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Topic Review
Biliary Atresia
The term biliary atresia has substituted the original term of “extrahepatic biliary atresia”, which has been in use for several generations. The concept was related to the often-identified absence of gallbladder with an obliterated cord at the site the extrahepatic biliary system. It is now known that biliary atresia is a necro-inflammatory and fibro-obliterative process of both intrahepatic and extrahepatic biliary tract.
  • 613
  • 11 Feb 2022
Topic Review
Bio-Preservation of Meat by Lactic Acid Bacteria Strains
Meat and some meat products are highly perishable due to their high-water content, pH, and high content of nutrients. Therefore, spoilage control in these products is one of the critical challenges in the food industry. On the other hand, the increasing widespread awareness about the undesirable effects of synthetic preservatives has promoted the breakthrough of the use of natural compounds or bio-preservation technology. Bio-preservation implies the application of microorganisms or their metabolites to extend the shelf life of food products. In this regard, according to the ancient and safe use of fermentation by lactic acid bacteria (LAB), their application in the bio-preservation of meat and meat products is gaining more attention.
  • 297
  • 11 Jul 2023
Topic Review
Bio-Signals in Medical Applications
Artificial Intelligence (AI) has broadly connected the medical field at various levels of diagnosis based on the congruous data generated. Different types of bio-signal can be used to monitor a patient’s condition and in decision making. Medical equipment uses signals to communicate information to care staff. AI algorithms and approaches will help to predict health problems and check the health status of organs, while AI prediction, classification, and regression algorithms are helping the medical industry to protect from health hazards. The early prediction and detection of health conditions will guide people to stay healthy.
  • 2.6K
  • 03 Mar 2022
Topic Review
Bioactive Mycocompounds of Selected Medicinal Mushrooms for HPV
Medicinal mushrooms have been used as a medicinal tool for many centuries and, nowadays, are used in the prevention and therapy of various diseases, including as an adjunct to cancer treatment. It is estimated that 14–16% of global cancer cases are caused by infectious events; one well-known infectious agent that leads to cancer is the human papillomavirus (HPV). HPV is responsible for more than 99.7% of cervical cancer cases and also may play a role in vaginal, vulvar, penile, anal, rectal, and oropharyngeal carcinogenesis. Coriolus versicolor, a basidiomycetes class mushroom, consists of glycoproteins called polysaccharide-K (PSK) and polysaccharopeptide (PSP), which are mainly responsible for its effectiveness in the fight against a variety of cancers. Its beneficial effect lies in its ability to arrest different phases of the cell cycle, immunomodulation or induction of apoptosis. Coriolus versicolor extractcan reduces BCL-2 expression or increases the expression of p53 tumour suppressor genes in breast tumour cell lines. Inhibition of proliferation was also demonstrated with HeLa cells, while cervical cytology abnormalities improved in patients who locally applied Coriolus versicolor-based vaginal gel. Coriolus versicolor extract itself, and also its combination with another medicinal mushroom, Ganoderma lucidum, leads to improved HPV clearance in HPV cervical or oral-positive patients. Medicinal mushrooms can also increase the effectiveness of vaccination.
  • 441
  • 11 Apr 2023
Topic Review
Biochar in Soil Systems Regulation
Biochar is a carbon-rich material prepared from the pyrolysis of biomass under various conditions. Recently, biochar drew great attention due to its promising potential in climate change mitigation, soil amendment, and environmental control. Obviously, biochar can be a beneficial soil amendment in several ways including preventing nutrients loss due to leaching, increasing N and P mineralization, and enabling the microbial mediation of N2O and CO2 emissions.
  • 758
  • 25 Jun 2021
Topic Review
Biocidal Action of Hydrogen Peroxide Vapour and Mechanism
Disinfection is described as a process that eliminates many or all pathogenic microorganisms on inanimate objects, with the exception of bacterial endospores. Disinfection is usually carried out by chemical or physical means. Among other settings, disinfection is of utmost importance in hospital environments due to pathogens living on hospital surfaces being the direct cause for hospital-acquired infections (HAIs). However, the presence of a wide range of pathogens and biofilms, combined with the indiscriminate use of antibiotics, presents infection control teams in healthcare facilities with ongoing challenges in the selection of biocides and application methods. This necessitates the development of biocides and innovative disinfection methods that overcome the shortcomings of conventional methods. The use of hydrogen peroxide vapour to be a superior alternative to conventional methods. Hydrogen peroxide vapour to be very close to an ideal disinfectant due to its proven efficacy against a wide range of microorganisms, safety to use, lack of toxicity concerns and good material compatibility.
  • 296
  • 14 Mar 2024
Topic Review
BioFilms
Biofilms are aggregates formed as a protective survival state by microorganisms to adapt to the environment and can be resistant to antimicrobial agents and host immune responses due to chemical or physical diffusion barriers, modified nutrient environments, suppression of the growth rate within biofilms, and the genetic adaptation of cells within biofilms. With the widespread use of medical devices, medical device-associated biofilms continue to pose a serious threat to human health, and these biofilms have become the most important source of nosocomial infections. However, traditional antimicrobial agents cannot completely eliminate medical device-associated biofilms. New strategies for the treatment of these biofilms and targeting biofilm infections are urgently required. Several novel approaches have been developed and identified as effective and promising treatments.
  • 1.3K
  • 13 Apr 2021
Topic Review
Biofilms on Medical Devices
Biofilm is complex and consists of bacterial colonies that reside in an exopolysaccharide matrix that attaches to foreign surfaces in a living organism. Biofilm frequently leads to nosocomial, chronic infections in clinical settings. Since the bacteria in the biofilm have developed antibiotic resistance, using antibiotics alone to treat infections brought on by biofilm is ineffective. 
  • 362
  • 06 Jul 2023
Topic Review
Biological Activities of Genus Scutellaria
Scutellaria (Lamiaceae) comprises over 360 species. Based on its morphological structure of calyx, also known as Skullcap, it is herbaceous by habit and cosmopolitan by habitat. The species of Scutellaria are widely used in local communities as a natural remedy. The genus contributed over three hundred bioactive compounds mainly represented by flavonoids and phenols, chemical ingredients which serve as potential candidates for the therapy of various biological activities.
  • 434
  • 21 Jul 2022
Topic Review
Biological Effects and Mechanisms of Electromagnetic Radiation
Modern humanity wades daily through various radiations, resulting in frequent exposure and causing potentially important biological effects. Among them, the brain is the organ most sensitive to electromagnetic radiation (EMR) exposure.
  • 5.0K
  • 31 Aug 2022
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