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Topic Review
Synthesis of CNTs and Biogenesis of BNTs
Nanotubes (NTs) are mainly known as materials made from various substances, such as carbon, boron, or silicon, which share a nanosized tube-like structure. Among them, carbon-based NTs (CNTs) are the most researched group. CNTs, due to their nonpareil electrical, mechanical, and optical properties, can provide tremendous achievements in several fields of nanotechnology. Unfortunately, the high costs of production and the lack of unequivocally reliable toxicity data still prohibit their extensive application. A significant number of intriguing nanotubes-like structures were identified in bacteria (BNTs). The majority of experts define BNTs as membranous intercellular bridges that connect neighboring bacterial cell lying in proximity. Most evidence suggested that bacteria exploit NTs to realize both antagonistic and cooperative intercellular exchanges of cytoplasmic molecules and nutrients. Among other consequences, it has been proposed that such molecular trade, including even plasmids, can facilitate the emergence of new non-heritable phenotypes and characteristics in multicellular bacterial communities, including resistance to antibiotics, with effects of paramount importance on global health.
  • 324
  • 06 Sep 2022
Topic Review
Synthesis of Arylcyanomethylenequinone Oximes
Quinone methides are a class of biologically active compounds that can be used in medicine as antibacterial, antifungal, antiviral, antioxidant, and anti-inflammatory agents. In addition, quinone methides have the potential to be used as pesticides, dyes, and additives for rubber and plastics.
  • 182
  • 17 Oct 2023
Topic Review
Synthesis of Anticancer Polyaromatic Compounds
Bimal Krishna Banik Department of Mathematics and Natural Sciences, College of Sciences and Human Studies, Deanship of Research, Prince Mohammad Bin Fahd University, Al Khobar 31952, KSA; Email: bimalbanik10@gmail.com; bbanik@pmu.edu.sa Synthesis of several polycyclic aromatic compounds is described. Some of these agents have demonstrated selective anticancer activities in vitro and in animal model. Preliminary mechanistic investigations about the cause of bioactivity are also performed.
  • 998
  • 01 Jun 2020
Topic Review
Synthesis of 3,4-Dihydropyrimidin(thio)one Containing Scaffold
The interest in 3,4-dihydropyrimidine-2(1H)-(thio)ones is increasing every day, mainly due to their paramount biological relevance. The Biginelli reaction is the classical approach to reaching these scaffolds, although the product diversity suffers from some limitations. In order to overcome these restrictions, two main approaches have been devised. The first one involves the modification of the conventional components of the Biginelli reaction and the second one refers to the postmodification of the Biginelli products. Both strategies have been extensively revised in this manuscript. Regarding the first one, initially, the modification of one of the components was covered. Although examples of modifications of the three of them were described, by far the modification of the keto ester counterpart was the most popular approach, and a wide variety of different enolizable carbonylic compounds were used; moreover, changes in two or the three components were also described, broadening the substitution of the final dihydropyrimidines. Together with these modifications, the use of Biginelli adducts as a starting point for further modification was also a very useful strategy to decorate the final heterocyclic structure.
  • 980
  • 15 Aug 2022
Topic Review
Synthesis of 2,5-Furandicarboxylic Acid
The most versatile furanic building block for chemical and polymer applications is 2,5-furandicarboxylic acid. However, the classical 2,5-furandicarboxylic acid production methodology has been found to have significant drawbacks that hinder industrial-scale production.  The following content highlights new alternative methods to synthesize 2,5-furandicarboxylic acid that are both more advantageous and attractive than conventional oxidation of 5-hydroxymethylfurfural.
  • 1.1K
  • 19 Jul 2022
Topic Review
Synthesis Approaches of Aza-Dibenzocyclooctyne Derivatives
Cyclooctyne molecules have found wide applications in the strain-promoted azide–alkyne cycloaddition (SPAAC) reactions, which avoid the biotoxicity caused by the use of Cu(I) catalysts. Among the various cyclooctyne systems, dibenzocyclooctyne (DBCO) series have displayed the highest reaction activity.
  • 458
  • 06 May 2023
Topic Review
Synthesis and Vibrational Properties of Conducting Polymers Composites
From composites based on carbon nanotubes (CNTs) and conducting polymers (CPs) to their biggest competitor, namely composites based on graphene or graphene derivate (GD) and CPs, there are many methods of synthesis that influence the morphology and the functionalization inside the composite, making them valuable candidates for EM both inside DSSCs and in supercapacitors devices. From the combination of CPs with carbon-based materials, such as CNT and graphene or GD, the perfect network is created, and so the charge transfer takes place faster and more easily.
  • 560
  • 26 Jan 2024
Topic Review
Synthesis and Structures of MXenes
Among various two−dimensional (2D) materials, MXenes have attracted widespread interest due to their unique surface properties, as well as mechanical, optical, electrical and biocompatible properties, and have been applied in various fields, particularly in the preparation of biosensors, which play a critical role. 
  • 531
  • 19 Oct 2022
Topic Review
Synthesis and Simulation of Nanomaterials
Nanocomposite materials “are composed of several multiple nanomaterials entrapped within a bulk material, which may comprise a combination of a soft and a hard nanomaterial, two soft nanomaterials, or two hard nanomaterials”. 
  • 725
  • 27 Apr 2022
Topic Review
Synthesis and Properties of Pyrazoles
Pyrazole derivatives are a special class of N-heterocyclic compounds (NHCps) bearing a heteroaromatic five-membered ring with two adjacent nitrogen atoms in the annular structure, one pyrrole-type (proton donor) and one pyridine-type (proton acceptor). Pyrazoles can act as weak bases or acids, with possible strength highly dependent on the nature of their substituent groups. The other three positions in the ring permit structural variants starting from the appropriate precursors or using post-functionalization reactions once the pyrazole ring is formed; these variations give the pyrazoles diverse and valuable synthetical, biological, and photophysical properties; indeed, more complex structures with various relevant examples can be formed from them.
  • 1.8K
  • 09 Sep 2022
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