Topic Review
Heterosis
The phenomenon of heterosis has fascinated plant breeders ever since it was first described by Charles Darwin in 1876 in the vegetable kingdom and later elaborated by George H Shull and Edward M East in maize during 1908. Heterosis is the phenotypic and functional superiority manifested in the F1 crosses over the parents. Various classical complementation mechanisms gave way to the study of the underlying potential cellular and molecular mechanisms responsible for heterosis. In cereals, such as maize, heterosis has been exploited very well, with the development of many single-cross hybrids that revolutionized the yield and productivity enhancements.
  • 2.8K
  • 29 Oct 2020
Topic Review
Detection and Diagnosis of SARS-CoV-2/COVID-19
Latest weeks the humanity is faced with the spread of a new coronavirus, SARS-CoV-2 that causes a respiratory illness with high mortality rates, COVID-19. Since there is no approved treatment or vaccination against that specific coronavirus the reduce in virus spread is essential. That is based in the use of appropriate tools, enabling the accurate and early detection. Molecular biology and immunological techniques are widely used in order to predict the COVID-19 cases in a very short period of time. These are commonly based either in identification of the SARS-CoV-2’s genetic material or in detection of antibodies that have been produced by the immune system against the virus. Many of the above mentioned tests have been validated and approved by local authorities. However, there are much more companies that provide detection tests, without basic validation processes, contributing in non-precise data. The present review aim to analyze the most common platforms that are used in COVID-19 detection, analyzing their advantages and weaknesses. Therefore, each physician will be equipped with appropriate information required for each test.
  • 2.8K
  • 29 Oct 2020
Topic Review
List of Mammal Genera
There are currently 1258 genera, 156 families, 28 orders, and around 5937 recognized living species of mammal. Mammalian taxonomy is in constant flux as many new species are described and recategorized within their respective genera and families. The taxonomy represented here is a compilation of the most logical and up-to-date information on mammalian taxonomy from many sources, the main ones being the HMW series and the Mammals Species of the World by Wilson and Reeder.
  • 2.8K
  • 27 Oct 2022
Topic Review
Snijders Blok-Campeau Syndrome
Snijders Blok-Campeau syndrome is characterized by intellectual disability, speech problems, and distinctive facial features.  
  • 2.8K
  • 23 Dec 2020
Topic Review
Key Oil Palm Pests and Their Managements
Oil palm, Elaeis guineensis Jacq. (Arecales: Arecaceae), is a multipurpose plantation crop that is extensively grown in the humid tropics across Asia, Africa and the Americas for palm oil and other uses such as sauces, soap, wine, fertilizer (ashes), roofing (leaves), building material (trunk), medicines (roots), and ornamental purposes. Oil palm is attacked by numerous insect species globally, including defoliators, leaf/fruit scrapers, borers and sap feeders. The common oil palm pest management methods include synthetic insecticides, biopesticides, semiochemical lures, cultural practices, and integrated approaches.
  • 2.8K
  • 04 Jan 2023
Topic Review
Salamanders in Folklore
The salamander is an amphibian of the order Urodela which, as with many real creatures, often has been ascribed fantastic and sometimes occult qualities by pre-modern authors (as in the allegorical descriptions of animals in medieval bestiaries) not possessed by the real organism. The legendary salamander is often depicted as a typical salamander in shape with a lizard-like form, but is usually ascribed an affinity with fire, sometimes specifically elemental fire.
  • 2.8K
  • 17 Oct 2022
Topic Review
Classes of Transposable Elements
Transposable elements (TEs) are mobile genetic elements that constitute a sizeable portion of many eukaryotic genomes. Through their mobility, they represent a major source of genetic variation, and their activation can cause genetic instability and has been linked to aging, cancer and neurodegenerative diseases.
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  • 23 Sep 2022
Topic Review
Phosphoribosyl Pyrophosphate Synthetase
Phosphoribosyl pyrophosphate synthetase (PRS EC 2.7.6.1) is a rate-limiting enzyme that irreversibly catalyzes the formation of phosphoribosyl pyrophosphate (PRPP) from ribose-5-phosphate and adenosine triphosphate (ATP). This key metabolite is required for the synthesis of purine and pyrimidine nucleotides, the two aromatic amino acids histidine and tryptophan, the cofactors nicotinamide adenine dinucleotide (NAD+) and nicotinamide adenine dinucleotide phosphate (NADP+), all of which are essential for various life processes. Despite its ubiquity and essential nature across the plant and animal kingdoms, PRPP synthetase displays species-specific characteristics regarding the number of gene copies and architecture permitting interaction with other areas of cellular metabolism. The impact of mutated PRS genes in the model eukaryote Saccharomyces cerevisiae on cell signalling and metabolism may be relevant to the human neuropathies associated with PRPS mutations. Human PRPS1 and PRPS2 gene products are implicated in drug resistance associated with recurrent acute lymphoblastic leukaemia and progression of colorectal cancer and hepatocellular carcinoma.
  • 2.8K
  • 02 Aug 2022
Topic Review
Wearable Stretch Sensors
Wearable sensors are beneficial for continuous health monitoring, movement analysis, rehabilitation, evaluation of human performance. Wearable stretch sensors are increasingly being used for human movement monitoring. The content presented provides a review of wearable stretch sensors as well the design, development and validation of a wearable soft-robotic-stretch sensors. 
  • 2.8K
  • 25 Feb 2021
Topic Review
Epithelial–Mesenchymal Transition
Epithelial–mesenchymal transition (EMT) is a process that is crucial for embryogenesis, wound healing but also malignant progression. EMT leads to the changes in cell–cell and cell–ECM interactions, that allow the migration of epithelial cells and confer them to the mesenchymal phenotype
  • 2.8K
  • 06 Jan 2021
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