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Topic Review
Ultrasound Examination in Nail Apparatus Assessment in Psoriasis
The assessment of psoriatic nail changes in everyday practice is based exclusively on clinical symptoms that do not reflect the entire disease process in the nail apparatus. The use of imaging methods, especially widely available and inexpensive ultrasonography, creates the possibility of additional revealing and assessing grayscale of morphological changes of the ventral nail plate, nail bed, and matrix, as well as the attachment of the finger extensor tendon to the distal phalanx. What is more, it enables the assessment of inflammation severity in the power Doppler technique. A qualitative classification of nail plate morphological changes corresponding to the severity of psoriatic nail changes has been developed so far and attempts are being made to develop a quantitative method to assess not only the presence of changes but also the severity of inflammation. 
  • 3.3K
  • 20 May 2022
Topic Review
Permeation Enhancers of Hormones Penetration through the Skin
Hormones have attracted considerable interest in recent years due to their potential use in treatment of many diseases. Their ability to have a multidirectional effect leads to searching for new and increasingly effective drugs and therapies. Limitations in formulating drug forms containing hormones are mainly due to their low enzymatic stability, short half-life and limited bioavailability. One of the solutions may be to develop a hydrogel as a potential hormone carrier, for epidermal and transdermal application. 
  • 3.3K
  • 01 Sep 2022
Topic Review
Classification of Lattice Structure
A lattice structure is made by a unit cell that is repeated in the space, making a larger functional structure; thus, it is a peculiar kind of cellular structure. The basic idea of cellular structures evolved from natural organic structures such as bamboo, bone, cork, etc. According to the literature, in many applications, lattice structures have been found to be superior to their other cellular counterparts, such as foam and honeycomb structures.
  • 3.3K
  • 12 Oct 2023
Topic Review
The Hazards of Skin Glycation and Related Inhibitors
Skin saccharification, a non-enzymatic reaction between proteins, e.g., dermal collagen and naturally occurring reducing sugars, is one of the basic root causes of endogenous skin aging. During the reaction, a series of complicated glycation products produced at different reaction stages and pathways are usually collectively referred to as advanced glycation end products (AGEs). AGEs cause cellular dysfunction through the modification of intracellular molecules and accumulate in tissues with aging. AGEs are also associated with a variety of age-related diseases, such as diabetes, cardiovascular disease, renal failure (uremia), and Alzheimer’s disease. AGEs accumulate in the skin with age and are amplified through exogenous factors, e.g., ultraviolet radiation, resulting in wrinkles, loss of elasticity, dull yellowing, and other skin problems. 
  • 3.3K
  • 24 Nov 2022
Topic Review
Visible-Light Photoredox Catalysis for the Thiol-Ene/Yne Reactions
Visible-light photoredox catalysis has been established as a popular and powerful tool for organic transformations owing to its inherent characterization of environmental friendliness and sustainability in the past decades. The thiol-ene/yne reactions, the direct hydrothiolation of alkenes/alkynes with thiols, represents one of the most efficient and atom-economic approaches for the carbon-sulfur bonds construction. In traditional methodologies, harsh conditions such as stoichiometric reagents or a specialized UV photo-apparatus were necessary suffering from various disadvantages. In particular, visible-light photoredox catalysis has also been demonstrated to be a greener and milder protocol for the thiol-ene/yne reactions in recent years. Additionally, unprecedented advancements have been achieved in this area during the past decade.
  • 3.3K
  • 11 Feb 2022
Topic Review
Nutritional Composition of Flaxseeds
Flaxseed (Linum usitatissimum L.) has gained worldwide recognition as a health food because of its abundance in diverse nutrients and bioactive compounds such as oil, fatty acids, proteins, peptides, fiber, lignans, carbohydrates, mucilage, and micronutrients. These constituents attribute a multitude of beneficial properties to flaxseed that makes its use possible in various applications, such as nutraceuticals, food products, cosmetics, and biomaterials.
  • 3.3K
  • 25 Oct 2022
Topic Review
Društvo Sa Ograničenom Odgovornošću
Društvo sa ograničenom odgovornošću (Serbian Cyrillic: друштво са ограниченом одговорношћу; abbr. d.o.o., Serbian Cyrillic: д.о.о.) is a kind of legal corporate entity in and Serbia which literally means (but is not entirely equal to) "limited liability society". It is often confused with the American term limited liability company, with which it shares some characteristics, but it is more similar to a limited partnership.
  • 3.3K
  • 01 Nov 2022
Topic Review
Social Hacking
Social hacking describes the act of attempting to manipulate outcomes of social behaviour through orchestrated actions. The general function of social hacking is to gain access to restricted information or to a physical space without proper permission. Most often, social hacking attacks are achieved by impersonating an individual or group who is directly or indirectly known to the victims or by representing an individual or group in a position of authority. This is done through pre-meditated research and planning to gain victims’ confidence. Social hackers take great measures to present overtones of familiarity and trustworthiness to elicit confidential or personal information. Social hacking is most commonly associated as a component of “social engineering”. Although the practice involves exercising control over human behaviour rather than computers, the term "social hacking" is also used in reference to online behaviour and increasingly, social media activity. The technique can be used in multiple ways that affect public perception and conversely, increase public awareness of social hacking activity. However, while awareness helps reduce the volume of hacks being carried out, technology has allowed for attack tools to become more sophisticated.
  • 3.3K
  • 20 Oct 2022
Topic Review
Celestial Coordinate System
In astronomy, a celestial coordinate system (or celestial reference system) is a system for specifying positions of satellites, planets, stars, galaxies, and other celestial objects relative to physical reference points available to a situated observer (e.g. the true horizon and north cardinal direction to an observer situated on the Earth's surface). Coordinate systems can specify an object's position in three-dimensional space or plot merely its direction on a celestial sphere, if the object's distance is unknown or trivial. The coordinate systems are implemented in either spherical or rectangular coordinates. Spherical coordinates, projected on the celestial sphere, are analogous to the geographic coordinate system used on the surface of Earth. These differ in their choice of fundamental plane, which divides the celestial sphere into two equal hemispheres along a great circle. Rectangular coordinates, in appropriate units, are simply the Cartesian equivalent of the spherical coordinates, with the same fundamental (x, y) plane and primary (x-axis) direction. Each coordinate system is named after its choice of fundamental plane.
  • 3.3K
  • 02 Dec 2022
Topic Review
Water on Mars
To assess Mars’ potential for both harboring life and providing useable resources for future human exploration, it is of paramount importance to comprehend the water situation on the planet. Therefore, studies have been conducted to determine any evidence of past or present water existence on Mars. While the presence of abundant water on Mars very early in its history is widely accepted, on its modern form, only a fraction of this water can be found, as either ice or locked into the structure of Mars’ plentiful water-rich materials. Water on the planet is evaluated through various evidence such as rocks and minerals, Martian achondrites, low volume transient briny outflows (e.g., dune flows, reactivated gullies, slope streaks, etc.), diurnal shallow soil moisture (e.g., measurements by Curiosity and Phoenix Lander), geomorphic representation (possibly from lakes and river valleys), and groundwater, along with further evidence obtained by probe and rover discoveries. One of the most significant lines of evidence is for an ancient streambed in Gale Crater, implying ancient amounts of “vigorous” water on Mars. Long ago, hospitable conditions for microbial life existed on the surface of Mars, as it was likely periodically wet. However, its current dry surface makes it almost impossible as an appropriate environment for living organisms; therefore, scientists have recognized the planet’s subsurface environments as the best potential locations for exploring life on Mars. As a result, modern research has aimed towards discovering underground water, leading to the discovery of a large amount of underground ice in 2016 by NASA, and a subglacial lake in 2018 by Italian scientists. Nevertheless, the presence of life in Mars’ history is still an open question. In this unifying context, the current review summarizes results from a wide variety of studies and reports related to the history of water on Mars, as well as any related discussions on the possibility of living organisms' existence on the planet.
  • 3.3K
  • 06 Feb 2022
Topic Review
Giant Cheetah
The giant cheetah (Acinonyx pardinensis) is an extinct felid species that was closely related to the modern cheetah.
  • 3.3K
  • 14 Oct 2022
Topic Review
Noocenosis
A Noocenosis (alternative spelling noocenose, noocoenosis or noöcenosis) from Greek νόος (noos) — "mind, thought, perception, sense" and κοινός (cenosis) – "common, mutual, shared, joint", is an artificial biological community (biocenosis) built upon a degraded ecosystem. A noocenosis is the result of structural improvements by man and differs from the original, evolutionarily constructed biological community. The concept noocenosis was first used in Russia (spelling: «нооценоз») in the 1990s by the ecologist Victor Vasilievich Petrashov (Петрашов, Виктор Васильевич). Academic use of the term noocenosis is still predominately limited to Post Soviet countries, with a few exceptions. Closely related terms include "Noobiocenosis" and "Noobiogeocenosis". The term "noobiogeocenosis was introduced in the 1970s by the ecologist Stanislav Semenovich Shwarts (Щварц, Станислав Семёнович). The concept noocenosis belongs to the discipline Ecology and was established by the Russian professor and ecologist Victor Vasilievich Petrashov in his 1993 publication Введение в нооценологи (Introduction to Noocenology). Parallel to the ecological characterization based on Petrashov the term has been adopted in other disciplines, including Economics, Industrial Ecology, Agricultural Science, Philosophy and other Humanity studies.
  • 3.3K
  • 25 Oct 2022
Topic Review
Basic Principles of Atomic Force Microscopy
Visualization of biomedical samples in their native environments at the microscopic scale is crucial for studying fundamental principles and discovering biomedical systems with complex interaction. The study of dynamic biological processes requires a microscope system with multiple modalities, high spatial/temporal resolution, large imaging ranges, versatile imaging environments and ideally in-situ manipulation capabilities. Development of new Atomic Force Microscopy (AFM) capabilities has made it such a powerful tool for biological and biomedical research. 
  • 3.3K
  • 15 Dec 2022
Topic Review
Silicon Field Effect Transistors (FET)
Highly sensitive and selective gas and volatile organic compound (VOC) sensor platforms with fast response and recovery kinetics are in high demand for environmental health monitoring, industry, and medical diagnostics. Among the various categories of gas sensors studied to date, field effect transistors (FETs) have proved to be an extremely efficient platform due to their miniaturized form factor, high sensitivity, and ultra-low power consumption. Despite the advent of various kinds of new materials, silicon (Si) still enjoys the advantages of excellent and reproducible electronic properties and compatibility with complementary metal–oxide–semiconductor (CMOS) technologies for integrated multiplexing and signal processing.
  • 3.3K
  • 26 Oct 2021
Topic Review
Externalizing Disorders
Externalizing disorders (or externalising disorders) are mental disorders characterized by externalizing behaviors, maladaptive behaviors directed toward an individual's environment, which cause impairment or interference in life functioning. In contrast to individuals with internalizing disorders who internalize (keep inside) their maladaptive emotions and cognitions, such feelings and thoughts are externalized (manifested outside) in behavior in individuals with externalizing disorders. Externalizing disorders are often specifically referred to as disruptive behavior disorders (attention-deficit/hyperactivity disorder, oppositional defiant disorder, and conduct disorder) or conduct problems which occur in childhood. Externalizing disorders, however, are also manifested in adulthood. For example, alcohol- and substance-related disorders and antisocial personality disorder are adult externalizing disorders. Externalizing psychopathology is associated with antisocial behavior, which is different from and often confused for asociality.
  • 3.3K
  • 25 Oct 2022
Topic Review
Azeotropes for Waste Recovery
Aiming for more sustainable chemical production requires an urgent shift towards synthetic approaches designed for waste minimization. In this context the use of azeotropes can be an effective tool for “recycling” and minimizing the large volumes of solvents, especially in aqueous mixtures, used. This review discusses the implementation of different kinds of azeotropic mixtures in relation to the environmental and economic benefits linked to their recovery and re-use. Examples of the use of azeotropes playing a role in the process performance and in the purification steps maximizing yields while minimizing waste. 
  • 3.3K
  • 11 Aug 2021
Topic Review
A Bioinformatics Workflow of Metabolomics Analysis
Metabolomics is an emerging field that quantifies numerous metabolites systematically. The key purpose of metabolomics is to identify the metabolites corresponding to each biological phenotype, and then provide an analysis of the mechanisms involved. Although metabolomics is important to understand the involved biological phenomena, the approach’s ability to obtain an exhaustive description of the processes is limited. Thus, an analysis-integrated metabolomics, transcriptomics, proteomics, and other omics approach is recommended. Such integration of different omics data requires specialized statistical and bioinformatics software. 
  • 3.3K
  • 25 May 2022
Topic Review
Electric Motor and Battery Faults of Electric Vehicles
Fault detection and diagnosis (FDD) is of utmost importance in ensuring the safety and reliability of electric vehicles (EVs). The EV’s power train and energy storage, namely the electric motor drive and battery system, are critical components that are susceptible to different types of faults. Failure to detect and address these faults in a timely manner can lead to EV malfunctions and potentially catastrophic accidents. In the realm of EV applications, Permanent Magnet Synchronous Motors (PMSMs) and lithium-ion battery packs have garnered significant attention.
  • 3.3K
  • 21 Jul 2023
Topic Review
Labor Exploitation
The exploitation of labor is a concept that pertains to the unfair or unjust treatment of workers by employers or those in positions of power within economic systems. It is often associated with the extraction of surplus value from labor, where workers are not adequately compensated for the value they contribute to the production process. This concept is central to Marxist economic theory and has broader implications in discussions about workers' rights and social justice.
  • 3.3K
  • 25 Jan 2024
Topic Review
Smart Education System
The requirement to develop a smart education system is critical in the era of ubiquitous technology. In the smart education environment, intelligent pedagogies are constructed to take advantage of technological devices and foster learners’ competencies which undoubtedly assist learners in dealing with knowledge and handling issues in a dynamic society more effectively and productively. 
  • 3.3K
  • 07 Feb 2024
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