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Topic Review
Advantages and Disadvantages of Covalent Inhibitors
The formation of covalent bonds that target proteins can offer drugs diverse advantages in terms of target selectivity, drug resistance, and administration concentration. The most important factor for covalent inhibitors is the electrophile (warhead), which dictates selectivity, reactivity, and the type of protein binding (i.e., reversible or irreversible) and can be modified/optimized through rational designs. Furthermore, covalent inhibitors are becoming more and more common in proteolysis, targeting chimeras (PROTACs) for degrading proteins, including those that are currently considered to be ‘undruggable’.
  • 2.9K
  • 10 May 2023
Topic Review
Advantages and Disadvantages of Fenton Process
The Fenton reaction is primarily based on the idea of the formation of oxidizing radicals, which are created by the catalytic action of Fe2+ on the decomposition of H2O2, added in a certain amount and ratio to water, which also contains various organic substances. Oxidative radicals oxidize the present organic substances to varying degrees during the momentary period of their existence. This Fenton reaction is homogeneous because the catalyst (Fe2+ ion) is dissolved in water. However, the catalyst can also be heterogeneous. 
  • 1.8K
  • 22 Feb 2023
Topic Review
Advantages and Prospects for In Vitro PHA Synthesis
Polyhydroxyalkanoates (PHAs) are a series of structurally diverse storage polyesters that are accumulated by various bacterial species and stored intracellularly in the form of granules. They primarily act as carbon and energy storage compounds to sustain cell survival during starvation.
  • 430
  • 30 May 2023
Topic Review
Advantages of 2D Materials and Cellulose in Biosensors
The use of 2D materials in biosensor applications provides several advantages, including excellent mechanical, optical, and electrical properties. These properties are essential for the development of wearable biosensors that enable real-time monitoring of human health information and accurate measurement of vital signs. Integrating 2D materials into wearable biosensors has expanded opportunities for early detection of life-threatening diseases and continuous health tracking. In addition to 2D materials, cellulose-based biosensors also offer significant benefits. They are cost-effective, highly sensitive, and compatible with portable sensing devices used in biomedical applications. One major advancement in this field is the functionalization of cellulose papers with antibodies, nucleic acids, and nanomaterials in PBBs (paper-based bioassays) and μPADs (microfluidic paper-slip devices). Hence, the application of 2D materials and cellulose in medical diagnostics and biosensors has shown great potential. These materials have unique properties that make them suitable for various applications, including disease detection, real-time monitoring, and point-of-care diagnostics.
  • 436
  • 04 Jan 2024
Topic Review
Advantages of C3N4 with Layered Double Hydroxides Heterojunctions
Environmental pollution has been decreased by using photocatalytic technology in conjunction with solar energy. An efficient method to obtain highly efficient photocatalysts is to build heterojunction photocatalysts by combining graphitic carbon nitride (g-C3N4) with layered double hydroxides (LDHs).
  • 303
  • 08 Dec 2023
Topic Review
Advantages on Waste Management in Hydrogen Industry
The turn to hydrogen as an energy source is a fundamentally important task facing the global energetics, aviation and automotive industries. This step would reduce the negative man-made impact on the environment on the one hand, and provide previously inaccessible power modes and increased resources for technical systems, predetermining the development of an absolutely new life cycle for important areas of technology, on the other. The most important aspect in this case is the development of next-generation technologies for hydrogen industry waste management that will definitely reduce the negative impact of technology on the environment. 
  • 536
  • 23 Nov 2022
Topic Review
Aerogel
Aerogels are one of the most interesting materials of the 21st century owing to their high porosity, low density, and large available surface area. Historically, aerogels have been used for highly efficient insulation and niche applications, such as interstellar particle capture. Recently, aerogels have made their way into the composite universe.
  • 1.4K
  • 14 Feb 2022
Topic Review
Aerogel-Based Plasters
Aerogel has entered the construction field in the last two decades as a component of many insulation products, due to its high thermal performance. Aerogel-based plasters allow the matching of high thermal performance and limited thickness. This makes them suitable when retrofitting an existing building and also when restoring a heritage building. This entry presents the state of the art of the research on aerogel-based plasters as a part of the aerogel-products for the building sector.
  • 1.9K
  • 08 Dec 2020
Topic Review
Aerogels for the Removal of Heavy Metal Ions
Aerogel is a general term referring to novel nanostructured materials characterized by very high porosity and tunable physicochemical properties that are obtained following a sol–gel process and an appropriate drying method. Such novel materials are entering the market in everyday products and a wide portfolio of properties usable for applications in health care, foods, agriculture, energy, and environmental remediation. Bio-based aerogels obtained from renewable resources and biomass are biodegradable and biocompatible due to the natural origin of the polymers, and for this reason, they greatly contribute to the sustainable concept of the bio-economy, offering promising commodities for environmental remediation.
  • 150
  • 22 Jan 2024
Topic Review
Affecting Erosion Factors
Erosion is a major issue since it results in several problems, such as failure/collapse, the degradation of surfaces, severe accidents, and vulnerabilities in many industrial systems and processes. Surface degradation by erosion is a slow but nevertheless continuous and unpreventable process in numerous industries, such as the oil and gas industry; erosion also affects aircraft, steam engines, and the rotor blades of power plant drive turbines, including wet-steam turbines, as well as other turbine plants that operate on wet steam.
  • 701
  • 05 Jul 2022
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