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Topic Review
Biography
Topic Review
1,2-cis
glycosylation
Controlling the stereoselectivity of 1,2-cis glycosylation is one of the most challenging tasks in the chemical synthesis of glycans. There are various 1,2-cis glycosides in nature, such as α-glucoside and β-mannoside in glycoproteins, glycolipids, proteoglycans, microbial polysaccharides, and bioactive natural products. In the structure of polysaccharides such as α-glucan, 1,2-cis α-glucosides were found to be the major linkage between the glucopyranosides. Various regioisomeric linkages, 1→3, 1→4, and 1→6 for the backbone structure, and 1→2/3/4/6 for branching in the polysaccharide as well as in the oligosaccharides were identified. To achieve highly stereoselective 1,2-cis glycosylation, including α-glucosylation, a number of strategies using inter- and intra-molecular methodologies have been explored.
462
09 Aug 2023
Topic Review
Electrospun Scaffolds for Tissue Engineering
Electrospun fiber scaffolds offer distinct characteristics, including a high surface area-to-volume ratio, excellent porosity, fiber uniformity, compositional diversity, flexibility, and the ease of functionalization with bioactive molecules. These scaffolds can effectively control the release rate of bioactive molecules, making them promising candidates for delivering antibiotics, proteins, and growth factors.
649
08 Aug 2023
Topic Review
Plant-Based Flocculants as Substituters for Sludge Dewatering
Due to its high water content, sewage sludge dewatering is not just a simple operation; rather, it is a challenging task and a costly management process. Its final handling is usually preceded by several dewatering steps, and among them is the conditioning process known as the flocculation stage, which is carried out using synthetic chemical reagents. Despite the abilities of these additives to reduce sludge volume and extract its bound waters, they are suspected to cause serious environmental and health threats. Their substitution by natural and efficient additives originating from plant extracts could thus be a safe and an eco-friendly alternative, overcoming ecosystem damages.
195
08 Aug 2023
Topic Review
Anti-Cancer Effect of Gypsogenin and Gypsogenic Acid
Gypsogenin possesses a versatile and unique aldehyde group that can be utilized to create covalent interactions with undruggable targets. Gypsogenin carboxamides have demonstrated high cytotoxic activity against breast and lung cancer. The bisamides of gypsogenic acid possess prominent activity as well; however, their anti-leukemic activity is yet to be explored.
251
08 Aug 2023
Topic Review
Metal Oxide-Based Photocatalysis
The improper disposal of toxic and carcinogenic organic substances resulting from the manufacture of dyes, drugs and pesticides can contaminate aquatic environments and potable water resources and cause serious damage to animal and human health and to the ecosystem. In this sense, heterogeneous photocatalysis stand out as one effective and cost-effective water depollution technique. The use of metal oxide nanocomposites (MON), from the mixture of two or more oxides or between these oxides and other functional semiconductor materials, have gained increasing attention from researchers and industrial developers as a potential alternative to produce efficient and environmentally friendly photocatalysts for the remediation of water contamination by organic compounds.
487
08 Aug 2023
Topic Review
Iron Oxides in Bacterial Cellulose Applications
Iron oxide nanoparticles have been investigated due to their suitable characteristics for diverse applications in the fields of biomedicine, electronics, water or wastewater treatment and sensors. Maghemite, magnetite and hematite are the most widely studied iron oxide particles and have ferrimagnetic characteristics.
168
08 Aug 2023
Topic Review
Application of Microfluidic Systems for Neural Studies
Whereas the axons of the peripheral nervous system (PNS) spontaneously regenerate after an injury, the occurring regeneration is rarely successful because axons are usually directed by inappropriate cues. Therefore, finding successful ways to guide neurite outgrowth, in vitro, is essential for neurogenesis. Microfluidic systems reflect more appropriately the in vivo environment of cells in tissues such as the normal fluid flow within the body, consistent nutrient delivery, effective waste removal, and mechanical stimulation due to fluid shear forces. At the same time, it has been well reported that topography affects neuronal outgrowth, orientation, and differentiation.
227
07 Aug 2023
Topic Review
Multilingualism in and out of Films and Stereotypes
Films serve to (re-)create a ‘world’ within the mind of the audience. Additionally, they introduce or reinforce stereotypes portrayed as a reality of the modern world through multiplexity and the strategic use of foreign languages, dialects, and non-native language use, among others. Various concepts of stereotypes can be explored in fiction feature films, especially as film characters are often based on different kinds of stereotypes. Audiovisual texts tend to operate as cultural constructs that reflect and convey certain ideologies within an industry that holds the power to marginalize or belittle voices. Multilingual films highlight the contrasts among and within cultures; hence, they can further exacerbate the marginalization and stereotyping of different cultures and nations, ultimately having damaging effects on society’s perception of different stereotypes, such as race and gender groups, which is shown with the examples from a multilingual film.
634
07 Aug 2023
Topic Review
Microbial PolyHydroxyAlkanoate Biopolymers
PolyHydroxyAlkanoates (PHAs) fulfil every criterion set out in the definition of a natural polymer or a biopolymer. PHA biopolymers, a group of biopolyesters, are found in nature, and they are biosynthesized using renewable carbon in microbes. PHAs are biodegradable, because nature has the tools to convert them into CO2 and water and about 10% organic fertilizer or humus, the same as in the biodegradation of cellulose or cotton.
1.7K
07 Aug 2023
Topic Review
Nanostructured VO
2
Materials and Modulation of Their Properties
The morphology of VO2 depends on synthesis methods, which are primarily categorized solution- and gas-phase-based synthesis methods. For example, sol-gel process and hydrothermal synthesis are representative solution-based chemical approaches, while pulsed laser deposition (PLD), sputtering method, and chemical vapor deposition (CVD) are gas- or vapor-phase synthesis techniques. In previous reports, various techniques for the fabrication of nanostructured VO2 materials have been described in detail.
281
04 Aug 2023
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