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Topic Review
Heat Therapy
Heat therapy, also called thermotherapy, is the use of heat in therapy, such as for pain relief and health. It can take the form of a hot cloth, hot water bottle, ultrasound, heating pad, hydrocollator packs, whirlpool baths, cordless FIR heat therapy wraps, and others. It can be beneficial to those with arthritis and stiff muscles and injuries to the deep tissue of the skin. Heat may be an effective self-care treatment for conditions like rheumatoid arthritis. Heat therapy is most commonly used for rehabilitation purposes. The therapeutic effects of heat include increasing the extensibility of collagen tissues; decreasing joint stiffness; reducing pain; relieving muscle spasms; reducing inflammation, edema, and aids in the post acute phase of healing; and increasing blood flow. The increased blood flow to the affected area provides proteins, nutrients, and oxygen for better healing.
  • 793
  • 31 Oct 2022
Topic Review
Small Leucine-Rich Proteoglycans in Retina
Small Leucine-Rich Proteoglycans (SLRPs) are key extracellular matrix proteins that play a role in many fundamental biological processes involved in the maintenance of retinal homeostasis. 
  • 793
  • 26 Jul 2021
Topic Review
History of Emerging Infectious Diseases
The discovery of disease-causing pathogens is an important activity in the field of medical science. Many viruses, bacteria, protozoa, fungi, helminthes and prions are identified as a confirmed or potential pathogen. In the United States, a Centers for Disease Control program, begun in 1995, identified over a hundred patients with life-threatening illnesses that were considered to be of an infectious cause, but that could not be linked to a known pathogen. The association of pathogens with disease can be a complex and controversial process, in some cases requiring decades or even centuries to achieve.
  • 793
  • 07 Nov 2022
Topic Review
COVID19 Immunity To Immunology
Immunity is an important term directly related to prevent any kind of infection spreading -particularly Covid19 under this pandemic situation . The specs of immunity depends on various factors like Foods & Diets , Environment / Ecology , Good Habits , Natural Remedies like Herbs & Anti-Oxidant therapy. Now we will discuss the every aspects of Immunity for boosting it up for a natural prevention of Covid19 ! . It is our sociological consiousnrss to maintain  strictly our immune system will be strong enough to fight against this Viral Curse .In the Pandemic world of Covid19 there are 300 types of vaccine-evelopment works are ongoing . In india also we have seen SII ( Pune ) are under trial of Phase2-3 trials . AstraZeneca - Oxford university , Cansino , Pfizer are trying under trial vaccine . As we are all aware that it is a long way to  nd out the ethical trial ( Clinical eciency ) universally U.S.S.R has been under claim stage . We the common people are in good hope that the vaccination will get in success to stop such Spike Crown .Without the term immunity vaccination will not be effecrive to irradicate the viral infection .
  • 793
  • 29 Oct 2020
Topic Review
The Gut-Immune-Brain Axis in Inflammatory Bowel Disease
Inflammatory bowel disease (IBD) is a chronic inflammatory disease comprising two major clinical entities—Crohn’s disease (CD) and ulcerative colitis (UC). IBD incidence remains constantly high in industrialized countries and continuously rises in emerging economies. Importantly, IBD is associated with neuropsychiatric symptoms that strongly worsen IBD disease burden. Mounting evidence indicates that chronic gut inflammation induces a systemic immune response that might cause the CNS manifestation in IBD. In line with this, biologicals targeting inflammatory circuits exerted robust positive effects on depressive symptoms in many autoimmune diseases, and in IBD in particular. Therefore, research in recent years increasingly focused on the characterization of local and systemic immune reactions in IBD, and on entry routes of inflammatory cells and molecules into the CNS. The ultimate aim is to understand how the changes in the neuroimmune landscape impair the function of neurons to cause neuropsychiatric symptoms. In addition, the role of intestinal microbiota in the gut–immune–brain axis in IBD will be discussed. 
  • 793
  • 18 Oct 2022
Topic Review
Mental Imagery
Mental imagery is a term used to describe the cognitive process of simulating sensations, actions, or other types of experiences through generating and using mental images, including metaphors.
  • 793
  • 18 Mar 2021
Topic Review
Medical Imaging Applications
The advancement of micro-electro-mechanical systems and small-sized optical components enable the fabrication of imaging devices with promising performance as compared to the traditional medical devices. Such devices enable the detection of lesions/tumors at an earlier stage and act as a guide during surgical procedures, increasing diagnostic capabilities. A variety of different imaging techniques used in medical applications are reviewed in here.
  • 793
  • 16 Oct 2020
Topic Review
Microbiome in Hidradenitis Suppurativa
Hidradenitis suppurativa is a chronic disease of the pilosebaceous unit. The name of the condition is a testament to the presumed relationship between the disease and the microbiome. The pathophysiology of hidradenitis suppurativa is, however, complex and believed to be the product of a multifactorial interplay between the interfollicular epithelium, pilosebaceous unit, microbiome, as well as genetic and environmental factors.
  • 793
  • 08 Oct 2021
Topic Review
FGFR3-TACCs3 Fusions in Human Glioblastoma
Glioma are the most frequent malignant primary CNS tumors in adults, with an incidence of 5–6 per 100,000 per year, with glioblastoma (with 3.2 per 100,000 per year) being the largest subgroup. The current therapy for glioblastoma is resection followed by radiochemotherapy and their prognosis is always fatal.Oncogenic fusion genes emerged as successful targets in several malignancies, such as chronic myeloic leukemia or lung cancer. Fusion of the fibroblast growth receptor 3 and the transforming acidic coiled coil containing protein – FGFR3-TACC3-fusion is prevalent in 3-4% of human glioblastoma. The fusion protein leads to constitutively activated kinase signaling of FGFR3 and thereby promotes cell proliferation and tumour progression. An overview on clinical and histomolecular features of FGFR3-TACC3-fusion positive glioblastoma is described and the cellular fuction of the fusion protein in glioblastoma cells is highlighted.
  • 792
  • 24 Aug 2022
Topic Review
Race-Based Traumatic Stress
Race-based traumatic stress is the traumatic response to stress following a racial encounter. Robert T. Carter's (2007) theory of race-based traumatic stress implies that there are individuals of color who experience racially charged discrimination as traumatic, and often generate responses similar to post-traumatic stress. Race-based traumatic stress combines theories of stress, trauma and race-based discrimination to describe a particular response to negative racial encounters. Despite the limited research that examines race-based traumatic stress specifically, trauma research suggests that an individual's response to a stressor is highly dependent on that person's perception of the stressor; what one person may experience as traumatic, another person may not experience as such. These differing responses have been found to be strongly associated with each individual's ability to cope with the said stressor. According to Carter, a professor at Columbia University, race-based traumatic stress is an individual's response to racial discrimination as traumatic or outside of their ability to cope. Race-based traumatic stress can be experienced both directly and indirectly and can occur on an interpersonal level, institutional level, or cultural level. As such, research indicates that race-based traumatic stress can be demonstrated as a number of negative outcomes, including psychopathological symptoms, social inequities, and internalized racial oppression. Research has indicated that children, as well as adults, can experience and be impacted by the reaches of race-based traumatic stress. Through direct experience from peers and/or authority figures, as well as indirectly through media exposure and/or bearing witness to the racial discrimination of their parents, research suggests children of color are particularly vulnerable to race-based traumatic stress.
  • 792
  • 14 Oct 2022
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