Your browser does not fully support modern features. Please upgrade for a smoother experience.
Subject:
All Disciplines Arts & Humanities Biology & Life Sciences Business & Economics Chemistry & Materials Science Computer Science & Mathematics Engineering Environmental & Earth Sciences Medicine & Pharmacology Physical Sciences Public Health & Healthcare Social Sciences
Sort by:
Most Viewed Latest Alphabetical (A-Z) Alphabetical (Z-A)
Filter:
All Topic Review Biography Peer Reviewed Entry Video Entry
Topic Review
Therapeutic Potential of Marine Peptides in Prostate Cancer
Prostate cancer (PCa) is the leading cause of cancer death in men, and its treatment is commonly associated with severe adverse effects. Thus, new treatment modalities are required. In this context, natural compounds have been widely explored for their anti-PCa properties. Aquatic organisms contain numerous potential medications. Anticancer peptides are less toxic to normal cells and provide an efficacious treatment approach via multiple mechanisms, including altered cell viability, apoptosis, cell migration/invasion, suppression of angiogenesis and microtubule balance disturbances.
  • 1.5K
  • 01 Aug 2022
Topic Review
Be-Al Alloy
Be-Al alloy is a type of in situ metal matrix composite composed of a primary Be phase for strength and stiffness and a continuous Al matrix for ductility and toughness. Be-Al alloy  has the characteristics of low density (2.1-2.2 g/cm3), high elastic modulus (＞170 GPa) and specific stiffness (＞88 GPa/(g/cm3)) as a preferred material for lightweight aerospace products.
  • 1.5K
  • 05 Sep 2022
Topic Review
Aprotinin
The drug aprotinin (Trasylol, previously Bayer and now Nordic Group pharmaceuticals), is a small protein bovine pancreatic trypsin inhibitor (BPTI), or basic trypsin inhibitor of bovine pancreas, which is an antifibrinolytic molecule that inhibits trypsin and related proteolytic enzymes. Under the trade name Trasylol, aprotinin was used as a medication administered by injection to reduce bleeding during complex surgery, such as heart and liver surgery. Its main effect is the slowing down of fibrinolysis, the process that leads to the breakdown of blood clots. The aim in its use was to decrease the need for blood transfusions during surgery, as well as end-organ damage due to hypotension (low blood pressure) as a result of marked blood loss. The drug was temporarily withdrawn worldwide in 2007 after studies suggested that its use increased the risk of complications or death; this was confirmed by follow-up studies. Trasylol sales were suspended in May 2008, except for very restricted research use. In February 2012 the European Medicines Agency (EMA) scientific committee reverted its previous standpoint regarding aprotinin, and has recommended that the suspension be lifted. Nordic became distributor of aprotinin in 2012.
  • 1.5K
  • 20 Oct 2022
Topic Review
Abdominal Exercise
Abdominal exercises are type of strength exercise those that affect the abdominal muscles (colloquially known as the stomach muscles or "abs").
  • 1.5K
  • 04 Nov 2022
Topic Review
Motility of Helicobacter spp.
Helicobacter spp., including the well-known human gastric pathogen H. pylori, can cause gastric diseases in humans and other mammals. They are Gram-negative bacteria that colonize the gastric epithelium and use their multiple flagella to move across the protective gastric mucus layer. Different Helicobacter spp. differ in the number and arrangement of flagella, as well as in the size and shape of their cell body. The most well-studied of these is H. pylori, which is unipolar and lophotrichous (multiple flagella at one pole). Some of these bacteria are bipolar, e.g., the lophotrichous H. suis, and the monotrichous H. cetorum. The motility of H. pylori, H. suis, and H. cetorum was described in the review in Microorganisms 2023 linked above. 
  • 1.5K
  • 20 Mar 2023
Topic Review
Mechanical Heart Valve Patients with Intracranial Hemorrhage
The management of an intracranial hemorrhage in patients receiving anticoagulant therapy presents a significant challenge for medical professionals. Anticoagulant treatment is intended to prevent blood clotting, but it can worsen active brain bleeds. Despite this risk, avoiding the prothrombotic state caused by mechanical heart valves remains crucial. 
  • 1.5K
  • 17 May 2023
Topic Review
Overview of the Development of ZnO-Based Varistors
Voltage surge protection devices (SPDs) or surge arresters rely on metal oxide varistors (MOVs) to safeguard electrical equipment in consumer electronics and industrial electric power systems against the destructive temporary overvoltages (TOVs) resulting from transient switching surges or lightning strikes. The primary function of voltage-sensitive MOVs in SPDs is to prevent the damage caused by high-energy transients by clamping or eliminating them when a surge occurs. These MOVs are mounted in parallel with the components that they are designed to protect.
  • 1.5K
  • 29 May 2023
Topic Review
Thermal-Hydraulic Performance and Optimization
In order to make the heat exchanger achieve high thermal hydraulic performance, researchers have made a lot of explorations. However, most studies only focus on thermal-hydraulic optimization of PCHE core geometric parameters and operating conditions, and pay little attention to the influence of head on flow distribution and flow heat transfer characteristics of PCHE. PCHE is considered as a potential choice of the S-CO2Brayton cycle system, so S-CO2is the most used working fluid in PCHE.
  • 1.5K
  • 24 Nov 2021
Topic Review
CD123
The interleukin-3 receptor alpha chain (IL-3R), more commonly referred to as CD123, is widely overexpressed in various hematological malignancies, including acute myeloid leukemia (AML), B-cell acute lymphoblastic leukemia, hairy cell leukemia, Hodgkin lymphoma and particularly, blastic plasmacytoid dendritic neoplasm (BPDCN). Importantly, CD123 is expressed at both the level of leukemic stem cells (LSCs) and more differentiated leukemic blasts, which makes CD123 an attractive therapeutic target. Various agents have been developed as drugs able to target CD123 on malignant leukemic cells and on the normal counterpart. Tagraxofusp (SL401, Stemline Therapeutics), a recombinant protein composed of a truncated diphtheria toxin payload fused to IL-3, was approved for use in patients with BPDCN in December of 2018 and showed some clinical activity in AML. Different monoclonal antibodies directed against CD123 are under evaluation as antileukemic drugs, showing promising results either for the treatment of AML minimal residual disease or of relapsing/refractory AML or BPDCN. 
  • 1.5K
  • 13 Sep 2021
Topic Review
Bangladesh Fisheries, SDGs and COVID-19
Fisheries and the aquaculture sector can play a significant role in the achievement of several of the goals of the 2030 Sustainable Development agenda. However, the current COVID-19 situation can negatively impact the fisheries sector, impeding the pace of the achievement of development goals. Therefore, this paper highlighted the performance and challenges of the fisheries sector in Bangladesh, emphasizing the impact of COVID-19 and the significance of this sector for achieving the Sustainable Development Goals (SDGs), through primary fieldwork and secondary data. The total fish production in the country has increased more than six times over the last three decades (7.54 to 43.84 lakh MT) with improved culture techniques and extension services. Inland closed water contributions have increased to 16%, while inland open water has declined to 10%, and marine fisheries have dropped to 6% over the past 18 financial years (2000–2001 to 2018–2019). COVID-19, a significant health crisis, has also affected various issues associated with aquatic resources and communities. Transportation obstacles and complexity in the food supply, difficulty in starting production, labour crisis, sudden illness, insufficient consumer demand, commodity price hikes, creditor’s pressure, and reduced income were identified as COVID-19 drivers affecting the fisheries sector. The combined effect of these drivers poses a significant threat to a number of the SDGs, such as income (SDG1), nutrition (SDG2), and food security (SDG3 and SDG12), which require immediate and comprehensive action. Several recommendations were discussed, the implementation of which are important to the achievement of the SDGs and the improved management of the aquatic sector (SDG14—life below, and SDG16—life above water).
  • 1.5K
  • 16 Sep 2021
Topic Review
Mindfulness for Preventing Psychosocial Risks
Mindfulness-based intervention programs in the context of the workplace must be supported by a synthesis of empirical evidence in which the heterogeneity of the different studies shows their efficacy. Meta-analytical studies are intended to overcome the deficiencies and contradictions found in the literature by analyzing the empirical evidence available [38]. This meta-analytical review emphasizes exactly which results the various interventions now show and what influence they exert on psychological variables of employees. Therefore, the main objective of this study was to analyze the efficacy of MBIs on psychological variables of employees.
  • 1.5K
  • 29 Oct 2020
Topic Review
Diesel Engines Emissions Reduction
Compression ignition engines play a significant role in the development of a country. They are widely used due to their innate properties such as high efficiency, high power output, and durability. However, they are considered one of the key contributors to transport-related emissions and have recently been identified as carcinogenic. Thus, it is important to modify the designs and processes before, during, and after combustion to reduce the emissions to meet the strict emission regulations.
  • 1.5K
  • 13 Apr 2021
Topic Review
Breast Milk
Breast milk is an unbeatable food that covers all the nutritional requirements of an infant in its different stages of growth up to six months after birth. But the advantages of breastfeeding go beyond nutrition and are unanimously defended by all health establishments. Preventive medicine could also benefit from knowledge of the mechanisms by which human milk improves human development.
  • 1.5K
  • 27 Apr 2021
Topic Review
Maastrichtian Vertebrates of Lbero-Armorica
The South-Pyrenean Basin (northeastern Spain) has yielded a rich and diverse record of Upper Cretaceous (uppermost Campanian−uppermost Maastrichtian) vertebrate fossils, including the remains of some of the last European dinosaurs prior to the Cretaceous-Paleogene (K-Pg) extinction event. In this work, we update and characterize the vertebrate fossil record of the Arén Sandstone and Tremp formations in the Western Tremp Syncline, which is located in the Aragonese area of the Southern Pyrenees. The transitional and continental successions of these sedimentary units are dated to the late Maastrichtian, and exploration of their outcrops has led to the discovery of numerous fossil remains (bones, eggshells, and tracks) of dinosaurs, including hadrosauroids, sauropods, and theropods, along with other tetrapods such as crocodylomorphs, testudines, pterosaurs, squamates, and amphibians. In particular, this fossil record contains some of the youngest lambeosaurine hadrosaurids (Arenysaurus and Blasisaurus) and Mesozoic crocodylomorphs (Arenysuchus and Agaresuchus subjuniperus) in Europe, complementing the lower Maastrichtian fossil sites of the Eastern Tremp Syncline.
  • 1.5K
  • 10 May 2021
Topic Review
Nanomaterials for Viral Diseases Diagnosis, Prevention, and Treatment
Nanomaterials can be tailored for specific uses by modulating physical and chemical properties, including size, morphology, surface charge, and solubility. Due to these controllable properties, nanomaterials have been used in biosensors to potentiate target-specific reactions that respond to biochemical environments, such as temperature, pH, and the presence of enzymes.
  • 1.5K
  • 14 Oct 2021
Topic Review
Dysregulated DNA Methylation
Epigenetic mechanisms, such as DNA methylation, histone modifications, and non-coding RNAs, are known regulators of gene expression and genomic stability in cell growth, development, and differentiation. Since epigenetic mechanisms can regulate several immune system elements, epigenetic alterations have been found in several autoimmune diseases.
  • 1.5K
  • 08 Dec 2021
Topic Review
Pandemic Nursing Framework for Nursing Homes During COVID-19
Nurses have played a vital role in the fight against COVID-19 by ensuring continuity in patient care and demonstrating clinical leadership in pandemic efforts. The pandemic nursing measures can be broadly classified into four groups: (1) infection surveillance and containment measures; (2) ensuring continuity in clinical care and operational support; (3) resource and administrative coordination; and (4) staff training and development. 
  • 1.5K
  • 29 Dec 2021
Topic Review
Testing in Microgrids
This entry covers testing in Microgrids. The most common strategies are described and some papers are critizied. Testing in Microgrids can be done in a variety of ways, among others digital simulation, co-simulation, Real-Time simulation (RTS) Hardware-In-the-Loop (HIL), Controller-Hardware-In-the-Loop (CHIL), Power-Hardware-In-the-Loop (PHIL) and emulators. To choose the desired strategy, the trade-off has to be made between the cost, test fidelity and test coverage. The entry is based on section in "Testing Smart Grid Scenarios with Small Volume Testbed and Flexible Power Inverter" by Milosz Krysik et al.  
  • 1.5K
  • 12 Jan 2022
Topic Review
Treatment of Galactosemia
Galactosemia is an inborn disorder of carbohydrate metabolism characterized by the inability to metabolize galactose, a sugar contained in milk (the main source of nourishment for infants), and convert it into glucose, the sugar used by the body as the primary source of energy. Galactosemia is an autosomal recessive genetic disease that can be diagnosed at birth, even in the absence of symptoms, with newborn screening by assessing the level of galactose and the GALT enzyme activity, as GALT defect constitutes the most frequent cause of galactosemia. Currently, galactosemia cannot be cured, but only treated by means of a diet with a reduced content of galactose and lactose. Although the diet is able to reverse the neonatal clinical picture, it does not prevent the development of long-term complications. 
  • 1.5K
  • 29 Jul 2022
Topic Review
Impacts of COVID-19 Pandemic on Public Road Transportation
The COVID-19 pandemic has caused an unprecedented reduction in the demand for public road transportation, and it has changed passengers’ perceptions from positive to negative when it comes to using public transportation amenities. There is an increasing concern that the public road transportation systems are witnessing a new horizon, especially as developed and developing countries are trying to resume their daily activities post the COVID-19 pandemic.
  • 1.5K
  • 22 Sep 2022
  • Page
  • of
  • 2728
Featured Entry Collections
>>

Featured Reprints

>>
Encyclopedia of Digital Society, Industry 5.0 and Smart City
Encyclopedia of Engineering
Encyclopedia of Social Sciences
Encyclopedia of Medieval Royal Iconography
Academic Video Service
Feedback