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Topic Review
Anticancer Effects of α-Linolenic Acid
α-linolenic acid (ALA) belongs to the family of n-3 polyunsaturated fatty acids (n-3 PUFAs) and contains a carbon–carbon double bond on the third carbon atom at the methyl end of the carbon chain. This family of essential fatty acids also includes eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). ALA has gradually attracted increased attention due to its nutritional and medicinal advantages. Studies have shown that ALA exerts beneficial effects on a variety of diseases, including cancer.
  • 102
  • 19 Mar 2024
Topic Review
Types and General Role of Organic Amendments
Salinity and metal stress are significant abiotic factors that negatively influence plant growth and development. These factors lead to diminished agricultural yields on a global scale. Organic amendments have emerged as a potential solution for mitigating the adverse effects of salinity and metal stress on plants. When plants experience these stresses, they produce reactive oxygen species, which can impair protein synthesis and damage cellular membranes. Organic amendments, including biochar, vermicompost, green manure, and farmyard manure, have been shown to facilitate soil nitrogen uptake, an essential component for protein synthesis, and enhance various plant processes such as metabolism, protein accumulation, and antioxidant activities. Researchers have observed that the application of organic amendments improves plant stress tolerance, plant growth, and yield.
  • 311
  • 19 Mar 2024
Topic Review
Peptide for Bone and Cartilage Regeneration
The healing of osteochondral defects (OCDs) that result from injury, osteochondritis, or osteoarthritis and bear lesions in the cartilage and bone, pain, and loss of joint function in middle- and old-age individuals presents challenges to clinical practitioners because of non-regenerative cartilage and the limitations of current therapies. Bioactive peptide-based osteochondral (OC) tissue regeneration is becoming more popular because it does not have the immunogenicity, misfolding, or denaturation problems associated with original proteins. 
  • 457
  • 19 Mar 2024
Topic Review Peer Reviewed
Developing Emotional Intelligence
Daniel Goleman perceptively and accurately noted that emotional intelligence is critical to leadership success, claiming that emotional intelligence is far more important to leadership emergence and effectiveness than intellectual capacity. Goleman’s research later confirmed an 85% relationship between emotional intelligence and leader effectiveness. It may be the most critical area for current and aspiring leaders to develop. While leadership scholars accept the importance of emotional intelligence for leadership and the fact that emotional intelligence can be developed, there appears to be some uncertainty around how emotional intelligence can be developed. The authors shed light on that area and provide current and aspiring leaders with some proven strategies for developing the four predominant components of emotional intelligence. The importance of emotional intelligence to leadership is well documented, and leaders would be well served by working to heighten their levels of emotional intelligence and, in doing so, increase their leadership potential, efficacy, and impact.
  • 547
  • 19 Mar 2024
Topic Review
Non-Iterative Cluster Routing
In conventional routing, a capsule network employs routing algorithms for bidirectional information flow between layers through iterative processes.
  • 482
  • 19 Mar 2024
Topic Review
Mechanisms Linking Hyperuricemia and Kidney Disease Progression
Gout is highly prevalent in patients with chronic kidney disease (CKD) and end-stage renal disease (ESRD), owing to impaired uric acid excretion. However, treating gout in this population is challenging due to concerns about medication safety and efficacy with reduced kidney function. The 2020 American College of Rheumatology (ACR) guidelines recommend nonsteroidal anti-inflammatory drugs (NSAIDs), colchicine, and systemic glucocorticoids to treat acute gout flares. These can also be used as prophylaxis when starting urate-lowering therapy (ULT) to prevent flares. For ULT drugs like allopurinol, febuxostat, probenecid, benzbromarone, lesinurad, and pegloticase, key efficacy outcomes per most guidelines include: achieving target serum urate levels (<6 or <5 mg/dL), resolving tophi, reducing gout flares over time, improving quality of life, and radiographic changes. 
  • 153
  • 19 Mar 2024
Topic Review
Mobile Live Commerce on Purchase Intention
Mobile live commerce is emerging as a new distribution channel as connectivity and information sharing become easier due to the increase in the use of SNS and mobile phones.
  • 157
  • 19 Mar 2024
Topic Review
Radiological Aspects of Sacroiliitis
Sacroiliitis is the inflammation of the sacroiliac joint, the largest axial joint in the human body, contributing to 25% of lower back pain cases. It can be detected using various imaging techniques like radiography, Magnetic Resonance Imaging (MRI), and Computed Tomography (CT) scans. Treatments range from conservative methods to invasive procedures. Recent advancements in artificial intelligence offer precise detection of this condition through imaging. Treatment options range from physical therapy and medications to invasive methods like joint injections and surgery. 
  • 107
  • 19 Mar 2024
Topic Review
SARS-CoV-2 ORF3a Protein as Therapeutic Target against COVID-19
The ORF3a (open reading frame 3a) protein found in SARS-CoV-2, represents a promising target for antiviral treatment due to its multifaceted role in viral pathogenesis, cytokine storms, disease severity, and mortality. ORF3a contributes significantly to viral pathogenesis by facilitating viral assembly and release, essential processes in the viral life cycle, while also suppressing the body’s antiviral responses, thus aiding viral replication. ORF3a also has been implicated in triggering excessive inflammation, characterized by NF-κB-mediated cytokine production, ultimately leading to apoptotic cell death and tissue damage in the lungs, kidneys, and the central nervous system. 
  • 172
  • 19 Mar 2024
Topic Review
Snail Shell Waste in Food Industries
Effective waste management has become an urgent societal challenge. Food waste is made up of items meant for human consumption that are lost, polluted, disposed of, or deteriorated; the reutilization of shells from mollusk waste is a severe problem in terms of environmental protection and the development of the circular economy. The properties of waste shells are presented and discussed, including their biological–natural origin and high calcium carbonate content. This could add social and innovation focus on shell waste management, getting a non-toxic, eco-sustainable, low-cost, biodegradable supplement to invest in. Furthermore, it has the potential to support the circular economy approach by creating a closed system that minimizes the use of natural resources and environmental contamination. 
  • 280
  • 19 Mar 2024
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