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Topic Review
Epidemiological Scenario of and Gastric Cancer in Chile
Helicobacter pylori (H. pylori) is a Gram-negative, microaerophilic bacterium that colonizes the gastric mucosa of more than 50% of the world’s population. In 1994, the International Agency for Research on Cancer classified it as a Group I carcinogen. Infection can be acquired in childhood and persist asymptomatically throughout life. H. pylori causes chronic gastritis. This can lead to peptic ulcers as well as premalignant lesions such as atrophic gastritis, intestinal metaplasia, and dysplasia, which can eventually trigger gastric cancer. Atrophic gastritis is the first step in the premalignant cascade and is characterized by the loss of gastric glandular cells, resulting in reduced acid production and an increase in pH levels. Intestinal metaplasia refers to the transformation of the gastric epithelium into an intestinal-type epithelium, which can be complete or incomplete, depending on the presence of goblet cells among the epithelial cells. 
  • 257
  • 07 Feb 2024
Topic Review
GP's Perspectives on Weight Loss Dietary Advice
General practitioners (GPs) play a crucial role in guiding patients’ health behaviors, including advising on weight loss. GPs have access to a variety of lifestyle, medical, and surgical approaches to weight loss to assist their patients. 
  • 257
  • 31 Jul 2023
Topic Review
Food Regimes on Oxidative Stress
The existence of significant differences between two dietary regimes (omnivorous vs. semi-vegetarian) with reference to some oxidative stress markers (SOD, GPx, TRxR, GR, AGEs, and AOPPs) using non-parametric combination methodology based on a permutation test.
  • 256
  • 07 Nov 2023
Topic Review
Pathological Mechanisms of Mitochondria in Brain Disease
Mitochondria play a vital role in maintaining cellular energy homeostasis, regulating apoptosis, and controlling redox signaling. Dysfunction of mitochondria has been implicated in the pathogenesis of various brain diseases, including neurodegenerative disorders, stroke, and psychiatric illnesses.
  • 256
  • 24 Oct 2023
Topic Review
Theranostics Using Indocyanine Green Lactosomes
Lactosomes™ are biocompatible nanoparticles that can be used for cancer tissue imaging and drug delivery. Lactosomes are amphiphilic micelles in which the particle size can be controlled in the range of 20 to 100 nm. Lactosomes can also be loaded with imaging probes and anticancer agents. Indocyanine green-loaded lactosomes accumulate in cancer tissues and function as a photosensitizer, which simultaneously enables diagnosis and photodynamic therapy. 
  • 255
  • 17 Aug 2022
Topic Review
Self-Testing to Reduce HIV in Transgender Women
So far, the rate of HIV-positive people who do not know their sero-status is about 14% and the percentage is higher among transgender women (TGW). They represent one of the most vulnerable groups to infection. HIV self-testing (HIVST) may be a way to reduce transmission of the virus. 
  • 254
  • 10 Aug 2022
Topic Review
Status of Chinese Children with Autism Spectrum Disorder
Autism spectrum disorder (ASD) is characterized by an individual’s deficits in social communication and interaction, accompanied by repetitive and stereotyped behaviors and a restricted scope of interests. The prevalence of ASD among Chinese children over the past two decades has attracted substantial attention from practitioners, researchers, and policymakers. 
  • 255
  • 31 May 2023
Topic Review
Nutrition Situation in Jordan
Jordan is witnessing an escalating pace of nutrition transition, which may be associated with an increased burden of malnutrition and related non-communicable diseases. The nutrition situation in Jordan is analyzed by exploring specific nutrition indicators, namely infant and young child feeding, low birthweight, micronutrient deficiencies, anthropometric indicators, and food consumption patterns. Results showed that although most children were ever breastfed and early initiation of breastfeeding had a two-fold increasing trend, rates of exclusive breastfeeding below 6 months of age and continued breastfeeding until two years of age were low. Complementary feeding indicators, particularly minimum diet diversity and minimum acceptable diet standards, were suboptimal. An overall low burden of stunting, wasting, and underweight among children under 5 years and remarkable progress in optimizing iodine status among school-aged children were reported. Conversely, the burden of low birthweight and overweight/obesity exacerbated, coexisting with anemia, vitamin A deficiency, and vitamin D deficiency. Overall, fruit and vegetable consumption were inadequate. The consumption of soft drinks and salt on the other hand was higher than recommended. The double burden of malnutrition in Jordan is acknowledged and recommends the prioritization and evaluation of interventions towards improving the population’s nutritional status and achieving nutrition targets.
  • 253
  • 17 Jul 2023
Topic Review
Ecological Factors of VE Popularity Speed in West-Africa
Encephalitis is an inflammation of the brain, often caused by an autoimmune reaction, or in most cases because of a direct viral, bacterial, or parasitic infection. Viral encephalitides (VE) presents a significant public health concern globally, especially in West Africa. There are more than five hundred known arthropod-borne viruses (arboviruses), with over a hundred of them identified to cause encephalitic diseases in humans and animals, giving rise to a tremendous burden of the diseases and socioeconomic strains in tropical and subtropical regions worldwide. 
  • 252
  • 21 Sep 2023
Topic Review
Composition of Dental Waste
Dental waste can be broadly divided into three categories: infectious waste, non-infectious waste, and domestic-type waste. Infectious waste contains materials contaminated with blood or other infectious mouth fluids, amalgam, and sharps, whereas non-infectious dental waste is devoid of human fluid contamination but can be potentially toxic due to the presence of amalgams, acids, metal dust, resins, etc. Suspended particulates in dental wastewater are another likely source of contamination. Appropriate segregation of this waste is essential for containing infections during waste processing. New-generation dental materials, such as nanomaterials, resin-based composites, and ceramics, are finding increasing applications in a variety of dental procedures as antimicrobial, restorative, and therapeutic agents. While incineration and landfilling have been used for processing traditional dental waste, the presence of novel materials in dental waste raises several additional concerns. Novel single/multistage recycling approaches need to be developed for dental waste towards resource recovery, thus minimizing incineration and landfilling to the extent possible.
  • 252
  • 21 Nov 2023
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