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Topic Review
Aerosolization of Moulds Particles from Contaminated Materials
Fungi are well known as common contaminants of the indoor environment with the ability to grow on many types of building materials and to subsequently release biological particles into the indoor air. The aerosolization of allergenic compounds or mycotoxins borne by fungal particles or vehiculated by dust may have a direct impact on the occupant’s health. 
  • 349
  • 07 Mar 2023
Topic Review
Aeroterrestrial and Extremophilic Microalgae as Sources in Cosmetics
Microscopic prokaryotic and eukaryotic algae (microalgae), which can be effectively grown in mass cultures, are gaining increasing interest in cosmetics. Up to now, the main attention was on aquatic algae, while species from aeroterrestrial and extreme environments remained underestimated. In these habitats, algae accumulate high amounts of some chemical substances or develop specific compounds, which cause them to thrive in inimical conditions. Among such biologically active molecules is a large family of lipids, which are significant constituents in living organisms and valuable ingredients in cosmetic formulations. Therefore, natural sources of lipids are increasingly in demand in the modern cosmetic industry and its innovative technologies. Among novelties in skin care products is the use of lipid nanoparticles as carriers of dermatologically active ingredients, which enhance their penetration and release in the skin strata. 
  • 538
  • 29 Mar 2022
Topic Review
African Union Strategy on COVID-19 Vaccine
The African Union (AU) vaccination strategy seems to be very optimistic, with major challenges that might hinder the achievement of the main goal of vaccinating 60% of the population, even by 2023. Major health system reforms, as well as better resource allocation, will be crucial for countries to achieve better results.
  • 480
  • 24 Dec 2021
Topic Review Peer Reviewed
Age-Friendly Built Environment
Age-friendly built environments have been promoted by the World Health Organisation (WHO, Geneva, Switzerland) under the Global Age-friendly Cities (AFC) movement in which three domains are related to the built environment. These are: housing, transportation, outdoor spaces and public buildings. The aim is to foster active ageing by optimising opportunities for older adults to maximise their independent living ability and participate in their communities to enhance their quality of life and wellbeing. An age-friendly built environment is inclusive, accessible, respects individual needs and addresses the wide range of capacities across the course of life. Age-friendly housing promotes ageing in familiar surroundings and maintains social connections at the neighbourhood and community levels. Both age-friendly housing and buildings provide barrier-free provisions to minimise the needs for subsequent adaptations. Age-friendly public and outdoor spaces encourage older adults to spend time outside and engage with others against isolation and loneliness. Age-friendly public transport enables older adults to get around and enhances their mobility. For achieving an age-friendly living environment, a holistic approach is required to enable independent living, inclusion and active participation of older adults in society. The eight domains of the AFC movement are not mutually exclusive but overlap and support with one another.
  • 1.8K
  • 13 Apr 2022
Topic Review
Aging and Quality of Life
The aging of the world’s population and the health problems accompanying it are becoming increasingly severe. Healthcare policies in developed countries focus on how to prevent and treat diseases associated with aging and how to maintain quality of life. Typical age-related diseases include deafness, cataracts, osteoarthritis, chronic obstructive pulmonary disease, diabetes mellitus, and dementia. Although the mechanisms by which these diseases develop differ, they are all caused by the accumulation of molecular and cellular damage over time.
  • 267
  • 07 Aug 2023
Topic Review
Aging of BM-MSCs
Aging of bone marrow is a complex process that is involved in the development of many diseases, including hematologic cancers. The results obtained in this field of research, year after year, underline the important role of cross-talk between hematopoietic stem cells and their close environment. In bone marrow, mesenchymal stromal cells (MSCs) are a major player in cell-to-cell communication, presenting a wide range of functionalities, sometimes opposite, depending on the environmental conditions. Although these cells are actively studied for their therapeutic properties, their role in tumor progression remains unclear. One of the reasons for this is that the aging of MSCs has a direct impact on their behavior and on hematopoiesis. In addition, tumor progression is accompanied by dynamic remodeling of the bone marrow niche that may interfere with MSC functions.
  • 693
  • 06 May 2021
Topic Review
Agritourism and Mental-Health in Korea
Green-space exposure can play a crucial role in promoting the health and wellbeing of people. Agritourism is a unique ‘experience’ or ‘activity’ that can allow urban dwellers to participate and reconnect to nature through agriculture on a working farm. Moreover, visiting rural green spaces gives a chance to forget the hectic urban life; it allows the tourist to focus on their own and society’s general wellbeing. Agritourism activities can provide the feel of connection with nature and offer visitors the nostalgia of a “quiet” traditional life. Visiting agritourism sites and engaging in the associated activities can improve the perceived immediate mood. In addition, perceived wellbeing might contribute to such immediate mood-boosting.
  • 986
  • 23 Aug 2021
Topic Review
AI and Neural Network Algorithms
Al increases the potential of Micro-Electro-Mechanical System biosensors and opens up new opportunities for automation, consumer electronics, industrial manufacturing, defense, medical equipment, etc. Micro-Electro-Mechanical System microcantilever biosensors are currently making their way into the daily lives and playing a significant role in the advancement of social technology. Micro-Electro-Mechanical System biosensors with microcantilever structures have a num- ber of benefits over conventional biosensors, including small size, high sensitivity, mass production, simple arraying, integration, etc. These advantages have made them one of the development avenues for high-sensitivity sensors. The next generation of sensors will exhibit an intelligent development trajectory and aid people in interacting with other objects in a variety of scenario applications as a result of the active development of artificial intelligence (AI) and neural networks. A neural algorithm application in Micro-Electro-Mechanical System microcantilever biosensors is anticipated through the associated application of the principal com-ponent analysis approach. Researchers investigation has more scientific study value, because there are currently no favorable reports on the market regarding the use of AI with Micro-Electro-Mechanical System microcantilever sensors.
  • 347
  • 13 Sep 2022
Topic Review
AI and Radiomics in Bladder Cancer
The advent of artificial intelligence (AI) and radiomics in oncology marks a pivotal moment in the evolution of personalized medicine, particularly in the diagnosis and treatment of urological cancers such as bladder, kidney, and prostate cancer. These cutting-edge technologies are reshaping the foundations of cancer care, heralding a paradigm shift towards precision-driven methods. The diagnosis and treatment of bladder cancer have been profoundly transformed by the recent advancements in AI and radiomics.
  • 62
  • 27 Feb 2024
Topic Review
AI Application in Rare Diseases
Emerging machine learning (ML) technologies have the potential to significantly improve the research and treatment of rare diseases, which constitute a vast set of diseases that affect a small proportion of the total population. Artificial Intelligence (AI) algorithms can help to quickly identify patterns and associations that would be difficult or impossible for human analysts to detect. Predictive modeling techniques, such as deep learning, have been used to forecast the progression of rare diseases, enabling the development of more targeted treatments. Moreover, AI has also shown promise in the field of drug development for rare diseases with the identification of subpopulations of patients who may be most likely to respond to a particular drug.
  • 396
  • 29 Mar 2023
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