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Topic Review
Visible-Light-Promoted Carbonylation Reactions
The abundant and inexpensive carbon monoxide (CO) is widely exploited as a C1 source for the synthesis of both fine and bulk chemicals. In this context, photochemical carbonylation reactions have emerged as a powerful tool for the sustainable synthesis of carbonyl-containing compounds (esters, amides, ketones, etc.).
  • 3.9K
  • 11 Aug 2021
Topic Review
Assessment of Gastrointestinal Autonomic Dysfunction
The autonomic nervous system delicately regulates the function of several target organs, including the gastrointestinal tract. Thus, nerve lesions or other nerve pathologies may cause autonomic dysfunction (AD). Some of the most common causes of AD are diabetes mellitus and α-synucleinopathies such as Parkinson’s disease. Widespread dysmotility throughout the gastrointestinal tract is a common finding in AD, but no commercially available method exists for direct verification of enteric dysfunction. Thus, assessing segmental enteric physiological function is recommended to aid diagnostics and guide treatment.
  • 3.9K
  • 24 Apr 2021
Topic Review
Water Cooler
A water cooler or water dispenser is a device that cools and dispenses water. Water coolers come in a variety of form factors, ranging from wall-mounted to bottle filler water cooler combination units, to bi-level units and other formats. They are generally broken up in two categories: point-of use (POU) water coolers and bottled water coolers. POU Water coolers are connected to a water supply, while bottled water coolers require delivery (or self-pick-up) of water in large bottles from vendors. Bottled water coolers can be top-mounted or bottom-loaded, depending on the design of the model. Bottled water coolers typically use 5 or 10-gallon dispensers commonly found on top of the unit. Pressure coolers are a subcategory of water coolers encompassing water fountains and direct-piping water dispensers. Water cooler may also refer to a primitive device for keeping water cool. Water coolers are a common metonym referring to workplace socialization.
  • 3.9K
  • 18 Oct 2022
Topic Review Peer Reviewed
SEM-PLS Approach to Green Building
Green buildings refer to buildings that decrease adverse environmental effects and maintain natural resources. They can diminish energy consumption, greenhouse gas emissions, the usage of non-renewable materials, water consumption, and waste generation while improving occupants’ health and well-being. As such, several rating tools and benchmarks have been developed worldwide to assess green building performance (GBP), including the Building Research Establishment Environmental Assessment Method (BREEAM) in the United Kingdom, German Sustainable Building Council (DGNB), Leadership in Energy and Environmental Design (LEED) in the United States and Canada, Comprehensive Assessment System for Built Environment Efficiency (CASBEE) in Japan, Green Star in Australia, Green Mark in Singapore, and Green Building Index in Malaysia. Energy management (EM) during building operation could also improve GBP. One of the best approaches to evaluating the impact of EM on GBP is by using structural equation modelling (SEM). SEM is a commanding statistical method to model testing. One of the most used SEM variance-based approaches is partial least squares (PLS), which can be implemented in the SmartPLS application. PLS-SEM uses path coefficients to determine the strength and significance of the hypothesised relationships between the latent constructs. 
  • 3.9K
  • 13 Apr 2022
Topic Review
Aerogel-Based Plasters
Aerogel has entered the construction field in the last two decades as a component of many insulation products, due to its high thermal performance. Aerogel-based plasters allow the matching of high thermal performance and limited thickness. This makes them suitable when retrofitting an existing building and also when restoring a heritage building. This entry presents the state of the art of the research on aerogel-based plasters as a part of the aerogel-products for the building sector.
  • 3.9K
  • 08 Dec 2020
Topic Review
Stereolithography
Being the earliest form of Additive manufacturing, Stereolithography (SLA) fabricates 3D objects by selectively solidifying the liquid resin through photopolymerization reaction. The ability to fabricate objects with high accuracy as well as a wide variety of materials brings much attention to stereolithography. Since its invention in 1980s, SLA underwent four generations of major technological innovation over the past 40 years. These innovations have thus result in a diversifies range of stereolithography systems with dramatically improved resolution, throughput, and materials selection for creating complex 3D objects and devices. In this paper, we review the four generations stereolithography processes, which are scanning, projection, continuous and volumetric stereolithography. For each generation, representative stereolithography system configurations are also discussed in detail. In addition, other derivative technologies, such as scanning-projection, multi-material, and magnetically assisted stereolithography processes, are also included in this review.
  • 3.9K
  • 16 Sep 2020
Topic Review
Tire Pyrolysis Oil
Energy is essential for the nature of life and the development of countries. The main demand for the 21st century is to fulfill growing energy needs. Pakistan, through the use of fossil fuels, meets energy demands. There is pressure on the economy of the country due to the massive reliance on fossil fuels, and this tendency is influenced by various environmental impacts. To overcome the burden on fossil fuels, more attention has been drawn to provide fossil fuel substitution. Tire pyrolysis is among the effective substitutes of the fuel technology that generates useful products of liquid oil, char, and pyro gas.
  • 3.9K
  • 30 Sep 2021
Topic Review
Fused 1,5-naphthyridines
Heterocyclic nitrogen compounds, including fused 1,5-naphthyridines, have versatile applications in synthetic organic chemistry and play an important role in the field of medicinal chemistry, as many of them have a wide range of biological activities. In this review, a wide range of synthetic protocols for the construction of this scaffold are presented. For example, Friedländer, Skraup, Semmlere-Wolff, and hetero-Diels-Alder, among others, are well known classical synthetic protocols used for the construction of the main 1,5-naphthyridine scaffold. These syntheses are classified according to the nature of the cycle fused to the 1,5-naphthyridine ring: carbocycles, nitrogen heterocycles, oxygen heterocycles, and sulphur heterocycles. In addition, taking into account the aforementioned versatility of these heterocycles, their reactivity is presented as well as their use as a ligand for metal complexes formation. Finally, those fused 1,5-naphthyridines that present biological activity and optical applications, among others, are indicated.
  • 3.9K
  • 31 Aug 2020
Topic Review
Diagnosis and Management of Onychophagia
Onychophagia is defined as chronic biting of the nail plate, nail folds, nail bed, and/or cuticle.
  • 3.9K
  • 25 Mar 2022
Topic Review
Bodhisattva Precepts
The Bodhisattva Precepts (traditional Chinese: 菩薩戒; ; pinyin: Púsà Jiè, Japanese: bosatsukai) are a set of moral codes used in Mahayana Buddhism to advance a practitioner along the path to becoming a Bodhisattva. Traditionally, monastics observed the basic moral code in Buddhism, the Prātimokṣa (such as that of the Dharmaguptaka), but in the Mahayana tradition, monks may observe the Bodhisattva Precepts as well.
  • 3.9K
  • 16 Nov 2022
Topic Review
Potato Proteins
About 35-45 % of all soluble potato proteins are fractions of albumin and globulin characterised by high molecular weight in the range of 40-45 kDa and high nutritive value, comparable to proteins of animal origin. They are soluble in water and in water and salt solutions, respectively; these are patatin glycoproteins, with a pIs in the range of 4.8–5.2. The second large group of potato proteins comprise fractions of protease inhibitors with a molecular weight in the range of 7–21 kDa, mostly acid soluble; they are often heat-resistant, showing a wide spectrum of healthpromoting effects, such as antimicrobial or antitumor, as well as antioxidant and antiradical. Properties of potato proteins depend strictly on the method of isolation and the applied factors, such as pH, ionic strength and temperature.
  • 3.9K
  • 26 Apr 2021
Topic Review
Entity–Component–System
Entity–component–system (ECS) is an architectural pattern that is mostly used in game development. ECS follows the composition over inheritance principle that allows greater flexibility in defining entities where every object in a game's scene is an entity (e.g. enemies, bullets, vehicles, etc.). Every Entity consists of one or more components which add behavior or functionality. Therefore, the behavior of an entity can be changed at runtime by adding or removing components. This eliminates the ambiguity problems of deep and wide inheritance hierarchies that are difficult to understand, maintain and extend. Common ECS approaches are highly compatible and often combined with data-oriented design techniques.
  • 3.9K
  • 23 Nov 2022
Topic Review
GeForce 900 Series
The GeForce 900 series is a family of graphics processing units developed by Nvidia, succeeding the GeForce 700 series and serving as the high-end introduction to the Maxwell microarchitecture, named after James Clerk Maxwell. They are produced with TSMC's 28 nm process. With Maxwell, the successor to Kepler, Nvidia expected three major outcomes: improved graphics capabilities, simplified programming, and better energy efficiency compared to the GeForce 700 series and GeForce 600 series. Maxwell was announced in September 2010, with the first Maxwell-based GeForce consumer-class products released in early 2014.
  • 3.9K
  • 17 Nov 2022
Topic Review
Alginate-Based Biomaterials
Alginates are naturally occurring polysaccharides extracted from brown marine algae and bacteria. Being biocompatible, biodegradable, non-toxic and easy to gel, alginates can be processed into various forms, such as hydrogels, microspheres, fibers and sponges, and have been widely applied in biomedical field.
  • 3.9K
  • 31 May 2021
Topic Review
3′UTR Length Dynamics: Releasing mRNAs from Stability Control
The 3′Untranslated regions (3′UTRs) of mRNAs, are non-coding regulatory platforms that control stability, fate and the correct spatiotemporal translation of mRNAs. Although initially considered as stabilizing features of the ORF, further work identified a number of new 3’UTR functions that controlled where, when and how mRNAs were translated. Furthermore, recent research has enriched the view of 3’UTRs from static regulators of mRNA translation to highly dynamic and modular regulatory platforms that respond to different stimuli by changing their structure. By using alternative polyadenylation and cleavage sites, alternative exons or by including exonized Alu cassettes, 3’UTRs modify their length, change their sequence and consequently their inventory of associated regulatory sites to establish different co-regulatory events.
  • 3.9K
  • 13 Sep 2022
Topic Review
Various Protein Kinase Inhibitors as Anticancer Agents
Protein kinases (PTKs) are enzymes that regulate the biological activity of proteins by phosphorylation of certain amino acid residues. This reaction causes a conformational change from an inactive to an active form of the protein, which is one of the most important regulatory mechanisms of the cell cycle and transduction of external signals. Dysregulation of protein kinases activity is implicated in the processes of carcinogenesis and the progression of various solid cancers. Therefore, protein kinases are prime targets for the development of selective anticancer drugs.
  • 3.9K
  • 22 Apr 2022
Topic Review
Design and Operation Mode of Zigzag Air Classifier
The zigzag (ZZ) classifier is a sorting and classification device with a wide range of applications (e.g. recycling, food industry). Due to the possible variation of geometry and process settings, the apparatus is used for various windows of operation due to the specifications of the separation (e.g. cut sizes from 100 µm to several decimetres, compact and fluffy materials as well as foils).
  • 3.9K
  • 27 Apr 2022
Topic Review
Society 5.0
Big Data, the Internet of Things, and robotic and augmented realities are just some of the technologies that belong to Industry 4.0. These technologies improve working conditions and increase productivity and the quality of industry production. However, they can also improve life and society as a whole. A new perspective is oriented towards social well-being and it is called Society 5.0. Industry 4.0 supports the transition to the new society, but other drivers are also needed. 
  • 3.9K
  • 17 Nov 2021
Topic Review
Wild Vigna Legumes
Legumes (family Fabaceae) represent the third largest family among flowering plants, consisting of approximately 650 genera and 20, 000 species which possess an undeniable vital nutritional value for both humans and animals due to their protein content. The genus Vigna is a huge and important set of legumes consisting of more than 200 species. The term under-exploited wild Vigna species has been attributed to some Vigna species of legumes that have not yet been domesticated. They do not possess commercial names since they have not got a common popular use by people or groups of people. Very few domesticated legumes species exist with more than one hundred (100) wild species under-exploited despite global food demand. A recent study explored farmers’ perceptions, preferences, and possible utilization of some wild Vigna species of legumes through quantitative and qualitative surveys conducted in a mid and high altitude agro-ecological zones in Tanzania to obtain the opinion of 150 farmers about wild legumes and their uses.
  • 3.9K
  • 30 Oct 2020
Topic Review
Here
Here Technologies (trading as HERE) is a company that provides mapping and location data and related services to individuals and companies. It is majority-owned by a consortium of German automotive companies (namely Audi, BMW, and Daimler), whilst other companies also own minority stakes. Its roots date back to U.S.-based Navteq in 1985, which was acquired by Finland-based Nokia in 2007. Here is currently based in Amsterdam. Here captures location content such as road networks, buildings, parks and traffic patterns. It then sells or licenses that mapping content, along with map related navigation and location services to other businesses such as Alpine, Garmin, BMW, Oracle and Amazon.com. In addition, Here provides platform services to smartphones. It provides location services through its own Here applications, and also for GIS and government clients and other providers, such as Bing, Facebook and Yahoo! Maps. Here has maps of nearly 200 countries, offers voice guided navigation in 94 countries, provides live traffic information in 33 countries and has indoor maps available for about 49,000 unique buildings in 45 countries. The company is also working on self-driving technology. HERE Technologies India Private Limited is recognized among India's Best Companies to Work For 2019 ranking at place #33 and among India's Best Workplaces for Women 2019 (Top 25) from "Great Place to Work". HERE is once again the highest-ranked location platform vendor in the index. HERE has cemented its leadership position thanks to the continuous improvements it has made to its core Open Location Platform, doubling down on its efforts for developers, and a string of new initiatives including a renewed focus on data privacy.
  • 3.9K
  • 19 Oct 2022
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