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Topic Review
Travel sentiment after COVID-19
Tourism and hospitality actors face an unprecedented challenge in reigniting these industries through digital communication. All past knowledge regarding tourist behavior and preferences has been rendered less relevant since the outbreak of the COVID-19 pandemic. These changes result in enforced changes that need to be acknowledged. Several reports have pointed to the existence of a travel sentiment. This travel sentiment integrates the travel intentions and concerns, and trip planning which can be actionable by digital communication.
  • 1.8K
  • 19 Nov 2021
Topic Review
Algae and Fungi: use in Pre-Hispanic Mexico
The use of microorganisms in Mexico began before the Spanish conquest. Grains and fruit were fermented for thousands of years around the world, and Mexico was no exception. Many beverages are still prepared nowadays using an assortment of different microorganisms. These beverages use several yeasts, including Saccharomyces and non-Saccharomyces species. Although not conclusive, it has been suggested (and strong evidence points towards it) that pre-Hispanic cultures not only fermented beverages, but also distilled them.
  • 1.8K
  • 13 Dec 2021
Topic Review
Hydrogen Energy
This entry explains why the 'hydrogen economy' has been so slow in coming, despite the abundance of hydrogen (H2) on Earth. H2 is either bound up with oxygen in water, or with carbon in fossil fuels, which release CO2 on combustion. For several decades, hydrogen-powered vehicles using fuel cells were seen as the major opportunity for H2. But if H2 is produced from fossil fuels, its use makes little contribution to climate change mitigation, and in any case, electric vehicles are now the main challengers to oil for powering transport. H2 will only come into its own when intermittent renewable energy, mainly wind and solar energy, dominate energy supply, as it makes sense to convert surplus power to H2 for storage or immediate use.  
  • 1.8K
  • 04 Jan 2021
Topic Review
From CO2 to Value-Added Products
The global warming and the dangerous climate change arising from the massive emission of CO2 from the burning of fossil fuels have motivated the search for alternative clean and sustainable energy sources. However, the industrial development and population necessities make the decoupling of economic growth from fossil fuels unimaginable and, consequently, the capture and conversion of CO2 to fuels seems to be, nowadays, one of the most promising and attractive solutions in a world with high energy demand. In this respect, the electrochemical CO2 conversion using renewable electricity provides a promising solution. However, faradaic efficiency of common electro-catalysts is low, and therefore, the design of highly selective, energy-efficient, and cost-effective electrocatalysts is critical. Carbon-based materials present some advantages such as relatively low cost and renewability, excellent electrical conductivity, and tunable textural and chemical surface, which show them as competitive materials for the electro-reduction of CO2.
  • 1.8K
  • 23 Mar 2021
Topic Review
Olfaction in Eusocial Ants
Eusocial ants (family Formicidae) engage in a broad range of social behaviors such as nursing the queen’s offspring, foraging for food, and defending their nest. Importantly, these behaviors critically depend on the exchange of information through the detection of chemical cues by a sophisticated olfactory system comprising among the largest number of odorant receptors (ORs) of any insect.
  • 1.8K
  • 05 Jul 2021
Topic Review
Microchromosome Organization in Birds
Interchromosomal rearrangements involving microchromosomes are rare events in birds. To date, they have been found mostly in Neognathae and Neoaves (e.g., Psittaciformes, Falconiformes, and Cuculiformes), although only a few orders have been analyzed. Hence, cytogenomic studies focusing on microchromosomes in species belonging to different bird orders are essential to shed more light on the avian chromosome and karyotype evolution. Relevant hypothetical Neognathae, Neoaves and other ancestral karyotypes can be reconstructed to trace these rearrangements. In a more recent study, a comparative chromosome mapping for chicken microchromosomes 10 to 28 was performed using interspecies BAC-based FISH hybridization in five species, representing four Neoaves orders (Caprimulgiformes, Piciformes, Suliformes, and Trogoniformes). These results suggest that the ancestral microchromosomal syntenies are conserved in Pteroglossus inscriptus (Piciformes), Ramphastos tucanus tucanus (Piciformes), and Trogon surrucura surrucura (Trogoniformes). On the other hand, chromosome reorganization in Phalacrocorax brasilianus (Suliformes) and Hydropsalis torquata (Caprimulgiformes) included fusions involving both macro- and microchromosomes. Fissions in macrochromosomes were observed in P. brasilianus and H. torquata. No interchromosomal rearrangement involving microchromosomes were found to be shared between avian orders where rearrangements were detected. These findings suggest that convergent evolution involving microchromosomal change is a rare event in birds and may be appropriate in cytotaxonomic inferences in orders where these rearrangements occurred.
  • 1.8K
  • 21 Oct 2022
Topic Review
Oscilloscope History
The history of the oscilloscope reaches back to the first recordings of waveforms with a galvanometer coupled to a mechanical drawing system in the second decade of the 19th century. The modern day digital oscilloscope is a consequence of multiple generations of development of the oscillograph, cathode-ray tubes, analog oscilloscopes, and digital electronics.
  • 1.8K
  • 21 Nov 2022
Topic Review
Entropy-Enthalpy Compensations Fold Proteins
 we reveal a protein-folding mechanism based on the entropy-enthalpy compensations that initially driven by laterally hydrophobic collapse among the side-chains of adjacent residues in the sequences of unfolded protein chains. This hydrophobic collapse promotes the formation of the H-bonds within the polypeptide backbone structures through the entropy-enthalpy compensation mechanism, enabling secondary structures and tertiary structures to fold reproducibly following explicit physical folding codes and forces. The temperature dependence of protein folding is thus attributed to the environment dependence of the conformational Gibbs free energy equation. The folding codes and forces in the amino acid sequence that dictate the formation of β-strands and α-helices can be deciphered with great accuracy through evaluation of the hydrophobic interactions among neighboring side-chains of an unfolded polypeptide from a β-strand-like thermodynamic metastable state. The folding of protein quaternary structures is found to be guided by the entropy-enthalpy compensations in between the docking sites of protein subunits according to the Gibbs free energy equation that is verified by bioinformatics analyses of a dozen structures of dimers. Protein folding is therefore guided by multistage entropy-enthalpy compensations of the system of polypeptide chains and water molecules under the solution conditions. 
  • 1.8K
  • 08 Oct 2021
Topic Review
Low-Functioning Autism
Low-functioning autism (LFA) is autism with low functioning levels. Symptoms may include impaired social communications or interactions, bizarre behavior, and lack of social or emotional reciprocity. Sleep problems, aggressiveness, and self-injurious behavior are also possible consequences. LFA is not a recognized diagnosis in the DSM-5 or ICD-10, neither of which subdivides autism based on intellectual capabilities. Synonyms include Kanner's syndrome, Kannerian autism and classic autism. The terms overlap with severe autism and profound autism (as opposed to "mild" or "moderate"), which may be vaguely defined and not necessarily correlate with severe and profound levels of intellectual disability (where profound is the most severe level).
  • 1.8K
  • 27 Oct 2022
Topic Review
Salmonella enterica
Salmonella enterica serovars are important pathogens of humans and animals that are responsible for enormous morbidity, mortality and economic loss worldwide.  Models used to study the disease pathology so far have provided valuable advancements, however, the molecular complexity of its pathogenesis remains poorly understood, particularly in humans. Therefore there remains a disconnect between what works at the bench versus at the bedside, especially in case of vaccines. The development of organoids/enteroids offers a tremendous opportunity to bridge this gap by bringing human-specific factors into the research models as well as elevate our understanding of the interactions and crosstalk between multiple cell types and the microbiota with Salmonella. Thus the use of organoids in studying Salmonella biology has the potential for improving clinical outcomes and future prophylactic and therapeutic intervention strategies.
  • 1.8K
  • 29 Oct 2020
Topic Review
Upcycling of Brewers' Spent Grains
Brewers' spent grains (BSGs) are the most important by-product of the brewing industry and are rich in protein and fiber. However, abundant amounts of BSGs are discarded annually worldwide. This project aimed to employ and compare innovative drying techniques to introduce snacks with protein sources derived from leftover BSGs. This study explored the dehydration kinetics of BSGs and the effect of three different drying methods—oven drying (OD), freeze drying (FD), and vacuum microwave drying (VMD)—on their protein content and functionality. Then, an energy and exergy analysis for the drying methods was given. Accordingly, a snack product (baked chips) using the dehydrated BSGs was developed by a sensory panel study to assess consumer acceptability of the final products. It was found that the VMD process took less drying time (48 min) compared to OD (50 min), with higher effectiveness as a drying process. VMD-treated BSG also showed moderate protein functionality and the highest overall acceptability when used in baked chips. Thus, VMD might be used as a sustainable drying technology for thermal treatment and valorization of BSG. In addition to having implications for dietary health, findings can help improve the economy of the breweries and other industries that deal with the processing of grains by valorizing their process waste and contributing to sustainability.
  • 1.8K
  • 28 Oct 2020
Topic Review
Acute Respiratory Distress Syndrome
The pulmonary endothelium is a metabolically active continuous monolayer of squamous endothelial cells that internally lines blood vessels and mediates key processes involved in lung homoeostasis. Many of these processes are disrupted in acute respiratory distress syndrome (ARDS), which is marked among others by diffuse endothelial injury, intense activation of the coagulation system and increased capillary permeability. Most commonly occurring in the setting of sepsis, ARDS is a devastating illness, associated with increased morbidity and mortality and no effective pharmacological treatment. Endothelial cell damage has an important role in the pathogenesis of ARDS and several biomarkers of endothelial damage have been tested in determining prognosis. By further understanding the endothelial pathobiology, development of endothelial-specific therapeutics might arise. In this review, we will discuss the underlying pathology of endothelial dysfunction leading to ARDS and emerging therapies. Furthermore, we will present a brief overview demonstrating that endotheliopathy is an important feature of hospitalised patients with coronavirus disease-19 (COVID-19).
  • 1.8K
  • 06 Feb 2022
Topic Review
Honokiol
Cancer is characterised by uncontrolled cell division and abnormal cell growth, which is largely caused by a variety of gene mutations. There are continuous efforts being made to develop effective cancer treatments as resistance to current anticancer drugs has been on the rise. Natural products represent a promising source in the search for anticancer treatments as they possess unique chemical structures and combinations of compounds that may be effective against cancer with a minimal toxicity profile or few side effects compared to standard anticancer therapy. Extensive research on natural products has shown that bioactive natural compounds target multiple cellular processes and pathways involved in cancer progression.
  • 1.8K
  • 18 Aug 2021
Topic Review
Interaction-Induced Structural Transformations in Polysaccharide and Protein-Polysaccharide Gels
Polysaccharides are biocompatible nontoxic natural polymer compounds. They are widely used as functional soft-matter for exploration in the food industry, drug delivery, regenerative medicine, and other biomedical research and applications. The tunable macroscopic properties of gels should meet case-dependent requirements. The admixture of proteins to polysaccharides and their coupling in more sophisticated structures opens an avenue for gel property tuning via physical cross-linking of components and the modification of gel network structure.
  • 1.8K
  • 24 May 2022
Topic Review
Metal-Catalyzed Synthesis of the OSe Compounds
Organoselenium (OSe) compounds have recently gained considerable interest as a potential class of organic motifs due to their outstanding applications in synthetic organic and medicinal chemistry and their possible properties in materials science. These are attributed to the exceptional properties of the selenium (Se) element.
  • 1.8K
  • 02 Jun 2022
Topic Review
Factors Affecting SIC Formation in Arid Soils
Soil inorganic carbon (SIC) has received increasing attention due to the high accumulation of SIC in arid soils contributed by its high temperature, low soil moisture, less vegetation, high salinity, and poor microbial activities. SIC storage in dryland soils is a complex process comprising multiple interactions of several factors such as climate, land use types, farm management practices, irrigation, inherent soil properties, soil biotic factors, etc. In addition, soil C studies in deeper layers of drylands have opened-up several study aspects on SIC storage. 
  • 1.8K
  • 27 Sep 2022
Topic Review
Library Anxiety
Library anxiety refers to the "feeling that one’s research skills are inadequate and that those shortcomings should be hidden. In some students this manifests as an outright fear of libraries and the librarians who work there." The term stems from a 1986 article by Constance Mellon, a professor of library science in the United States state of North Carolina, titled "Library anxiety: A grounded theory and its development" in the College & Research Libraries journal.
  • 1.8K
  • 17 Nov 2022
Topic Review
Bispecific Antibody-Based Immune-Cell Engagers in Cancer Immunotherapy
Cancer is the second leading cause of death worldwide after cardiovascular diseases. One of the most promising targeted therapies for cancer treatment is antibody therapy. It has a superior targeting ability for antigens that are expressed on cancer cells, which results in prominent antitumor activity and lower toxicity, compared with that of chemotherapeutic agents. Recent progress in recombinant DNA technology and antibody engineering has ushered in a new era of bispecific antibody (bsAb)-based immune-cell engagers (ICEs), including T- and natural-killer-cell engagers.
  • 1.8K
  • 06 Jan 2023
Topic Review
Challenges Women Experience in Leadership Careers
A part of diversity management is working to achieve gender equality and create a comfortable working environment for women. However, in many organizations, gender biases and stereotypes frequently occur, consciously or unconsciously, regardless of whether women take on leadership roles. In addition, women must overcome a variety of challenges when taking on leadership roles or aspiring to become leaders. Based on the above background, the researchers review and integrate the literature on management and career studies related to the challenges that women face in the process of advancing to leadership positions in organizations. Specifically, the researchers examine the external and internal factors that create the various obstacles that women who aspire to leadership positions in structured organizations face from a gender perspective.
  • 1.8K
  • 24 May 2023
Topic Review
Successful and Emerging Cyberbullying Prevention Programs
The advent of the internet has channeled more online-related tasks into our lives and they have become a pre-requisite. One of the concerns with high internet usage is the multiplication of cyber-associated risky behaviors such as cyber aggression and/or cyberbullying. Cyberbullying is an emerging issue that needs immediate attention from many stakeholders.
  • 1.8K
  • 27 Sep 2023
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