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Topic Review
Cosmetic Properties of Plant Extract-Derived Carbon Dots
Plant extract-derived carbon dots (C-dots) have emerged as promising components for sustainability and natural inspiration to meet consumer demands. Plant extract-derived C-dots offer distinct advantages over conventional synthetic materials by taking advantage of the inherent properties of plants, such as antioxidant, anti-inflammatory, and UV protective properties. 
  • 309
  • 13 Oct 2023
Topic Review
Clinical Efficacy of 5-Fluorouracil and Bleomycin in Dermatology
Bleomycin and 5-fluorouracil (5-FU) are widely used in various dermatological disorders. Both drugs are well-recognized as antineoplastic drugs and exert their effect by blocking the cell cycle. Topical and intralesional formulations are available and have been studied in both non-neoplastic and cancerous lesions. However, data comparing the effect of bleomycin and 5-FU in the dermatological disorders are limited.
  • 308
  • 24 Jan 2024
Topic Review
Skin Aging, Metabolism, and Related Products
Skin aging affects the metabolism of three major substances, which are glucose, protein, and lipids, and the metabolism of the three major substances in the skin also affects the process of skin aging. Some drugs or compounds can regulate the metabolic disorders mentioned above to exert anti-aging effects. Currently, there are a variety of products, but most of them focus on improving skin collagen levels. Skin aging is closely related to metabolism, and they interact with each other. Regulating specific metabolic disorders in the skin is an important anti-aging strategy.
  • 296
  • 19 Jan 2024
Topic Review
Pigmented Purpuric Dermatoses
Pigmented purpuric dermatoses (PPD) encompass a group of chronic skin conditions characterized by the presence of petechiae, purpura, and pigmentation changes.
  • 294
  • 07 Mar 2024
Topic Review
Oxidative Stress and Skin Cancer
Oxidative stress is caused by an imbalance between the production and subsequent accumulation of reactive oxygen species (ROS) in cells and tissues and the capacity of a biological system to eliminate these reactive substances. Systemic oxidative stress biomarkers in plasma, serum, urine, or red blood cells have been found to be elevated in many diseases, including skin cancer. UV radiation (UVR) induces damage to biomolecules that enter the bloodstream, reinforcing systemic oxidative stress. On the other hand, pre-existing systemic oxidative stress does not supply the skin with the adequate micronutrients and antioxidant resources to ameliorate the skin’s antioxidant defense against UVR. In both scenarios, skin cancer patients are exposed to oxidative conditions. In the case of warts, oxidation is linked to chronic inflammation, while impaired cutaneous antioxidant defense could ineffectively deal with possible oxidative stimuli from viral agents, such as HPV. 
  • 291
  • 06 Dec 2023
Topic Review
Emerging Oral Treatments for Psoriasis
Psoriasis is a chronic inflammatory disease with a worldwide prevalence of 1–3% that can be associated with psoriatic arthritis and other comorbidities and causes a significant burden and impairment of health-related quality of life. Psoriasis is an immune-mediated inflammatory disease (IMID) with a pathogenic admixture of autoinflammatory and autoimmune components and involvement of both innate and adaptive immune systems.
  • 290
  • 17 Feb 2024
Topic Review
Collagen-Based Nanofibers for Skin Regeneration Applications
Skin regeneration after an injury is very vital, but this process can be impeded by several factors. Regenerative medicine is a developing biomedical field with the potential to decrease the need for an organ transplant. 
  • 289
  • 27 Jul 2023
Topic Review
Myeloproliferative Related Dermatosis with Indolent Clinical Outcomes
Myeloid neoplasms and acute leukemias include different entities that have been recently re-classified taking into account molecular and clinicopathological features. Two major articles were published in 2022, the ICC and the WHO classifications. The myelodysplastic syndrome/myeloproliferative neoplasm (MDS/MPN) category comprises a heterogeneous group of hybrid neoplastic myeloid diseases characterized by the co-occurrence of clinical and pathological features of both myelodysplastic and myeloproliferative neoplasms. The most frequent entity in this category is chronic myelomonocytic leukemia (CMML) which is, after acute myeloid leukemia (AML), the main myeloid disorder prone to develop cutaneous manifestations.
  • 285
  • 04 Jan 2024
Topic Review
Hormones of Hair Loss in Non-Scarring Alopecias
Hair loss is a common clinical condition connected with serious psychological distress and reduced quality of life. Hormones play an essential role in the regulation of the hair growth cycle.
  • 282
  • 08 Mar 2024
Topic Review
Immunity against Non-Melanoma Skin Cancer
Non-melanoma skin cancers (NMSCs), including basal cell carcinoma (BCC) and cutaneous squamous cell carcinoma (cSCC), are the most frequent types of cancers among Caucasians. Non-melanoma skin cancers (NMSCs) occur frequently in the Caucasian population and are considered a burden for health care. Risk factors include ultraviolet (UV) radiation, ethnicity and immunosuppression. This indicates the importance of immunosurveillance in preventing NMSC. However, the immunological mechanisms mediating immunosurveillance against NMSC are not fully known. 
  • 279
  • 31 Oct 2023
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