Your browser does not fully support modern features. Please upgrade for a smoother experience.
Subject:
All Disciplines Arts & Humanities Biology & Life Sciences Business & Economics Chemistry & Materials Science Computer Science & Mathematics Engineering Environmental & Earth Sciences Medicine & Pharmacology Physical Sciences Public Health & Healthcare Social Sciences
Sort by:
Most Viewed Latest Alphabetical (A-Z) Alphabetical (Z-A)
Filter:
All Topic Review Biography Peer Reviewed Entry Video Entry
Topic Review
Mitochondrial Dysfunction
Mitochondrial dysfunction results in a series of defective cellular events, including decreased adenosine triphosphate (ATP) production, enhanced reactive oxygen species (ROS) output, and altered proteastasis and cellular quality control. An enhanced output of ROS may damage mitochondrial components, such as mitochondrial DNA and elements of the electron transport chain, resulting in the loss of proper electrochemical gradient across the mitochondrial inner membrane and an ensuing shutdown of mitochondrial energy production. Neurons have an increased demand for ATP and oxygen, and thus are more prone to damage induced by mitochondrial dysfunction. Mitochondrial dysfunction, damaged electron transport chains, altered membrane permeability and Ca2+ homeostasis, and impaired mitochondrial defense systems induced by oxidative stress, are pathological changes involved in neurodegenerative disorders. A growing body of evidence suggests that the use of antioxidants could stabilize mitochondria and thus may be suitable for preventing neuronal loss. Numerous natural products exhibit the potential to counter oxidative stress and mitochondrial dysfunction; however, science is still looking for a breakthrough in the treatment of neurodegenerative disorders. β-caryophyllene is a bicyclic sesquiterpene, and an active principle of essential oils derived from a large number of spices and food plants. As a selective cannabinoid receptor 2 (CB2) agonist, several studies have reported it as possessing numerous pharmacological activities such as antibacterial (e.g., Helicobacter pylori), antioxidant, anti-inflammatory, analgesic (e.g., neuropathic pain), anti-neurodegenerative and anticancer properties. The present review mainly focuses on the potential of β-caryophyllene in reducing oxidative stress and mitochondrial dysfunction, and its possible links with neuroprotection. 
  • 2.2K
  • 29 Apr 2021
Topic Review
Building Design for Preventing COVID-19 Pandemic
Sustainable design methods aim to obtain architectural solutions that assure the coexistence and welfare of human beings, inorganic structures, and living things that constitute ecosystems. The novel coronavirus emergence, inadequate vaccines against the present severe acute respiratory syndrome-coronavirus-(SARS-CoV-2), and increases in microbial resistance have made it essential to review the preventative approaches used during pre-antibiotic periods. Apart from low carbon emissions and energy, sustainable architecture for facilities, building designs, and digital modeling should incorporate design approaches to confront the impacts of communicable infections. This review aims to determine how architectural design can protect people and employees from harm; it models viewpoints to highlight the architects’ roles in combating coronavirus disease 2019 (COVID-19) and designing guidelines as a biomedical system for policymakers. The goals include exploring the hospital architecture evolution and the connection between architectural space and communicable infections and recommending design and digital modeling strategies to improve infection prevention and controls. Based on a wide-ranging literature review, it was found that design methods have often played important roles in the prevention and control of infectious diseases and could be a solution for combating the wide spread of the novel coronavirus or coronavirus variants or delta. 
  • 2.2K
  • 24 May 2022
Biography
Yuko Tojo
Yuko Tojo (東條 由布子, Tōjō Yūko, May 20, 1939 (Keijo, Japanese Korea) – February 13, 2013, Tokyo, Japan) was a Japanese ultra-nationalist politician, Imperial Japanese apologist, and brief political hopeful.[1] She was the granddaughter of General Hideki Tōjō, the Japanese wartime prime minister who was convicted of planning and orchestrating most of the major Japanese acts of aggr
  • 2.2K
  • 20 Dec 2022
Topic Review
Tool Wear Suppression Methods of Diamond-cutting Ferrous Metals
This entry introduces some common tool wear suppression methods of diamond-cutting ferrous metals.
  • 2.2K
  • 30 Oct 2020
Topic Review
Probiotics in Poultry Nutrition
Probiotics are live bacteria, fungi, or yeasts that supplement the gastrointestinal flora and help to maintain a healthy digestive system, thereby promoting the growth performance and overall health of poultry.
  • 2.2K
  • 06 Nov 2020
Topic Review
Methods of Preparation of UHMWPE Membranes
One of the materials that attracts attention as a potential material for membrane formation is ultrahigh molecular weight polyethylene (UHMWPE). The methods used to prepare membranes from semicrystalline (SC) polymers, including UHMWPE, can be divided into two main groups: solvent-free and solvent-based methods.
  • 2.2K
  • 30 Nov 2022
Topic Review
Composting
Composting is the most adaptable and fruitful method for managing biodegradable solid wastes; it is a crucial agricultural practice that contributes to recycling farm and agricultural wastes. Composting is profitable for various plant, animal, and synthetic wastes, from residential bins to large corporations. Composting and agricultural waste management (AWM) practices flourish in developing countries, especially Pakistan.
  • 2.2K
  • 16 Mar 2023
Topic Review
Spherical Nanoparticles
An up-to-date overview of the current state of the art of polysaccharide-based spherical particles as carriers of active/bioactive substances, with a particular emphasis on their applications in the food industry, is provided. Owing to the rapid advances in nanotechnology, much effort has been dedicated to the synthesis and potential uses of these particles.
  • 2.2K
  • 03 Nov 2023
Topic Review
Mechanisms of Light-Triggered Drug Release from Liposomes
Light-triggered mechanisms that can be exploited to release encapsulated drugs from liposomes are photoisomerization, photocleavage (photo-oxidation), surface plasmon resonance absorption (photothermal activation), photochemical hydrophobicity change (photochemical activation), and photo-crosslinking and de-crosslinking.
  • 2.2K
  • 18 Feb 2024
Topic Review
Glutamine in brain cancer metabolism
Glutamine is a non-essential amino acid that plays a key role in the metabolism of proliferating cells including neoplastic cells. In the central nervous system (CNS), glutamine metabolism is particularly relevant, because the glutamine–glutamate cycle is a way of controlling the production of glutamate-derived neurotransmitters by tightly regulating the bioavailability of the amino acids in a neuron-astrocyte metabolic symbiosis-dependent manner. Glutamine-related metabolic adjustments have been reported in several CNS malignancies including malignant gliomas that are considered ‘glutamine addicted’. In these tumors, glutamine becomes an essential amino acid preferentially used in energy and biomass production including glutathione (GSH) generation, which is crucial in oxidative stress control. Therefore, in this review, we will highlight the metabolic remodeling that gliomas undergo, focusing on glutamine metabolism. We will address some therapeutic regimens including novel research attempts to target glutamine metabolism and a brief update of diagnosis strategies that take advantage of this altered profile. A better understanding of malignant glioma cell metabolism will help in the identification of new molecular targets and the design of new therapies.
  • 2.2K
  • 26 Oct 2020
Topic Review
Academic Journals
Many academics are critical of the current publishing system, but it is difficult to create a better alternative. The perspective relates to the sciences and social sciences, and discusses the primary purpose of academic journals as providing a seal of approval for perceived quality, impact, significance, and importance. The key issues considered include the role of anonymous refereeing, continuous rather than discrete frequency of publications, avoidance of time wasting, and seeking adventure. Here we give recommendations about the organization of journal articles, the roles of associate editors and referees, measuring the time frame for refereeing submitted articles in days and weeks rather than months and years, encouraging open access internet publishing, emphasizing the continuity of publishing online, academic publishing as a continuous dynamic process, and how to improve research after publication. Citations and functions thereof, such as the journal impact factor and h-index are the benchmark for evaluating the importance and impact of academic journals and published articles. Even in the very top journals, a high proportion of published articles is never cited, not even by the authors themselves. Top journal publications do not guarantee that published articles will make significant contributions, or that they will ever be highly cited. The COVID-19 world should encourage academics worldwide not only to rethink academic teaching, but also to re-evaluate key issues associated with academic journal publishing in the future.   
  • 2.2K
  • 13 Apr 2021
Topic Review
ADP-Ribosyltransferase Toxin
ADP-ribosyltransferases (ARTs) are a well-known type of bacterial toxin. They transfer an ADP-ribose moiety from nicotinamide adenine dinucleotide (NAD+) onto a target protein to generate an ADP-ribosylated protein and nicotinamide. The bulky and negatively charged ADP-ribose moiety affects the protein function by sterically blocking interactions with partner molecules, inducing conformational changes, or creating docking sites for new interaction partners.
  • 2.2K
  • 25 Jan 2021
Topic Review
Ti-Based Catalysts on Magnesium Hydride
Magnesium-based hydrides are considered as promising candidates for solid-state hydrogen storage and thermal energy storage, due to their high hydrogen capacity, reversibility, and elemental abundance of Mg. To improve the sluggish kinetics of MgH2, catalytic doping using Ti-based catalysts is regarded as an effective approach to enhance Mg-based materials.
  • 2.2K
  • 31 May 2021
Topic Review
β-butyrolactone
Over 35 years ago, researchers originally reported on the anionic ring-opening polymerization (ROP) of β-butyrolactone (BBL) into poly(β-butyrolactone) (poly(BBL)), which is an amorphous, atactic analogue of isotactic poly([R]-β-hydroxybutyrate) (PHB), a promising and widely used natural biodegradable polyester. 
  • 2.2K
  • 30 Dec 2021
Topic Review
Homi
Homi (Korean: 호미), also known as a Korean hand plow, is a short-handled traditional farming tool used by Koreans. It is a farming tool that removes grasses from paddies and fields. It is also used when plowing a rice field, planting seeds, plowing up soil, and digging potatoes in fields. It is a farming tool similar to the hoe. It is an important extension of agriculture from the ancient times because the homi was excavated in the Bronze Age historic site of the Pyeongnam Mangsan Daepyeong-ri and the early Iron Age historic site of Yangpyong, Gyeonggi Province. Homi is distributed nationwide, but they are characterized by locality. In other words, homi is classified into Plowshare-shaped(보습형), Sickle-shaped(낫형), and Triangle-shaped(세모형) depending on the natural conditions of the local area and the characteristics of agricultural management.
  • 2.2K
  • 26 Oct 2022
Topic Review
Hydrogen Sulfide Corrosion in Oil and Gas Industries
In the oil and gas industry, the corrosion attributed to hydrogen sulfide (H2S) is one of the most significant challenges.
  • 2.2K
  • 26 Feb 2024
Topic Review
Triploid Fish
Over the past decades, evidence is emerging that triploid fish exhibit interesting genetic, anatomical, cellular and biochemical peculiarities with potential growth advantages for the Aquaculture industry are including economic gains and improved feed conversion rate. A review of the current literature indicates that an assessment of the possible advantages and disadvantages of farming triploid sea bass should include the effects of ploidy on flesh quality parameters and in the capacity for aerobic and anaerobic metabolism at different seasonal temperatures. 
  • 2.2K
  • 05 Nov 2020
Topic Review
Additive Manufacturing
Additive manufacturing, which is also known as 3D printing, is an emerging and growing technology. It is providing significant innovations and improvements in many areas such as engineering, production, medicine, and more. 3D food printing is an area of great promise to provide an indulgence or entertaining experience, personalized food product, or specific nutritional needs. This entry reviews the additive manufacturing methods and materials in detail as well as their advantages and disadvantages. After a full discussion of 3D food printing, the reports on edible printed materials are briefly presented and discussed. In the end, the current and future outlook of additive manufacturing in the food industry is shown.
  • 2.2K
  • 09 Apr 2021
Topic Review
Microplastics in Ecosystems
Plastics are widely used due to their excellent properties, inexpensiveness and versatility leading to an exponential consumption growth during the last decades. However, most plastic does not biodegrade in any meaningful sense; it can exist for hundreds of years. Only a small percentage of plastic waste is recycled, the rest being dumped in landfills, incinerated or simply not collected. Microplastics can be generally divided in two big families: primary microplastics and secondary microplastics. Plastics with microscopic size, ca. 2–5 mm in diameter, are defined as primary microplastics. Secondary microplastics enclose tiny plastic fragments derived from the breakdown of larger plastic debris, both at sea and on land. Waste-water treatment plants can only minimize the problem by trapping plastic particles of larger size and some smaller ones remain within oxidation ponds or sewage sludge, but a large amount of microplastics still contaminate water streams and marine systems. 
  • 2.2K
  • 23 Jan 2021
Topic Review
Palladium-Catalyzed Carboxylation Reactions
The efficient incorporation of carbon dioxide into an organic substrate (carboxylation) under catalytic conditions to give high value added molecules is one of the most important and fascinating areas of current organic synthesis. Carbon dioxide is a nonflammable, inexpensive and largely available C-1 feedstock. In fact, it allows converting an important waste (it is well known that carbon dioxide is produced in enormous amounts from the combustion of fossil fuels for the production of energy) into a variety of useful compounds, which can find application as fuels or in the pharmaceutical or material fields.
  • 2.2K
  • 06 Jan 2022
  • Page
  • of
  • 2799
Featured Entry Collections
>>

Featured Reprints

>>
Encyclopedia of Digital Society, Industry 5.0 and Smart City
Encyclopedia of Engineering
Encyclopedia of Social Sciences
Encyclopedia of Medieval Royal Iconography
Academic Video Service
Feedback