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Topic Review
Neoadjuvant Chemotherapy in Breast Cancer
Neoadjuvant chemotherapy is increasingly being employed in the management of breast cancer patients. To ensure that health care needs are adequately addressed, clinicians must consider that women with breast cancer have a high risk of developing “unmet needs” during treatment, and often require a clinical intervention or additional care resources to limit possible complications and psychological issues that can occur during neoadjuvant treatment.
  • 2.1K
  • 27 May 2021
Topic Review
List of Intel Itanium Microprocessors
The Itanium from Intel is a high-end server and supercomputer microprocessor.
  • 2.1K
  • 28 Oct 2022
Topic Review
Circular RNAs in Metastasis in Breast Cancer
Circular RNAs (circRNAs) are single-stranded closed non-coding RNA molecules that are aberrantly expressed and produce tumor-specific gene signatures in human cancers. They exert biological functions by acting as transcriptional regulators, microRNA sponges, and protein scaffolds, regulating the formation of protein–RNA complexes and, ultimately, regulating gene expression. Triple-negative breast cancer (TNBC) is one of the most aggressive cancers of the mammary gland and has a poor prognosis. Studies of circRNAs in TNBC are limited but have demonstrated these molecules’ pivotal roles in cell proliferation, invasion, metastasis, and resistance to chemo/radiotherapy, suggesting that they could be potential prognostic biomarkers and novel therapeutic targets. 
  • 2.1K
  • 20 Nov 2023
Topic Review
The Pathology of Parkinson’s Disease
Parkinson’s disease (PD) is a progressive neurodegenerative disorder that is characterized by a loss of dopaminergic neurons, leading to bradykinesia, rigidity, tremor at rest, and postural instability, as well as non-motor symptoms such as olfactory impairment, pain, autonomic dysfunction, impaired sleep, fatigue, and behavioral changes. 
  • 2.1K
  • 23 Feb 2021
Topic Review
Thin-Film Fabrication for Low-Temperature Solid Oxide Fuel Cells
Solid oxide fuel cells (SOFCs) are amongst the most widely used renewable alternative energy systems with near-zero carbon emission, high efficiency, and environment-friendly features. However, the high operating temperature of SOFCs is still considered a major challenge due to several issues regarding the materials’ corrosion, unwanted reactions between layers, etc. Thus, low-temperature SOFCs (LT-SOFCs) have gained significant interest during the past decades. Despite the numerous advantages of LT-SOFCs, material selection for each layer is of great importance as the common materials have not shown a desirable performance so far. In addition to the selection of the materials, fabrication techniques have a great influence on the properties of the SOFCs. As SOFCs with thinner layers showed lower polarisation resistance, especially in the electrolyte layer, different thin-film fabrication methods have been employed, and their effect on the overall performance of SOFCs has been evaluated.
  • 2.1K
  • 23 Aug 2023
Topic Review
Neuroarchaeology
Neuroarchaeology refers to a field of study that records neuroscientific history through archaeological methods of investigation. The term was first suggested and thus coined by Colin Renfrew and Lambros Malafouris first individually in 2004 and then collaboratively in 2008.It is a combination of the words "neuro-" from 'neuroscience' indicating its connection with the brain sciences and "archaeology" meaning study of human history and prehistory through excavations and other tools. Significant leaps in brain and cognitive sciences in the 21st century have opened up new areas of partnership between archaeology and neuroscience. This collaboration can help an archaeologist figure out biological and neural substrates of human cognitive abilities present in the archaeological objects. The knowledge of neuroscience can also be applied to critically review and challenge existing theories and assumptions about the inception of modern human cognition. The term implies a new area of research that could investigate issues relating to the collaboration between the brain and culture over the long term development of humans. So far, the goals of neuroscience and archaeology are the same- to understand human nature. But their disciplinary approaches diverge significantly. Neuroarchaeology aims at building the analytical bridge between brain and culture ""by putting material culture, embodiment, time and long-term change at centre stage in mind".
  • 2.1K
  • 21 Nov 2022
Topic Review
Homophile
The words homophile and homophilia are dated terms for homosexuality. The use of the word began to disappear with the emergence of the gay liberation movement of the late 1960s and early 1970s, replaced by a new set of terminology such as gay, lesbian, and bisexual.
  • 2.1K
  • 21 Nov 2022
Topic Review
Gynecological Problems in Newborns
Pediatric-adolescent or developmental gynecology has been separated from the general gynecology because of the unique issues that affect the development and anatomy of growing girls and young women. It deals with patients from the neonatal period until maturity. There are not many gynecological problems that can be diagnosed in newborns; however, some are typical for the neonatal period. This paper aimed to discuss the most frequent gynecological issues in the neonatal period.
  • 2.1K
  • 12 Mar 2021
Topic Review
Protein–Polysaccharide Complexes (Conjugates) as Delivery Systems
Due to their combination of featured properties, protein and polysaccharide-based carriers show promising potential in food bioactive ingredient encapsulation, protection, and delivery. The common types of protein–polysaccharide complex/conjugate-based bioactive ingredient delivery systems include emulsion (conventional emulsion, nanoemulsion, multiple emulsion, multilayered emulsion, and Pickering emulsion), microcapsule, hydrogel, and nanoparticle-based delivery systems. This entry highlights the applications of protein–polysaccharide-based delivery vehicles in common bioactive ingredients including polyphenols, food proteins, bioactive peptides, carotenoids, vitamins, and minerals. The loaded food bioactive ingredients exhibited enhanced physicochemical stability, bioaccessibility, and sustained release in simulated gastrointestinal digestion. 
  • 2.1K
  • 04 Mar 2022
Topic Review
Racing Thoughts
Racing thoughts refers to the rapid thought patterns that often occur in manic, hypomanic, or mixed episodes. While racing thoughts are most commonly described in people with bipolar disorder and sleep apnea, they are also common with anxiety disorders, OCD, and other psychiatric disorders such as attention deficit hyperactivity disorder. Racing thoughts are also associated with sleep deprivation, hyperthyroidism. and the use of amphetamines.
  • 2.1K
  • 10 Oct 2022
Topic Review
Stable Gastric Pentadecapeptide BPC 157
Stable gastric pentadecapeptide BPC 157 especial therapy effects combine the therapy of myocardial infarction, heart failure, pulmonary hypertension arrhythmias, and thrombosis prevention and reversal. The shared therapy effect occurred as part of its even larger cytoprotection (cardioprotection) therapy effect (direct epithelial cell protection; direct endothelium cell protection) that BPC 157 exerts as a novel cytoprotection mediator, which is native and stable in human gastric juice, as well as easily applicable.
  • 2.1K
  • 07 Nov 2022
Topic Review
Outline of Ubuntu
The following outline is provided as an overview of and topical guide to Ubuntu: Ubuntu — Debian-based Linux operating system for personal computers, tablets and smartphones, where Ubuntu Touch edition is used; and also runs network servers, usually with the Ubuntu Server edition, either on physical or virtual servers (such as on mainframes) or with containers, that is with enterprise-class features; runs on the most popular architectures, including server-class ARM-based. Ubuntu is published by Canonical Ltd., who offer commercial support.
  • 2.1K
  • 10 Nov 2022
Topic Review
Dysregulation of Microbiome–Immunity Interaction in Various Diseases
Gut microbes and their metabolites are actively involved in the development and regulation of host immunity, which can influence disease susceptibility. The role of the microbiome as a protective force is supported by research indicating that immature microbiomes of neonates are more susceptible to invasion by pathobionts. During early years of development, exposure to various microbes shapes the immune system for a lifetime. The gut microbiome has a wide range of metabolic activities, including metabolizing lipids, carbohydrates, and proteins, and participates in maintaining host homeostasis. Therefore, disruption of gut microbiome can lead to conditions as severe as cancer.
  • 2.1K
  • 06 Feb 2023
Topic Review
Deep Learning for Robotic Vision Methods
Robotic vision algorithms serve three primary functions in visual perception. Pattern recognition in machine vision is the process of identifying and classifying objects or patterns in images or videos using machine learning algorithms. Deep learning in robotic vision reveals a plethora of promising approaches, each with its own unique strengths and characteristics. Robotic vision systems can leverage the strengths of each architecture to improve object detection, tracking, and the understanding of complex visual scenes in dynamic environments. Big data and federated learning play significant roles in advancing the field of computer vision. Big data provides a wealth of diverse visual information, which is essential for training deep learning models that power computer vision applications. These datasets enable more accurate object recognition, image segmentation, and scene understanding.
  • 2.1K
  • 07 Feb 2024
Topic Review
Single Board Architectures Integrating Sensors Technologies
Development boards, Single-Board Computers (SBCs) and Single-Board Microcontrollers (SBMs) integrating sensors and communication technologies have become a very popular and interesting solution in the last decade. They are of interest for their simplicity, versatility, adaptability, ease of use and prototyping, which allow them to serve as a starting point for projects and as reference for all kinds of designs.
  • 2.1K
  • 11 Oct 2021
Topic Review
Implementing Sustainable Irrigation
      The sustainability of irrigated agriculture is threatening due to adverse climate change, given future projections that every one in four people on Earth might be suffering from extreme water scarcity by the year 2025. Pressurized irrigation systems and appropriate irrigation schedules can increase water productivity (i.e., product yield per unit volume of water consumed by the crop) and reduce the evaporative or system loss of water as opposed to traditional surface irrigation methods. However, in water-scarce countries, irrigation management frequently becomes a complex task. Deficit irrigation and the use of non-conventional water resources (e.g., wastewater, brackish groundwater) has been adopted in many cases as part of a climate change mitigation measures to tackle the water poverty issue. Protected cultivation systems such as greenhouses or screenhouses equipped with artificial intelligence systems present another sustainable option for improving water productivity and may help to alleviate water scarcity in these countries. This article presents a comprehensive review of the literature, which deals with sustainable irrigation for open-field and protected cultivation systems under the impact of climatic change in vulnerable areas, including the Mediterranean region.
  • 2.1K
  • 27 Apr 2023
Topic Review
Flower Strips
Wildflower strips, a semi-natural manmade habitat comprising mixtures of native herbaceous species, can be sown on arable field margins to provide multiple ecological, agricultural and conservation benefits. The main aim of creating flower strips is to enrich the fauna of farmland with the species that are beneficial in terms of the agricultural economy: animals that limit the population density of pests (e.g., parasitic insects, including parasitoids, predatory insects and spiders and birds) and pollinators (insects that feed on pollen or nectar), including those with economic significance. For this reason, flower strips should be included in agri-environmental programs to enhance sustainable plant production and the biodiversity of pollinators on farmland or natural aphid enemies. Flower strips are thus increasingly frequently promoted in environmental programmes, and financial support is being implemented as an additional business incentive.
  • 2.1K
  • 08 Oct 2022
Topic Review
Squalene and Cardiovascular Health
Squalene (SQ), an unsaturated hydrocarbon naturally synthesized in plants and animals, could become the alternative treatment or supplementary agent for cardiovascular health.
  • 2.1K
  • 26 Feb 2021
Topic Review
Oral Cancer and Diet
Oral cancer, included within head and neck cancer, is the sixth most common malignant neoplasm in the world. The main etiological factors are tobacco and alcohol, although currently, diet is considered an important determinant for its development. Several dietary nutrients have specific mechanisms of action, contributing to both protection against cancer and increasing the risk for development, growth, and spread. Foods such as fruits, vegetables, curcumin, and green tea can reduce the risk of oral cancer, while the so-called pro-inflammatory diet, rich in red meat and fried foods, can enhance the risk of occurrence. Dietary factors with a protective effect show different mechanisms that complement and overlap with antioxidant, anti-inflammatory, anti-angiogenic, and anti-proliferative effects. 
  • 2.1K
  • 29 Apr 2021
Topic Review
Cognition-Based Evolution
Cognition-Based Evolution (CBE) asserts a comprehensive alternative approach to phenotypic variation and the generation of biological novelty. In CBE, evolutionary variation is the product of natural cellular engineering that permits purposive genetic adjustments as cellular problem-solving. CBE upholds that the cornerstone of biology is the intelligent measuring cell. Since all biological information that is available to cells is ambiguous, multicellularity arises from the cellular requirement to maximize the validity of available environmental information. This is best accomplished through collective measurement purposed towards maintaining and optimizing individual cellular states of homeorhesis as dynamic flux that sustains cellular equipoise. The collective action of the multicellular measurement and assessment of information and its collaborative communication is natural cellular engineering. Its yield is linked cellular ecologies and mutualized niche constructions that comprise biofilms and holobionts. In this context, biological variation is the product of collective differential assessment of ambiguous environmental cues by networking intelligent cells. Such concerted action is enabled by non-random natural genomic editing in response to epigenetic impacts and environmental stresses. Random genetic activity can be either constrained or deployed as a ‘harnessing of stochasticity’. Therefore, genes are cellular tools. Selection filters cellular solutions to environmental stresses to assure continuous cellular-organismal-environmental complementarity. Since all multicellular eukaryotes are holobionts as vast assemblages of participants of each of the three cellular domains (Prokaryota, Archaea, Eukaryota) and the virome, multicellular variation is necessarily a product of co-engineering among them. 
  • 2.1K
  • 20 May 2021
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