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Topic Review
Functionalized Lanthanide Oxide Nanoparticles
Functionalized lanthanide oxide (Ln2O3) nanoparticles has been used for tumor targeting, medical imaging, and therapy. Among the medical imaging techniques, magnetic resonance imaging (MRI) is an important noninvasive imaging tool for tumor diagnosis due to its high spatial resolution and excellent imaging contrast, especially when contrast agents are used. However, commercially available low-molecular-weight MRI contrast agents exhibit several shortcomings, such as nonspecificity for the tissue of interest and rapid excretion in vivo. Recently, nanoparticle-based MRI contrast agents have become a hot research topic in biomedical imaging due to their high performance, easy surface functionalization, and low toxicity. Among them, functionalized Ln2O3 nanoparticles are applicable as MRI contrast agents for tumor-targeting and nontumor-targeting imaging and image-guided tumor therapy. Primarily, Gd2O3 nanoparticles have been intensively investigated as tumor-targeting T1 MRI contrast agents. T2 MRI is also possible due to the appreciable paramagnetic moments of Ln2O3 nanoparticles (Ln = Dy, Ho, and Tb) at room temperature arising from the nonzero orbital motion of 4f electrons. In addition, Ln2O3 nanoparticles are eligible as X-ray computed tomography contrast agents because of their high X-ray attenuation power. 
  • 696
  • 22 Dec 2021
Topic Review
Functionalized CQDs in Food Analysis
Carbon quantum dots (CQDs) with stable physicochemical properties and excellent optical performances are a kind of emerging and fascinating carbon nanomaterial with size less than 10 nm. The significant advantages of low cytotoxicity and cost make CQDs an ideal raw material for constructing effective sensing devices. The CQDs can be functionalized and combined with other kinds of materials to form the nanostructured composites with unique properties, having a very broad application prospect for related research of many fields. Green-synthesized CQDs have been applied in functional components analysis and monitoring trace harmful substances in food and made remarkable research progress. This entry reviews the relevant sensing applications of CQDs in food components analysis and food safety inspection of recent five years, which can provide significant references for further study of fluorescent and biomimetic sensing of CQDs in this field.
  • 1.6K
  • 28 Oct 2020
Topic Review
Functionalized Chitosan Nanomaterials
Quorum sensing (QS) is the mechanism by which the microbial colonies in a biofilm modulate and intercept communication without direct interaction. Hence, the eradication of biofilms through hindering this communication will lead to the successful management of drug resistance and may be a novel target for antimicrobial chemotherapy. Chitosan shows microbicidal activities by acting electrostatically with its positively charged amino groups, which interact with anionic moieties on microbial species, causing enhanced membrane permeability and eventual cell death. Therefore, nanoparticles (NPs) prepared with chitosan possess a positive surface charge and mucoadhesive properties that can adhere to microbial mucus membranes and release their drug load in a constant release manner. As the success in therapeutics depends on the targeted delivery of drugs, chitosan nanomaterial, which displays low toxicity, can be safely used for eradicating a biofilm through attenuating the quorum sensing (QS).
  • 514
  • 10 Aug 2021
Topic Review
Functionalized Carbon-Based Electrochemical Sensors for Food/Alcoholic Beverage Safety
Food is a necessity in people’s lives. Equally importantly, alcoholic beverages are also highly demanded globally due to the indispensable role they play in cultural, social, and ritual events. However, the production of food and alcoholic beverages suffers from a variety of contaminants, such as toxins, pesticides, antibiotic residues, and heavy metals, which are seriously harmful to human beings. These urgent threats have raised the awareness of the need to improve product quality and safety via developing effective, rapid, and economical monitoring and detecting methods. Fortunately, due to their numerous advantages, including high sensitivity, short response time, low cost, and easy portability, electrochemistry sensors have made huge contributions to ensuring the quality of food and alcoholic beverages. 
  • 477
  • 21 Sep 2022
Topic Review
Functionalized Calixarenes as Promising Antibacterial Drugs
Since the discovery of polyphenolic resins 150 years ago, the study of polymeric compounds named calix[n]arene has continued to progress, and those skilled in the art perfectly know now how to modulate this phenolic ring. Consequently, calix[n]arenes are now used in a large range of applications and notably in therapeutic fields. In particular, the calix[4]arene exhibits multiple possibilities for regioselective polyfunctionalization on both of its rims and offers researchers the possibility of precisely tuning the geometry of their structures. Thus, in the crucial research of new antibacterial active ingredients, the design of calixarenes finds its place perfectly. Out of all the work of the community, there are some excellent activities emerging that could potentially place these original structures in a very good position for the development of new active ingredients.
  • 250
  • 29 Dec 2023
Topic Review
Functionalization Strategies of Nanocarriers
The applications of nanoparticles (NPs) for drug delivery have achieved great achievements and shown enormous advantages. However, the efficient delivery of chemotherapeutic drugs to target cells was still severely restricted by various anatomical and physiological barriers. Consequently, the NPs were designed and functionalized in order to achieve active and specific targeting for promoting the preferential accumulation in tumor tissues, effective uptake by tumor cells, and release of the drug after entering cancer cells.
  • 407
  • 09 Nov 2022
Topic Review
Functionalization of Long-Period Fiber Grating-Based Biosensors
Long-period fiber grating (LPFG)-based biosensors are being increasingly proposed due to their intrinsic advantages over conventional sensors, including their compactness, potential remote control and immunity to electromagnetic interference. When designing a biosensor, it is a key technological step to select the sensitive material suitable for the biological target. Therefore, the functionalization of LPFG-based biosensor is a fundamental step in realizing biochemical applications. Several common functionalization methods are introduced in detailed, such as covalent immobilization of 3-aminopropyltriethoxysilane silanization and graphene oxide  functionalization, and noncovalent immobilization of layer-by-layer assembly method.
  • 368
  • 13 Jan 2023
Topic Review
Functionalization of ETL/Perovskite Interface
Perovskite solar cells (PSCs) have revolutionized the field of photovoltaics, achieving certified power conversion efficiencies reaching 26% at the laboratory scale. High performance, enhanced stability, and long lifetime are prerequisites for the industrialization and commercialization of this class of third-generation photovoltaic technology. The electron transport layer (ETL) plays a pivotal role in obtaining stable perovskite solar cells with a high power conversion efficiency (PCE). It must be characterized by high transparency to visible light, photostability, and compatibility with the perovskite used. Therefore, a thorough comprehension and optimization of the interaction between perovskite materials and TiO2 ETL underlayers, as well as a special focus on the behavior of the corresponding devices, are necessary.
  • 290
  • 15 Aug 2023
Topic Review
Functionalization of Cotton Fabrics with Nanotechnology
Textiles are commonly used in industries and households. The surface modification of textiles to impart multiple functions has recently gained a lot of attention. Researchers have successfully functionalized textiles for antibacterial, self-cleaning, flame retardant, UV protection, and enhanced performance properties. Therefore, high-tech materials and fabric constructions will improve wearer comfort while incorporating distinctive features. Among natural fibers, cotton is the most popular because of its softness, breathability, safety, low cost, regeneration performance, strength, elasticity, biodegradability, and hydrophilicity. Cotton fabric does, however, have some disadvantages, including the possibility of microbial attacks on its fibrous structure, the ease with which creases form, and the loss of mechanical strength. Microorganisms can easily grow and propagate on cotton fabrics because they are able to store humidity and have a high specific surface area. A variety of fields, including health and medicine, have benefited from cotton fibers with antimicrobial properties. Hygienic, functional, durable, and comfortable cotton fabrics are expected in modern times. Utilizing nanotechnology in cotton cloth is a significant challenge in achieving these characteristics and advancements. Nanoparticles have been incorporated into textile finishing stages to address the inherent problems while also imparting functional properties to textile materials.
  • 586
  • 21 Oct 2022
Topic Review
Functionalization of Carbon Nanotubes Surface by Aryl Groups
Arylated nanotubes are characterized by extended solubility, and are widely used in photoelectronics, semiconductor technology, and bioelectrocatalysis. The main emphasis is on arylation methods according to the radical mechanism, such as the Gomberg–Bachmann and Billups reactions, and the decomposition of peroxides. 
  • 497
  • 19 May 2023
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