Your browser does not fully support modern features. Please upgrade for a smoother experience.
Subject:
All Disciplines Arts & Humanities Biology & Life Sciences Business & Economics Chemistry & Materials Science Computer Science & Mathematics Engineering Environmental & Earth Sciences Medicine & Pharmacology Physical Sciences Public Health & Healthcare Social Sciences
Sort by:
Most Viewed Latest Alphabetical (A-Z) Alphabetical (Z-A)
Filter:
All Topic Review Biography Peer Reviewed Entry Video Entry
Topic Review
Chromosome 5
Humans normally have 46 chromosomes in each cell, divided into 23 pairs. Two copies of chromosome 5, one copy inherited from each parent, form one of the pairs.
  • 1.1K
  • 24 Dec 2020
Topic Review
Kallmann Syndrome
Kallmann syndrome is a condition characterized by delayed or absent puberty and an impaired sense of smell.
  • 1.1K
  • 23 Dec 2020
Topic Review
Non-alcoholic Fatty Liver Disease
Non-alcoholic fatty liver disease (NAFLD) is a buildup of excessive fat in the liver that can lead to liver damage resembling the damage caused by alcohol abuse, but that occurs in people who do not drink heavily. The liver is a part of the digestive system that helps break down food, store energy, and remove waste products, including toxins. The liver normally contains some fat; an individual is considered to have a fatty liver (hepatic steatosis) if the liver contains more than 5 to 10 percent fat.
  • 1.1K
  • 04 Jan 2021
Topic Review
Mainzer-Saldino Syndrome
Mainzer-Saldino syndrome is a disorder characterized by kidney disease, eye problems, and skeletal abnormalities.
  • 1.1K
  • 23 Dec 2020
Topic Review
MT-ND6 Gene
mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 6
  • 1.1K
  • 23 Dec 2020
Topic Review
LDLR Gene
Low density lipoprotein receptor
  • 1.1K
  • 23 Dec 2020
Topic Review
Oculocutaneous Albinism
Oculocutaneous albinism is a group of conditions that affect coloring (pigmentation) of the skin, hair, and eyes.
  • 1.1K
  • 24 Dec 2020
Topic Review
Autoimmune Addison Disease
Autoimmune Addison disease affects the function of the adrenal glands, which are small hormone-producing glands located on top of each kidney. It is classified as an autoimmune disorder because it results from a malfunctioning immune system that attacks the adrenal glands. As a result, the production of several hormones is disrupted, which affects many body systems.
  • 1.1K
  • 24 Dec 2020
Topic Review
FGA Gene
Fibrinogen alpha chain
  • 1.1K
  • 25 Dec 2020
Topic Review
Atopic Dermatitis
Atopic dermatitis (also known as atopic eczema) is a disorder characterized by inflammation of the skin (dermatitis). The condition usually begins in early infancy, and it often disappears before adolescence. However, in some affected individuals the condition continues into adulthood; in others, it does not begin until adulthood. Hallmarks of atopic dermatitis include dry, itchy skin and red rashes that come and go. The rashes can occur on any part of the body, although the pattern tends to be different at different ages. In affected infants, the rashes commonly occur on the face, scalp, hands, and feet. In children, the rashes are usually found in the bend of the elbows and knees and on the front of the neck. In adolescents and adults, the rashes typically occur on the wrists, ankles, and eyelids in addition to the bend of the elbows and knees. Scratching the itchy skin can lead to oozing and crusting of the rashes and thickening and hardening (lichenification) of the skin. The itchiness can be so severe as to disturb sleep and impair a person's quality of life.
  • 1.1K
  • 31 Dec 2020
Topic Review
Spondylothoracic Dysostosis
Spondylothoracic dysostosis is a condition characterized by malformation of the bones of the spine and ribs.
  • 1.1K
  • 23 Dec 2020
Topic Review
X-linked Adrenoleukodystrophy
X-linked adrenoleukodystrophy is a genetic disorder that occurs primarily in males. It mainly affects the nervous system and the adrenal glands, which are small glands located on top of each kidney. In this disorder, the fatty covering (myelin) that insulates nerves in the brain and spinal cord is prone to deterioration (demyelination), which reduces the ability of the nerves to relay information to the brain. In addition, damage to the outer layer of the adrenal glands (adrenal cortex) causes a shortage of certain hormones (adrenocortical insufficiency). Adrenocortical insufficiency may cause weakness, weight loss, skin changes, vomiting, and coma.  
  • 1.1K
  • 24 Dec 2020
Topic Review
Usher Syndrome
Usher syndrome is a condition characterized by partial or total hearing loss and vision loss that worsens over time.
  • 1.1K
  • 23 Dec 2020
Topic Review
LncRNA in Colorectal Cancer
Colorectal cancer is the third most common cause of cancer mortality worldwide, and one of the current hot topics in this field is the identification of markers for identifying patients with high probability of relapse, which may benefit from adjuvant chemotherapy in stage II. In this sense long noncoding RNAs are a promising source of novel cancer biomarkers and therapeutic targets, although to robustly assess their gene expression levels is challenging due to their low expression. We present a protocol (hereafter referred as CoLong design) which couples target enrichment and RNA-seq that allows transcriptomics studies of lncRNAs in formalin-fixed paraffin embedded (FFPE) tissue samples. We show that our new approach alllows to efficiently detect differences in gene expression and somatic mutations in lncRNAs, and we propose several lncRNAs as potential candidates for colorectal cancer. This new approach could represent a promising avenue that would reduce costs and enable more efficient translational research.
  • 1.1K
  • 27 Oct 2020
Topic Review
MPL Gene
MPL proto-oncogene, thrombopoietin receptor
  • 1.1K
  • 23 Dec 2020
Topic Review
Fragile X Syndrome
Fragile X syndrome is a genetic condition that causes a range of developmental problems including learning disabilities and cognitive impairment. Usually, males are more severely affected by this disorder than females.
  • 1.1K
  • 25 Dec 2020
Topic Review
Pilomatricoma
Pilomatricoma, also known as pilomatrixoma, is a type of noncancerous (benign) skin tumor associated with hair follicles.
  • 1.1K
  • 24 Dec 2020
Topic Review
ALX4 Gene
ALX homeobox 4. The ALX4 gene provides instructions for making a member of the homeobox protein family.
  • 1.1K
  • 24 Dec 2020
Topic Review
Russell-Silver Syndrome
Russell-Silver syndrome is a growth disorder characterized by slow growth before and after birth.
  • 1.1K
  • 24 Dec 2020
Topic Review
AKT1 Gene
AKT serine/threonine kinase 1
  • 1.1K
  • 24 Dec 2020
  • Page
  • of
  • 135
Featured Entry Collections
>>

Featured Reprints

>>
Encyclopedia of Digital Society, Industry 5.0 and Smart City
Encyclopedia of Engineering
Encyclopedia of Social Sciences
Encyclopedia of Medieval Royal Iconography
Academic Video Service
Feedback