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Topic Review
Biography
Topic Review
Drop-in Biofuels
Drop-in biofuels have a plant based origin and can be blended gradually into the existing fuel mix. The usage of drop-in biofuels ensures that little to no adjustments are required relative to existing fuel infrastructure. Non drop-in biofuels include alcohols such as (m)ethanol and gaseous fuels which cannot be used in a diesel engine without adjustments. In this study, the potential of drop-in biofuels is addressed. Based on their suitability as a marine fuel and their drop-in character, five drop-in biofuels are selected. These fuels include Fatty Acid Methyl Esters (FAME), Hydrotreated Vegetable Oil (HVO), Fast-Pyrolysis with full hydrodeoxygenation (FP), Hydrothermal Liquefaction with full hydrodeoxygenation (HTL) and Gasification with consequent Fischer–Tropsch synthesis (GFT).
2.5K
16 Sep 2021
Topic Review
Drowning Behaviour and Signs
Drowning poses a significant threat, resulting in unexpected injuries and fatalities. To promote water sports activities, it is crucial to develop surveillance systems that enhance safety around pools and waterways.
227
18 Jan 2024
Topic Review
Drug Delivery System Fabricated by Microfluidics
Traditional drug therapy faces challenges such as drug distribution throughout the body, rapid degradation and excretion, and extensive adverse reactions. In contrast, micro/nanoparticles can controllably deliver drugs to target sites to improve drug efficacy. Unlike traditional large-scale synthetic systems, microfluidics allows manipulation of fluids at the microscale and shows great potential in drug delivery and precision medicine. Well-designed microfluidic devices have been used to fabricate multifunctional drug carriers using stimuli-responsive materials.
689
08 Nov 2022
Topic Review
Drug Resistance Mechanisms in Tuberculosis
The increased incidence of multidrug-resistant (MDR) Mycobacterium tuberculosis (Mtb) strains, defined as resistant to at least isoniazid and rifampin, the two highly bactericidal first-line drugs, is a major concern for tuberculosis (TB) control. The worldwide estimate of almost half a million incident cases of MDR/rifampin-resistant TB, is causing increasing concern. In this view, it is important to continuously update the knowledge on the mechanisms involved in the development of drug-resistant TB. Clinical, biological and microbiological reasons account for the generation of resistance, including: (i) nonadherence of patients to their therapy, and/or errors of physicians in therapy management, (ii) complexity and poor vascularization of granulomatous lesions, which obstruct drug distribution to some sites, resulting in resistance development, (iii) intrinsic drug resistance of tubercle bacilli, (iv) formation of non-replicating, drug-tolerant bacilli inside the granulomas, (v) development of mutations in Mtb genes, which are the most important molecular mechanisms of resistance. Here, a piece of information on the interplay of these factors is provided, to facilitate the clinical and microbiological management of drug-resistant TB at the global level, with attention also to the most recent diagnostic methods.
1.3K
21 Apr 2020
Topic Review
Drying Biomass Using Solar Energy
In the world, energy used for drying processes consumes 7–15% of industrial energy. Therefore, the cost of this energy is a crucial challenge to looking for an alternative source of energy, for example, solar energy. Solar energy is available in almost all the world, is free and provides a clean and free pollution energy source. Furthermore, solar energy has a higher development potential than other alternative energy sources, such as the ocean, biomass and geothermal.
825
28 Dec 2022
Topic Review
DSResSol
Protein solubility is an important thermodynamic parameter that is critical for the characterization of a protein’s function, and a key determinant for the production yield of a protein in both the research setting and within industrial (e.g., pharmaceutical) applications. Experimental approaches to predict protein solubility are costly, time-consuming, and frequently offer only low success rates. To reduce cost and expedite the development of therapeutic and industrially relevant proteins, a highly accurate computational tool for predicting protein solubility from protein sequence is sought. While a number of in silico prediction tools exist, they suffer from relatively low prediction accuracy, bias toward the soluble proteins, and limited applicability for various classes of proteins. In this study, researchers developed a novel deep learning sequence-based solubility predictor, DSResSol, that takes advantage of the integration of squeeze excitation residual networks with dilated convolutional neural networks and outperforms all existing protein solubility prediction models. This model captures the frequently occurring amino acid k-mers and their local and global interactions and highlights the importance of identifying long-range interaction information between amino acid k-mers to achieve improved accuracy, using only protein sequence as input. DSResSol outperforms all available sequence-based solubility predictors by at least 5% in terms of accuracy when evaluated by two different independent test sets. Compared to existing predictors, DSResSol not only reduces prediction bias for insoluble proteins but also predicts soluble proteins within the test sets with an accuracy that is at least 13% higher than existing models. Researchers derive the key amino acids, dipeptides, and tripeptides contributing to protein solubility, identifying glutamic acid and serine as critical amino acids for protein solubility prediction. Overall, DSResSol can be used for the fast, reliable, and inexpensive prediction of a protein’s solubility to guide experimental design.
539
14 Jan 2022
Topic Review
DTS (Sound System)
DTS, Inc. (originally Digital Theater Systems) is an American company that makes multichannel audio technologies for film and video. Based in Calabasas, California, the company introduced its DTS technology in 1993 as a competitor to Dolby Laboratories, incorporating DTS in the film Jurassic Park (1993). The DTS product is used in surround sound formats for both commercial/theatrical and consumer-grade applications. It was known as The Digital Experience until 1995. DTS licenses its technologies to consumer electronics manufacturers. The DTS brand was acquired by Tessera Holding Corporation in December 2016, then Tessera was renamed to Xperi Corporation.
1.8K
15 Nov 2022
Topic Review
Dual-Frequency Solid-State Lasers for Synthetic-Wave Absolute-Distance Interferometry
Frequency-difference-stabilized dual-frequency solid-state lasers with tunable and large frequency difference have become an ideal light source for the high-accuracy absolute-distance interferometric system due to their stable multistage synthetic wavelengths.
346
06 Apr 2023
Topic Review
Dual-Motor Coupling Drive System for Electric Vehicles
The driving range of electric vehicles (EVs) is still an important factor restricting their development. Although the rising battery energy density has reached a bottleneck, which is a key constraint, the drive energy management strategy also has a significant effect and can improve the driving range of EVs. Herein, the typical configurations of the dual-motor coupling drive system (DCDS) are introduced, and the power distribution strategies of the DCDS are comprehensively reviewed.
477
11 May 2023
Topic Review
DubaiSat-1
DubaiSat-1 is a remote sensing Earth observation satellite built by the Emirates Institution for Advanced Science and Technology (EIAST) under an agreement with Satrec Initiative, a satellite manufacturing company in South Korea . DubaiSat-1 was launched on 29 July 2009 into a 680 km altitude sun-synchronous polar orbit from the Baikonur launch site in Kazakhstan, along with several other satellites on board the Dnepr launch vehicle.
377
24 Nov 2022
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