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Encyclopedia Entry Collections collate entries on a specific topic to build a community of authors and readers to record and popularize knowledge, and develop new ideas and research directions. These are led by Academic Editors who are experts in their field, and will published on a dedicated page on the Encyclopedia platform.
Gastrointestinal Disease
Number of Entries: 71
Gastrointestinal disease is a very common and frequently occurring disease, with a wide range of types and a total incidence of about 20% of the population. The cause of gastrointestinal disease is the imbalance between the protective mechanism and the injury mechanism of the human body. While traditional medicine kills harmful bacteria in the stomach, it also kills the beneficial bacteria necessary for the stomach. Although the symptoms are alleviated and inflammation is eliminated, t ...More
Hypertension and Cardiovascular Diseases
Number of Entries: 62
Hypertension is a major public health concern worldwide because of its rising prevalence and concomitant risks of cardiovascular diseases. Coping strategies may encompass a full spectrum of clinical, epidemiological, experimental, and technological factors to inspire front-line practices and shape critical thinking. This entry collection aims to assemble entries of wealthy topics related to clinical, therapeutic, and population sciences of hypertension and cardiovascular diseases that ...More
Immunotherapy in Solid Tumors
Number of Entries: 42
Immunotherapy has emerged as a major therapeutic modality in oncology. The number of immunotherapy drug approvals has been increasing, with numerous treatments in clinical and preclinical development. These therapeutics help the host immune system recognize cancer as foreign, promote the immune system, and relieve the inhibition that allows growth and spread of tumors.   Despite advancements in the treatment of hematological malignancies, solid tumors still represent a challenge ...More
Myocardial Infarction
Number of Entries: 1
Cardiovascular diseases are the leading cause of death worldwide, and acute myocardial infarction is still responsible for a significant number of preventable deaths. In recent months, the COVID-19 pandemic has led to a significant decrease in the number of patients with acute coronary syndromes who have managed to arrive in time to cath labs for the guideline-recommended revascularization procedure. Inflammation plays a pivotal role in the pathophysiology of acute myocardial infarctio ...More
Number of Entries: 34
Neurodegeneration refers to the progressive loss of neuron structure or function, which may eventually lead to cell death. Many neurodegenerative diseases, such as amyotrophic lateral sclerosis, multiple sclerosis, Parkinson's disease, Alzheimer's disease, Huntington's disease and prion disease, are the results of neurodegenerative processes. Neurodegeneration can be found in many different levels of neuronal circuits in the brain, from molecules to systems. Since there is no known met ...More
Academic Editor: Vittorio Gentile
Number of Entries: 0
Neuroinflammation seems to play a pivotal role in various chronic neurodegenerative diseases, characterized also by the pathogenetic accumulation of specific protein aggregates. Several of these proteins have been shown to be substrates of transglutaminases, calcium-dependent enzymes that catalyze protein crosslinking reactions. Recently, it has been demonstrated that transglutaminase 2 (TG2), a member of the transglutaminase enzymes family, may also be involved in molecular mechanisms ...More