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Topic Review
Plant Sterols in Diabetes Management
The plant-based food we consume often contains many sterol-based bioactive compounds. It is well documented that these compounds could effectively manage the processes of insulin metabolism and cholesterol regulation. Insulin resistance followed by hyperglycemia often results in oxidative stress level enhancement and increased reactive oxygen species production. At the molecular level, these changes induce apoptosis in pancreatic cells and hence lead to insulin insufficiency. Studies have proved that plant sterols can lower inflammatory and oxidative stress damage connected with DNA repair mechanisms. The effective forms of phyto compounds are polyphenols, terpenoids, and thiols abundant in vegetables, fruits, nuts, and seeds. The available conventional drug-based therapies for the prevention and management of diabetes are time-consuming, costly, and with life-threatening side effects. Thereby, the therapeutic management of diabetes with plant sterols available in our daily diet is highly welcome as there are no side effects. 
  • 1.6K
  • 08 Dec 2021
Topic Review
Cardiac Extracellular Matrix
The extracellular matrix (ECM) is the non-cellular component in the cardiac microenvironment, and serves essential structural and regulatory roles in establishing and maintaining tissue architecture and cellular function. The patterns of molecular and biochemical ECM alterations in developing and adult hearts depend on the underlying injury type and epigenetic guidelines.
  • 1.6K
  • 19 Dec 2020
Topic Review
Therapeutic Monoclonal Antibodies
Therapeutic monoclonal antibodies (mAbs) target specifically antigens and have proven their efficacy in many human diseases, especially autoimmune diseases (rheumatoid arthritis, lupus, psoriasis, inflammatory bowel diseases), cancers (breast, lung, colorectal, and hematological cancers). Their humanization has greatly enhanced their biocompatibility and decreased their side effects such as immunogenicity. The clinical success of mAbs has expanded their application domain to other pathologies such as infectious, migraine, asthma, and hereditary diseases.
  • 1.6K
  • 18 Jan 2021
Topic Review
Lighting Strategy in Plant Factory with Artificial Light
A plant factory with artificial light (PFAL) is defined as an advanced agricultural production system with a precisely controlled environment, playing an important role in vertical farming and urban food supply. Artificial light is one of the core technologies in PFALs and accounts for a large part of energy consumption; elevating the light utilization efficiency of plants is vital for the sustainable development of PFALs. Meanwhile, the enclosed structure of the plant factory resulted in the independence of its light environment, indicating that the light environment in PFALs can be custom-made. Lighting strategy is an attempt to reprogram the light environmental parameters in unconventional ways, resulting in innovative lighting modes for energy-saving, high-yield, and high-quality production in PFALs. 
  • 1.6K
  • 30 May 2022
Topic Review
MALDI–TOF Mass Spectrometry in Microbiology
Mass spectrometry (MS) is an analytical technique that has emerged as a powerful tool in clinical microbiology for identifying peptides and proteins, which makes it a promising tool for microbial identification. Matrix assisted laser desorption ionization–time of flight MS (MALDI–TOF MS) offers a cost- and time-effective alternative to conventional methods, such as bacterial culture and even 16S rRNA gene sequencing, for identifying viruses, bacteria and fungi and detecting virulence factors and mechanisms of resistance. 
  • 1.6K
  • 24 Nov 2021
Topic Review
Embryonic Development
In developmental biology, embryonic development, also known as embryogenesis, is the development of an animal or plant embryo. Embryonic development starts with the fertilization of an egg cell (ovum) by a sperm cell, (spermatozoon). Once fertilized, the ovum becomes a single diploid cell known as a zygote. The zygote undergoes mitotic divisions with no significant growth (a process known as cleavage) and cellular differentiation, leading to development of a multicellular embryo after passing through an organizational checkpoint during mid-embryogenesis. In mammals, the term refers chiefly to the early stages of prenatal development, whereas the terms fetus and fetal development describe later stages.
  • 1.6K
  • 28 Apr 2023
Topic Review
Leaf Senescence
Leaf senescence is an ordered physiological process in which cellular structures and biomolecules are progressively broken down and the resulting products mobilized to other plant organs such as fruits, seeds, tubers and/or more apical leaves.
  • 1.6K
  • 02 Apr 2022
Topic Review
Wink
A wink is a facial expression made by briefly closing one eye. A wink is an informal mode of non-verbal communication usually signaling shared hidden knowledge or intent. However, it is ambiguous by itself and highly dependent upon additional context, without which a wink could become misinterpreted or even nonsensical. For example, in some regions of the world, a wink may be considered rude or offensive. And depending on the relationship of the people involved, a wink could possibly constitute a sexual gesture.
  • 1.6K
  • 07 Oct 2022
Topic Review
m6A Demethylases Inhibitors
N6-methyladenosine (m6A) is a post-transcriptional RNA modification and one of the most abundant types of RNA chemical modifications. m6A functions as a molecular switch and is involved in a range of biomedical aspects, including cardiovascular diseases, the central nervous system, and cancers.
  • 1.6K
  • 06 Jun 2022
Topic Review
Marine-Derived Phenolic Compounds
Phenolic metabolites are organic compounds with at least one or more hydroxyl groups attached to arylic systems with simple variations to highly polymerized molecules.
  • 1.6K
  • 10 Mar 2022
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