotor blades of power plant drive turbines, including wet-steam turbines, as well as other turbine plants that operate on wet steam.
  • 1.5K
  • 05 Jul 2022
Topic Review
Three-Phase
In electrical engineering, three-phase electric power systems have at least three conductors carrying alternating current voltages that are offset in time by one-third of the period. A three-phase system may be arranged in delta (∆) or star (Y) (also denoted as wye in some areas). A wye system allows the use of two different voltages from all three phases, such as a 230/400 V system which provides 230 V between the neutral (centre hub) and any one of the phases, and 400 V across any two phases. A delta system arrangement only provides one voltage magnitude, but it has a greater redundancy as it may continue to operate normally with one of the three supply windings offline, albeit at 57.7% of total capacity. Harmonic current in the neutral may become very large if nonlinear loads are connected.
  • 1.5K
  • 17 Oct 2022
Topic Review
IBM VisualAge
VisualAge was the name of a family of computer integrated development environments from IBM, which included support for multiple programming languages. VisualAge was first released in October 1993 and was discontinued on 30 April 2007 and its web page removed in September 2011. VisualAge was also marketed as “VisualAge Smalltalk”. IBM has stated that XL C/C++ is the 'follow-on' product to VisualAge.
  • 1.5K
  • 09 Nov 2022
Topic Review
Removal of Pesticides from Waters
Pesticides are pollutants found in wastewater due to increasing agricultural activities over the years. Inappropriate dosing of pesticides results in the dispersal of active ingredients in the environment. The complete removal of pesticides from wastewater is an immediate concern due to their high toxicity and mobility. At present, adsorption is one of the most widely used methods for pesticide removal, in which synthetic zeolites and mesoporous silica materials are extensively applied. This article presents a systematic and comparative review of the applications and comparison of these adsorbents, based on the data reported in the literature.
  • 1.5K
  • 07 Jul 2021
Topic Review
Reactive Oxygen and Nitrogen Species
Oxidative stress is the result of an imbalance between the presence of reactive oxygen species (ROS) and the ability of a biological system to detoxify them and their side products. Similarly, nitrosative stress is an imbalance of reactive nitrogen species (RNS). Some of these molecules can play an important role in signalization in both eukaryotes and prokaryotes.
  • 1.5K
  • 16 May 2022
Topic Review
MmpL3 Inhibition in Thearaphy of Tuberculosis
Tuberculosis (TB) is a contagious bacterial illness known to humankind since ancient times. The causal microorganism of TB is Mycobacterium tuberculosis (Mtb). Lung or pulmonary TB is the most common form, but Mtb also affects other body parts. TB does not spare any age group and is omnipresent worldwide. Most TB patients remain asymptomatic (latent TB) and non-contagious. However, approximately 10% of latent TB cases may advance to active TB (active or symptomatic TB). Some usual symptoms of active TB comprise continuing chronic cough, hemoptysis, night sweating, and weight loss. Active TB is associated with a high mortality rate if left untreated. The 2021 TB report of the World Health Organization (WHO) states that TB is one of the top 10 reasons for global deaths, about one-quarter of the global population is affected by Mtb, and the global burden of TB is expected to increase due to the COVID-19 pandemic.
  • 1.5K
  • 24 Nov 2022
Topic Review
Quality Attributes in Centella asiatica(L.) Urban
Centella asiatica is well known for its miraculous therapeutic properties in various systems of traditional medicine across the world. However, significant variation in its pharmacological activities has been reported due to the unavailability of quality raw material and non-standardized formulations. A number of research papers have been published on the collection of C. asiatica plants from different regions for the identification of a suitable agroclimate with elite germplasms. Efforts have been made to standardize production and post-harvest practices for the availability of quality raw material with a high centelloside content. 
  • 1.5K
  • 29 Aug 2023
Topic Review
Cementitious and Geopolymer Composites with Lithium Slag Incorporation
Lithium slag (LS)’s particle size distribution is comparable to fly ash (FA) and ground granulated blast furnace slag (GGBS), which suggests it can enhance densification and nucleation in concrete. The mechanical treatment of LS promotes early hydration by increasing the solubility of aluminum, lithium, and silicon. LS’s compositional similarity to FA endows it with low-calcium, high-reactivity properties that are suitable for cementitious and geopolymeric applications. Increasing the LS content reduces setting times and flowability while initially enhancing mechanical properties, albeit with diminishing returns beyond a 30% threshold. LS significantly improves chloride ion resistance and impacts drying shrinkage variably. 
  • 1.5K
  • 08 Jan 2024
Topic Review
DYRK kinase family in cancer
       DYRK (dual-specificity tyrosine-regulated kinases) are an evolutionary conserved family of protein kinases with members from yeast to humans. In humans, DYRKs are pleiotropic factors that phosphorylate a broad set of proteins involved in many different cellular processes, including those associated with all the hallmarks of cancer. In accordance with an involvement of DYRK kinases in the regulation of tumorigenic processes, an increasing number of research studies are showing either alterations of DYRK gene expression in tumor samples and/or providing evidence of DYRK-dependent mechanisms that contribute to tumor initiation and/or progression.
  • 1.5K
  • 28 Aug 2020
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