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Topic Review
Receptor Targeted Molecular Imaging Probes for HCC Theranostics
Hepatocellular carcinoma (HCC) is the sixth most commonly malignant tumor and the third leading cause of cancer-related death in the world, and the early diagnosis and treatment of patients with HCC is core in improving its prognosis. The early diagnosis of HCC depends largely on magnetic resonance imaging (MRI). MRI has good soft-tissue resolution, which is the international standard method for the diagnosis of HCC. However, MRI is still insufficient in the diagnosis of some early small HCCs and malignant nodules, resulting in false negative results. With the deepening of research on HCC, researchers have found many specific molecular biomarkers on the surface of HCC cells, which may assist in diagnosis and treatment. On the other hand, molecular imaging has progressed rapidly in recent years, especially in the field of cancer theranostics. Hence, the preparation of molecular imaging probes that can specifically target the biomarkers of HCC, combined with MRI testing in vivo, may achieve the theranostic purpose of HCC in the early stage.
  • 613
  • 02 Jun 2022
Topic Review
Materials, Devices and Applications of Water Harvesting
Water harvesting technology has been focused, and great merits have been achieved. The design principles of water harvesting technology are commonly inspired by nature. The back of desert beetles possess alternating hydrophilic bumps and hydrophobic surfaces which enable them to harvest water in dry deserts.
  • 472
  • 02 Jun 2022
Topic Review
Polypropylene Extrusion Molding Production Quality
Polypropylene is derived from the reaction of petrochemical propylene gas with a density of 0.89–0.94 g/cm3. It is a lightweight plastic material with a semitransparent white color and has a lower cost than other plastic materials.
  • 737
  • 02 Jun 2022
Topic Review
Metal-Catalyzed Synthesis of the OSe Compounds
Organoselenium (OSe) compounds have recently gained considerable interest as a potential class of organic motifs due to their outstanding applications in synthetic organic and medicinal chemistry and their possible properties in materials science. These are attributed to the exceptional properties of the selenium (Se) element.
  • 630
  • 02 Jun 2022
Topic Review
Synthetic Compartments for Biomedical Applications
Nano- and micrometer-sized compartments composed of synthetic polymers are designed to mimic spatial and temporal divisions found in nature. Self-assembly of polymers into compartments such as polymersomes, giant unilamellar vesicles (GUVs), layer-by-layer (LbL) capsules, capsosomes, or polyion complex vesicles (PICsomes) allows for the separation of defined environments from the exterior. These compartments can be further engineered through the incorporation of (bio)molecules within the lumen or into the membrane, while the membrane can be decorated with functional moieties to produce catalytic compartments with defined structures and functions. Nanometer-sized compartments are used for imaging, theranostic, and therapeutic applications as a more mechanically stable alternative to liposomes, and through the encapsulation of catalytic molecules, i.e., enzymes, catalytic compartments can localize and act in vivo. On the micrometer scale, such biohybrid systems are used to encapsulate model proteins and form multicompartmentalized structures through the combination of multiple compartments, reaching closer to the creation of artificial organelles and cells.
  • 491
  • 02 Jun 2022
Topic Review
Configuration Determinations of Flexible Marine Natural Products
Flexible marine natural products (MNPs), such as eribulin and bryostatin, play an important role in the development of modern marine drugs. However, due to the multiple chiral centers and geometrical uncertainty of flexible systems, configuration determinations of flexible MNPs face great challenges, which, in turn, have led to obstacles in druggability research. To resolve this issue, the comprehensive use of multiple methods is necessary. 
  • 612
  • 01 Jun 2022
Topic Review
Fundaments of Electron Transfer in D-B-A Supramolecular Systems
If we were to sort chemical reactions by their importance for life, electron transfer (ET) would be the best candidate to be ranked first. The reasons for its importance lie in the key role it carries out in major biological processes, such as the electron transport chain and photosynthesis, as well as artificial processes, such as information storage (i.e., photography) and energy conversion (batteries). It is worth noting that ET is ubiquitous in all the branches of chemistry, from organic and biochemistry to physical and inorganic chemistry. The systematic study of the ET processes can be fundamental both for basic knowledge and for strongly applicative reasons.
  • 542
  • 01 Jun 2022
Topic Review
Hierarchical Design of Textile-Based Sensor in Wearable Electronics
Smart textiles have recently aroused tremendous interests over the world because of their broad applications in wearable electronics, such as human healthcare, human motion detection, and intelligent robotics. Sensors are the primary components of wearable and flexible electronics, which convert various signals and external stimuli into electrical signals. While traditional electronic sensors based on rigid silicon wafers can hardly conformably attach on the human body, textile materials including fabrics, yarns, and fibers afford promising alternatives due to their characteristics including light weight, flexibility, and breathability. Of fundamental importance are the needs for fabrics simultaneously having high electrical and mechanical performance. 
  • 488
  • 31 May 2022
Topic Review
Modified Starch-Based Adhesives
Consumer trends towards environmentally friendly products are driving plastics industries to investigate more benign alternatives to petroleum-based polymers. In the case of adhesives, one possibility to achieve sustainable production is to use non-toxic, low-cost starches as biodegradable raw materials for adhesive production. While native starch contains only hydroxyl groups and has limited scope, chemically modified starch shows superior water resistance properties for adhesive applications. Esterified starches, starches with ester substituents, can be feasibly produced and utilized to prepare bio-based adhesives with improved water resistance. Syntheses of esterified starch materials can involve esterification, transesterification, alkylation, acetylation, succinylation, or enzymatic reactions.
  • 2.6K
  • 31 May 2022
Topic Review
Application of Nanomaterial Modified Aptamer-Based Electrochemical Sensor
The electrochemical aptamer sensor (E-apt sensor), which is composed of biometric elements and signal sensors, has attracted more and more attention for this purpose. The signal sensor usually consists of an electrode substrate, modified layer, and electrochemical signal detection system. The most widely used electrode substrates include a gold electrode (AuE), glassy carbon electrode (GCE), indium tin oxide electrode (ITO), reduced graphene electrode (ERGO), and screen-printed electrode (SPE). Nanomaterials are particularly important in the construction of E-apt sensors, which can be used as aptamer carriers or sensitizers to stimulate or inhibit electrochemical signals.
  • 581
  • 31 May 2022
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