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Topic Review
Pathophysiology-Based Traumatic Brain Injury
Traumatic brain injury (TBI) is a leading cause of disability and death among children and young adults, with an incidence of approximately 1.7 million per year in the USA, resulting in 52,000 deaths. Survivors of the initial impact must still contend with the consequences of trauma, as not all injury occurs at the time of impact. The primary injury results from forces applied to the head and involve direct structural damage to the brain. This triggers a cascade of events leading to neurological damage that evolves secondary injury. Several external brain insults, both intracranial and systemic, may complicate and worsen the secondary injury.
  • 5.2K
  • 07 Mar 2024
Topic Review
Distributed Generation Integration into Grid
According to [25], DGs could also be defined as a small source of power production for storage (usually within the range of less than a kW and tens of MW), which is not a portion of the huge, centralized power network and is located close to the load. Another school of thought defines DGs as power pockets usually located near consumers, which have a relatively small capacity of 30 MW or less, with the ability to economically support the distribution grid. This description involves DG technologies such as photovoltaic systems, concentrating solar power, micro turbines, reciprocating engines and fuel cells.
  • 5.2K
  • 16 Sep 2021
Topic Review
Peumo (Cryptocarya alba), a Native Fruit of Chile
The peumo (Cryptocarya alba) is a native fruit from central Chile that belongs to the Lauraceae family. To characterize the development and the potential health benefits of this edible fruit, quality and physiological parameters, along with antioxidant capacity, were evaluated during three clearly defined developmental stages of the fruit in two seasons. 
  • 5.2K
  • 10 Jan 2022
Topic Review
Chaotic Image Encryption
Chaos is the characteristic of a system whose current state is guaranteed to be highly sensitive to the previous state (spatial chaos), the initial conditions (temporal chaos), or both (spatio-temporal chaos). Such a sensitivity makes the output or the behavior of a chaotic system difficult to predict. Chaos theory justifies and formulates the apparent disorder of chaotic systems on the basis of orderly patterns, structured feedback loops, iterative repetitions, self-organization, self-similarity, fractals, etc. Chaotic maps, attractors, and sequences all refer to the mathematical structures used for this formulation. Chaotic systems, maps, attractors, and sequences have been of great interest to the research community. They have been used for security purposes in a broad variety of applications ranging from smart grids to communication systems. Especially, chaotic encryption has been used for encrypting a variety of content types in addition to images.
  • 5.2K
  • 27 Jul 2022
Topic Review
Global Warming
Global warming is the ongoing rise of the average temperature of the Earth's climate system. It is a major aspect of climate change which, in addition to rising global surface temperatures, also includes its effects, such as changes in precipitation. While there have been prehistoric periods of global warming, observed changes since the mid-20th century have been unprecedented in rate and scale. The Intergovernmental Panel on Climate Change (IPCC) concluded that "human influence on climate has been the dominant cause of observed warming since the mid-20th century". These findings have been recognized by the national science academies of major nations and are not disputed by any scientific body of national or international standing. The largest human influence has been the emission of greenhouse gases, with over 90% of the impact from carbon dioxide and methane. Fossil fuel burning is the principal source of these gases, with agricultural emissions and deforestation also playing significant roles. Climate sensitivity to these gases is affected by feedbacks, such as loss of snow cover, increased water vapour, and melting permafrost. Land surfaces are heating faster than the ocean surface, leading to heat waves, wildfires, and the expansion of deserts. Increasing atmospheric energy and rates of evaporation are causing more intense storms and weather extremes, damaging infrastructure and agriculture. Surface temperature increases are greatest in the Arctic and have contributed to the retreat of glaciers, permafrost, and sea ice. Environmental impacts include the extinction or relocation of many species as their ecosystems change, most immediately in coral reefs, mountains, and the Arctic. Surface temperatures would stabilize and decline a little if emissions were cut off, but other impacts will continue for centuries, including rising sea levels from melting ice sheets, rising ocean temperatures, and ocean acidification from elevated levels of carbon dioxide. Mitigation efforts to address global warming include the development and deployment of low carbon energy technologies, policies to reduce fossil fuel emissions, reforestation, forest preservation, as well as the development of potential climate engineering technologies. Societies and governments are also working to adapt to current and future global warming impacts, including improved coastline protection, better disaster management, and the development of more resistant crops. Countries work together on climate change under the umbrella of the United Nations Framework Convention on Climate Change (UNFCCC), which has near-universal membership. The goal of the convention is to "prevent dangerous anthropogenic interference with the climate system". The IPCC has stressed the need to keep global warming below 1.5 °C (2.7 °F) compared to pre-industrial levels in order to avoid some irreversible impacts. With current policies and pledges, global warming by the end of the century is expected to reach about 2.8 °C (5.0 °F). At the current greenhouse gas (GHG) emission rate, the carbon budget for staying below 1.5 °C (2.7 °F) would be exhausted by 2028.
  • 5.2K
  • 12 Oct 2022
Topic Review
Timeline of Cholera
This is a timeline of cholera, a disease caused by the bacterium Vibrio cholerae.
  • 5.2K
  • 30 Nov 2022
Topic Review
Mesoporous Carbon
Mesoporous carbon is a promising material having multiple applications. It can act as a catalytic support and can be used in energy storage devices. Moreover, mesoporous carbon controls body’s oral drug delivery system and adsorb poisonous metal from water and various other molecules from an aqueous solution. The accuracy and improved activity of the carbon materials depend on some parameters. The recent breakthrough in the synthesis of mesoporous carbon, with high surface area, large pore-volume, and good thermostability, improves its activity manifold in performing functions. Considering the promising application of mesoporous carbon, it should be broadly illustrated in the literature. 
  • 5.2K
  • 07 May 2021
Topic Review Peer Reviewed
Main Carotenoids Produced by Microorganisms
Carotenoids are the pigments present in plants, animals, and microorganisms which are responsible for a broad variety of colors found in nature. Their capacity as antioxidants mainly established their marketable success as health, food, and feed supplements, and cosmetics components. Currently, chemical synthesis dominates the worldwide market; however, due to the high biological value of natural carotenoids, the production scheme is moving towards microbial production as a profitable alternative. 
  • 5.2K
  • 13 Apr 2022
Topic Review
Action Myoclonus–Renal Failure Syndrome
Action myoclonus–renal failure (AMRF) syndrome causes episodes of involuntary muscle jerking or twitching (myoclonus) and, often, kidney (renal) disease. Although the condition name refers to kidney disease, not everyone with the condition has problems with kidney function.
  • 5.2K
  • 23 Dec 2020
Topic Review
Adipose tissue in the breast
       Breast is a dynamic organ mainly composed of adipose and fibroglandular tissues. The adipose tissue extends from the collarbone to the underarm and around the center of the ribcage. Adipose tissue as an endocrine organ constantly affects the dynamics of the breast. However, the role of adipose tissue in breast has been mostly studied in terms of obesity and cancer.  In this review, we have discussed the role of breast adipose tissue in breast development from embryonic stage to mature breast. Further, we draw attention to the involvement of breast adipose tissue in pregnancy, lactation and involution associated breast changes. Finally, we depict how breast adipose tissue can affect breast cancer. 
  • 5.2K
  • 26 Aug 2020
Topic Review
Anemia in Kawasaki disease
Kawasaki disease (KD) is an acute childhood vasculitis syndrome that affects the walls of both small- and medium-sized blood vessels (vasculitis), especially coronary arteries. Anemia is a common clinical feature in KD patients and is thought to have a more prolonged duration of active inflammation. In this review, we will discuss the anemia in KD, possibility of hemolysis, the necessity of iron supplementation and importance of anemia in the pathogenesis of KD.
  • 5.2K
  • 05 Nov 2020
Topic Review
Synergism (Theology)
In Christian theology, synergism is the position of those who hold that salvation involves some form of cooperation between divine grace and human freedom. It stands opposed to monergism, a doctrine most commonly associated with the Lutheran and Reformed Protestant traditions, whose soteriologies have been strongly influenced by the North African bishop and Latin Church Father Augustine of Hippo (354–430). Lutheranism, however, confesses a monergist salvation and synergist damnation (see below). Synergism is upheld by the Orthodox and Roman Catholic Churches, and by the Methodist and Pentecostal traditions of Protestantism. It is an integral part of Arminian theology. Synergism and semipelagianism each teach some collaboration in salvation between God and man, but semipelagian thought teaches that the beginning half of faith is an act of human will. The Council of Orange (529), Lutheran Formula of Concord (1577), and other local councils each condemned semipelagianism as heresy.
  • 5.2K
  • 24 Nov 2022
Topic Review
Preconsolidation Pressure
Preconsolidation pressure is the maximum effective vertical overburden stress that a particular soil sample has sustained in the past. This quantity is important in geotechnical engineering, particularly for finding the expected settlement of foundations and embankments. Alternative names for the preconsolidation pressure are preconsolidation stress, pre-compression stress, pre-compaction stress, and preload stress. A soil is called overconsolidated if the current effective stress acting on the soil is less than the historical maximum. The preconsolidation pressure can help determine the largest overburden pressure that can be exerted on a soil without irrecoverable volume change. This type of volume change is important for understanding shrinkage behavior, crack and structure formation and resistance to shearing stresses. Previous stresses and other changes in a soil's history are preserved within the soil's structure. If a soil is loaded beyond this point the soil is unable to sustain the increased load and the structure will break down. This breakdown can cause a number of different things depending on the type of soil and its geologic history. Preconsolidation pressure cannot be measured directly, but can be estimated using a number of different strategies. Samples taken from the field are subjected to a variety of tests, like the constant rate of strain test (CRS) or the incremental loading test (IL). These tests can be costly due to expensive equipment and the long period of time they require. Each sample must be undisturbed and can only undergo one test with satisfactory results. It is important to execute these tests precisely to ensure an accurate resulting plot. There are various methods for determining the preconsolidation pressure from lab data. The data is usually arranged on a semilog plot of the effective stress (frequently represented as σ'vc) versus the void ratio. This graph is commonly called the e log p curve or the consolidation curve.
  • 5.2K
  • 17 Oct 2022
Topic Review
Social Environment and Environmental Attitudes
Social environment may the formation of citizens' attitudes toward the natural environment, namely, the environmental attitudes.
  • 5.2K
  • 15 Nov 2021
Biography
Sabine Hossenfelder
Sabine Hossenfelder (born 18 September 1976) is a German author and theoretical physicist who researches quantum gravity. She is a Research Fellow at the Frankfurt Institute for Advanced Studies where she leads the Superfluid Dark Matter group. She is the author of Lost in Math: How Beauty Leads Physics Astray, which explores the concept of elegance in fundamental physics and cosmology. Hosse
  • 5.2K
  • 15 Nov 2022
Topic Review
Panopticon
The Panopticon is a type of institutional building and a system of control designed by the English philosopher and social theorist Jeremy Bentham in the late 18th century. The scheme of the design is to allow all (pan-) inmates of an institution to be observed (-opticon) by a single watchman without the inmates being able to tell whether or not they are being watched. Although it is physically impossible for the single watchman to observe all the inmates' cells at once, the fact that the inmates cannot know when they are being watched means that they are motivated to act as though they are being watched at all times. Thus, they are effectively compelled to regulate their own behaviour. The name may also allude to the many-eyed giant Panoptes in Greek mythology, some of whose eyes were always awake, making him a highly effective watchman. The design consists of a circular structure with an "inspection house" at its centre, from which the manager or staff of the institution is able to watch the inmates. The inmates, who are stationed around the perimeter of the structure, are unable to see into the inspection house. Bentham conceived the basic plan as being equally applicable to hospitals, schools, sanatoriums, and asylums, but he devoted most of his efforts to developing a design for a Panopticon prison. It is his prison that is now most widely meant by the term "panopticon". Bentham described the Panopticon as "a new mode of obtaining power of mind over mind, in a quantity hitherto without example". Elsewhere, in a letter, he described the Panopticon prison as "a mill for grinding rogues honest".
  • 5.2K
  • 24 Nov 2022
Topic Review
Forgetting
Forgetting or disremembering is the apparent loss or modification of information already encoded and stored in an individual's short or long-term memory. It is a spontaneous or gradual process in which old memories are unable to be recalled from memory storage. Problems with remembering, learning and retaining new information are a few of the most common complaints of older adults. Studies show that retention improves with increased rehearsal. This improvement occurs because rehearsal helps to transfer information into long-term memory. Forgetting curves (amount remembered as a function of time since an event was first experienced) have been extensively analyzed. The most recent evidence suggests that a power function provides the closest mathematical fit to the forgetting function.
  • 5.2K
  • 09 Oct 2022
Topic Review
Removal of Purines from Beer
Beer corresponds to a fermented alcoholic beverage composed of several components, including purine compounds. These molecules, when ingested by humans, can be catabolized into uric acid, contributing to uric acid’s level increase in serum, which may lead to hyperuricemia and gout. To assure a proper management of this disease, physicians recommend restrictive dietary measures, particularly by avoiding the consumption of beer. Therefore, it is of relevance to develop efficient methods to remove purine compounds from alcoholic beverages such as beer. There are several enzymatic, biological, and adsorption methods reported envisaging purine compounds’ removal. Some enzymatic and biological methods present drawbacks, which can be overcome by adsorption methods. Within adsorption methods, adsorbent materials, such as activated carbon or charcoal, have been reported and applied to beer or wort samples, showing an excellent capacity for adsorbing and removing purine compounds. By ensuring the selective removal of purine compounds from this beverage, beer can be taken by hyperuricemic and gouty patients, avoiding restrictive dietary measures, while decreasing the related healthcare economic burden. 
  • 5.2K
  • 23 Nov 2021
Topic Review
DENGUE and ZIKA Flaviviruses Nucleic Acid Vaccine
Dengue virus and Zika virus are mosquito-borne, single-stranded, positive-sense RNA viruses that belong to the Flaviviridae family. Both the viruses are closely related and have similarities with other flaviviruses. Dengue virus (DENV) causes a severe febrile illness with fever, joint pain, and rash leading to a life-threatening condition in severe cases. While Zika virus (ZIKV) primarily causes mild fever, it can be passed from a pregnant mother to her fetus, resulting in severe birth defect microcephaly and even causing a rare autoimmune disease—Guillain–Barre syndrome. 
  • 5.2K
  • 08 Jun 2022
Topic Review
Paraprobiotics
Paraprobiotics are defined as “inactivated microbial cells (non-viable) that confer a health benefit to the consumer” and hold the ability to regulate the adaptive and innate immune systems, to exhibit anti-inflammatory, antiproliferative and antioxidant properties, and to exert antagonistic effect against pathogens, thus confirming that viability of probiotics is not an absolute pre-requisite for promoting health effects. 
  • 5.2K
  • 05 May 2021
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