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Topic Review
ZIF-8 for Heavy-Metal Removal
Zeolitic imidazolate framework (ZIF-8), a type of MOF used for heavy-metal removal in aqueous solutions, as well as its application, adsorption mechanisms, and the factors that influence its adsorption mechanism.
  • 3.3K
  • 28 Jan 2021
Topic Review
Comfort Food
Comfort food is food that provides a nostalgic or sentimental value to someone, and may be characterized by its high caloric nature, high carbohydrate level, or simple preparation. The nostalgia may be specific to an individual, or it may apply to a specific culture.
  • 3.3K
  • 24 Nov 2022
Topic Review
Malaria
Malaria is a severe disease caused by parasites of the genus Plasmodium, which is transmitted to humans by a bite of an infected female mosquito of the species Anopheles. Malaria remains the leading cause of mortality around the world, and early diagnosis and fast-acting treatment prevent unwanted outcomes. It is the most common disease in Africa and some countries of Asia, while in the developed world malaria occurs as imported from endemic areas. The sweet sagewort plant was used as early as the second century BC to treat malaria fever in China. Much later, quinine started being used as an antimalaria drug. A global battle against malaria started in 1955. The World Health Organization carries out a malaria control program on a global scale, focusing on local strengthening of primary health care, early diagnosis of the disease, timely treatment, and disease prevention. Globally, the burden of malaria is lower than ten years ago. However, in the last few years, there has been an increase in the number of malaria cases around the world. It is moving towards targets established by the WHO, but that progress has slowed down.
  • 3.3K
  • 17 Feb 2021
Topic Review
CBT-E for Eating Disorders
Enhanced cognitive behaviour therapy, also known as CBT-E, is a “transdiagnostic” psychological treatment for all forms of eating disorder including anorexia nervosa, bulimia nervosa, binge eating disorder and other similar states. CBT-E is the only treatment recommended by the National Institute for Health and Care Excellence (NICE) for all the forms of eating disorders both for adults and adolescents
  • 3.3K
  • 27 Oct 2020
Topic Review
Biodegradation of Polyethylene Terephthalate
Polyethylene terephthalate (PET) is a widely used plastic that is polymerized by terephthalic acid (TPA) and ethylene glycol (EG).
  • 3.3K
  • 30 Dec 2021
Topic Review
Dialysis
In medicine, dialysis (from Greek διάλυσις, dialysis, "dissolution"; from διά, dia, "through", and λύσις, lysis, "loosening or splitting") is the process of removing excess water, solutes, and toxins from the blood in people whose kidneys can no longer perform these functions naturally. This is referred to as renal replacement therapy. The first successful dialysis was performed in 1943. Dialysis may need to be initiated when there is a sudden rapid loss of kidney function, known as acute kidney injury (previously called acute renal failure), or when a gradual decline in kidney function, chronic kidney disease, reaches stage 5. Stage 5 chronic renal failure is reached when the glomerular filtration rate is 10–15% of normal, creatinine clearance is less than 10 mL per minute and uremia is present. Dialysis is used as a temporary measure in either acute kidney injury or in those awaiting kidney transplant and as a permanent measure in those for whom a transplant is not indicated or not possible. In Australia, Canada, the United Kingdom, and the United States, dialysis is paid for by the government for those who are eligible. In research laboratories, dialysis technique can also be used to separate molecules based on their size. Additionally, it can be used to balance buffer between a sample and the solution "dialysis bath" or "dialysate" that the sample is in. For dialysis in a laboratory, a tubular semipermeable membrane made of cellulose acetate or nitrocellulose is used. Pore size is varied according to the size separation required with larger pore sizes allowing larger molecules to pass through the membrane. Solvents, ions and buffer can diffuse easily across the semipermeable membrane, but larger molecules are unable to pass through the pores. This can be used to purify proteins of interest from a complex mixture by removing smaller proteins and molecules.
  • 3.3K
  • 07 Nov 2022
Topic Review
Nucleation in Polymer Crystallization
Nucleation plays a vital role in polymer crystallization, in which chain connectivity and thus the multiple length and time scales make crystal nucleation of polymer chains an interesting but complex subject. Though the topic has been intensively studied in the past decades, there are still many open questions to answer. The final properties of semicrystalline polymer materials are affected by all of the following: the starting melt, paths of nucleation, organization of lamellar crystals and evolution of the final crystalline structures. In this viewpoint, we attempt to discuss some of the remaining open questions and corresponding concepts: non-equilibrated polymers, self-induced nucleation, microscopic kinetics of different processes, metastability of polymer lamellar crystals, hierarchical order and cooperativity involved in nucleation, etc. Addressing these open questions through a combination of novel concepts, new theories and advanced approaches provides a deeper understanding of the multifaceted process of crystal nucleation of polymers.
  • 3.3K
  • 25 Jun 2021
Topic Review
Novichok Agent
A Novichok agent (Russian: Новичо́к, "newcomer", "novice", "newbie") is a group of nerve agents, some of which are binary chemical weapons. The agents were developed at the GosNIIOKhT state chemical research institute by the Soviet Union and Russia between 1971 and 1993.[lower-alpha 1] Some Novichok agents at STP are solids while others are liquids. It is thought that dispersal for the solids is possible by ultrafine powder. Russian scientists who developed the nerve agents claim they are the deadliest ever made, with some variants possibly five to eight times more potent than VX, and others up to ten times more potent than soman. As well as Russia, Novichok agents have been known to be produced in Iran. In the 21st century, Novichok agents came to public attention after they were used to poison opponents of the Russian government, including the Skripals and two others in Amesbury, UK (2018) and Alexei Navalny (2020), but civil poisonings with this substance have been known since at least 1995. In November 2019, the Organisation for the Prohibition of Chemical Weapons (OPCW), which is the executive body for the Chemical Weapons Convention (CWC), added the Novichok agents to "list of controlled substances" of the CWC "in one of the first major changes to the treaty since it was agreed in the 1990s" in response to the 2018 poisonings in the UK.
  • 3.3K
  • 11 Nov 2022
Topic Review
Vitamin C Deficiency
Vitamin C is an essential nutrient that must be obtained through the diet in adequate amounts to prevent hypovitaminosis C, deficiency and its consequences—including the potentially fatal deficiency disease scurvy. Global vitamin C status and prevalence of deficiency has not previously been reported, despite vitamin C’s pleiotropic roles in both non-communicable and communicable disease. This entry highlights the global literature on vitamin C status and the prevalence of hypovitaminosis C and deficiency. Related dietary intake is reported if assessed in the studies. Overall, the entry illustrates the shortage of high quality epidemiological studies of vitamin C status in many countries, particularly low- and middle-income countries. The available evidence indicates that vitamin C hypovitaminosis and deficiency is common in low- and middle-income countries and not uncommon in high income settings. 
  • 3.3K
  • 27 Jul 2020
Topic Review
Determination of KISCC by The Circumferential Notch Tensile
Stress corrosion cracking (SCC) is a vexing problem for load-bearing equipment operating in a corrosive environment in various industries, such as aerospace, chemical and mineral processing, civil structures, bioimplants, energy generation etc. For safe operation, effective maintenance and life prediction of such equipment, reliable design data on SCC (such as threshold stress intensity for SCC, i.e., KISCC) are invaluable. Generating reliable KISCC data invariably requires a large number of tests. Traditional techniques can be prohibitively expensive. Circumfrential notch tensile testing is a relatively recent, much simpler and cost-effective approach to generating accurate and reliable KISCC data.
  • 3.3K
  • 12 Nov 2021
Topic Review
Forensic Palynology
Forensic palynology is a subdiscipline of palynology (the study of pollen grains, spores, etc.), that aims to prove or disprove a relationship among objects, people, and places that may pertain to both criminal and civil cases. Pollen can reveal where a person or object has been, because regions of the world, countries, and even different parts of a single garden will have a distinctive pollen assemblage. Pollen evidence can also reveal the season in which a particular object picked up the pollen. Palynology is the study of palynomorphs - microscopic structures of both animal and plant origin that are resistant to decay. This includes spermatophyte pollen, as well as spores (fungi, bryophytes, and ferns), dinoflagellates, and various other organic microorganisms - both living and fossilized. There are a variety of ways in which the study of these microscopic, walled particles can be applied to criminal forensics. In areas such as New Zealand, where the demand for this field is high, forensic palynology has been used as evidence in many different case types that range anywhere from non-violent to extremely violent crimes. Pollen has been used to trace activity at mass graves in Bosnia, pinpoint the scene of a crime, and catch a burglar who brushed against a Hypericum bush during a crime. Because pollen has distinct morphology and is relatively indestructible, it is likely to adhere to a variety of surfaces often without notice and has even become a part of ongoing research into forensic bullet coatings.
  • 3.3K
  • 21 Nov 2022
Topic Review
Polyphenols and omega-3 as nutriceuticals
The adequate combination of the well-recognized individual nutraceutical properties of polyphenols and omega-3 polyunsaturated fatty acids from fish oils (eicosapentaenoic and docosahexaenoic acids), particularlly their single antioxidant and anti-inflammatory properties, may offer a powerful tool for the design of successfully nutritional interventions for the prevention and palliation of a plethora of human diseases, often diet-related, whose etiology and progression are characterized by redox homeostasis disturbances and a low-grade of chronic inflammation. However, the certain mechanisms behind their biological activities, in vivo interaction (both between them and other food compounds), and their optimal doses and consumption are not well-known yet. Therefore, we review here the recent accumulated evidence in both preclinical and clinical trials, of the cooperative action between polyphenols and fish oils as nutraceuticals on human health, focusing on the mechanisms and pathways described and the effects reported. The final objective is to provide useful information for developing effective strategies of personalized nutrition based on the combined used of these bioactive food compounds.
  • 3.3K
  • 11 Jul 2021
Topic Review
Sunscreens and UV Protection
Excessive UV (ultraviolet) radiation exposure is harmful to skin cells since sunburn is accompanied by oxidative burst, leading to a rapid increase in skin cancer. However, the insufficient UV photoprotection of approved sunscreens and the negative impact of their compositions on ecosystems and human health makes the utility of sunscreen a questionable recommendation. Therefore, discovering UV filters with significant antioxidant activity and improved topical performance and photostability is an urgent need.
  • 3.3K
  • 17 Mar 2023
Topic Review
Rheumatoid Arthritis and Prevotella copri
Rheumatoid arthritis (RA) is a debilitating disease caused by several factors, which have only been partially identified. Globally approximately 0.24% of people are affected by RA, with women being more affected than men. The gastrointestinal tract is an essential getaway for the intake of favorable and harmful microbes and their metabolites through food and drinks. The imbalance of gut microbiota can cause gut dysbiosis, which is caused by an abundance of Prevotella copri. In recent years there have been reports citing Prevotella copri as the causative organism for RA, but there also have been reports contradicting the above findings. This topical review attempts to bring the two viewpoints together and find common ground for a rational hypothesis.
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  • 30 Jul 2021
Topic Review
CHCP (DOS Command)
This article presents a list of commands used by DOS operating systems, especially as used on x86-based IBM PC compatibles (PCs). Other DOS operating systems are not part of the scope of this list. In DOS, many standard system commands were provided for common tasks such as listing files on a disk or moving files. Some commands were built into the command interpreter, others existed as external commands on disk. Over the several generations of DOS, commands were added for the additional functions of the operating system. In the current Microsoft Windows operating system, a text-mode command prompt window, cmd.exe, can still be used.
  • 3.3K
  • 30 Nov 2022
Topic Review
Enzyme Immobilization Techniques
Researchers have explored the technique of enzyme immobilization as a means to overcome limitations that free enzymes encounter, including reduced performance, high costs, and impracticality for large-scale applications. Enzymatic treatment offers a sustainable and eco-friendly alternative to conventional physicochemical treatment methods, such as adsorption, coagulation, and advanced oxidation processes. Free enzymes are biodegradable, highly efficient, and selective biological catalysts that can operate under mild conditions, thus reducing energy consumption and minimizing the generation of harmful byproducts.
  • 3.3K
  • 07 Sep 2023
Topic Review
Resonant cavity antennas technology
       Resonant cavity antennas (RCAs) are suitable candidates to achieve high directivity with a low-cost and easy fabrication process. The stable functionality of the RCAs over different frequency bands, as well as, their pattern reconfigurability make them an attractive antenna structure for the next-generation wireless communication systems, i.e., fifth-generation (5G). The variety of designs and analytical techniques regarding the main radiator and partially reflective surface (PRS) configurations allow dramatic progress and advances in the area of RCAs. Adding different functionalities in a single structure by using additional layers is one appealing feature of the RCA structures, which has opened the various fields of studies toward 5G applications. This paper reviews the recent advances on the RCAs along with the analytical methods, and various capabilities that make them suitable to be used in 5G communication systems. 
  • 3.3K
  • 27 Aug 2020
Topic Review Peer Reviewed
COVID-19 Pandemic as a Transitional Event: From the Perspective of the Transition Theory
The COVID-19 pandemic has affected every aspect of people’s lives across the globe. It is also unique in the way it changed their lives. In this entry, a framework, the Transition Theory, is outlined, which is used to interpret the transitional properties of this pandemic, the ways it differs from other transitional events, and how it impacts the lives and well-being of the individuals. The prediction is that people might consider the pandemic as an important life transition event only if there is a little similarity between their pre-pandemic and post-pandemic lives. Individual differences also need to be considered as those whose lives have been directly affected by the pandemic experience a greater COVID-related change (e.g., job loss vs. no job loss). Lastly, the transitional impact of the pandemic might have a strong link with people’s mental outcomes. These notions call for a longitudinal approach to get an accurate understanding of the pandemic experience while this world-changing event unfolds rather than in retrospect.
  • 3.3K
  • 21 Sep 2022
Topic Review
Alder Lake (Microprocessor)
Alder Lake is Intel's codename for the 12th generation of Intel Core processors based on a hybrid architecture utilizing Golden Cove high-performance cores and Gracemont power-efficient cores. It is fabricated using Intel's Intel 7 process, previously referred to as Intel 10 nm Enhanced SuperFin (10ESF). Intel officially announced 12th Gen Intel Core CPUs on October 27, 2021. Intel officially announced 12th Gen Intel Core mobile CPUs and non-K series desktop CPUs on January 4, 2022. Intel officially announced the launch of Alder Lake-P and -U series on February 23, 2022.
  • 3.3K
  • 26 Oct 2022
Topic Review
Mechanisms and Classification of Bioactive Peptides
Bioactive peptides have gained significant attention in the cosmetic industry due to their potential in enhancing skin health and beauty. These small protein fragments exhibit various biological activities, such as antioxidant, anti-aging, anti-inflammatory, and antimicrobial activities, making them ideal ingredients for cosmetic formulations. These bioactive peptides are classified into four categories: signal, carrier, neurotransmitter-inhibitory, and enzyme-inhibitory peptides. 
  • 3.3K
  • 18 Aug 2023
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