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Topic Review
Electrical Stimulation Exercise for People with SCI
Electrical stimulation exercise has become an important modality to help improve the mobility and health of individuals with spinal cord injury (SCI). Electrical stimulation is used to stimulate peripheral nerves in the extremities to assist with muscle strengthening or functional activities such as cycling, rowing, and walking. Electrical stimulation of the peripheral nerves in the upper extremities has become a valuable tool for predicting the risk of hand deformities and rehabilitating functional grasping activities.
  • 424
  • 08 Jun 2023
Topic Review
Deep Learning Aided Neuroimaging for Brain Monitoring
Deep learning has shown tremendous potential in the field of neuroimaging and brain regulation. Neuroimaging techniques such as MRI, CT, PET/CT, EEG/MEG, optical imaging, and other imaging modalities generate large amounts of comprehensive and complex data, which can be challenging to analyze and interpret. Deep learning techniques such as convolutional neural networks (CNNs), recurrent neural networks (RNNs), and generative adversarial network (GAN) have been proven to be effective in extracting meaningful information from these data and transforming the neuroimaging from qualitative to quantitative imaging modality. The aforementioned information is merged with additional patient data and processed using advanced bioinformatics software to create models that could potentially enhance the accuracy in the diagnosis, prognosis, and prediction for brain monitoring and regulation.
  • 475
  • 07 Jun 2023
Topic Review
Marine Cyanobacterial Peptides in Neuroblastoma
Neuroblastoma is the most prevalent extracranial solid tumor in pediatric patients, originating from sympathetic nervous system cells. Metastasis can be observed in approximately 70% of individuals after diagnosis, and the prognosis is poor. The current care methods used, which include surgical removal as well as radio and chemotherapy, are largely unsuccessful, with high mortality and relapse rates. Marine cyanobacteria are a key source of physiologically active metabolites, which have recently received attention owing to their anticancer potential. Marine peptides possess several advantages over proteins or antibodies, including small size, simple manufacturing, cell membrane crossing capabilities, minimal drug–drug interactions, minimal changes in blood–brain barrier (BBB) integrity, selective targeting, chemical and biological diversities, and effects on liver and kidney functions.
  • 407
  • 05 Jun 2023
Topic Review
MicroRNAs’ Role in the Treatment of Subarachnoid Hemorrhage
Subarachnoid hemorrhage (SAH) is most commonly seen in patients over 55 years of age and often results in a loss of many productive years. SAH has a high mortality rate, and survivors often suffer from early and secondary brain injuries. Understanding the pathophysiology of the SAH is crucial in identifying potential therapeutic agents. One promising target for the diagnosis and prognosis of SAH is circulating microRNAs, which regulate gene expression and are involved in various physiological and pathological processes.
  • 255
  • 05 Jun 2023
Topic Review
The Applications of Artificial Intelligence in Screening
Artificial intelligence (AI) is a field of study that attempts to replicate natural human intelligence in machines. The machines can then independently perform activities that would otherwise require human intelligence. AI can be broken down into several subsets, such as machine learning (ML) and deep learning (DL). Primary care has the potential to be transformed by artificial intelligence (AI) and, in particular, machine learning (ML). Healthcare professionals can identify diseases at an early and curable stage by using ML models to examine medical pictures, diagnostic modalities, and spot patterns that may suggest disease or anomalies. Before the onset of symptoms, ML can be used to identify people at an increased risk of developing specific disorders or diseases. ML algorithms can assess patient data such as medical history, genetics, and lifestyle factors to identify those at higher risk. This enables targeted interventions such as lifestyle adjustments or early screening. 
  • 270
  • 05 Jun 2023
Topic Review
Unsilencing the Echoes of Historical Trauma
Indigenous communities in North America have distinct colonial histories with their own story of how their ancestors were able to survive the mass effort to take their land, resources, language, culture, and sometimes even their lives. These stories have been passed down orally and through the DNA of the descendants of survivors via epigenetics. The Historical Loss Scale (HLS) and Historical Loss Associated Symptoms Scale (HLASS) are two validated scales that measure historical trauma among Native Americans.
  • 287
  • 05 Jun 2023
Topic Review
The Association between Music and Language in Children
Music and language are two complex systems that specifically characterize the human communication toolkit.
  • 276
  • 05 Jun 2023
Topic Review
Diet in Asthma
Asthma is a chronic respiratory disease that impacts millions of people worldwide. Several dietary factors have been recognized as potential contributors to the development and severity of asthma for its inflammatory and oxidative effects. Some food groups such as fruits and vegetables, whole grains, and healthy fats appear to exert positive effects on asthma disease. On the other hand, a high consumption of dietary salt, saturated fats, and trans-fat seems to have the opposite effect. 
  • 422
  • 02 Jun 2023
Topic Review
Diagnosis of Low Back Pain
Low back pain ranks as the leading cause of years lived with disability worldwide. Although best practice guidelines share a consistent diagnostic approach for the evaluation of patients with low back pain, confusion remains as to what extent patient history and physical examination findings can inform management strategies.
  • 226
  • 01 Jun 2023
Topic Review
Relationship between Personality and Intelligence
There are two major theories in this area. First, compensation theory suggests that conscientiousness acts as a “coping/reimbursing strategy” for less intelligent, but ambitious and competitive, people in particular settings. Thus, relatively less intelligent individuals may become more methodical, organised, thorough, and persistent (i.e., conscientious) to compensate for their relative lack of intelligence in a highly competitive educational or work environment. That is, they can achieve as much as bright people by simply working harder and smarter. Alternatively, relatively more intelligent people may tend to succeed based on their cognitive efficiency, rather than strenuous effort or persistent effort and organisation.
  • 291
  • 01 Jun 2023
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