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Topic Review
Southern Spotted Skunk
The Southern Spotted Skunk (Spilogale angustifrons) is a small and elusive carnivore known for its distinctive coat pattern featuring conspicuous spots and stripes. Inhabiting various regions of the southern United States and parts of Central America, this species exhibits remarkable adaptability to diverse habitats, ranging from woodlands and grasslands to urban areas. Despite its diminutive size, the Southern Spotted Skunk plays a significant role in local ecosystems, displaying nocturnal behavior and an omnivorous diet.
  • 238
  • 04 Feb 2024
Topic Review
Angolan Genet
The Angolan Genet (Genetta angolensis), indigenous to the southwestern regions of Africa, is a captivating small carnivore that belongs to the Genet family. Recognized for its distinctive coat pattern and slender physique, this elusive species navigates a range of habitats, from woodlands to savannas, showcasing its adaptability in diverse ecosystems. With its nocturnal habits and agile climbing skills, the Angolan Genet remains a subject of interest for researchers and wildlife enthusiasts exploring the rich biodiversity of the African continent.
  • 256
  • 04 Feb 2024
Topic Review
Bush Dog
The Bush Dog (Speothos venaticus) emerges as a captivating and elusive canid species, residing in the dense and remote habitats of Central and South America. Recognized for its unique appearance and social behaviors, the Bush Dog stands out as a small yet highly specialized predator within the intricate tapestry of neotropical ecosystems. This elusive canid's cryptic lifestyle and distinctive pack dynamics make it a subject of intrigue for wildlife enthusiasts and researchers alike.
  • 443
  • 04 Feb 2024
Topic Review
Mass Spectrometry Investigation of ATP-Binding Cassette Proteins
Drug resistance remains one of the main causes of poor outcome in cancer therapy. It is also becoming evident that drug resistance to both chemotherapy and to antibiotics is driven by more than one mechanism. So far, there are at least eight recognized mechanisms behind such resistance. In normal tissues, ATP-binding cassette (ABC)  transporters protect the cells from the toxic effects of xenobiotics, whereas in tumor cells, they reduce the intracellular concentrations of anticancer drugs, which ultimately leads to the emergence of multidrug resistance (MDR). A deeper understanding of the structures and the biology of these proteins is central to current efforts to circumvent resistance to both chemotherapy, targeted therapy, and antibiotics. 
  • 107
  • 04 Feb 2024
Topic Review
The Supersymmetry Genetic Code table
The full set of relationship between 61 codons and 3 stop signals that specify the 20 naturals amino acids is called the genetic code. The fundamental role of symmetry in the genetic code is to decrease disorder (entropy) between codons and to preserve the integrity of system during evolution.
  • 275
  • 04 Feb 2024
Topic Review
Hoary Fox
The Hoary Fox (Lycalopex vetulus), a small canid species native to South America, captivates with its distinctive appearance and elusive nature. Characterized by a striking grizzled or hoary coat, this fox species navigates the savannas and grasslands of Brazil with an air of resilience and adaptability. Despite its enchanting presence, the Hoary Fox faces conservation challenges linked to habitat alteration and human-wildlife conflicts.
  • 253
  • 02 Feb 2024
Topic Review
Pantanal Cat
The Pantanal Cat, scientifically known as Leopardus colocola braccatus, is a captivating and elusive felid species native to the diverse ecosystems of the Pantanal region in South America. This small wild cat, a subspecies of the Colocolo, possesses a distinctive and visually striking coat pattern that aids in its camouflage within the lush landscapes of the Pantanal wetlands. The Pantanal Cat's mysterious nature and adaptation to its unique habitat make it an intriguing subject for study in the realm of wildlife biology and conservation.
  • 221
  • 02 Feb 2024
Topic Review
Northern Elephant Seal
The Northern Elephant Seal (Mirounga angustirostris) stands as a magnificent marine mammal, captivating researchers and nature enthusiasts alike. Known for its colossal size and distinctive, trunk-like proboscis, this species inhabits the eastern Pacific Ocean, predominantly along the coasts of California and Mexico. The life history of the Northern Elephant Seal is marked by remarkable adaptations for oceanic life, intricate social dynamics, and seasonal migrations, making it a compelling subject of study in marine biology.
  • 415
  • 02 Feb 2024
Topic Review
Metaverse Applications in Bioinformatics
Bioinformatics and genomics are driving a healthcare revolution, particularly in the domain of drug discovery for anticancer peptides (ACPs). The integration of artificial intelligence (AI) has transformed healthcare, enabling personalized and immersive patient care experiences. These advanced technologies, coupled with the power of bioinformatics and genomic data, facilitate groundbreaking developments. The precise prediction of ACPs from complex biological sequences remains an ongoing challenge in the genomic area. 
  • 207
  • 02 Feb 2024
Topic Review
Lysosomal-Cleavable Peptide Linkers in Antibody–Drug Conjugates
Antibody–drug Conjugates (ADCs) are a powerful therapeutic modality for cancer treatment. ADCs are multi-functional biologics in which a disease-targeting antibody is conjugated to an effector payload molecule via a linker. The success of currently used ADCs has been largely attributed to the development of linker systems, which allow for the targeted release of cytocidal payload drugs inside cancer cells.
  • 278
  • 02 Feb 2024
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