Your browser does not fully support modern features. Please upgrade for a smoother experience.
Subject:
All Disciplines Arts & Humanities Biology & Life Sciences Business & Economics Chemistry & Materials Science Computer Science & Mathematics Engineering Environmental & Earth Sciences Medicine & Pharmacology Physical Sciences Public Health & Healthcare Social Sciences
Sort by:
Most Viewed Latest Alphabetical (A-Z) Alphabetical (Z-A)
Filter:
All Topic Review Biography Peer Reviewed Entry Video Entry
Topic Review
Counterprogramming
In broadcast programming, counterprogramming is the practice of offering television programs to attract an audience from another television station airing a major event. It is also referred when programmers offer something different from the rival’s program as an alternative, to increase the audience size.
  • 1.9K
  • 28 Sep 2022
Topic Review
Taxonomy of Integrated Operation Centers
An Integrated Operation Center (IOC) is essential for efficient Smart Governance. An IOC is a centralized platform that integrates data from various sources and uses advanced analytics to provide real-time insights to help users make informed decisions. It acts as the central nervous system by integrating information and processes from various departments/sources to help officials manage and optimize city operations and infrastructure.
  • 1.9K
  • 04 Aug 2023
Topic Review
MiRNA-Based Therapies in Pulmonary Hypertension
Pulmonary hypertension involves a continuous remodeling of the pulmonary vasculature, that is similar to cancer in some aspects due to the uncontrolled proliferation of certain cells. This leads to muscularization of pulmonary vessels, development of vascular lesions, continuous vasoconstriction, and final heart failure. Current pharmacological therapies only target three molecular pathways and as a result, patients can only improve their life quality but not without suffering adverse side effects. This fatal lung disease lacks effective treatments. Therefore, there are compelling reasons to find new molecular targets and novel therapies that reverse the development of the disease. In this context, miRNA-based therapies have shown promising results that will provided in the following text while explaining the important role that had played their nanoencapsulation.
  • 1.9K
  • 22 Apr 2021
Topic Review
RRM2B-MDS
RRM2B-related mitochondrial DNA depletion syndrome, encephalomyopathic form with renal tubulopathy (RRM2B-MDS) is a severe condition that begins in infancy and affects multiple body systems. It is associated with brain dysfunction combined with muscle weakness (encephalomyopathy). Many affected individuals also have a kidney dysfunction known as renal tubulopathy.
  • 1.9K
  • 04 Jan 2021
Topic Review
Transcutaneous Electrical Nerve Stimulation
Transcutaneous electrical nerve stimulation (TENS) refers to the use of a portable device that generates pulsed electrical currents that are delivered across the intact surface of the skin via conducting electrodes to stimulate peripheral nerves. 
  • 1.9K
  • 25 Apr 2021
Topic Review
Coenzyme Q10: Novel Formulations
Coenzyme Q10 (CoQ10) was first identified back in the fifties by two groups, Festenstein et al. (1955) and Crane et al. (1957). Its name was chosen due to the fact that it is an ubiquitous quinone present in all cells and that its chemical structure comprises a quinone group with a variable number of isoprenyl units, being ten in the case of humans. Its reduced form is known as ubiquinol and the oxidized one as ubiquinone. Both forms coexist and through sequential redox reactions serve to regenerate each other (Q cycle). 
  • 1.9K
  • 14 Jul 2021
Topic Review
Autoimmune Hemolytic Anemia in Chronic Lymphocytic Leukemia
Chronic lymphocytic leukemia (CLL) patients have a greater predisposition to develop autoimmune complications. The most common of them is autoimmune hemolytic anemia (AIHA) with a frequency of 7–10% of cases. Pathogenesis is multifactorial involving humoral, cellular, and innate immunity. 
  • 1.9K
  • 25 Nov 2021
Topic Review
Road Traffic Crashes
Road traffic crashes (RTCs) are a major problem for authorities and governments worldwide. They incur losses of property, human lives, and productivity. 20 to 50 million people are injured in RTCs every year. The involvement of teenage drivers and road users is alarmingly prevalent in RTCs since traffic injuries unduly impact the working-age group (15–44 years). 
  • 1.9K
  • 01 Jul 2022
Topic Review
Francs-Tireurs
Francs-tireurs (pronounced [fʁɑ̃.ti.ʁœʁ], French for "free shooters") were irregular military formations deployed by France during the early stages of the Franco-Prussian War (1870–71). The term was revived and used by partisans to name two major French Resistance movements set up to fight against the Germans during World War II. The term is sometimes used to refer more generally to guerrilla fighters who operate outside the laws of war.
  • 1.9K
  • 02 Nov 2022
Topic Review
Physical Algae Removal Technology
The most commonly used techniques for algae removal by physical methods include mechanical methods, shading technology methods, air flotation, clay flocculation, ultrasonic methods, filtration, ultraviolet irradiation, and adsorption.
  • 1.9K
  • 21 Mar 2023
Topic Review
Wingtip Vortices: An Extensive Review
Wingtip vortices generated from aircraft wingtips, as a result of the pressure differential at the wingtip, constitute a major component of the total drag force, especially during take-off and landing. In addition to the drag issue, these vortices also pose a significant hazard to smaller aircraft flying in the wake of the larger airplane. The wingtip vortices play a crucial role in aerodynamic efficiency, fuel consumption, flight range, and aircraft stability. 
  • 1.9K
  • 25 Jan 2024
Topic Review
Caesarean Section
Cesarean section is a surgical procedure, which is the most frequently performed in gynecology and obstetrics. It is commonly believed that an operative delivery is a less painful and safer mode of delivery, which translates into an increasing number of the procedures performed without medical indications. The maternal sequelae of cesarean sections are well elucidated and widely discussed in the literature, while long-term neonatal consequences still remain the issue of research and scientific dispute.
  • 1.9K
  • 24 Sep 2021
Topic Review
Plant-Based Indole Alkaloids
Indole (C8H7N) is a weakly basic molecule consisting of a pyrrole ring fused to a benzene nucleus, and ten π electrons move throughout the structure. The basic environment of indole alkaloids is thought to be caused by the delocalization of the lone pair of nitrogen electrons into the free circulation of the π electronic system. This results in indole becoming protonated at the C-3 position, which is thermodynamically more stable.Indole alkaloids have gained popularity due to their diverse pharmacological activities. Indole alkaloids have been identified in several prominent plant families, including Apocynaceae, Rubiaceae, Nyssaceae, and Loganiaceae, among others. Some of the identified indole alkaloid compounds have been highly effective in pre-clinical and clinical studies. Thousands of compounds containing the indole nucleus have been isolated from plant sources. Their pharmacological activities were assessed, with some now being examined in clinical trials and some already approved for therapeutic use in humans. Indole alkaloids are often characterized by their potent biological activities, which are relevant to the field of medicine, including anticancer, antibacterial, antiviral, antimalarial, antifungal, anti-inflammatory, antidepressant, analgesic, hypotensive, anticholinesterase, antiplatelet, antidiarrheal, spasmolytic, antileishmanial, lipid-lowering, antimycobacterial, and antidiabetic activities. 
  • 1.9K
  • 27 Apr 2021
Topic Review
Mechanism of Parkinson’s Disease Drugs
Parkinson’s Disease (PD) is a progressive degenerative neurological disorder commonly presenting with symptoms of muscle rigidity, instability, tremor, bradykinesia (slow in movement), and lack of coordination. There are conventional drugs used in treating Parkinson’s disease such as levodopa, dopamine agonists, anticholinergics, catechol-O-methyltransferase (COMT) inhibitors, monoamine oxidase-B (MAO-B) inhibitors, and amantadine. Other drugs used in treating PD related psychosis include antipsychotics. 
  • 1.9K
  • 07 Mar 2022
Biography
Susan Kilrain
Susan Kilrain (born October 24, 1961) is an engineer, a former United States Navy officer, and a former NASA astronaut. Kilrain was born in Augusta, Georgia, as Susan Leigh Still to Dr. Joseph Still, M.D. and his wife, Jean Ann Batho; she has nine siblings. Her father was a prominent burn surgeon who founded and directed the Joseph M. Still Burn Center in Augusta, Georgia. Kilrain graduated f
  • 1.9K
  • 02 Dec 2022
Topic Review
Poly(Ionic Liquid) Materials-Based Advanced Formulations for Additive Manufacturing
Innovation in materials specially formulated for additive manufacturing is of great interest and can generate new opportunities for designing cost-effective smart materials for next-generation devices and engineering applications. Nevertheless, advanced molecular and nanostructured systems are frequently not possible to integrate into 3D printable materials, thus limiting their technological transferability. In some cases, this challenge can be overcome using polymeric macromolecules of ionic nature, such as polymeric ionic liquids (PILs). Due to their tuneability, wide variety in molecular composition, and macromolecular architecture, they show a remarkable ability to stabilize molecular and nanostructured materials. The technology resulting from 3D-printable PIL-based formulations represents an untapped array of potential applications, including optoelectronic, antimicrobial, catalysis, photoactive, conductive, and redox applications.
  • 1.9K
  • 08 Dec 2022
Topic Review
Adversarial Machine Learning Attacks against Intrusion Detection Systems
Concerns about cybersecurity and attack methods have risen in the information age. Many techniques are used to detect or deter attacks, such as intrusion detection systems (IDSs), that help achieve security goals, such as detecting malicious attacks before they enter the system and classifying them as malicious activities. However, the IDS approaches have shortcomings in misclassifying novel attacks or adapting to emerging environments, affecting their accuracy and increasing false alarms. To solve this problem, researchers have recommended using machine learning approaches as engines for IDSs to increase their efficacy. Machine-learning techniques are supposed to automatically detect the main distinctions between normal and malicious data, even novel attacks, with high accuracy. However, carefully designed adversarial input perturbations during the training or testing phases can significantly affect their predictions and classifications. Adversarial machine learning (AML) poses many cybersecurity threats in numerous sectors that use machine-learning-based classification systems, such as deceiving IDS to misclassify network packets.
  • 1.9K
  • 09 Mar 2023
Topic Review
Urban Archetypes
To make cities more sustainable and livable and to achieve climate targets in transportation, cities around the globe must undergo sustainable transformations. However, disparities in initial conditions pose challenges when trying to implement these sustainable changes. Identifying these differences aids in the comprehension of future developments. Urban archetypes represent a typification of cities in order to investigate mobility-related homogeneity between cities.
  • 1.9K
  • 27 Nov 2023
Topic Review
Sphingosine Kinase 1
Sphingosine kinase (SPHK) catalyses the ATP-dependent phosphorylation of sphingosine to form sphingosine 1-phosphate (S1P), which acts as an intracellular second messenger and extracellular ligand for specific receptors. S1P can be released through specific transporters to act as a ligand for the family of G protein-coupled S1P receptors 1 to 5 (S1P1 to S1P5) and regulates a wide range of biological effects including transformation and cancer cell survival. S1P levels are tightly regulated by the balance between synthesis by SPHK, reversible conversion to sphingosine by specific S1P phosphatases (SPP1 and SPP2), and degradation by S1P lyase. 
  • 1.9K
  • 27 Oct 2020
Topic Review
High Performance Bioplastics
Biomass provides a wealth of renewable and bio-waste resources for bioplastics synthesis. Many of these bio-based plastics, encompass capacities for biodegradation and bioprocessing with high performance features akin to petroleum-based plastics. The realisation of bioplastics that exhibit a complete set of mechanical and biodegradability, hold the promise of delivering material of ecologically sustainable, low carbon footprint circularity.
  • 1.9K
  • 14 Jul 2021
  • Page
  • of
  • 2799
Featured Entry Collections
>>

Featured Reprints

>>
Encyclopedia of Digital Society, Industry 5.0 and Smart City
Encyclopedia of Engineering
Encyclopedia of Social Sciences
Encyclopedia of Medieval Royal Iconography
Academic Video Service
Feedback