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Topic Review
Keshi (Demon)
In Hindu mythology, Keshi (Sanskrit: केशी; Keśi, nominative singular masculine from the root Keśin, literally "long haired") is the horse-demon, killed by Krishna, an avatar of the god Vishnu. The demon was dispatched by Krishna's evil uncle Kamsa, who was destined to die at Krishna's hands. The tale of the slaying of Keshi is told in the Hindu scriptures of Bhagavata Purana, Vishnu Purana and Harivamsa. Krishna is often praised as Keshava - the slayer of Keshi - in scriptures. Theories suggested about Keshi's origins range from his being a demon of childhood diseases to the story's being inspired by the Greek Herculean labour of slaying the horses of Diomedes.
  • 2.8K
  • 09 Nov 2022
Topic Review
Pseudoplatystoma Catfishes in the Neotropics
Species of the genus Pseudoplatystoma, the long-whiskered catfishes, are important in commercial and recreational fisheries in South America, and some species have become key to regional aquaculture. Some species of the genus are under pressure due to overfishing and the negative impacts of dams. 
  • 2.8K
  • 14 Jun 2023
Topic Review Peer Reviewed
Healthy Aging in Place with the Aid of Smart Technologies: A Systematic Review
This study evaluates the current scope of smart technology applications that support aging in place and identifies potential avenues for future research. The global demographic shift towards an aging population has intensified interest in technologies that enable older adults to maintain independence and quality of life within their homes. We conducted a systematic review of the scientific literature from Web of Science, PubMed, and ProQuest, identifying 44 smart technologies across 32 publications. These technologies were classified into three categories: nonmobile technologies for individual monitoring, nonmobile technologies for home environment monitoring, and wearable technologies for health and activity tracking. Notably, the research in this area has grown significantly since 2018; yet, notable gaps persist, particularly within the traditional disciplines related to aging and in the use of quantitative methodologies. This emerging field presents substantial opportunities for interdisciplinary research and methodological advancement, highlighting the need for well-developed research strategies to support the effective integration of smart technology in aging in place.
  • 2.8K
  • 20 Dec 2024
Topic Review
Whey Proteins
Whey proteins have implications in different fields related to human life quality. The aim of this overview was to present the basic chemistry of β-lactoglobulin, α-lactalbumin, and lactotransferrin - main proteins of bovine whey. 
  • 2.8K
  • 27 Oct 2020
Topic Review
Atomic Layer Deposition on 2D Materials
Atomic layer deposition (ALD) of high-κ dielectrics on two-dimensional (2D) materials (including graphene and transition metal dichalcogenides) still represents a challenge due to the lack of out-of-plane bonds on the pristine surfaces of 2D materials, thus making the nucleation process highly disadvantaged. The typical methods to promote the nucleation (i.e., the predeposition of seed layers or the surface activation via chemical treatments) certainly improve the ALD growth but can affect, to some extent, the electronic properties of 2D materials and the interface with high-κ dielectrics. Hence, direct ALD on 2D materials without seed and functionalization layers remains highly desirable. In this context, a crucial role can be played by the interaction with the substrate supporting the 2D membrane. In particular, metallic substrates such as copper or gold have been found to enhance the ALD nucleation of Al2O3 and HfO2 both on monolayer (1 L) graphene and MoS2. Similarly, uniform ALD growth of Al2O3 on the surface of 1 L epitaxial graphene (EG) on SiC (0001) has been ascribed to the peculiar EG/SiC interface properties.
  • 2.8K
  • 15 Dec 2021
Topic Review
Deep Learning Algorithms and Their Applications
Deep learning is a type of machine learning that uses artificial neural networks to mimic the human brain. It uses machine learning methods such as supervised, semi-supervised, or unsupervised learning strategies to learn automatically in deep architectures and has gained much popularity due to its superior ability to learn from huge amounts of data.
  • 2.8K
  • 17 Mar 2022
Topic Review
Barriers of Small-Scale Biogas Plants in Indonesia
By 2025, biogas is estimated to become a larger part of Indonesia’s energy mix. Biogas is a renewable energy source that also has economic and environmental advantages. Domestic biogas generation has been embraced in Indonesia as a response to the country’s energy security concerns in rural areas. Since the 1970s, 48,038 biogas plants have been built in the region. To fully develop this technology, Indonesia must discontinue relying on fossil fuels and substitute current fossil-fuel-based energy.
  • 2.8K
  • 25 Jul 2022
Topic Review
Natural Deep Eutectic Solvents for Sustainable Extraction Techniques
The analysis of foods is a comprehensive process of extraction, identification, and quantification of several classes of compounds from natural matrices. The detection and quantification of primary metabolites (sugars, amino acids, vitamins, and lipids), contaminants (toxins, heavy metals, and allergens), and secondary metabolites (polyphenolics, flavonoids, terpenes, and alkaloids) is a crucial practice for ensuring the safety and quality of foods and related functional products. Due to the variable structure of food analytes, a gap in a universal method suitable for the extraction and analysis of all compounds is lacking. Moreover, conventional extractants are usually made of organic solvents and common extraction techniques usually require a long extraction time to exhaust the matrix. The actual discussions about climatic changes provide a growing awareness of the scientific and industrial community to reduce the environmental impact by using sustainable processes. In general, the main principles of “green chemistry” are based on the design of processes aimed to reduce energy consumption and the use of eco-friendly solvents with less toxicity to the environment and human health.
  • 2.8K
  • 09 Jan 2023
Topic Review
Software Defined Networking
Software Defined Networking(SDN)has recently received much attention to address some of the enduring networking challenges. SDN’s concept is based on ideas of generalization network hardware and decoupling the network controls software from the implementation devices . SDN is a new intelligent architecture for network programmability. SDN’s main idea is to separate the control plane from the network devices, enabling the data control from a central and external software entity called an SDN controller. The Open Networking Foundation (ONF) is a non-profit consortium dedicated to the development, standardization, and commercialization of SDN for the transport and IP network layer.
  • 2.8K
  • 13 Apr 2021
Topic Review
Sacituzumab Govitecan in Breast Cancer
Sacituzumab govitecan (SG) is a third-generation antibody-drug conjugate, consisting of an anti-Trop-2 monoclonal antibody (hRS7), a hydrolyzable linker, and a cytotoxin (SN38), which inhibits topoisomerase 1. Specific pharmacological features, such as the high antibody to payload ratio, the ultra-toxic nature of SN38, and the capacity to kill surrounding tumor cells (the bystander effect), make SG a very promising drug for cancer treatment.
  • 2.8K
  • 07 Dec 2021
Topic Review
Significance of the Langat River Basin, Malaysia
Approximately 2986 river basins can be found in Malaysia, but only 189 of them are viewed as significant basins dependent on the region of the basin that is >80 km2. IRBM has many cross-cutting concerns, thus accomplishing a sound IRBM will connect practically all the Sustainable Development Goals (SDGs). Langat is the UNESCO HELP (Hydrology for the Environment, Life, and Policy) River Basin in Malaysia, and distinct in its attributes because of its flow through three distinct constituencies. Langat River Basin is among the HELP basins from the 91 river basins globally, 26 river basins in the Asia Pacific region, and 3 from the south-east Asia region.
  • 2.8K
  • 17 Jul 2023
Topic Review
Early Follicles
Early follicles' development, especially the activation of primordial follicles, is strictly modulated by a network of signaling pathways. Recent advance in ovarian physiology has been allowed the development of several therapies to improve reproductive outcomes by manipulating early folliculogenesis. Among these, in vitro activation (IVA) has been recently developed to extend the possibility of achieving genetically related offspring for patients with premature ovarian insufficiency and ovarian dysfunction. This method was established based on basic science studies of the intraovarian signaling pathways: the phosphoinositide 3-kinase (PI3K)/Akt and the Hippo signaling pathways. These two pathways were found to play crucial roles in folliculogenesis from the primordial follicle to the early antral follicle. Following the results of rodent experiments, IVA was implemented in clinical practice. There have been multiple recorded live births and ongoing pregnancies. Further investigations are essential to confirm the efficacy and safety of IVA before used widely in clinics.
  • 2.8K
  • 27 Apr 2021
Topic Review
Bioengineering Support in Low Back Pain
Low back pain (LBP) remains one of the most prevalent and disabling musculoskeletal conditions globally, with profound social, economic, and healthcare implications. The rising incidence and chronic nature of LBP highlight the need for more objective, personalized, and effective approaches to assessment and rehabilitation. In this context, bioengineering has emerged as a transformative field, offering novel tools and methodologies that enhance the understanding and management of LBP. This narrative review examines current bioengineering applications in both diagnostic and therapeutic domains. For assessment, technologies such as wearable inertial sensors, three-dimensional motion capture systems, surface electromyography, and biomechanical modeling provide real-time, quantitative insights into posture, movement patterns, and muscle activity. On the therapeutic front, innovations including robotic exoskeletons, neuromuscular electrical stimulation, virtual reality-based rehabilitation, and tele-rehabilitation platforms are increasingly being integrated into multimodal treatment protocols. These technologies support precision medicine by tailoring interventions to each patient’s biomechanical and functional profile. Furthermore, the incorporation of artificial intelligence into clinical workflows enables automated data analysis, predictive modeling, and decision support systems, while future directions such as digital twin technology hold promise for personalized simulation and outcome forecasting. While these advancements are promising, further validation in large-scale, real-world settings is required to ensure safety, efficacy, and equitable accessibility. Ultimately, bioengineering provides a multidimensional, data-driven framework that has the potential to significantly improve the assessment, rehabilitation, and overall management of LBP.
  • 2.8K
  • 25 Sep 2025
Topic Review
Cellulose-Based Polymers in Additive Manufacturing
The materials for additive manufacturing (AM) technology have grown substantially over the last few years to fulfill industrial needs. Despite that, the use of bio-based composites for improved mechanical properties and biodegradation is still not fully explored. This limits the universal expansion of AM-fabricated products due to the incompatibility of the products made from petroleum-derived resources. The development of naturally-derived polymers for AM materials is promising with the increasing number of studies in recent years owing to their biodegradation and biocompatibility. Cellulose is the most abundant biopolymer that possesses many favorable properties to be incorporated into AM materials, which have been continuously focused on in recent years. This critical review discusses the development of AM technologies and materials, cellulose-based polymers, cellulose-based three-dimensional (3D) printing filaments, liquid deposition modeling of cellulose, and four-dimensional (4D) printing of cellulose-based materials. Cellulose-based AM material applications and the limitations with future developments are also reviewed.
  • 2.8K
  • 02 Sep 2020
Topic Review
SDN-IP and the SoDIP6 Network
     SDN-IP is an application developed to implement routing between SDN and legacy networks. It enables communication over a multi-autonomous system (multi-AS) within the SDN and legacy networks. SDN-IP is implemented over ONOS to integrate SDN and legacy networks in terms of routing and interoperability so that service providers can have a gradual migration by smoothly integrating SDN with the legacy networks.        SoDIP6 network is a complete network and server systems operate with IPv6 addressing and routing over Software-defined network environment, in which the data plane forwarding devices enabled with IPv6 packet communications, are controlled and managed by logically centralized SDN controller
  • 2.8K
  • 10 Sep 2020
Topic Review
Glutathione
Glutathione refers to the small molecule protein consisting of three amino acids - glycine, cysteine, and glutamine.
  • 2.8K
  • 01 Feb 2021
Topic Review
Grain Number per Panicle
Rice grain yield is a complex trait determined by three components: panicle number, grain number per panicle (GNPP) and grain weight. GNPP is the major contributor to grain yield and is crucial for its improvement. GNPP is determined by a series of physiological and biochemical steps, including inflorescence development, formation of rachis branches such as primary rachis branches and secondary rachis branches, and spikelet specialisation (lateral and terminal spikelets).
  • 2.8K
  • 06 Apr 2021
Topic Review
Additive Manufacturing of High Entropy Alloys
Alloying has been very common practice in materials engineering to fabricate metals of desirable properties for specific applications. Traditionally, a small amount of the desired material is added to the principal metal. However, a new alloying technique emerged in 2004 with the concept of adding several principal elements in or near equi-atomic concentrations. These are popularly known as high entropy alloys (HEAs) which can have a wide composition range.
  • 2.8K
  • 15 Mar 2022
Topic Review
Applications of Social Robotics
Social robots are being proposed in telepresence, medicine, education, entertainment, assistance, and other domains. Benefiting from their information acquisition and processing, and actuation capacities, social robots are conceived to either replace or assist humans in daily social interaction contexts.
  • 2.8K
  • 04 Aug 2022
Topic Review
Classification and Diagnosis of Acute Pancreatitis
The pancreas is a glandular organ that is responsible for the proper functioning of the digestive and endocrine systems, and therefore, it affects the condition of the entire body. Consequently, it is important to effectively diagnose and treat diseases of this organ. According to clinicians, pancreatitis—a common disease affecting the pancreas—is one of the most complicated and demanding diseases of the abdomen. The classification of pancreatitis is based on clinical, morphologic, and histologic criteria. Medical doctors distinguish, inter alia, acute pancreatitis (AP), the most common causes of which are gallstone migration and alcohol abuse.
  • 2.8K
  • 30 Aug 2022
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