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Topic Review
Air Travel
The first aircraft at the beginning of the 20th century had too weak engines to carry passengers. Air travel that time mainly took place in large airships. The first commercial flight took place on January 1st, 1914, across Tampa Bay, Florida, with one paying passenger. The first regular passenger air transport took place in Germany, between Berlin and Weimar, from 1919. The 1920s brought fast growth of passenger aviation. In 1932, the first serial production of aircraft for passenger air travel started. However, at that time, transatlantic passenger flights were still only performed by airships. Jet aircraft replaced propeller aircraft in the 1950s. Now there are eight million commercial flights every year (status: June 2011). The crew of an airplane consists of the captain, the first, second and third officer, the flight attendants, the flight engineer, the loadmaster, the pilot and the purser. About eight million people fly every day, yielding 3.1 billion passengers in air travel in 2013. Besides people and their luggage, cargo is transported, about 140,000 tons every day, which is equivalent to 50 million tons per year. There are nearly 60 million jobs in air travel; the global turnover of the airline industry is more than 700 billion USD, with about 2.6% net profit. International aviation reached a new record in 2010 with more than 30.5 million commercial flights. 35% of the total departures in 2010 took place in North America, 25% in Asia, 24% in Europe, 10% in Latin America and the Caribbean, 3% in Oceania and 3% in Africa. Fastest growth is in Asia Pacific, Latin America, the Caribbean, Africa and the Middle East. Until 2030, an increase of the number of commercial flights to 52 million is estimated.
  • 3.2K
  • 22 May 2024
Topic Review
Oldest People
This is a list of tables of the oldest people in the world in ordinal ranks. To avoid including false or unconfirmed claims of extreme old age, names here are restricted to those people whose ages have been validated by an international body that specifically deals in longevity research, such as the Gerontology Research Group (GRG) or Guinness World Records (GWR), and others who have otherwise been reliably sourced. According to this criterion, the longest human lifespan is that of Jeanne Calment of France (1875–1997), who lived to the age of 122 years, 164 days. She met Vincent van Gogh when she was 12 or 13. She received news media attention in 1985, after turning 110. Subsequent investigation found documentation for Calment's age, beyond any reasonable question, in the records of her native city, Arles, France. More evidence of Calment's lifespan has been produced than for any other supercentenarian, such that her case serves as an archetype in the methodology for verifying the ages of the world's oldest people. As women live longer than men on average, combined records for both sexes are predominated by women. The longest undisputed lifespan for a man is that of Jiroemon Kimura of Japan (1897–2013), who died at age 116 years, 54 days. Since the death of 117-year-old Chiyo Miyako of Japan on 22 July 2018, 115-year-old Kane Tanaka, also of Japan, born 2 January 1903, is the oldest living person in the world whose age has been documented. Since the death of 113-year-old Francisco Núñez Olivera of Spain on 29 January 2018, 113-year-old Masazō Nonaka of Japan, born 25 July 1905, is the world's oldest verified living man.
  • 3.2K
  • 30 Nov 2022
Topic Review
Ganoderma Triterpenoids and Their Bioactivities
Ganoderma has been used as a traditional medicine in Asian countries to prevent and treat various diseases. Numerous publications are stating that Ganoderma species have a variety of beneficial medicinal properties, and investigations on different metabolic regulations of Ganoderma species, extracts or isolated compounds have been performed both in vitro and in vivo.
  • 3.2K
  • 11 Jan 2023
Topic Review
Determination of KISCC by The Circumferential Notch Tensile
Stress corrosion cracking (SCC) is a vexing problem for load-bearing equipment operating in a corrosive environment in various industries, such as aerospace, chemical and mineral processing, civil structures, bioimplants, energy generation etc. For safe operation, effective maintenance and life prediction of such equipment, reliable design data on SCC (such as threshold stress intensity for SCC, i.e., KISCC) are invaluable. Generating reliable KISCC data invariably requires a large number of tests. Traditional techniques can be prohibitively expensive. Circumfrential notch tensile testing is a relatively recent, much simpler and cost-effective approach to generating accurate and reliable KISCC data.
  • 3.2K
  • 12 Nov 2021
Topic Review
Polyphenols and omega-3 as nutriceuticals
The adequate combination of the well-recognized individual nutraceutical properties of polyphenols and omega-3 polyunsaturated fatty acids from fish oils (eicosapentaenoic and docosahexaenoic acids), particularlly their single antioxidant and anti-inflammatory properties, may offer a powerful tool for the design of successfully nutritional interventions for the prevention and palliation of a plethora of human diseases, often diet-related, whose etiology and progression are characterized by redox homeostasis disturbances and a low-grade of chronic inflammation. However, the certain mechanisms behind their biological activities, in vivo interaction (both between them and other food compounds), and their optimal doses and consumption are not well-known yet. Therefore, we review here the recent accumulated evidence in both preclinical and clinical trials, of the cooperative action between polyphenols and fish oils as nutraceuticals on human health, focusing on the mechanisms and pathways described and the effects reported. The final objective is to provide useful information for developing effective strategies of personalized nutrition based on the combined used of these bioactive food compounds.
  • 3.2K
  • 11 Jul 2021
Topic Review
Turn (Geometry)
A turn is a unit of plane angle measurement equal to 2π radians, 360 degrees or 400 gradians. A turn is also referred to as a cycle (abbreviated cyc), revolution (abbreviated rev), complete rotation (abbreviated rot) or full circle. Subdivisions of a turn include half turns, quarter turns, centiturns, milliturns, points, etc.
  • 3.2K
  • 22 Nov 2022
Topic Review
Self-healing Polymeric Materials
The mechanism of self-healing, which includes the extrinsic and intrinsic approaches for each of the applications, is examined. The extrinsic mechanism involves the introduction of external healing agents such as microcapsules and vascular networks into the system. Meanwhile, the intrinsic mechanism refers to the inherent reversibility of the molecular interaction of the polymer matrix, which is triggered by the external stimuli. Both self-healing mechanisms have shown a significant impact on the cracked properties of the damaged sites.
  • 3.2K
  • 21 Apr 2021
Topic Review
DNA Microarrays
Early disease detection using microarray data is vital for prompt and efficient treatment. However, the intricate nature of these data and the ongoing need for more precise interpretation techniques make it a persistently active research field. Numerous gene expression datasets are publicly available, containing microarray data that reflect the activation status of thousands of genes in patients who may have a specific disease. ThesGene expression microarrays, also known as DNA microarrays, are laboratory tools used to measure the expression levels of thousands of genes simultaneously, thus providing a snapshot of the cellular function (for technical details.e datasets encompass a vast number of genes, resulting in high-dimensional feature vectors that present significant challenges for human analysis. 
  • 3.2K
  • 24 Oct 2023
Topic Review
Wire Arc Additive Manufacturing Process
Wire arc additive manufacturing (WAAM) is an emerging and promising technology for producing medium-to-large-scale metallic components/structures for different industries, i.e., aerospace, automotive, shipbuilding, etc. It is now a feasible alternative to traditional manufacturing processes due to its shorter lead time, low material waste, and cost effectiveness. WAAM has been widely used to produce components using different materials, including copper-based alloy wires, in the past decades. 
  • 3.2K
  • 19 Jun 2023
Topic Review
Optical Tweezers
Optical tweezers is a very well-established technique that has developed into a standard tool for trapping and manipulating micron and submicron particles with great success in the last decades. Under tight focusing of a laser beam the optical forces that appear around the focus spot can be both repulsive (scattering force) and attractive (gradient force) towards a particle with higher refractive index than its surroundings. By proper control of these two forces a stable potential can be achieved where a particle can be trapped and manipulated in space. The ability to manipulate micro- and nanoscale matter according to our needs has opened great avenues to a variety of research areas.
  • 3.2K
  • 19 Aug 2020
Topic Review
Music and Obsessive-Compulsive Disorder
Obsessive-compulsive disorder (OCD) is a severe psychiatric disorder, which can be associated with music-related symptoms. Music may also be used as an adjunct treatment for OCD. Patients with OCD might benefit from music therapy, which includes listening to music.
  • 3.2K
  • 22 Nov 2021
Topic Review
Surfaces on Sprint Performance
The main function of a sport surface is to ensure safety and adequate player performance during physical exercise practice. 
  • 3.2K
  • 29 Apr 2021
Topic Review
Alder Lake (Microprocessor)
Alder Lake is Intel's codename for the 12th generation of Intel Core processors based on a hybrid architecture utilizing Golden Cove high-performance cores and Gracemont power-efficient cores. It is fabricated using Intel's Intel 7 process, previously referred to as Intel 10 nm Enhanced SuperFin (10ESF). Intel officially announced 12th Gen Intel Core CPUs on October 27, 2021. Intel officially announced 12th Gen Intel Core mobile CPUs and non-K series desktop CPUs on January 4, 2022. Intel officially announced the launch of Alder Lake-P and -U series on February 23, 2022.
  • 3.2K
  • 26 Oct 2022
Topic Review
Rheumatoid Arthritis and Prevotella copri
Rheumatoid arthritis (RA) is a debilitating disease caused by several factors, which have only been partially identified. Globally approximately 0.24% of people are affected by RA, with women being more affected than men. The gastrointestinal tract is an essential getaway for the intake of favorable and harmful microbes and their metabolites through food and drinks. The imbalance of gut microbiota can cause gut dysbiosis, which is caused by an abundance of Prevotella copri. In recent years there have been reports citing Prevotella copri as the causative organism for RA, but there also have been reports contradicting the above findings. This topical review attempts to bring the two viewpoints together and find common ground for a rational hypothesis.
  • 3.2K
  • 30 Jul 2021
Topic Review
Glossitis Areata Exfoliativa
Geographic tongue, also known by several other terms, is a condition of the mucous membrane of the tongue, usually on the dorsal surface. It is a common condition, affecting approximately 2–3% of the general population. It is characterized by areas of smooth, red depapillation (loss of lingual papillae) which migrate over time. The name comes from the map-like appearance of the tongue, with the patches resembling the islands of an archipelago. The cause is unknown, but the condition is entirely benign (importantly, it does not represent oral cancer), and there is no curative treatment. Uncommonly, geographic tongue may cause a burning sensation on the tongue, for which various treatments have been described with little formal evidence of efficacy.
  • 3.2K
  • 24 Oct 2022
Topic Review
Plug-In Electric Vehicles in the Netherlands
The adoption of plug-in electric vehicles in the Netherlands is actively supported by the Dutch government through the exemption of the registration fee and road taxes. These purchase incentives have been adjusted over time. Considering the potential of plug-in electric vehicles in the country due to its relative small size and geography, the Dutch government set a target of 15,000 to 20,000 electric vehicles with three or more wheels on the roads in 2015; 200,000 vehicles in 2020; and 1 million vehicles in 2025. The first two targets were achieved two years earlier than planned. The Dutch plug-in market was dominated by plug-in hybrids until 2016, when the tax rules changed after it became apparent many users rarely used the electric motors and only bought the cars for their tax advantage. In 2019, plug-in electric passenger cars had a market share of 14.9%, and rose to 24.6% in 2020, with battery electric vehicles dominating sales in both years. (As of December 2020), there were 297,380 highway-legal light-duty plug-in electric vehicles on the road in the Netherlands, consisting of 182,481 fully electric cars, 108,652 plug-in hybrids, and 6,247 all-electric light utility vans. (As of December 2012), the Netherlands was the country with the highest ratio of slow charging points to electric vehicles (EVSE/EV), with a ratio of more than 0.50, while the U.S had a slow EVSE/EV ratio of 0.20. The Netherlands' mix of slow and fast chargers has allowed it to become the country with the highest number of charging point per capita in the world. (As of December 2016), there were 11,768 public slow charging points available 24/7, 14,320 slow charging point with limited public access, 612 public and semi-public fast charging points, and over 72,000 private charging points.
  • 3.2K
  • 10 Nov 2022
Topic Review
Alkylimidazoles
Alkylimidazoles have good complexing properties, also they are  cheap so can be successfully used in the separation of metal ions from aqueous solutions.
  • 3.2K
  • 16 Dec 2020
Topic Review
Pyocyanin
Pyocyanin is a blue pigment synthesized by about 95% of the strains of Pseudomonas aeruginosa.
  • 3.2K
  • 02 Mar 2021
Topic Review
Light detection and ranging (LiDAR)
Light Detection and Ranging (LiDAR) is a 3D imaging technique, widely used in many applications such as augmented reality, automotive, machine vision, spacecraft navigation and landing. Achieving long-ranges and high-speed, most of all in outdoor applications with strong solar background illumination, are challenging requirements.
  • 3.2K
  • 23 Jun 2021
Topic Review
Potential Effects of Fasting in SARS-CoV-2 Infection
Intermittent fasting is a potential complementary therapy to vaccination and antiviral therapies that not only impacts chronic disease risk but also has good evidence of an impact on infectious diseases such as COVID-19. Intermittent fasting should improve the immune response of and reduce acute hyperinflammation for unvaccinated people, strengthen immunity between vaccinations for vaccinated people, and prolong the length of time a vaccinated person can go before receiving a subsequent booster dose of the SARS-CoV-2 vaccine. A set of at least 10 biological mechanisms may be impacted by intermittent fasting in the human physiological response to SARS-CoV-2 that may reduce the severity of COVID-19 outcomes. For example, by boosting autophagy, fasting may aid the immune system to identify silently infected cells via increased degradation of viral proteins and through antigen presentation to natural killer cells and cytotoxic T cells. Intermittent fasting may also provide a constellation of mechanisms that empower a damaged human immune system to repair itself and to hunt down residual SARS-CoV-2 virus that is hiding from it in the context of both acute infection and post-acute sequelae of COVID-19. Furthermore, fasting adds no financial cost to a care plan and, when practiced safely, is available to most adults regardless of education, income, location, or ancestry. Clinical trials of intermittent fasting for reduction of COVID-19 severity are needed.
  • 3.2K
  • 06 Jan 2023
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