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Topic Review
Beneficial effects of Glycine in the Organism
Glycine is an amino acid that our bodies can produce naturally, so we don't necessarily need to get it from our diet. Nevertheless, it plays a vital role in various functions throughout our entire body. Glycine interacts with specific receptors and transporters found in many different types of cells, which allows it to have important effects on our health. One of the most fascinating things about glycine is its potential to reduce inflammation in our body. Researchers have conducted many studies focusing on this aspect. Glycine has been shown to decrease pro-inflammatory molecules called cytokines, which are responsible for promoting inflammation. Additionally, it can lower the levels of free fatty acids, which are sometimes linked to inflammation in certain situations. Moreover, glycine seems to positively influence how our body responds to insulin, which is crucial for maintaining stable blood sugar levels. It also appears to bring about other beneficial changes in our body, although scientists are still investigating the specific details of these effects. Glycine is a remarkable amino acid that offers many health benefits, especially in terms of reducing inflammation and possibly enhancing how our bodies respond to insulin. It's fascinating because it is present throughout our entire body, and we can obtain it through our diet or nutraceuticals, affecting our health in various ways. Scientists continue to study glycine to unlock its full potential and better understand its role in supporting our well-being.
  • 2.7K
  • 26 Jul 2023
Topic Review
Geopolymer Materials
The advancement of eco-friendly technology in the construction sector has been improving rapidly. As a result, multiple building materials were developed, enhanced, and proposed as replacements for some traditional materials. One notable example presents geopolymer as a substitute for ordinary Portland concrete (OPC). The manufacturing process of (OPC) generates CO2 emissions and a high energy demand, both of which contribute to ozone depletion and global warming. The implementation of geopolymer concrete (GPC) technology in the construction sector provides a path to more sustainable growth and a cleaner environment. This is due to geopolymer concrete’s ability to reduce environmental pollutants and reduce the construction industry’s carbon footprint. This is achieved through its unique composition, which typically involves industrial byproducts like fly ash or slag. These materials, rich in silicon and aluminum, react with alkaline solutions to form a binding gel, bypassing the need for the high-energy clinker production required in OPC. The use of such byproducts not only reduces CO2 emissions but also contributes to waste minimization. Additionally, geopolymer offers extra advantages compared to OPC, including improved mechanical strength, enhanced durability, and good stability in acidic and alkaline settings. Such properties make GPC particularly suitable for a range of construction environments, from industrial applications to infrastructure projects exposed to harsh conditions. 
  • 2.7K
  • 15 Dec 2023
Topic Review
IBM Basic Assembly Language and Successors
Basic Assembly Language (BAL) is the commonly used term for a low-level programming language used on IBM System/360 and successor mainframes. Originally "Basic Assembly Language" applied only to an extremely restricted dialect designed to run under control of IBM Basic Programming Support (BPS/360) on systems with only 8 KB of main memory, and only a card reader, a card punch, and a printer for input/output — thus the word "Basic". However, the full name and the initialism "BAL" almost immediately attached themselves in popular use to all assembly-language dialects on the System/360 and its descendants. BAL for BPS/360 was introduced with the System/360 in 1964. Assemblers on other System/360 operating systems through System/370, System/390, and System z, as well as the UNIVAC Series 90 mainframes made by Sperry Corporation, and the BS2000 Mainframes currently made by Fujitsu, inherited and extended its syntax. The latest derived language is known as the IBM High-Level Assembler (HLASM). Programmers utilizing this family of assemblers also refer to them as ALC, (for Assembly Language Coding), or simply "assembler". BAL is also the mnemonic of the "Branch And Link" instruction.
  • 2.7K
  • 19 Oct 2022
Topic Review
3D City Models
3D city models are digital models of urban areas that represent terrain surfaces, sites, buildings, vegetation, infrastructure and landscape elements in three-dimensional scale as well as related objects (e.g., city furniture) belonging to urban areas. Their components are described and represented by corresponding two-dimensional and three-dimensional spatial data and geo-referenced data. 3D city models support presentation, exploration, analysis, and management tasks in a large number of different application domains. In particular, 3D city models allow "for visually integrating heterogeneous geoinformation within a single framework and, therefore, create and manage complex urban information spaces."
  • 2.7K
  • 04 Nov 2022
Topic Review Peer Reviewed
Analyzing Cultural Routes and Their Role in Advancing Cultural Heritage Management within Tourism: A Systematic Review with a Focus on the Integration of Digital Technologies
This review constitutes a comprehensive systematic review analyzing cultural routes, with a particular focus on the concept of the cultural route as a tourist–cultural product. Within this framework, the paper offers an overview of contemporary technological challenges, concerns, and limitations. It thoroughly explores cutting-edge technologies pertaining to the promotion of cultural heritage, both in general and in the specific context of realizing the concept of the cultural route, a tourist–cultural service enriched by the utilization of new media. Additionally, it extensively references the latest techniques and models for enhancing the user experience of digital cultural tourism products. Moreover, the paper showcases existing digital platforms and tools that encapsulate and emphasize the notion of cultural tourism. It assesses the respective methodologies, technologies, and techniques employed in each case, accompanied by illustrative instances of their applications. Finally, an empirical evaluation was conducted focusing on user needs and expectations during a cultural route.
  • 2.7K
  • 29 Dec 2023
Topic Review
Value
In social sciences, value refers to a deeply held belief or principle that guides individuals' attitudes, behaviors, and decision-making processes. Values are subjective and culturally influenced, reflecting what individuals consider important, desirable, or morally significant in their lives and interactions with others. They serve as guiding principles that shape social norms, institutions, and collective identities within society.
  • 2.7K
  • 02 Feb 2024
Topic Review
A Low-Cost, Flexible Pressure Capacitor Sensor using Polyurethane for Wireless Vehicle Detection
Detection of vehicles on the road can contribute to the establishment of an intelligent transportation management system to allow smooth transportation and the reduction of road accidents. Thus far, an efficient and low-cost polymer flexible pressure sensor for vehicle detection is lacking. This paper presents a flexible sensor for vehicle sensing and demonstrates a wireless system for monitoring vehicles on the road. A vehicle sensor is fabricated by sandwiching a polyurethane material between Aluminum top/bottom electrodes. The sensing mechanism is based on changes in capacitance due to variation in the distance between the two electrodes at an applied external pressure. A clear response against a pressure load of 0.65 Mpa is observed, which is the same pressure as that of the car tire area in contact with the road. Significantly, the sensor is easy to embed on the road line due to its mechanical flexibility and large size. A field test is carried out by embedding the sensor on the road and crossing the sensor with a car. Moreover, the signal displayed on the tablet indicates that the sensing system can be used for wireless detection of the axle, speed, or weight of the vehicle on the road. The findings suggest that the flexible pressure sensor is a promising tool for use as a low-cost vehicle detector in future intelligent transportation management.
  • 2.7K
  • 28 Oct 2020
Topic Review
IgG antibodies
IgG antibodies include two functional portions: the F(ab′)2 fragment, which is responsible for antigen recognition, and the crystallizable fragment (Fc), which is important for activation of the immune response by interacting with Fcγ receptors on B-cells and other innate immune cells. The Fc fragment also plays an important role in the activation of complement and in the clearance of microorganisms.
  • 2.7K
  • 01 Nov 2020
Topic Review
Pyrimidine Biosynthetic Enzyme CAD
CAD (Carbamoyl-phosphate synthetase 2, Aspartate transcarbamoylase, and Dihydroorotase) is a multifunctional protein that participates in the initial three speed-limiting steps of pyrimidine nucleotide synthesis. Over the past two decades, extensive investigations have been conducted to unmask CAD as a central player for the synthesis of nucleic acids, active intermediates, and cell membranes. Meanwhile, the important role of CAD in various physiopathological processes has also been emphasized.
  • 2.7K
  • 27 Oct 2021
Topic Review
E-Cadherin Signaling
E-cadherin, the major epithelial cadherin, is located in regions of cell–cell contact known as adherens junctions. E-cadherin contributes to the maintenance of the epithelial integrity through homophylic interaction; the cytoplasmic tail of E-cadherin directly binds catenins, forming a dynamic complex that regulates several intracellular signal transduction pathways, including epithelial-to-mesenchymal transition (EMT).
  • 2.7K
  • 21 Apr 2022
Topic Review
Methods for Crowd Counting
The crowd counting task has become a pillar for crowd control as it provides information concerning the number of people in a scene. It is helpful in many scenarios such as video surveillance, public safety, and future event planning. To solve such tasks, researchers have proposed different solutions. In the beginning, researchers went with more traditional solutions, then the focus is on deep learning methods and, more specifically, on Convolutional Neural Networks (CNNs), because of their efficiency. 
  • 2.7K
  • 21 Jul 2022
Topic Review
List of Physicians
This is a list of famous physicians in history.
  • 2.7K
  • 14 Nov 2022
Topic Review
Minimum Energy Performance Standards in Colombia
The minimum energy performance standards (MEPS) has become a mandatory government document to evaluate the energy efficiency of different equipment and thus limit the minimum energy consumption in domestic, commercial, and industrial applications, guaranteeing end users are able to select more efficient equipment. In order to be compared with the Colombian panorama at the market, technical and political levels, some reference countries and their energy policies were consulted. This allows the establishment of common aspects and differences related to the determination of energy consumption, adjusted volume, and formalization of efficiency ranges, and in the specific case of domestic refrigeration in Colombia.
  • 2.7K
  • 10 Feb 2023
Topic Review
PD-1/PD-L1 antibody plus Anti-VEGF Inhibitors
A successful phase III trial for the combination of atezolizumab and bevacizumab (the IMbrave150 trial) in advanced hepatocellular carcinoma has recently been reported to show better survival benefit over sorafenib, standard of care for more than 12 years. This is a practice changing results and scientific rationale of this combination, PD-1/PD-L1 antibody plus anti-VEGF inhibitors is very important.
  • 2.7K
  • 18 Dec 2020
Topic Review
Rotational Piezoelectric Energy Harvesting
Rotational Piezoelectric Energy Harvesting (RPZTEH) is widely used due to mechanical rotational input power availability in industrial and natural environments. This paper reviews the recent studies and research in RPZTEH based on its excitation elements and design and their influence on performance. It presents different groups for comparison according to their mechanical inputs and applications, such as fluid (air or water) movement, human motion, rotational vehicle tires, and other rotational operational principal including gears. The work emphasises the discussion of different types of excitations elements, such as mass weight, magnetic force, gravity force, centrifugal force, gears teeth, and impact force, to show their effect on enhancing output power. It revealed that a small compact design with the use of magnetic, gravity, and centrifugal forces as excitation elements and a fixed piezoelectric to avoid a slip ring had a good influence on output power optimisation. One of the interesting designs that future works should focus on is using gear for frequency up-conversion to enhance output power density and keep the design simple and compact.
  • 2.7K
  • 12 Aug 2021
Topic Review
Synthesis of 2,5-Furandicarboxylic Acid
The most versatile furanic building block for chemical and polymer applications is 2,5-furandicarboxylic acid. However, the classical 2,5-furandicarboxylic acid production methodology has been found to have significant drawbacks that hinder industrial-scale production.  The following content highlights new alternative methods to synthesize 2,5-furandicarboxylic acid that are both more advantageous and attractive than conventional oxidation of 5-hydroxymethylfurfural.
  • 2.7K
  • 19 Jul 2022
Topic Review
Caracal
The caracal (Caracal caracal) /ˈkærəkæl/ is a medium-sized wild cat native to Africa, the Middle East, Central Asia, and arid areas of Pakistan and northwestern India . It is characterised by a robust build, long legs, a short face, long tufted ears, and long canine teeth. Its coat is uniformly reddish tan or sandy, while the ventral parts are lighter with small reddish markings. It reaches 40–50 cm (16–20 in) at the shoulder and weighs 8–19 kg (18–42 lb). It was first scientifically described by German naturalist Johann Christian Daniel von Schreber in 1776. Three subspecies are recognised. Typically nocturnal, the caracal is highly secretive and difficult to observe. It is territorial, and lives mainly alone or in pairs. The caracal is a carnivore that typically preys upon small mammals, birds, and rodents. It can leap higher than 4 metres (12 ft) and catch birds in midair. It stalks its prey until it is within 5 m (16 ft) of it, after which it runs it down and kills its prey with a bite to the throat or to the back of the neck. Both sexes become sexually mature by the time they are one year old and breed throughout the year. Gestation lasts between two and three months, resulting in a litter of one to six kittens. Juveniles leave their mothers at the age of nine to ten months, though a few females stay back with their mothers. The average lifespan of captive caracals is nearly 16 years. Caracals were tamed and used for coursing in India, Persia and Egypt.
  • 2.7K
  • 24 Oct 2022
Topic Review
Intercession of the Theotokos
The Intercession of the Theotokos, or the Protection of Our Most Holy Lady Theotokos and Ever-Virgin Mary, is a feast of the Mother of God celebrated in the Eastern Orthodox and Byzantine Catholic Churches. The feast celebrates the protection afforded the faithful through the intercessions of the Theotokos (lit. Mother of God, the Eastern title of the Virgin Mary). In the Slavic Orthodox Churches it is celebrated as the most important solemnity besides the Twelve Great Feasts and Pascha. The feast is commemorated in Eastern Orthodoxy as a whole, but by no means as fervently as it is in Russia , Belarus and Ukraine . It is not a part of the ritual traditions of, and therefore is not celebrated by, the Oriental Orthodox Churches or some jurisdictions that allow Western Rite Orthodoxy. Yet the feast is perfectly consistent with the theology of these sister churches. It is celebrated on October 14 (OS October 1). The Western Rite Communities of the Russian Orthodox Church Outside of Russia (ROCOR) do celebrate this feast on their calendar.
  • 2.7K
  • 24 Nov 2022
Topic Review
Sustainable food consumption in marketing
Lizbeth Salgado-Beltrán & Luis Felipe Beltrán-Morales The objetive is to define the Sustainable food consumption in marketing 
  • 2.7K
  • 30 Oct 2020
Topic Review
Punica Granatum Vrs COVID-19
Punica granatum is historically known worldwide as a versatile medicinal fruit. 2 major varieties are presented (i) indo Ayurvedic type (Punica Ayurvedica ? ) that is small, harsh and yields no juice and (ii) the juice variety which is commercialised. Indo-Iranian joint effort presents a tome of textual data pertaining to the medicinal aspects of Punica. Ayurvedic texts and Occidental research modelled papers in tabulated form chronologically succinctly bringing out the evidence based historiography & medico-cultural heritage. On such platform a range of formulations; fruit-to-finished product are presented for the 1st time machine makeable and very specifically also by hand, at home. Poly pathology spectrum; versatile therapeutic range; medico-legal; lyophilisation; sterilisation; etc. aspects are also indicated. Includes Tablets; Suspensions for General to Geriatric case types. Ground breaking. Frank.
  • 2.7K
  • 27 Oct 2020
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