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Topic Review
Artificial Intelligence in Hypertension Management
Arterial hypertension (AH) is a progressive issue that grows in importance with the increased average age of the world population. The potential role of artificial intelligence (AI) in its prevention and treatment is firmly recognized. Indeed, AI application allows personalized medicine and tailored treatment for each patient.
  • 1.3K
  • 17 Feb 2023
Topic Review
RadioIodine Treatment
Thyroid radioiodide or radioiodine therapy (RAI) is one of the oldest known and used targeted therapies. In thyroid cancer, it has been used for more than eight decades and is still being used to improve thyroid tumor treatment to eliminate remnants after thyroid surgery, and tumor metastases. Knowledge at the molecular level of the genes/proteins involved in the process has led to improvements in therapy, both from the point of view of when, how much, and how to use the therapy according to tumor type. The effectiveness of this therapy has spread into other types of targeted therapies, and this has made sodium/iodide symporter (NIS) one of the favorite theragnostic tools. 
  • 1.3K
  • 29 Mar 2021
Topic Review
Polysaccharide-Based Active Coatings
Polysaccharide-based active coatings supplemented with plant extracts such as cashew leaves, pomegranate peel, red roselle, apple fiber, and green tea extracts rich in phenolic compounds and their derivatives have been reported to be excellent substituents to replace chemically formulated wax coatings.
  • 1.3K
  • 19 Apr 2022
Topic Review
Autosomal Recessive Spastic Ataxia of Charlevoix-Saguenay (ARSACS)
Autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS) is an early-onset neurodegenerative disease that was originally discovered in the population from the Charlevoix-Saguenay-Lac-Saint-Jean (CSLSJ) region in Quebec.
  • 1.3K
  • 25 Jan 2022
Topic Review
Genesis of Endotheliopathy
Endotheliopathy, according to the “two-activation theory of the endothelium”, is triggered by the activated complement system in critical illnesses, such as sepsis, diabetes and polytrauma, leading to two distinctly different molecular dysfunctions: (1) the activation of the inflammatory pathway due to the release of inflammatory cytokines, such as interleukins, interferons and tumor necrosis factors, and (2) the activation of the microthrombotic pathway due to the exocytosis of hemostatic factors, including ultra-large von Willebrand factor (ULVWF) multimers and FVIII. These lead to inflammation and microthrombogenesis. The former produces inflammatory diseases, and the latter produces endotheliopathy-associated vascular microthrombotic disease (EA-VMTD), which orchestrates not only TTP-like syndrome characterized by the triad of consumptive thrombocytopenia, microangiopathic hemolytic anemia and multiorgan dysfunction syndrome, but also many other endotheliopathic syndromes. The diagnostic features of EA-VMTD are well established now and therapeutic strategies are being formulated. 
  • 1.3K
  • 11 Oct 2022
Topic Review
Sustainable Technologies for Older Adults
Technology offers smart, sustainable solutions to enable older adults to live in better conditions. These solutions must cover not only healthcare, but also social and emotional needs in people’s daily lives. Smart homes and cities, the IoT, ICT, robotic systems, artificial intelligence and other technologies can offer efficient, scalable, cost-effective and sustainable solutions. These solutions are not only accurate once cognitive or physical decline has become apparent but are also of great interest for the prevention and early detection of age-related decline.
  • 1.3K
  • 28 Sep 2021
Topic Review
New COVID-19 Vaccinations
Vaccination can be, in fact, an efficient way to mitigate the devastating effect of the pandemic and offer protection to some vulnerable strata of the population (i.e., the elderly) and reduce the social and economic burden of the current crisis.
  • 1.3K
  • 25 Mar 2021
Topic Review
Pathogenetic Mechanisms of Hypertension–Brain-Induced Complications
Hypertension is well known to alter the structure and function of cerebral blood vessels not only through its haemodynamics effects but also for its relationships with endothelial dysfunction, oxidative stress and inflammation.
  • 1.3K
  • 09 Mar 2022
Topic Review
Medical Services for Insomnia in Korea
Researchers reviewed the National Patient Sample data from the Health Insurance Review and Assessment Service to determine healthcare utilization in patients diagnosed with insomnia (International Classification of Diseases-10 codes G470, F510) between January 2010 and December 2016.
  • 1.3K
  • 04 Jan 2022
Topic Review
Factors Influencing Usage Behavior on Mobile Health Applications
As people pay more attention to health, mobile health applications (mHealth apps) are becoming popular. These apps offer health services that run on mobile devices to help improve users’ health behaviors. However, few studies explore what motivates users to continue to use these apps. 
  • 1.3K
  • 10 Feb 2022
Topic Review
NK Cells—the Immune System against Glioblastoma
Glioblastoma (GBM) is the primary cancer with the highest incidence within the central nervous system. Natural killer (NK) cells are innate lymphocytes that play an important role in immunosurveillance, acting alongside other immune cells in the response against various types of malignant tumors and the prevention of metastasis. NK cells are being exploited in many ways to treat cancer. The broad arsenal of NK-based therapies includes adoptive transfer of in vitro expanded and activated cells, genetically engineered cells to contain chimeric antigen receptors (CAR-NKs), in vivo stimulation of NK cells (by cytokine therapy, checkpoint blockade therapies, etc.), and tumor-specific antibody-guided NK cells, among others. 
  • 1.3K
  • 28 Feb 2022
Topic Review
Calculus as a Risk Factor for Periodontal Disease
Based on the 2018 classification of periodontal disease, a series of articles have been published describing the decision points of periodontal therapy and how the findings collected at those decision points can be used as guidelines for periodontal therapy.
  • 1.3K
  • 11 Nov 2022
Topic Review
Guinea Worm Disease
Dracunculiasis, also known as Guinea worm disease (GWD), is a neglected tropical disease (NTD) caused by a parasite (Dracunculus medinensis). In the past, dracunculiasis was known as “the disease of the empty granary” because of the difficulties patients had in going to work in fields or to school when affected by this disease. In tropical areas, the condition has been widespread in economically disadvantaged communities, and has been associated with reduced economic status and low levels of education. By development and optimization of multi-layered control measures, transmission by the vector has been interrupted, but there are foci in several African countries with a high risk of compromising the results obtained in the control of this neglected disease. 
  • 1.3K
  • 25 Nov 2022
Topic Review
A Multifactorial Approach for Sarcopenia Assessment
Sarcopenia refers to a progressive and generalized weakness of skeletal muscle as individuals age. Sarcopenia usually occurs after the age of 60 years and is associated with a persistent decline in muscle strength, function, and quality. A comparison of the risk factors associated with sarcopenia based on the European Working Group on Sarcopenia (1 and 2) in Older People, the Asian Working Group for Sarcopenia (1 and 2), the International Working Group on Sarcopenia, and the Foundation for the National Institutes of Health revealed no consistent patterns. Accordingly, the identification of a single risk factor for sarcopenia is unpredictable due to its “multifactorial” pathogenesis, with the involvement of a multitude of factors.
  • 1.3K
  • 29 Dec 2021
Topic Review
Flexible Wearable Sensors in Medical Monitoring
Wearable devices for health monitoring are usually made into miniaturized rigid circuit boards and block power supplies placed on various parts of the human body, especially the wrist, to monitor body data in real-time.
  • 1.3K
  • 01 Dec 2022
Topic Review
Demand Creation for COVID-19 Vaccination
As more approved COVID-19 vaccines are made available and supply meets or exceeds demand, medical and public health professionals will increasingly be faced with the challenge of vaccine hesitancy. This article describes a demand creation strategy to overcome COVID-19 vaccine hesitancy using methods and evidence from behavioral science and social marketing, and describes a specific campaign aimed at increasing vaccination rates in high supply settings.
  • 1.3K
  • 13 Apr 2021
Topic Review
Masks
Face masks can protect humans through their filtration function. They include different types and mechanisms of filtration whose performance depends on the texture of the fabric, the latter of which is strongly related to the manufacturing method. 
  • 1.3K
  • 24 Jan 2022
Topic Review
Hybrid Nanobioengineered Nanomaterial-Based Electrochemical Biosensors
Nanobioengineered-based hybrid electrochemical biosensors exploit the synergistic properties of hybrid systems that connect biomolecules with nanomaterials to engineer highly sensitive biosensing platforms for the specific electrochemical detection of different target analytes.
  • 1.3K
  • 30 Jun 2022
Topic Review
Wearable Sensing Technology and Long COVID
Long COVID consequences have changed the perception towards disease management, and it is moving towards personal healthcare monitoring. Wearable sensors are being explored for its simplicity, portability, and real time health monitoring system. These smart devices can detect physiological changes in the human body providing a real time solution for quicker medical decision.
  • 1.3K
  • 09 Jan 2023
Topic Review
Fall Prevention for Pediatric Inpatients
Falls account for a high proportion of the safety accidents experienced by hospitalized children. This entry aims to analyze the contents and effects of fall prevention programs for pediatric inpatients to develop more adaptable fall prevention programs.
  • 1.3K
  • 09 Jun 2021
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