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Topic Review
Natural Products for Non-Alcoholic Fatty Liver Disease Treatment
Plants are an untapped natural resource; their secondary metabolites take part in a variety of pharmacological activities, making them an essential ingredient in the synthesis of novel medications and the source of reserve resources in this process. Hepatitis and liver cancer are two conditions that can result from non-alcoholic fatty liver disease (NAFLD). NAFLD is a condition that now affects a significant section of the global population. There is a need for preventative action on predisposing factors. Due to their effectiveness and few side effects, herbal medications are frequently utilized for the prevention and treatment of NAFLD.
  • 206
  • 27 Feb 2024
Topic Review
Natural Products for Alleviating Non-alcoholic Fatty Liver Disease
Non-alcoholic fatty liver disease (NAFLD) is the most common form of liver disease all over the world due to the obesity pandemic; currently, therapeutic options for NAFLD are scarce, except for diet recommendations and physical activity. NAFLD is characterized by excessive accumulation of fat deposits (>5%) in the liver with subsequent inflammation and fibrosis. Studies in the literature show that insulin resistance (IR) may be considered as the key mechanism in the onset and progression of NAFLD. Using natural products, for example, spirulina, oleuropein, garlic, berberine, resveratrol, curcumin, ginseng, glycyrrhizin, coffee, cocoa powder, epigallocatechin-3-gallate, and bromelain, as an alternative approach in the treatment of NAFLD has drawn growing attention among physicians.
  • 704
  • 06 Jan 2022
Topic Review
Natural Polyphenols and Cancer
Natural compounds with anticancer properties are capable of killing transformed or cancerous cells without being toxic to healthy cells. Most fruits and vegetables consumed with food are made up of bioactive molecules belonging to the family of polyphenols, a group of natural compounds widely distributed in the plant kingdom; this group is varied, and to date, more than 8000 phenolic structures are known. Polyphenols are classified according to chemical structure, and their subdivision is represented in.
  • 384
  • 04 Nov 2021
Topic Review
Natural Milk Microbiota
Profound bioactivities of raw breastmilk include benefits attributed to the dense and diverse natural microbiota, termed natural microbiota hereafter. Infants benefit from breastfeeding not just nutritionally, but by both ‘seeding and feeding’ the infant gut , providing microbes that seed the naïve gastrointestinal (GI or gut) ecosystem and nutritive components that feed both infant and microbial cells.
  • 585
  • 11 Nov 2021
Topic Review
Natural Language Processing for the COVID-19 Pandemic
The COVID-19 pandemic is the most devastating public health crisis and has affected the lives of billions of people worldwide in unprecedented ways. Compared to pandemics of this scale in the past, societies are now equipped with advanced technologies that can mitigate the impacts of pandemics if utilized appropriately. However, opportunities are not fully utilized, particularly at the intersection of data science and health. Health-related big data and technological advances have the potential to significantly aid the fight against such pandemics, including the pandemic’s ongoing and long-term impacts. Specifically, the field of natural language processing (NLP) has enormous potential at a time when vast amounts of text-based data are continuously generated from a multitude of sources, such as health/hospital systems, published medical literature, and social media. Effectively mitigating the impacts of the pandemic requires tackling challenges associated with the application and deployment of NLP systems.
  • 783
  • 24 Nov 2022
Topic Review
Natural Ingredients from Trás-os-Montes Region
The natural cosmetics market has grown since consumers became aware of the concept of natural-based ingredients. A significant number of cosmetics have an ecological impact on the environment and carry noxious and chemically potent substances. Thus, the use of natural and organic cosmetics becomes increasingly important since it is clear that topical treatment withcosmeceuticals can help improve skin rejuvenation. A substantial investigation into the benefits that fruits and plants can bring to health is required. Studies have shown that antigenotoxic properties are linked to anti-aging properties. Several studies have shown potential antigenotoxicity in natural ingredients such as Almonds (Prunus dulcis), Elderberry (Sambucus nigra), Olives (Olea europaea), and Grapes (Vitis vinifera). This review presents an overview of research conducted on these natural ingredients, the most common in the Northeast of Portugal. This region of Portugal possesses the most organic farmers, and ingredients are easily obtained. The Northeast of Portugal also has climatic, topographic, and pedological differences that contribute to agricultural diversity.
  • 368
  • 24 Sep 2021
Topic Review
Natural Antimicrobial Agents for Wound Infections Treatment
The rising prevalence of drug-resistant bacteria underscores the need to search for innovative and nature-based solutions. One of the approaches may be the use of plants that constitute a rich source of miscellaneous compounds with a wide range of biological properties. Natural products are one of the most promising and intensively examined agents to combat the consequences of the overuse and misuse of classical antibiotics.
  • 176
  • 17 Feb 2024
Topic Review
Nanotechnologies in Obstetrics and Cancer during Pregnancy
Nanotechnology, the art of engineering structures on a molecular level, offers the opportunity to implement new strategies for the diagnosis and management of pregnancy-related disorders. Although nanotechnology has been on the bench for many years, most of the studies in obstetrics are preclinical. Ongoing research spans from the development of diagnostic tools, including optimized strategies to selectively confine contrast agents in the maternal bloodstream and approaches to improve diagnostics tests to be used in obstetrics, to the synthesis of innovative delivery nanosystems for therapeutic interventions. Using nanotechnology to achieve spatial and temporal control over the delivery of therapeutic agents (e.g., commonly used drugs, more recently defined formulations, or gene therapy-based approaches) offers significant advantages, including the possibility to target specific cells/tissues of interest (e.g., the maternal bloodstream, uterus wall, or fetal compartment). This characteristic of nanotechnology-driven therapy reduces side effects and the amount of therapeutic agent used. However, nanotoxicology appears to be a significant obstacle to adopting these technologies in clinical therapeutic praxis. 
  • 372
  • 30 Oct 2022
Topic Review
Nanoparticles for Breast Cancer Diagnosis
Breast cancer (BC) is the foremost common cause of death in women, and its early diagnosis will help treat and increase patients’ survival. BC is about 100 times more common in women than in men. The risk factors for BC are alcohol intake, body mass index, hormone replacement therapy with estrogen and progesterone, radiation exposure, early and late menarche, and late age in first childbirth. Also, current age (increasing age increases the risk of developing BC), history of BC, breast biopsy, cytology, family history, inherited mutation in the BRCA1 or BRCA2 gene, and the risk of BC and interval cancers is four to six times higher in women with very dense breast (DB) tissue than in those with fatty breasts.
  • 253
  • 26 Dec 2023
Topic Review
Nanomaterials for Industrial Wastewater Treatment
Industrial wastewater originating from various industries contributes as a major source of water pollution. This pollutant poses a severe threat to the environment. Recent years saw nanomaterials as a potential candidate for pollutants removal. Nowadays, a range of cost-effective nanomaterials is available with unique properties.
  • 1.2K
  • 22 Jul 2021
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