Your browser does not fully support modern features. Please upgrade for a smoother experience.
Subject:
All Disciplines Arts & Humanities Biology & Life Sciences Business & Economics Chemistry & Materials Science Computer Science & Mathematics Engineering Environmental & Earth Sciences Medicine & Pharmacology Physical Sciences Public Health & Healthcare Social Sciences
Sort by:
Most Viewed Latest Alphabetical (A-Z) Alphabetical (Z-A)
Filter:
All Topic Review Biography Peer Reviewed Entry Video Entry
Topic Review Peer Reviewed
Reactive Transport Processes in Proton Exchange Membrane Fuel Cells
Proton exchange membrane fuel cells are devices that directly convert chemical energy to electricity. A hydrogen oxidation reaction takes place on the anode side, generating protons and electrons. In the cathode, oxygen reduction reaction involving oxygen, proton and electron occurs, producing water and heat. The water content in PEMFCs should be maintained at a reasonable amount to avoid water flooding or membrane dehydration. The thermal management and water management of PEMFCs are important for an efficient and stable operation of PEMFCs. Inside the multiscale spaces of PEMFCs, multiphase flow with a phase change, heat and mass transfer, proton and electron conduction, and electrochemical reaction simultaneously take place, which play important roles in the performance, lifetime and cost of PEMFCs. These processes should be well understood for better designing PEMFCs and improving the thermal management and water management.
  • 1.3K
  • 13 May 2025
Topic Review
Immune Checkpoints Inhibitors in the Treatment of Melanoma
Metastatic melanoma is a highly immunogenic tumor with very poor survival rates due to immune system escape-mechanisms. Immune checkpoint inhibitors (ICIs) targeting the cytotoxic T-lymphocyte-associated protein 4 (CTLA4) and the programmed death-1 (PD1) receptors, are being used to impede immune evasion. 
  • 1.3K
  • 04 Nov 2022
Topic Review Video Peer Reviewed
Strategic Intelligence: A Semantic Leadership Perspective
This paper explores the notion of strategic intelligence, namely with respect to leadership and business-oriented areas. Strategic intelligence is a researched concept that primarily concerns the collection and analysis of intelligence for policy and military planning, mainly at national and international levels, whereas this study of management and organizational decision-making application is an extension of that. This article’s subject is the necessity for strategic intelligence, a crucial competence for leaders, managers, and companies striving to remain competitive, to be utilized and best leveraged in today’s volatile and dynamic business contexts. This study follows a research design that includes a thorough literature review and bibliometric research, executed via VoSViewer, illustrating the concept of strategic intelligence from a leadership point of view as a driver of competitive advantage, enhanced by knowledge dynamics. Furthermore, this article points out that the limitations are acknowledged because the literature on the matter is limited, as strategic intelligence is relatively new to the business sector; moreover, more research is required to fully understand and use the potential of strategic intelligence in business growth. Overcoming these limitations and continuing to study the strategic intelligence concept could, on the one hand, use multiple platforms, such as scholarly articles or encyclopedias, and, on the other hand, support businesses in gaining a competitive edge and making informed decisions that can fuel their success in an ever-evolving market.
  • 1.3K
  • 02 Jul 2024
Topic Review
Fructose and the Liver
Fructose possesses an open-chain chemical conformation and is therefore much more reactive than glucose. Experimental studies have shown that a high fructose intake promotes oxidative stress, inflammation, higher serum uric acid levels, hypertriglyceridemia, higher systolic blood pressure, and insulin resistance(). In humans, the physiological impact depends on the formulation in which the fructose is consumed; consumption via solids and liquids differently affects microbiota composition, gut integrity, and liver toxicity.
  • 1.3K
  • 12 Oct 2021
Topic Review
Apiaceae as Antioxidants
The excess level of reactive oxygen species (ROS) disturbs the oxidative balance leading to oxidative stress, which, in turn, causes diabetes mellites, cancer, and cardiovascular diseases. Dietary antioxidants can balance these effects of ROS and oxidative stress. In recent years, there has been an increasing trend in the use of herbal products for personal and beauty care. The Apiaceae (previously Umbelliferae) family is a good source of antioxidants, predominantly phenolic compounds, therefore, widely used in the pharmaceutical, cosmetic, cosmeceutical, flavor, and perfumery industries. These natural antioxidants include polyphenolic acids, flavonoids, carotenoids, tocopherols, and ascorbic acids, and exhibit a wide range of biological effects, including anti-inflammatory, anti-aging, anti-atherosclerosis, and anticancer.
  • 1.3K
  • 17 Dec 2021
Topic Review
Dictyostelium discoideum
Dictyostelium discoideum has provided a useful, simple model to aid in unraveling the complex pathological characteristics of neurological disorders including Alzheimer’s disease, Parkinson’s disease, Huntington’s disease, neuronal ceroid lipofuscinoses and lissencephaly. 
  • 1.3K
  • 06 May 2022
Topic Review
MAb114
mAb114 is a monoclonal antibody that is being evaluated as a treatment for Ebola virus disease. Its discovery was led by the laboratory of Nancy Sullivan at the United States National Institute of Health Vaccine Research Center and J. J. Muyembe-Tamfum from the Institut National pour la Recherche Biomedicale (INRB) in the Democratic Republic of Congo, working in collaboration with the Institute of Biomedical Research and the United States Army Medical Research Institute of Infectious Diseases. mAb114 was isolated from the blood of a survivor of the 1995 outbreak of Ebola virus disease in Kikwit, Democratic Republic of Congo roughly ten years later. In early 2018, a Phase 1 clinical trial of mAb114 was conducted by Martin Gaudinski within the Vaccine Research Center Clinical Trials Program that is led by Julie E. Ledgerwood. mAb114 is also being evaluated during the 2018 North Kivu Ebola outbreak. mAb114 has also shown success with lowering the mortality rate from ~70% to about 34%. In August 2019, Congolese health authorities, the World Health Organization, and the U.S. National Institutes of Health promoted the use of mAb114, alongside REGN-EB3, a similar Regeneron-produced monoclonal antibody treatment, over other treatments yielding higher mortality rates, after ending clinical trials during the outbreak.
  • 1.3K
  • 30 Nov 2022
Topic Review
Perovskite Solar Cells with ZnO Electron Transport Layer
Perovskite solar cells (PSCs) have experienced rapid development in the past period of time, and a record efficiency of up to 25.7% has been yielded. The PSCs with the planar structure are the most prevailing, which not only can significantly simplify the device fabrication process but also reduce the processing temperature. Particularly, the electron transport layer (ETL) plays a critical role in boosting the device performance of planar PSCs. ZnO is a promising candidate as the ETL owing to its high transparency, suitable energy band structure, and high electron mobility. Moreover, ZnO is easy to be processed at a low cost and low energy. 
  • 1.3K
  • 05 Jan 2023
Topic Review
Autonomous Landing Site Detection
The advancement of autonomous technology in Unmanned Aerial Vehicles (UAVs) has piloted a new era in aviation. While UAVs were initially utilized only for the military, rescue, and disaster response, they are now being utilized for domestic and civilian purposes as well. In order to deal with its expanded applications and to increase autonomy, the ability for UAVs to perform autonomous landing will be a crucial component.
  • 1.3K
  • 09 Aug 2023
Topic Review
Wood Waste Management from the Furniture Industry
Proper management of wood waste (WW) from the furniture industry has become an important issue. Life-cycle assessment (LCA) is a tool that is widely used for identifying environmental gains in WW management strategies.
  • 1.3K
  • 04 Jan 2024
Topic Review
Polysaccharide-Based Edible Films Incorporated with Essential Oil Nanoemulsions
Edible films with essential oils (EOs) are becoming increasingly popular as an alternative to synthetic packaging due to their environmentally friendly properties and ability as carriers of active compounds. However, the required amounts of EOs to impart effective antimicrobial properties generally exceed the organoleptic acceptance levels. However, by nanoemulsifying EOs, it is possible to increase their antimicrobial activity while reducing the amount required. By incorporating EOs nanoemulsions into the packaging matrix, these edible films can help to extend the shelf-life of food products while also improving the quality and safety of the food product during storage. It can be concluded that these edible films have the potential to be used in the food industry as a green, sustainable, and biodegradable method for perishable foods preservation.
  • 1.3K
  • 06 Apr 2022
Topic Review
Endoscopy Lifetime Systems Architecture
Systems engineering captures the desires and needs of the customer to conceptualize a system from the overall goal down to the small details prior to any physical development. While many systems projects tend to be large and complicated (i.e., cloud-based infrastructure, long-term space travel shuttles, missile defense systems), systems engineering can also be applied to smaller, complex systems. The system of interest is the endoscope, a standard biomedical screening device used in laparoscopic surgery, screening of upper and lower gastrointestinal tracts, and inspection of the upper airway.
  • 1.3K
  • 25 Oct 2022
Topic Review
Premature Ventricular Complexes
Premature ventricular complexes (PVCs) are frequently encountered in clinical practice. The association of PVCs with adverse cardiovascular outcomes is well established in the context of structural heart disease, yet not so much in the absence of structural heart disease.
  • 1.3K
  • 08 Oct 2023
Topic Review
Metal Tolerance Protein
Metal tolerance proteins (MTPs) are plant divalent cation transporters that play important roles in plant metal tolerance and homeostasis. Poplar is an ideal candidate for the phytoremediation of heavy metals because of its numerous beneficial attributes. Here, 22 MTP genes in P. trichocarpa were identified and classified into three major clusters and seven groups according to phylogenetic relationships. An evolutionary analysis suggested that PtrMTP genes had undergone gene expansion through tandem or segmental duplication events. Moreover, all PtrMTPs were predicted to localize in the vacuole and/or cell membrane, and contained typical structural features of the MTP family, cation efflux domain. The temporal and spatial expression pattern analysis results indicated the involvement of PtrMTP genes in poplar developmental control. Under heavy metal stress, most of PtrMTP genes were induced by at least two metal ions in roots, stems or leaves. In addition, PtrMTP8.1, PtrMTP9 and PtrMTP10.4 displayed the ability of Mn transport in yeast cells, and PtrMTP6 could transport Co, Fe and Mn. These findings will provide an important foundation to elucidate the biological functions of PtrMTP genes, and especially their role in regulating heavy metal tolerance in poplar.
  • 1.3K
  • 26 Oct 2020
Topic Review
Forest Fire Protection
The entry presents some significant issues related to the fire protection infrastructure in forests. In every forest complex a sufficiently dense network of fire roads is an extremely important element of the fire protection system. The requirements to identify roads as fire roads within the forest communication network and to maintain their condition up to a certain technical standard has been briefly explained.
  • 1.3K
  • 09 Nov 2020
Topic Review
Sustainable Energy Development
The global COVID-19 pandemic has had strong impacts on national and international freight, construction and tourism industry, supply chains, and has resulted in a rapid decline in the demand for traditional energy sources. In fact, research has outlined that urban areas depend on global supply chains for their day-to-day basic functions, including energy supplies, food and safe access to potable water. The disruption of global supply chains can leave many urban areas in a very vulnerable position, in which their citizens may struggle to obtain their basic supplies, as the COVID-19 crisis has recently shown. Therefore, solutions aiming to enhance local food, water and energy production systems, even in urban environments, have to be pursued. The COVID-19 crisis has also highlighted in the scientific community the problem of people’s exposure to outdoor and indoor pollution, confirmed as a key element for the increase both in the transmission and severity of the contagion, on top of involving health risks on their own. In this context, most nations are going to adopt new preferential policies to stimulate the development of relevant sustainable energy industries, based on the electrification of the systems supplied by renewable energy sources as confirmed by the International Energy Agency (IEA). Thus, while there is ongoing research focusing on a COVID 19 vaccine, there is also a need for researchers to work cooperatively on novel strategies for world economic recovery incorporating renewable energy policy, technology and management. In this framework, the Sustainable Development of Energy, Water and Environment Systems (SDEWES) conference provides a good platform for researchers and other experts to exchange their academic thoughts, promoting the development and improvements on the renewable energy technologies as well as their role in systems and in the transition towards sustainable energy systems. The 14th SDEWES Conference was held in Dubrovnik, Croatia. It brought together around 570 researchers from 55 countries in the field of sustainable development. The present Special Issue of Energies,
  • 1.3K
  • 02 Nov 2020
Topic Review
Thoracic Outlet Syndrome
Thoracic Outlet Syndrome is a collection of symptoms in the shoulder and upper extremity area that results in pain, numbness, and tingling. Identification of thoracic outlet syndrome is complex and a thorough clinical examination in addition to appropriate clinical testing can result in diagnosis. Practitioners must consider the pathology of thoracic outlet syndrome in their differential diagnosis for shoulder and upper extremity pain symptoms so that patients are directed appropriately to timely interventions. Patients with a definitive etiology who have failed conservative management are ideal candidates for surgical correction. This manuscript will discuss thoracic outlet syndrome, occurrence, physical presentation, clinical implications, and diagnosis and management.
  • 1.3K
  • 21 Apr 2021
Topic Review
Biomedical Compositions Containing Hydroxyapatite
Regenerative medicine is becoming a rapidly evolving technique in today’s biomedical progress scenario. Scientists around the world suggest the use of naturally synthesized biomaterials to repair and heal damaged cells. Hydroxyapatite (HAp) has the potential to replace drugs in biomedical engineering and regenerative drugs. HAp is easily biodegradable, biocompatible, and correlated with macromolecules, which facilitates their incorporation into inorganic materials. 
  • 1.3K
  • 08 May 2021
Topic Review
Neuroprotective Herbs for Alzheimer’s Disease
Alzheimer’s disease (AD) is a multifactorial, progressive, neurodegenerative disease that is characterized by memory loss, personality changes, and a decline in cognitive function. Medicinal plants and herbal remedies are now gaining more interest as complementary and alternative interventions and are a valuable source for developing drug candidates for AD. Indeed, several scientific studies have described the use of various medicinal plants and their principal phytochemicals for the treatment of AD. 
  • 1.3K
  • 11 Oct 2021
Topic Review
Human Cytomegalovirus (HCMV)
Human cytomegalovirus (HCMV) is a β-herpesvirus, also known as human herpes virus 5. Compared with other human herpesviruses, the prevalence of HCMV is high, and more than 90% of the general population is an HCMV carrier. HCMV infection can disrupt homeostasis by affecting the host cell autophagy, apoptosis, proliferation, invasion, angiogenesis, and immune response [5]. Increasing evidence indicates that HCMV causes the occurrence and progression of inflammation [6], atherosclerosis, Crohn’s disease, and various cancers. More seriously, HCMV can trigger life-threatening diseases in immunosuppressed individuals. Thus, it is necessary to elucidate the pathogenic mechanism of HCMV and discover novel targets and strategies for anti-HCMV treatment. Apoptosis is a form of programmed cell death, which is essential for maintaining normal physiology and tissue function by cleaning up cells that are damaged, dysfunctional, or no longer necessary. The survival and accumulation of damaged or unnecessary cells contribute to numerous diseases, such as cancers, in addition to immunological, neurodegenerative, cardiovascular, and infectious diseases. Apoptosis generally occurs through two distinct pathways: intrinsic and extrinsic. Interestingly, both extrinsic and intrinsic apoptotic pathways can be activated by pathogenic infection.
  • 1.3K
  • 13 Jul 2021
  • Page
  • of
  • 2728
Featured Entry Collections
>>

Featured Reprints

>>
Encyclopedia of Digital Society, Industry 5.0 and Smart City
Encyclopedia of Engineering
Encyclopedia of Social Sciences
Encyclopedia of Medieval Royal Iconography
Academic Video Service
Feedback