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Topic Review
Low-Temperature SCR Catalyst Development
In recent years, low-temperature SCR (Selective Catalytic Reduction) denitrification technology has been popularized in non-power industries and has played an important role in the control of industrial flue gas NOx emissions in China. Currently, the most commonly used catalysts in industry are V2O5-WO3(MoO3)/TiO2, MnO2-based catalysts, CeO2-based catalysts, MnO2-CeO2 catalysts and zeolite SCR catalysts. The flue gas emitted during industrial combustion usually contains SO2, moisture and alkali metals, which can affect the service life of SCR catalysts.
  • 2.4K
  • 31 Mar 2022
Topic Review
Fiber-Reinforced Polymer Composites in the Construction of Bridges
Fiber-reinforced polymer (FRP) composites are two-phase materials consisting of a base material and filler material. Base material is referred as a matrix or a binder material. This is a polymer (plastic), either thermoset or thermoplastic. Polymer matrices are natural or synthetic. The latter kind is petrochemical-based and includes polyester, polypropylene (PP), polyethylene (PE) and epoxy. Due to its specific mechanical properties, a polymer matrix needs to be reinforced by filler material. FRP composites consist of fibers or other reinforcing material, which provide sufficient strength in one or more directions. 
  • 2.4K
  • 05 May 2022
Topic Review
Thousand-Year Rose
The Thousand-year Rose (German: Tausendjähriger Rosenstock, literally: Thousand-year-old Rosebush) is also known as the Rose of Hildesheim. It grows on the apse of the Hildesheim Cathedral, a Catholic cathedral in Hildesheim, Germany, that is dedicated to the Assumption of Mary. The cathedral and the adjacent St. Michael's Church have been on the UNESCO list of World Heritage Sites since 1985. The rose that climbs on the wall of the cathedral's apse is believed to be the oldest living rose in the world. A Rosa canina, commonly known as a wild dog rose, grows against the eastern apse of the cathedral, which is around 21 metres (69 ft) high and 9 metres (30 ft) wide. The rose bush reaches a height of around 10 metres (33 ft) and documentation verifies its age at approximately 700 years. Slight variations arise in the tale of the establishment of the diocese by King Louis the Pious at Hildesheim in 815 but the rose bush is a common theme in all versions. The cathedral was destroyed by Allied bombers in 1945 during the Second World War, but the roots of the rose bush survived and it blossomed again among the ruins. According to legend, while the rose bush flourishes, Hildesheim will prosper. A poem about the rose was published in 1896. In the early twentieth century, after visiting the cathedral and seeing the rose, author Mabel Wagnalls was inspired to write a book, which went on to form the basis of a silent film.
  • 2.4K
  • 08 Nov 2022
Topic Review
Traffic Flow Prediction
The accurate and effective prediction of the traffic flow of vehicles plays a significant role in the construction and planning of signalized road intersections. The application of artificially intelligent predictive models in the prediction of the performance of traffic flow has yielded positive results. However, much uncertainty still exists in the determination of which artificial intelligence methods effectively resolve traffic congestion issues, especially from the perspective of the traffic flow of vehicles at a four-way signalized road intersection.
  • 2.4K
  • 23 Jun 2025
Topic Review
Microbes under Salt-Affected Soils
The salinization of soil is responsible for the reduction in the growth and development of plants. As the global population increases day by day, there is a decrease in the cultivation of farmland due to the salinization of soil, which threatens food security. Salt-affected soils occur all over the world, especially in arid and semi-arid regions. The total area of global salt-affected soil is 1 billion ha, and in India, an area of nearly 6.74 million ha−1 is salt-stressed, out of which 2.95 million ha−1 are saline soil (including coastal) and 3.78 million ha−1 are alkali soil. The rectification and management of salt-stressed soils require specific approaches for sustainable crop production. Remediating salt-affected soil by chemical, physical and biological methods with available resources is recommended for agricultural purposes. Bioremediation is an eco-friendly approach compared to chemical and physical methods. The role of microorganisms has been documented by many workers for the bioremediation of such problematic soils. Halophilic Bacteria, Arbuscular mycorrhizal fungi, Cyanobacteria, plant growth-promoting rhizobacteria and microbial inoculation have been found to be effective for plant growth promotion under salt-stress conditions. The microbial mediated approaches can be adopted for the mitigation of salt-affected soil and help increase crop productivity. A microbial product consisting of beneficial halophiles maintains and enhances the soil health and the yield of the crop in salt-affected soil.
  • 2.4K
  • 12 Aug 2022
Topic Review
Crop Management with the IoT
IoT is becoming a bearing technology for next generation crop management. Cheap networked devices can sense crop fields at a finer grain to give timeliness warnings on the presence of stress conditions and diseases, while on-board devices will monitor field and machine status. Cloud computing allows integrating collected information in a new  generation of FMIS to make decisions and automate field practices by actuators and robot fleets.
  • 2.4K
  • 02 Feb 2021
Topic Review
Oxidative Stress
Oxidative stress (OxS) is considered a major factor in the pathophysiology of inflam-matory chronic liver diseases, including non-alcoholic liver disease (NAFLD). Chronic impairment of lipid metabolism is closely related to alterations of the oxidant/antioxidant balance, which affect metabolism-related organelles, leading to cellular lipotoxicity, lipid peroxidation, chronic endo-plasmic reticulum (ER) stress, and mitochondrial dysfunction. Increased OxS also triggers hepatocytes stress pathways, leading to inflammation and fibrogenesis, contributing to the pro-gression of non-alcoholic steatohepatitis (NASH). The antioxidant response, regulated by the Nrf2/ARE pathway, is a key component in this process and counteracts oxidative stress-induced damage, contributing to the restoration of normal lipid metabolism. 
  • 2.4K
  • 27 Jan 2022
Topic Review
Endometrial Sampling Procedures in Cattle
Endometrial infections are a common cause of reproductive loss in cattle. Accurate diagnosis is important to reduce the economic losses caused by endometritis. A range of sampling procedures have been developed which enable collection of endometrial tissue or luminal cells or uterine fluid. However, as these are all invasive procedures, there is a risk that sampling around the time of breeding may adversely affect subsequent pregnancy rate. 
  • 2.4K
  • 23 Jul 2021
Topic Review
Neurotransmission
Neurotransmission is the process by which a signal is conveyed between neurons via endogenous signaling molecules called neurotransmitters. Neurotransmitters released from the axon terminal of one neuron cross the synaptic cleft and bind to receptors on the dendrites of another neuron, which are then converted into electrical signals. Synapse, the junction between neurons, has a tripartite structure that consists of presynaptic and postsynaptic nerve terminals along with the intimate association of glial cells.
  • 2.4K
  • 26 Jul 2021
Topic Review
Vaccinium uliginosum and Vaccinium myrtillus
Vaccinium uliginosum L. (commonly known as bog bilberry) and Vaccinium myrtillus L. (commonly known as bilberry) are species of the genus Vaccinium (family Ericaceae). The red–purple–blue coloration of blueberries is attributed largely to the anthocyanins found in bilberries. Anthocyanins, known for their potent biological activity as antioxidants, have a significant involvement in the prophylaxis of cancer or other diseases, including those of metabolic origin.
  • 2.4K
  • 06 Dec 2023
Topic Review
Dutch Expedition to Southern Chile (1643)
The following article analyzes how the Dutch expedition to southern Chile during the 17th century (1642–1643) was narrated, in Dutch and in its translations into German, English, and Spanish, considering the interests of empires and the discursive differences that translational variations reveal. This transdisciplinary analysis, combining historiography, translation studies, and historical geography, consists of a critical reading of the original narration and a comparative reading of the aforementioned translations, and within them ethnographic representations made about the Mapuche-Huilliche people and the city of Valdivia and changes introduced by different translations are identified.
  • 2.4K
  • 04 Jan 2024
Topic Review
Media Education
Media Education is an educational discipline focused on critical and conscious engagement with media and their languages. Regarded as complex cultural artifacts, it serves as a preparatory phase aimed at developing interpretative and critical skills regarding the media themselves. The objective is to promote a deep understanding of media as cultural and social phenomena, emphasizing that they are not merely technical tools but carriers of meanings and values that shape perceptions of reality and identity formation. This entry explores the evolution of Media Education, from the 1982 UNESCO Grünwald Declaration to recent international initiatives, highlighting the role of the Media Educator as a facilitator in integrating digital technologies into educational contexts. Key aspects include the rejection of an “apocalyptic” vision of the new media (quoting Umberto Eco), the focus on media as carriers of meaning, and the promotion of critical and creative skills essential for navigating the complexities of contemporary digital culture.
  • 2.4K
  • 21 Jan 2025
Topic Review
Intelligent Buildings in Smart Grids
During the last decade, the smart grid (SG) concept has started to become a reality, mainly thanks to the technical progress achieved in telecommunications, informatics and power electronics, among other domains, leading to an evolution of the traditional electrical grid into an intelligent one. Nowadays, the SG can be seen as a system of smart systems that include cyber and physical parts from different technologies that interact with each other. In this context, intelligent buildings (IBs) constitute a paradigm in which such smart systems are able to guarantee the comfort of residents while ensuring an appropriate tradeoff of energy production and consumption by means of an energy management system (EMS).
  • 2.4K
  • 08 Jun 2021
Topic Review
Interferon Gamma
Interferon gamma (IFN-γ) is a dimerized soluble cytokine that is the only member of the type II class of interferons. The existence of this interferon, which early in its history was known as immune interferon, was described by E. F. Wheelock as a product of human leukocytes stimulated with phytohemagglutinin, and by others as a product of antigen-stimulated lymphocytes. It was also shown to be produced in human lymphocytes. or tuberculin-sensitized mouse peritoneal lymphocytes challenged with Mantoux test (PPD); the resulting supernatants were shown to inhibit growth of vesicular stomatitis virus. Those reports also contained the basic observation underlying the now widely employed IFN-γ release assay used to test for tuberculosis. In humans, the IFN-γ protein is encoded by the IFNG gene.
  • 2.4K
  • 28 Apr 2023
Topic Review
DOF Transcription Factors in Seed
The DOF (DNA BINDING WITH ONE FINGER) family of plant-specific TF (transcription factors) was first identified in maize in 1995. Since then, DOF proteins have been shown to be present in the whole plant kingdom, including the unicellular alga Chlamydomonas reinhardtii. The DOF TF family is characterised by a highly conserved DNA binding domain (DOF domain), consisting of a CX2C-X21-CX2C motif, which is able to form a zinc finger structure. Early in the study of DOF proteins, their relevance for seed biology became clear. Indeed, the PBF (PROLAMIN BINDING FACTOR), one of the first DOF proteins characterised, controls the endosperm-specific expression of the zein genes in maize. Subsequently, several DOF proteins from both monocots and dicots have been shown to be primarily involved in seed development, dormancy and germination, as well as in seedling development and other light-mediated processes. In the last two decades, the molecular network underlying these processes have been outlined, and the main molecular players and their interactions have been identified. In this review, we will focus on the DOF TFs involved in these molecular networks, and on their interaction with other proteins.  
  • 2.4K
  • 28 Oct 2020
Topic Review
Carbon nanotubes (CNTs)
Carbon nanotubes (CNTs) are considered a promising nanomaterial for diverse applications owing to their attractive physicochemical properties such as high surface area, superior mechanical and thermal strength, electrochemical activity, and so on.
  • 2.4K
  • 10 Sep 2020
Topic Review
Intravenous Coenzyme Q10 Administration in Emergency Ischemic Conditions
Coenzyme CoQ10 (CoQ10) is an endogenous lipid-soluble antioxidant that effectively protects lipids, proteins, and DNA from oxidation due to its ability to undergo redox transitions between oxidized and reduced forms. Various oxidative stress-associated infectious and somatic diseases have been observed to disrupt the balance of CoQ10 concentration in tissues. As a high molecular weight polar lipophilic compound, CoQ10 exhibits very limited oral bioavailability, which restrains its therapeutic potential. Nevertheless, numerous studies have confirmed the clinical efficacy of CoQ10 therapy through oral administration of high doses over extended time periods. Experimental studies have demonstrated that in emergency situations, intravenous administration of both oxidized and reduced-form CoQ10 leads to a rapid increase in its concentration in organ tissues, offering protection for organ tissues in ischemic conditions. This suggests that the cardio- and neuroprotective efficacy of intravenously administered CoQ10 forms could present new opportunities in treating acute ischemic conditions. 
  • 2.4K
  • 25 Mar 2024
Topic Review Peer Reviewed
Generative AI and Large Language Models in Industry 5.0: Shaping Smarter Sustainable Cities
This review paper examines how Generative AI (GAI) and Large Language Models (LLMs) can transform smart cities in the Industry 5.0 era. Through selected case studies and portions of the literature, we analyze these technologies’ impact on industrial processes and urban management. The paper targets GAI as an enabler for industrial optimization and predictive maintenance, underlining how domain experts can work with LLMs to improve municipal services and citizen communication, while addressing the practical and ethical challenges in deploying these technologies. We also highlight promising trends, as reflected in real-world case studies ranging from factories to city-wide test-beds and identify pitfalls to avoid. Widespread adoption of GAI still faces challenges that include infrastructure and lack of specialized knowledge as a limitation of proper implementation. While LLMs enable new services for citizens in smart cities, they also expose certain privacy issues, which we aim to investigate in this study. Finally, as a way forward, the paper suggests future research directions covering new ethical AI frameworks and long-term studies on societal impacts. Our paper is a starting point for industrial pioneers and urban developers to navigate the complexity of GAI and LLM integration, balancing the demands of technological innovation on one hand and ethical responsibility on the other.
  • 2.4K
  • 06 Mar 2025
Topic Review
Chromosomal instability in Fanconi anemia
Fanconi anemia (FA), a chromosomal instability syndrome, is caused by inherited pathogenic variants in any of 22 FANC genes, which cooperate in the FA/BRCA pathway. This pathway regulates the repair of DNA interstrand crosslinks (ICLs) through homologous recombination. In FA proper repair of ICLs is impaired and accumulation of toxic DNA double strand breaks occurs. To repair this type of DNA damage, FA cells activate alternative error-prone DNA repair pathways, which may lead to the formation of gross structural chromosome aberrations of which radial figures are the hallmark of FA, and their segregation during cell division are the origin of subsequent aberrations such as translocations, dicentrics and acentric fragments. The deficiency in DNA repair has pleiotropic consequences in the phenotype of patients with FA, including developmental alterations, bone marrow failure and an extreme risk to develop cancer.
  • 2.4K
  • 15 Jan 2021
Topic Review
Gestational Diabetes Mellitus (GDM)
Gestational Diabetes Mellitus (GDM) is a transient condition characterized by carbohydrate intolerance, hyperglycemia, peripheral insulin resistance, insufficient insulin secretion or activity, endothelial dysfunction, and low-grade inflammation during pregnancy, frequently with the first onset between 24 and 28 weeks of gestation.
  • 2.4K
  • 28 Sep 2021
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