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All Topic Review Biography
Topic Review
Future Healthcare with Ambient Intelligence and IoMT
Imagine technology that is perceptive, adaptable, and perfectly in tune with human needs. This is the promise of Ambient Intelligence (AMI), a groundbreaking advancement in IT with transformative potential across various domains, especially healthcare. By merging the power of Artificial Intelligence (AI) with the Internet of Medical Things (IoMT), AMI creates a dynamic and responsive medical environment. The survey dives deep into the integration of AMI techniques in IoMT, providing essential insights for both researchers and practitioners eager to innovate in the healthcare sector. 
  • 159
  • 19 Jun 2024
Topic Review
Modern Environment as New Secondary Cause of Hypertension
The most important risk factor for cardiovascular disease, the leading cause of death worldwide, is hypertension. Although most cases of hypertension are thought to be essential, the multifactorial associations of the environmental influence on blood pressure seem to play an important role and should be more closely investigated. 
  • 158
  • 22 Dec 2023
Topic Review
Diagnostics of Multi-Order Lung Cancer Models
The early detection and classification of lung cancer is crucial for improving a patient’s outcome. However, the traditional classification methods are based on single machine learning models. Hence, this is limited by the availability and quality of data at the centralized computing server. 
  • 154
  • 06 Nov 2023
Topic Review
HDAC Inhibitors as Antiparasitic Agents
Ongoing therapy for human parasite infections has a few known drugs but with serious side effects and the problem of drug resistance, impelling us to discover novel drug candidates with newer mechanisms of action. Universally, this has boosted the research in the design and development of novel medicinal agents as antiparasitic drugs with a novel mode of action. Histone deacetylase inhibitors (HDACis) are used in a vast variety of diseases due to their anti-inflammatory properties. Drug repurposing strategies have already approved HDACis as cancer therapeutics and are now under investigation for many parasitic infections. Along with the expression of the gene, histone deacetylase (HDAC) enzymes also act as a slice of great multi-subunit complexes, targeting many non-histones, changing systemic and cellular levels signaling, and producing different cell-based specified effects. Zinc (Zn2+)- and nicotinamide adenine dinucleotide (NAD+)-dependent HDACs of parasites play pivotal roles in the alteration of gene expression of parasites. Some of them are already known to be responsible for the survival of several parasites under odd circumstances; thus, targeting them for therapeutic interventions will be novel for potential antiparasitic targets. 
  • 153
  • 25 Jan 2024
Topic Review
External Devices in Rehabilitation Context
Human societies have been trying to mitigate the suffering of individuals with physical impairments, with a special effort in the last century. In the 1950s, a new concept arose, finding similarities between animal exoskeletons, and with the goal of medically aiding human movement (for rehabilitation applications). There have been several studies on using exosuits with this purpose in mind. 
  • 152
  • 23 Nov 2023
Topic Review
Gait Monitoring and Analysis
Gait abnormalities are common in the elderly and individuals diagnosed with Parkinson’s, often leading to reduced mobility and increased fall risk. Monitoring and assessing gait patterns in these populations play a crucial role in understanding disease progression, early detection of motor impairments, and developing personalized rehabilitation strategies. In particular, by identifying gait irregularities at an early stage, healthcare professionals can implement timely interventions and personalized therapeutic approaches, potentially delaying the onset of severe motor symptoms and improving overall patient outcomes.
  • 152
  • 25 Sep 2023
Topic Review
Surgical Treatment of Acute Ankle Injury
Ankle sprains are exceedingly common injuries in both athletes and the general population. They account for 10 to 30% of all sports injuries. Although the vast majority of lateral ankle ligament injuries respond successfully to conservative management, the absolute number of those that progress to chronic lateral ankle instability (CLAI) remains considerably important. This condition is characterized by persistent symptoms and may be associated with short-term and long-term complications and functional deficits. 
  • 151
  • 16 Jan 2024
Topic Review
The Epidemiology of Osteoporosis in Men
Osteoporosis is called the ‘silent disease’ because, although it does not give significant symptoms when it is not complicated, can cause fragility fractures with severe short and long-term consequences until premature death. Men experiencing hip fractures have a higher likelihood of premature death than women during the hospital stay as well as after years from index event. 
  • 146
  • 11 Sep 2023
Topic Review
Developing Cardio-Oncology Programs in the New Era
Modern cancer therapies have achieved a remarkable improvement in overall survival and patients’ quality of life. However, cardiovascular toxicities are still a major concern. A specific Cardio-Oncology unit is key to offering patients with cancer the best approaches to treatment while minimizing adverse cardiac effects. Moreover, this area of medicine requires a large expertise and has limited trials on which to base decision-making. The development of structured Cardio-Oncology programs leads to better patient care and generates scientific evidence that may impact patient’s survival outcomes.
  • 140
  • 02 Jan 2024
Topic Review
Health Transport Demand
Efficient planning and management of health transport services are crucial for improving accessibility and enhancing the quality of healthcare. Specifically, health transport services data from Asturias, spanning a seven-year period, are analyzed with the aim of developing accurate predictive models.
  • 135
  • 31 Jan 2024
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