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Topic Review
Road Infrastructure Maintenance Management
Management of nonurban road network maintenance is a complex management process that requires the inclusion of many technical, economic, and other characteristics of the problem, as well as the continuous application of new knowledge and approaches, to maintenance management. To effectively manage the maintenance of the road network in conditions of limited financial resources, maintenance is examined through three interrelated management functions of planning: implementation, monitoring, and maintenance control. 
  • 2.4K
  • 20 Jun 2022
Topic Review
Neurotransmission
Neurotransmission is the process by which a signal is conveyed between neurons via endogenous signaling molecules called neurotransmitters. Neurotransmitters released from the axon terminal of one neuron cross the synaptic cleft and bind to receptors on the dendrites of another neuron, which are then converted into electrical signals. Synapse, the junction between neurons, has a tripartite structure that consists of presynaptic and postsynaptic nerve terminals along with the intimate association of glial cells.
  • 2.4K
  • 26 Jul 2021
Topic Review
The Influence of CSR and Ethics on Brand
Business ethics and corporate social responsibility (CSR) exert an indirect positive effect on brand fidelity, with relationships mediated by brand love. In turn, brand attitude exerts an indirect effect on brand fidelity, through the mediation of brand love. 
  • 2.4K
  • 28 Mar 2022
Topic Review
Waste Electrical and Electronic Equipment
Waste electrical and electronic equipment (WEEE), or e-waste, faces significant sustainability challenges. Characterised by high economic elasticity, i.e. a close correlation between WEEE generation and Gross Domestic Product (GDP), WEEE is one of the fastest growing waste streams worldwide. Hazardous components require attention, while at the same time the potential to implement circular economy schemes with recuperation of valuable components is particularly high for e-waste. An overview on key aspects related to sound management of e-waste is provided in the following.
  • 2.4K
  • 05 Nov 2020
Topic Review
DOF Transcription Factors in Seed
The DOF (DNA BINDING WITH ONE FINGER) family of plant-specific TF (transcription factors) was first identified in maize in 1995. Since then, DOF proteins have been shown to be present in the whole plant kingdom, including the unicellular alga Chlamydomonas reinhardtii. The DOF TF family is characterised by a highly conserved DNA binding domain (DOF domain), consisting of a CX2C-X21-CX2C motif, which is able to form a zinc finger structure. Early in the study of DOF proteins, their relevance for seed biology became clear. Indeed, the PBF (PROLAMIN BINDING FACTOR), one of the first DOF proteins characterised, controls the endosperm-specific expression of the zein genes in maize. Subsequently, several DOF proteins from both monocots and dicots have been shown to be primarily involved in seed development, dormancy and germination, as well as in seedling development and other light-mediated processes. In the last two decades, the molecular network underlying these processes have been outlined, and the main molecular players and their interactions have been identified. In this review, we will focus on the DOF TFs involved in these molecular networks, and on their interaction with other proteins.  
  • 2.4K
  • 28 Oct 2020
Topic Review
Advanced Glycation End Products (AGEs)
The Maillard reaction is a simple but ubiquitous reaction that occurs both in vivo and ex vivo during the cooking or processing of foods under high-temperature conditions, such as baking, frying, or grilling. Glycation of proteins is a post-translational modification that forms temporary adducts, which, on further crosslinking and rearrangement, form permanent residues known as advanced glycation end products (AGEs). Cooking at high temperature results in various food products having high levels of AGEs. This review underlines the basis of AGE formation and their corresponding deleterious effects on the body. Glycated Maillard products have a direct association with the pathophysiology of some metabolic diseases, such as diabetes mellitus type 2 (DM2), acute renal failure (ARF), Alzheimer’s disease, dental health, allergies, and polycystic ovary syndrome (PCOS). The most glycated and structurally abundant protein is collagen, which acts as a marker for diabetes and aging, where decreased levels indicate reduced skin elasticity. In diabetes, high levels of AGEs are associated with carotid thickening, ischemic heart disease, uremic cardiomyopathy, and kidney failure. AGEs also mimic hormones or regulate/modify their receptor mechanisms at the DNA level. In women, a high AGE diet directly correlates with high levels of androgens, anti-Müllerian hormone, insulin, and androstenedione, promoting ovarian dysfunction and/or infertility. Vitamin D3 is well-associated with the pathogenesis of PCOS and modulates steroidogenesis. It also exhibits a protective mechanism against the harmful effects of AGEs.
  • 2.4K
  • 28 Jul 2021
Topic Review
Traffic Flow Prediction
The accurate and effective prediction of the traffic flow of vehicles plays a significant role in the construction and planning of signalized road intersections. The application of artificially intelligent predictive models in the prediction of the performance of traffic flow has yielded positive results. However, much uncertainty still exists in the determination of which artificial intelligence methods effectively resolve traffic congestion issues, especially from the perspective of the traffic flow of vehicles at a four-way signalized road intersection.
  • 2.4K
  • 23 Jun 2025
Topic Review Peer Reviewed
Generative AI and Large Language Models in Industry 5.0: Shaping Smarter Sustainable Cities
This review paper examines how Generative AI (GAI) and Large Language Models (LLMs) can transform smart cities in the Industry 5.0 era. Through selected case studies and portions of the literature, we analyze these technologies’ impact on industrial processes and urban management. The paper targets GAI as an enabler for industrial optimization and predictive maintenance, underlining how domain experts can work with LLMs to improve municipal services and citizen communication, while addressing the practical and ethical challenges in deploying these technologies. We also highlight promising trends, as reflected in real-world case studies ranging from factories to city-wide test-beds and identify pitfalls to avoid. Widespread adoption of GAI still faces challenges that include infrastructure and lack of specialized knowledge as a limitation of proper implementation. While LLMs enable new services for citizens in smart cities, they also expose certain privacy issues, which we aim to investigate in this study. Finally, as a way forward, the paper suggests future research directions covering new ethical AI frameworks and long-term studies on societal impacts. Our paper is a starting point for industrial pioneers and urban developers to navigate the complexity of GAI and LLM integration, balancing the demands of technological innovation on one hand and ethical responsibility on the other.
  • 2.4K
  • 06 Mar 2025
Topic Review
Journal JRFM
Journal of Risk and Financial Management (ISSN 1911-8074; ISSN 1911-8066 for printed edition) is an international, peer-reviewed, open access journal on risk and financial management. JRFM was formerly edited by Prof. Dr. Raymond A.K. Cox and published by Prof. Dr. Alan Wong online in one yearly volume from 2008 until end 2012. Since October 2013, it is published monthly and online by MDPI. International Engineering and Technology Institute (IETI), Institute of Data Science and Artificial Intelligence (IDSAI), International Research Institute for Economics and Management (IRIEM) are affiliated to Journal of Risk and Financial Management (JRFM) and their members receive a discount on the article processing charges. Manuscripts are peer-reviewed and a first decision provided to authors approximately 13.9 days after submission; acceptance to publication is undertaken in 2.9 days (median values for papers published in this journal in the second half of 2020).
  • 2.4K
  • 26 Sep 2021
Topic Review
Eton College Controversies
There have been many controversies concerning Eton College, including those listed below. Eton College is a well-known independent boarding school for boys in Berkshire, England, United Kingdom, sometimes called the most famous school in the world. The Guardian claimed that 'Eton is no stranger to scandalous allegations, nor to claims that it tries to prevent them leaking out.'
  • 2.4K
  • 17 Oct 2022
Topic Review
Asteraceae
Recent studies show that searching for new possibilities of phytotherapy using compounds isolated from Centaureinae plants is worth the effort. Treatment based on active substances from plants of the Centaureinae subtribe is often effective and does not cause side effects, as was demonstrated on an example of antifungal infections and SD and melasma and lentigo solaris treatment.
  • 2.4K
  • 09 Dec 2020
Topic Review
Biocomposites
Biocomposites are an emerging material class with the potential to reduce a product’s through-life environmental impact relative to wholly synthetic composites. As with most materials, there are challenges and opportunities with the adoption of biocomposites at the each stage of the life cycle.
  • 2.4K
  • 15 Apr 2021
Topic Review
Endometrial Sampling Procedures in Cattle
Endometrial infections are a common cause of reproductive loss in cattle. Accurate diagnosis is important to reduce the economic losses caused by endometritis. A range of sampling procedures have been developed which enable collection of endometrial tissue or luminal cells or uterine fluid. However, as these are all invasive procedures, there is a risk that sampling around the time of breeding may adversely affect subsequent pregnancy rate. 
  • 2.4K
  • 23 Jul 2021
Topic Review
Welding between Batteries and Busbars for Electric Vehicles
Electric vehicle battery systems are made up of a variety of different materials, each battery system contains hundreds of batteries. There are many parts that need to be connected in the battery system, and welding is often the most effective and reliable connection method. Laser welding has the advantages of non-contact, high energy density, accurate heat input control, and easy automation, which is considered to be the ideal choice for electric vehicle battery manufacturing. In all the production processes of power battery packs, there is a key process, that is, the welding of a single lithium battery and the connector. This is the key to the quality of series and parallel lithium-ion battery cells, that is, the welding of the battery pole and the busbars. The quality of the welding here will directly affect the reliability of the quality of the lithium-ion battery pack used as a power source for electric vehicles.
  • 2.4K
  • 14 Aug 2023
Topic Review
Microbes under Salt-Affected Soils
The salinization of soil is responsible for the reduction in the growth and development of plants. As the global population increases day by day, there is a decrease in the cultivation of farmland due to the salinization of soil, which threatens food security. Salt-affected soils occur all over the world, especially in arid and semi-arid regions. The total area of global salt-affected soil is 1 billion ha, and in India, an area of nearly 6.74 million ha−1 is salt-stressed, out of which 2.95 million ha−1 are saline soil (including coastal) and 3.78 million ha−1 are alkali soil. The rectification and management of salt-stressed soils require specific approaches for sustainable crop production. Remediating salt-affected soil by chemical, physical and biological methods with available resources is recommended for agricultural purposes. Bioremediation is an eco-friendly approach compared to chemical and physical methods. The role of microorganisms has been documented by many workers for the bioremediation of such problematic soils. Halophilic Bacteria, Arbuscular mycorrhizal fungi, Cyanobacteria, plant growth-promoting rhizobacteria and microbial inoculation have been found to be effective for plant growth promotion under salt-stress conditions. The microbial mediated approaches can be adopted for the mitigation of salt-affected soil and help increase crop productivity. A microbial product consisting of beneficial halophiles maintains and enhances the soil health and the yield of the crop in salt-affected soil.
  • 2.4K
  • 12 Aug 2022
Topic Review
ROS-Responsive Cell Harvesting Methods
Cell sheet engineering has evolved rapidly over the last few years and as a new approach for cell-based therapy. Cell sheet harvest technology is important for producing viable, transplantable cell sheets and applying them to tissue engineering. To date, various approaches have been reported for harvesting cell sheets by inducing property changes of the culture surface such as wettability, pH, electricity, and magnetism. This section provides a comprehensive introduction to reactive oxygen species (ROS) and the progress of new strategies for applying ROS in cell sheet detachment.
  • 2.4K
  • 13 Oct 2021
Topic Review
Reconfigurable Vectorial Thrusters
The reconfigurable vectorial thruster (RVT) is a propulsion element that changes not only the intensity of the thrust vector but also its direction. This vector reorientation by a servomotor, for example, is usually faster than the intensity change. Thus, the possibility of fast vehicle reconfiguration allows the optimized choice of the reconfigured propulsion architecture according to different tasks, minimizing the trajectory tracking error and energy consumption. Moreover, the use of RVTs can significantly reduce the total number of needed thrusters in a vehicle.
  • 2.4K
  • 19 Mar 2021
Topic Review
Pleiotropic Effects of Aldosterone in Diabetic Kidney Disease
Diabetic kidney disease (DKD) represents a major public health issue, currently posing an important burden on healthcare systems. Renin–angiotensin system (RAS) blockers are considered the cornerstone of treatment of albuminuric DKD. Aldosterone is a steroid hormone that is produced by the adrenal cortex and acts, together with other members of the steroid hormone family (cortisol and corticosterone), as a ligand of MRs. 
  • 2.4K
  • 05 May 2022
Topic Review
Vidya
Vidya (Sanskrit: विद्या, IAST: vidyā) figures prominently in all texts pertaining to Indian philosophy – meaning science, learning, knowledge, and scholarship. Most importantly, it refers to valid knowledge, which cannot be contradicted, and true knowledge, which is the intuitively-gained knowledge of the self. Vidya is not mere intellectual knowledge, for the Vedas demand understanding.
  • 2.4K
  • 15 Nov 2022
Topic Review
1,3,4-Oxadiazole
Compounds containing 1,3,4-oxadiazole ring in their structure are characterised by multidirectional biological activity.
  • 2.4K
  • 13 Sep 2021
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