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Topic Review
Skin Models for Perspiration Simulation
Skin models offer an in vitro alternative to human trials without their high costs, variability, and ethical issues. Perspiration models, in particular, have gained relevance lately due to the rise of sweat analysis and wearable technology.
  • 1.6K
  • 26 Apr 2021
Topic Review
Biomass Combustion in Chile
Chile is a country that is highly dependent on importing energy, particularly fossil hydrocarbons, even though it possesses a variety of energy resources that are relatively well distributed. Around 24% of the country’s power grid comes from forest-based biomass, with firewood being the most-used energy source, mainly for heating and cooking purposes: 97% of firewood is used for heating, and the other 3% is used for domestic water heating and, in some cases, for cooking food. Given that firewood is used by thousands of people during the year, wood burning has had severe social and environmental consequences in densely populated cities such as Temuco. These consequences are mainly due to biomass combustion, which is an important source of particulate matter stemming from the incomplete combustion of components like cellulose, hemicellulose, and lignin, in addition to temperature-produced changes caused by combustion from uncontrolled sources. 
  • 1.6K
  • 06 Jul 2021
Topic Review
Mitochondrial Carriers
Mitochondrial carriers play a fundamental role in cellular metabolism, connecting mitochondrial with cytosolic reactions. By transporting substrates across the inner membrane of mitochondria, they contribute to many processes that are central to cellular function. The genome of Saccharomyces cerevisiae encodes 35 members of the mitochondrial carrier family, most of which have been functionally characterized.
  • 1.6K
  • 23 Sep 2021
Topic Review
Nuclear Envelope
The formation of the nuclear envelope and the subsequent compartmentalization of the genome is a defining feature of eukaryotes. Traditionally, the nuclear envelope was purely viewed as a physical barrier to preserve genetic material in eukaryotic cells.
  • 1.6K
  • 07 Jan 2022
Topic Review
Genetic and Molecular Basis of Von Hippel-Lindau Disease
Von Hippel-Lindau disease (VHL disease or VHL syndrome) is a familial multisystem neoplastic disorder, stemming from germline disease-associated variants of the VHL tumor suppressor gene. VHL protein is involved in oxygen sensing and adaptive response to hypoxia through the EPO-VHL-HIF signaling axis. In recent years, numerous HIF-independent pathways of VHL have been identified, expanding the role of VHL throughout several cellular processes. In addition to VHL syndrome-associated tumors, VHL variations have also been associated with the development of eythrocytosis. Research indicated that there is a distinction between erythrocytosis-causing VHL variations and VHL variations causing VHL disease with tumor development. Therefore, elucidating the molecular background of the pathogenic effects of VHL variants could help determine the best approach to VHL disease management.  
  • 1.6K
  • 24 Mar 2022
Topic Review
Consensual Crime
A consensual crime is a public-order crime that involves more than one participant, all of whom give their consent as willing participants in an activity that is unlawful. Legislative bodies and interest groups sometimes rationalize the criminalization of consensual activity because they feel it offends cultural norms, or because one of the parties to the activity is considered a "victim" despite their informed consent. Consensual crimes can be described as crimes in which the victim is the state, the judicial system, or society at large and so affect the general (sometimes ideological or cultural) interests of the system, such as common sexual morality. Victimless crimes, while similar, typically involve acts that do not involve multiple persons. Drug use is typically considered a victimless crime whereas the sale of drugs between two or more persons would be a consensual crime. The fact that no persons come forward to claim injury has essentially made the two terms interchangeable in common use.
  • 1.6K
  • 14 Oct 2022
Topic Review
Ginger and Breast Cancer
Cancer is one of the leading causes of death in the world, with breast cancer being the most prevalent cancer. Chemotherapy-induced nausea and vomiting (CINV) is one of the most serious side effects of chemotherapy. Because the current CINV treatment option has several flaws, alternative treatment options are required. Ginger has traditionally been used to treat nausea and vomiting, and it also has anticancer properties in breast cancer cells. Based on these findings, researchers investigated whether using ginger to treat CINV in breast cancer patients is both effective and safe.
  • 1.6K
  • 18 Oct 2022
Topic Review
Technologies for Attaining Doubled Haploid Plants In Vivo
Haploid plants with a doubled set of chromosomes (doubled haploid (DH)) significantly speed up the selection process by the fixation of genetic traits in each locus in the homozygous state within one generation. Doubled haploids are mainly attained by the formation of plants from the cultured gametophytic (haploid) tissues and cells in vitro, or by targeted reduction in the parent chromosome during intra- or interspecific hybridization. Since then, DH has become one of the most powerful tools to support various basic research studies, as well as applied research.
  • 1.6K
  • 20 Oct 2022
Topic Review
Asylum Seekers with Apathetic Refugee Children
Asylum seekers with apathetic refugee children was a medical and political debate in Sweden in 2006 concerning asylum seekers who came to Sweden with apathetic children. The period was a subject of media coverage starting in 2002, with 55 cases and in 2005, it escalated to 424 cases. The refugees were mostly from Kazakhstan, Kyrgyzstan, Uzbekistan, Armenia, Azerbaijan, and former Yugoslavia. After a long heated debate, psychiatrist Thomas Jackson, the state investigation expert who held the controversial idea that the children were being abused and should be separated from their parents, was shut out of the debate. The debate ended with a more generous refugee policy that formulated a new condition for the apathetic children titled "resignation syndrome" (uppgivenhetssyndrom in Swedish). Jackson vehemently opposed this diagnosis insisting on calling it coerced child abuse. Jackson also criticized Swedish doctors and the healthcare system for indirectly contributing to child abuse. When suspicions of manipulation or abuse were uncovered, News24 published an article in 2005 of a "child-abuse scam being uncovered in Sweden".
  • 1.6K
  • 27 Oct 2022
Topic Review
Respirator
A respirator is a device designed to protect the wearer from inhaling hazardous atmospheres, including particulate matter such as dusts and airborne microorganisms, as well as hazardous fumes, vapours and gases. There are two main categories: the air-purifying respirator in which respirable air is obtained by filtering a contaminated atmosphere, and the air-supplied respirator in which an alternate supply of breathable air is delivered. Within each category, different techniques are employed to reduce or eliminate noxious airborne contaminants. Air-purifying respirators range from relatively inexpensive single-use, disposable face masks sometimes referred to as a dust mask to more robust reusable models with replaceable cartridges often called a gas mask.
  • 1.6K
  • 01 Dec 2022
Topic Review
Staging Breast Cancer with Magnetic Resonance Imaging
Breast cancer (BC) is the most common cancer among women worldwide and represents one of the leading causes of mortality and morbidity. Neoadjuvant chemotherapy (NACT) is a systemic treatment administered before surgery, whose indications have expanded from inoperable locally advanced to early-stage breast cancer. The pivotal role of magnetic resonance imaging (MRI) with morphological and functional modalities is making headway in the assessment of tumor size in the staging, residual tumor, surgical planning and prediction of response. Radiomics and radiogenomics MRI applications in the setting of breast cancer NACT response prediction are continuously increasing. Tailored systemic therapy strategies allow considerations of treatment de-escalation in excellent responders and avoiding or at least postponing breast surgery in selected patients.
  • 1.6K
  • 15 Dec 2022
Topic Review
Zeolitic Imidazolate Frameworks for CO2 Capture
The requirement to counter carbon emissions is becoming urgent. Zeolitic Imidazolate Frameworks (ZIFs) have been extensively investigated for storing and separating gases, especially carbon dioxide. ZIFs are the subclass of metal-organic frameworks with analogous topology to inorganic porous zeolites. These are attractive candidates for several applications, including storage and separation of gases, due to their outstanding properties such as high CO2 uptake, large surface area, permanent porosity, high thermal stability, high chemical stability, etc.
  • 1.6K
  • 13 Jan 2023
Topic Review
Major Impacts of Potentially Toxic Elements
Environmental contamination with a myriad of potentially toxic elements (PTEs) is triggered by various natural and anthropogenic activities. However, the industrial revolution has increased the intensity of these hazardous elements and their concentration in the environment, which, in turn, could provoke potential ecological risks. Additionally, most PTEs pose a considerable nuisance to human beings and affect soil, aquatic organisms, and even nematodes and microbes. 
  • 1.6K
  • 13 Feb 2023
Topic Review
Heat Exchanger Design Methods
Finned tube heat exchangers are used in many technological applications in both civil and industrial sectors. Their large-scale use requires a design aimed at reaching high thermal efficiency as well as avoiding unnecessary waste of resources in terms of time and costs. Multi-scale methods are very flexible and suitable for different heat exchanger geometries and working conditions because they integrate analytical methods’ benefits with more accurate numerical approaches. The hybrid method is an alternative design procedure based on an algorithm that uses a multi-scale method, based on data from either analytical, numerical, or experimental investigations.
  • 1.6K
  • 12 Apr 2023
Topic Review
Fungal Fuel Cells in Energy Production
Traditional methods have certain limitations and complexities for bioenergy production, which motivates the search for new ways of sustainable bioenergy production and wastewater treatment. Biological strategies have opened new avenues to the treatment of wastewater using oxidoreductase enzymes for the degradation of pollutants. Fungal-based fuel cells (FFCs), with their catalysts, have gained considerable attention among scientists worldwide. They are a new, ecofriendly, and alternative approach to nonchemical methods due to easy handling. FFCs are efficiently used in wastewater treatment and the production of electricity for power generation. 
  • 1.6K
  • 18 Apr 2023
Topic Review
Bouzid Boushaki
Boushaki Boushaki (Thenia, Algeria, April 3, 1935–Thenia, January 23, 2023) (Arabic: بوزيد بوسحاقي) was an Algerian military and politician who participated in the Algerian War of Independence, and was then a trade union leader of the union General Union of Algerian Workers and senior management of Algerian public companies.
  • 1.6K
  • 11 Oct 2023
Topic Review
Qigong
       Owing to work intensification and an accelerated pace of life, individuals in many western countries are often overactivated and find it difficult to switch off. However, recovery from physiological and mental activation is critical to prevent stress symptoms, and maintain one’s physiological and mental well-being. Extensive research evidence indicates that Qigong, a traditional Chinese movement practice for promoting health, provides an effective means to recover from work and off-work demands. The main objective of this entry is to explain Qigong and its core components, and show how Qigong can impact practitioners' fysical and mental health. 
  • 1.6K
  • 19 Nov 2020
Topic Review
Atypical Positional Vertigo
Benign paroxysmal positional vertigo is the most frequent cause of vertigo. As its name indicates, it is characterized by vertigo episodes of sudden onset and end, triggered by changes in head’s position with regard to gravity. It is located in the labyrinth, and its cause is mechanical. However, this is an etiologic diagnosis, reached after questioning and examining the patient. Based on what patients report, the duration of symptoms lasts seconds; however, many overestimate the duration of the vertiginous sensation. The trigger effect of positional changes is a key issue to be addressed. A great variability of autonomic symptoms, including nausea and vomiting, can accompany BPPV. Gait instability, headache, and additional neurologic complaints are potential red flags in the differential diagnosis. With a defined position trigger effect, it is the neurologist’s job to perform an examination to confirm the diagnosis of paroxysmal positional vertigo (PPV), and by virtue of the vertigo duration and nystagmus characteristics, to determine lesion localization (peripheral versus central) and to design a management plan.
  • 1.6K
  • 26 May 2022
Topic Review
Delirium
Delirium is a set of neuropsychiatric symptoms, including qualitative disturbances of consciousness and attention, which may be accompanied by cognitive deficits and psychotic symptoms. The incidence of delirium varies from several percent in patients hospitalized in general wards up to 80% in patients with multi-organ failure treated in intensive care units. Delirium worsens the prognosis, extends hospitalization time, and may increase mortality.
  • 1.6K
  • 27 Aug 2020
Topic Review
Martian Atmospheric Noble Gas Measurements
Martian Atmospheric Noble Gas Measurements refer to technologies to measure Martian atmospheric noble gases in situ by entry probes and in laboratory in Martian meteorites.  
  • 1.6K
  • 02 Dec 2020
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