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Topic Review
Electrochemical  Lactate (Bio)Sensor Transduction Approaches
Monitoring of lactate is spreading from the evident clinical environment, where its role as a biomarker is notorious, to the agrifood ambit as well. In the former, lactate concentration can serve as a useful indicator of several diseases (e.g., tumour development and lactic acidosis) and a relevant value in sports performance for athletes, among others. In the latter, the spotlight is placed on the food control, bringing to the table meaningful information such as decaying product detection and stress monitoring of species. No matter what purpose is involved, electrochemical (bio)sensors stand as a solid and suitable choice.
  • 566
  • 22 Nov 2022
Topic Review
Mechanism of Actions of Long Non-Coding RNAs
Long non-coding RNAs (lncRNAs) are master regulators of almost all biological processes. LncRNAs perform their function mostly through different chromatin-based mechanisms such as signals, decoys, guides, and scaffolds in chromatin remodelling. LncRNAs play a major role in genomic imprinting. 
  • 565
  • 22 Nov 2022
Topic Review
T Cells in Metabolic Diseases
Metabolic disease is a kind of multi-system abnormal disease which is manifested by diseases or disorders that disrupt normal metabolism, including hyperglycemia, dyslipidemia, hypertension, obesity, and insulin resistance, and leads to a dramatic increase in the occurrence of cardiovascular diseases such as acute myocardial infarction and stroke. T cells are involved in the inflammatory response, which can also regulate the development of metabolic diseases, CD4+ T cells and CD8+ T cells are mainly responsible for the role.
  • 545
  • 22 Nov 2022
Topic Review
Heart Health and Mental Wellbeing
Indigenous peoples have thrived since time immemorial across North America; however, over the past three to four generations there has been a marked increase in health disparities amongst Indigenous peoples versus the general population. Heart disease and mental health issues have been well documented and appear to be interrelated within Indigenous peoples across Canada.
  • 331
  • 22 Nov 2022
Topic Review
Epidemiological Investigations on Health Effects in Toner-Manufacturing Workers
Adverse health effects can occur in occupational engagements in various industries, and there have been several reports on the contamination of work environments by long-term exposure to chemicals such as heavy metals and organic solvents. Dust has long caused serious health problems at workplaces such as coal mines, tunnel construction, arc welding, metal grinding, foundries, and quarries.
  • 444
  • 22 Nov 2022
Topic Review
Circulating Tumor Cells in Colorectal Cancer
Circulating tumor cells (CTCs)  are intact cells separated from the primary tumor or metastases and released into the peripheral circulation. They were observed and discovered for the first time in 1869 in the blood of a patient with breast cancer. CTCs mainly originate from solid tumors of epithelial origin (breast, prostate, colon, and lung). CTCs are nucleated and express epithelial cell adhesion molecules (EpCAM) and/or cytokeratins (CK) in the cytoplasm without coexpressing the common leukocyte antigen CD45. It is known today that there is significant heterogeneity in cell species and surface markers, which represents a challenge in isolating all clinically relevant subpopulations of CTCs.
  • 497
  • 22 Nov 2022
Topic Review
Electrochemical Biosensors for Genetically Modified Crops Detection
Food safety issues are directly related to people's quality of life, so there is a need to develop efficient and reliable food contaminants’ detection devices to ensure the safety and quality of food. Electrochemical biosensors have the significant advantages of miniaturization, low cost, high sensitivity, high selectivity, rapid detection, and low detection limits using small amounts of samples, which are expected to enable on-site analysis of food products.
  • 570
  • 21 Nov 2022
Topic Review
Stress of Moving Homes
Moving homes has long been considered stressful, but how stressful is it? Researches try to utilise a micro-level individual dataset in the New Zealand Government’s Integrated Data Infrastructure (IDI) to reconstruct the Social Readjustment Rating Scale (SRRS) and thereby measure stress at a whole-of-population level. The effects of residential mobility on people’s mental well-being in the context of their stress-of-moving homes are examined.
  • 354
  • 21 Nov 2022
Topic Review
Research Trends of Physical Activity during Pregnancy
Physical activity (PA) during pregnancy has been proven beneficial to pregnant women, with a significant effect on ameliorating many severe gestational complications. Improvement of sedentary behaviour, lifestyle intervention through leisure-time PA, and preterm care are major research frontiers and have received extensive attention. 
  • 281
  • 21 Nov 2022
Topic Review
Monkeypox Epidemiology
Monkeypox virus (MPXV) belongs to the Poxviridae species. In the Poxviridae family, the Orthopoxvirus gene contains two enclosed strands of virus DNA (replicating in the cytoplasm and not the nucleus) and is called the monkeypox virus (MPXV).
  • 342
  • 18 Nov 2022
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