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Topic Review
Neuropeptides in Anxiety and Depression
In modern society, there has been a rising trend of depression and anxiety. This trend heavily impacts the population’s mental health and thus contributes significantly to morbidity and, in the worst case, to suicides. Modern medicine, with many antidepressants and anxiolytics at hand, is still unable to achieve remission in many patients. The pathophysiology of depression and anxiety is still only marginally understood, which encouraged researchers to focus on neuropeptides, as they are a vast group of signaling molecules in the nervous system. Neuropeptides are involved in the regulation of many physiological functions
  • 2.2K
  • 13 Sep 2022
Topic Review
Plant-Based Meat Analogues from Alternative Protein
Meat is a major source of dietary protein. It is frequently recognized as a high-quality protein source due to its nutritional qualities and favorable sensory properties such as texture and flavor. However, a rising global population has led to a rise in the production and consumption of meat around the world, which has raised environmental concerns regarding the usage of land and water, as well as the impact of pollution and climate change, greenhouse gas emissions, and the loss of biodiversity. Plant proteins seem to be a possible solution to these issues since they can replace meat through the creation of nutritionally and structurally equivalent meat-like products. These products are referred to as meat substitutes. Some terminology for meat substitutes includes meat replacers, meat analogues, meat imitations, nonmeat protein alternatives, meatless meats, man-made meats, artificial meats, meat-like meats, mock meats, faux meats, and fake meats. These can be partial or full substitutes for meat, and there is an extensive range of textures. The term “meat analogue” usually refers to products that have a similar look, texture, taste, and color to meat but do not include any meat.
  • 2.2K
  • 30 Sep 2022
Topic Review
Application of Bioactive Compounds in the Food Industry
The fruit production and processing sectors produce tremendous amounts of by-products and waste that cause significant economic losses and an undesirable impact on the environment. The effective utilization of these fruit wastes can help to reduce the carbon footprint and greenhouse gas emissions, thereby achieving sustainable development goals. These by-products contain a variety of bioactive compounds, such as dietary fiber, flavonoids, phenolic compounds, antioxidants, polysaccharides, and several other health-promoting nutrients and phytochemicals. These bioactive compounds can be extracted and used as value-added products in different industrial applications. The bioactive components extracted can be used in developing nutraceutical products, functional foods, or food additives.
  • 2.2K
  • 18 May 2023
Topic Review
Level Mountain
Level Mountain is a large volcanic complex in the Northern Interior of British Columbia, Canada. It is located 50 kilometres (31 miles) north-northwest of Telegraph Creek and 60 kilometres (37 miles) west of Dease Lake on the Nahlin Plateau. With a maximum elevation of 2,164 metres (7,100 feet), it is the second-highest of four large complexes in an extensive north–south trending volcanic region. Much of the mountain is gently-sloping; when measured from its base, Level Mountain is about 1,100 metres (3,600 feet) tall, slightly taller than its neighbour to the northwest, Heart Peaks. The lower, broader half of Level Mountain consists of a shield-like structure while its upper half has a more steep, jagged profile. Its broad summit is dominated by the Level Mountain Range, a small mountain range with prominent peaks cut by deep valleys. These valleys serve as a radial drainage for several small streams that flow from the mountain. Meszah Peak is the only named peak in the Level Mountain Range. The mountain began forming about 15 million years ago, with volcanism having continued up until geologically recent times. There have been four stages of activity throughout the long volcanic history of Level Mountain. The first stage commenced 14.9 million years ago with the eruption of voluminous lava flows; these created a large shield volcano. The second stage began 7.1 million years ago to form a structurally complicated stratovolcano located centrally atop the shield. A series of lava domes was established during the third stage, which began 4.5 million years ago. This was followed by the fourth and final stage with the eruption of lava flows and small volcanic cones in the last 2.5 million years. A wide range of rock types were produced during these stages, namely ankaramites, alkali basalts, trachybasalts, mugearites, hawaiites, phonolites, trachytes and rhyolites. Alkali basalts and ankaramites are the most voluminous and comprise much of Level Mountain. The remaining rock types are less extensive and are largely restricted to the central region of the volcanic complex. Several types of volcanic eruptions produced these rocks. Level Mountain lies in one of many ecoregions encompassing British Columbia. It can be ecologically divided into three sections: lodgepole pine and white spruce forests at its base, bog birch and subalpine fir forests on its flanks, and an alpine climate at its summit. The extent and flatness of the alpine on Level Mountain have produced many Arctic affinities that are particularly noticeable in the local biota. Several animal species thrive in the area of Level Mountain, with caribou being the most abundant. A trading post was established at Level Mountain in the 1890s, followed by geological studies of the mountain from the 1920s onwards. This remote area of Cassiar Land District has a relatively dry environment compared to the Coast Mountains in the west. Due to its remoteness, Level Mountain can only be accessed by air or by trekking great distances on foot. The closest communities are more than 30 kilometres (19 miles) away from the mountain.
  • 2.2K
  • 02 Nov 2022
Topic Review
Epigenetic Mechanisms of Plant Adaptation
Unlike animals, plants are immobile and could not actively escape the effects of aggressive environmental factors, such as pathogenic microorganisms, insect pests, parasitic plants, extreme temperatures, drought, and many others. To counteract these unfavorable encounters, plants have evolved very high phenotypic plasticity. In a rapidly changing environment, adaptive phenotypic changes often occur in time frames that are too short for the natural selection of adaptive mutations. Probably, some kind of epigenetic variability underlines environmental adaptation in these cases. Indeed, isogenic plants often have quite variable phenotypes in different habitats. There are examples of successful “invasions” of relatively small and genetically homogenous plant populations into entirely new habitats. The unique capability of quick environmental adaptation appears to be due to a high tendency to transmit epigenetic changes between plant generations. Multiple studies show that epigenetic memory serves as a mechanism of plant adaptation to a rapidly changing environment and, in particular, to aggressive biotic and abiotic stresses. In wild nature, this mechanism underlies, to a very significant extent, plant capability to live in different habitats and endure drastic environmental changes. In agriculture, a deep understanding of this mechanism could serve to elaborate more effective and safe approaches to plant protection.
  • 2.2K
  • 02 Nov 2020
Topic Review
Ubiquitin-Proteasome System
Kidney transplantation is the preferred treatment for end-stage kidney disease (ESKD). Compared to maintenance dialysis, kidney transplantation results in improved patient survival and quality of life. Kidneys from living donors perform best; however, many patients with ESKD depend on kidneys from deceased donors. After procurement, donor kidneys are placed in a cold-storage solution until a suitable recipient is located. Sadly, prolonged cold storage times are associated with inferior transplant outcomes; therefore, in most situations when considering donor kidneys, long cold-storage times are avoided. The identification of novel mechanisms of cold-storage-related renal damage will lead to the development of new therapeutic strategies for preserving donor kidneys; to date, these mechanisms remain poorly understood. In this review, we discuss the importance of mitochondrial function, protein homeostasis, and renal recovery during stress from cold storage plus transplantation. Additionally, we discuss novel targets for therapeutic intervention.
  • 2.2K
  • 09 Nov 2020
Topic Review
Metal-Assisted Chemical Etching
The metal-assisted chemical etching (MACE) technique is commonly employed for texturing the wafer surfaces when fabricating black silicon (BSi) solar cells and is considered to be a potential technique to improve the efficiency of traditional Si-based solar cells.
  • 2.2K
  • 11 Nov 2021
Topic Review
Carbonation of Concrete
As one of the major causes of concrete deterioration, the carbonation of concrete has been widely investigated over recent decades. In recent years, the effect of mechanical load on carbonation has started to attract more attention. The load-induced variations in crack pattern and pore structure have a significant influence on CO2 transport which determines the carbonation rate. 
  • 2.2K
  • 07 Dec 2021
Topic Review
Sugar Transporters in Plants
Phytohormone transporters, alkaloid transporters, ion and ion chelator transporters, sugar transporters, and amino acid transporters are common active transporters in plants. The examples of phytohormone transporters, alkaloid transporters, and ion and ion chelator transporters include ATP-binding cassette (ABC) transporters and Multidrug And Toxic compound Extrusion (MATE) transporters, while the examples of sugar transporters include MonoSaccharide Transporters (MSTs) and SUcrose Transporters (SUTs). These transporters have been reported to play important roles in various biological processes including cellular detoxification, nutrient transport, and stress adaptation. 
  • 2.2K
  • 17 Mar 2022
Topic Review
Statistical Methods for Food Composition Database Analysis
A food composition database (FCDB) or nutrient database is a compilation of the chemical composition of food and beverage items, obtained from chemical analyses, estimations from published literature, or unpublished laboratory reports. A summary of the statistical methods that have been directly applied to food composition databases and datasets is described here.
  • 2.2K
  • 08 Jun 2022
Topic Review
Nanocatalysts Used in AOPs for Wastewater Treatment
The increase in population demands for industrialization and urbanization which led to the introduction of novel hazardous chemicals in our environment. The most significant parts of these harmful substances found in water bodies remain in the background, causing a health risk to humans and animals. It is critical to remove these toxic chemicals from the wastewater to keep a cleaner and greener environment. Hence, wastewater treatment is a challenging area these days to manage liquid wastes effectively. Therefore, scientists are in search of novel technologies to treat and recycle wastewater, and nanotechnology is one of them, thanks to the potential of nanoparticles to effectively clean wastewater while also being ecologically benign. Advanced oxidation processes (AOPs) have been extensively studied. Advanced oxidation processes can be defined as the processes and technologies which involve the generation of active species such as hydroxyl radicals (•OH) which act as efficient oxidants to decompose pollutants in wastewater treatment. 
  • 2.2K
  • 28 Jul 2022
Topic Review
Produced Water Sustainability in Oil and Gas Sector
Oilfield produced water (PW) is the industry’s principal source of waste byproducts. Oil-producing countries, especially those with limited water resources, face significant difficulty in treating PW for recovery and reuse. Depending on its quality and content, PW can be treated using a variety of technologies. Numerous nations are currently undertaking substantial endeavors to ascertain efficacious and cost-effective treatment methodologies in order to rehabilitate their freshwater supplies. The compositions of pollutants play a major role in the selection of acceptable methods. According to the degree of contamination and the requirement for water quality, several treatment strategies can, therefore, be used. To successfully remove pollutants and/or lessen their detrimental effects on the environment, methods comprising physical, chemical, biological, and membrane treatments have been applied.
  • 2.2K
  • 05 Dec 2023
Topic Review
Moisture Pretreatment for a CEMS
A continuous emission monitoring system (CEMS) is a well-known tool used to analyze the concentrations of air pollutants from stationary sources. In a CEMS, the presence of a high moisture level in a sample causes a loss of analytes due to artifact formation or absorption. This issue brings about a bias in the measurement data. Thus, moisture removal is an important pretreatment step.  
  • 2.2K
  • 25 Jan 2021
Topic Review
Retard Progression of CKD
Chronic kidney disease (CKD), defined as the presence of irreversible structural or functional kidney damages, increases the risk of poor outcomes due to its association with multiple complications, including altered mineral metabolism, anemia, metabolic acidosis, and increased cardiovascular events. The mainstay of treatments for CKD lies in the prevention of the development and progression of CKD as well as its complications.
  • 2.2K
  • 08 Oct 2021
Topic Review
Dynamic Hand Gesture Recognition
  As one of the most important tools of human-computer interaction, dynamic gesture recognition technology has attracted great attention and been applied to various industries. Meanwhile, with the advent of some high-precision deep vision sensors, the reliable data can be achieved for dynamic gesture recognition. Currently, however, the researches of dynamic gesture recognition still has certain limitations and challenges. In order to explore more methods to improve the performance of the dynamic gesture recognition, based on the Leap Motion Controller, a recognition system was proposed to recognize American Sign Language and some daily gestures.
  • 2.2K
  • 30 Oct 2020
Topic Review
The Fungi That Degrade Plastic
Plastic has become established over the world as an essential basic need for our daily life. Plastics have many characteristics such as low production costs, inertness, relatively low weight, and durability. The primary disadvantage of plastics is their extremely slow natural degradation. The latter results in an accumulation of plastic waste in nature. Many fungi can be used to degrade plastics.
  • 2.2K
  • 03 Aug 2022
Topic Review
Business Process Outsourcing
Business process outsourcing (BPO) is a subset of outsourcing that involves the contracting of the operations and responsibilities of a specific business process to a third-party service provider. Originally, this was associated with manufacturing firms, such as Coca-Cola that outsourced large segments of its supply chain. BPO is typically categorized into back office outsourcing, which includes internal business functions such as human resources or finance and accounting, and front office outsourcing, which includes customer-related services such as contact centre services. BPO that is contracted outside a company's country is called offshore outsourcing. BPO that is contracted to a company's neighbouring (or nearby) country is called nearshore outsourcing. Often the business processes are information technology-based, and are referred to as ITES-BPO, where ITES stands for Information Technology Enabled Service. Knowledge process outsourcing (KPO) and legal process outsourcing (LPO) are some of the sub-segments of business process outsourcing industry.
  • 2.2K
  • 18 Oct 2022
Topic Review
Study of Animal Locomotion
The study of animal locomotion is a branch of biology that investigates and quantifies how animals move.
  • 2.2K
  • 24 Oct 2022
Topic Review
Electric Vehicle Charging Connector Standards
For Electric Vehicles (EVs), the electric charge of the battery is the main fuel to drive the car. To refuel the EV, we have to connect the EV to a charging station. For the EV charging pile, there are two options are available: (a) AC charging pile and (b) DC charging pile. The dedicated connector standards are used to connect the EV with AC and/or DC charging stations. The specifications of different connector standards are described in detail with pin configuration and comparative discussion.  
  • 2.2K
  • 01 Nov 2022
Topic Review
Dragonchain
Dragonchain is a hybrid blockchain platform for enterprises and developers. It was originally developed at The Walt Disney Company in Seattle in 2014 and then open-sourced in 2016. Despite extensive speculation, there is no current relationship between Disney and Dragonchain. The open source code is maintained by the Dragonchain Foundation. The commercial blockchain platform is maintained by the commercial entity named The Dragon Company. Dragonchain is a public/private hybrid blockchain platform that allows integration with other blockchain protocols, legacy systems, oracles, and API's. Developers can use existing smart contracts from the library or write their own smart contracts to build (decentralized) blockchain applications in known languages. In 2020, Medek Health launched Covid SafePass with the City of Apopka, using Dragonchain blockchain solutions in line with the FDA guidance on Digital Health Policies and Public Health Solutions for COVID-19.
  • 2.2K
  • 21 Nov 2022
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