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Topic Review
Citrus Flavonoids Neohesperidin, Hesperidin and Its Aglycone, Hesperetin
Neohesperidin, hesperidin and hesperetin are citrus flavonoids from the flavanones subclass that have anti-inflammatory and antioxidant potential. Neohesperidin, in the form of neohesperidin dihydrochalcone (NHDC), also has dietary properties as a sweetener. 
  • 732
  • 23 May 2022
Topic Review
Photodynamic Therapy in Orthodontics
Treatment of malocclusions using fixed orthodontic appliances makes it difficult for patients to perform hygiene procedures. Insufficient removal of bacterial biofilm can cause enamel demineralization, manifesting by visible white spot lesions or periodontal diseases, such as gingivitis periodontitis or gingival hyperplasia. The classic methods of preventing the above problems include, in addition to proper hygiene, ultrasonic scaling, periodontal debridement, and oral rinses based on chlorhexidine. There is a growing interest among researchers in the possibility of using photodynamic therapy in orthodontics.
  • 729
  • 03 Jun 2021
Topic Review Peer Reviewed
Dental Patients’ Perspective on COVID-19: A Systematic Review
The COVID-19 epidemic has changed patients’ approach to dental treatments. While dentists worldwide have shown an excellent level of adaptability to face the new challenges presented by the unprecedented situation due to the rapid spread of COVID-19, dental patients have witnessed a sudden suspension of elective treatments and a slow resumption of dental care activities after several national lockdowns. In addition, the general climate of anxiety and fear due to the high COVID-19 risk and the high level of mortality has influenced the perception and attitudes of people towards dental activity, inducing many dental patients to avoid appointments to the dentist if not highly urgent. We present an overview of the current state of knowledge about dental patients’ perception, perspective, attitude, and expectations towards a full resumption of regular dental treatments.
  • 720
  • 27 Sep 2022
Topic Review
Anterior Open Bite Treatment with Skeletal Anchorage
Anterior open bite (AOB) is still one of the most difficult and demanding clinical problems. This malocclusion relies on a reduction in the vertical relationship between the incisal edges of the upper and lower incisors.
  • 715
  • 29 Dec 2021
Topic Review
Oral Lichen Planus
Oral lichen planus (OLP) is an autoimmune and chronic inflammatory disease. The etiology of OLP is still unknown, but it is believed to be associated with a cell-mediated immune dysregulation.
  • 712
  • 11 Jan 2021
Topic Review
3D Guided Insertion of Orthodontic Titanium Miniscrews
Orthodontic mini-implants (MIs), also called temporary anchorage devices (TADs), have been considered to be effective tools for intraoral anchorage reinforcement for many years. Their main advantages are their easy application, the possibility to use them at various stages of treatment and the predictability of biomechanical effects.
  • 711
  • 10 Dec 2021
Topic Review
Bioactive Glasses in Periodontal Regeneration
Bioactive glasses (BGs) were discovered by Larry L. Hench in 1969; the original composition, named Bioglass® 45S5 (45S5 from here on), displayed outstanding properties such as bone regeneration capabilities and antibacterial activity. In fact, such BG is an amorphous and biocompatible silica oxide-based inorganic material able to induce surface property responses resulting in the formation of a bond between the bone and the glass itself. In general, the surface of BGs, when soaked in physiological fluids, undergoes a complex ion exchange mechanism with the medium, inducing the formation of precipitates and subsequently hydroxyapatite deposition. This mechanism could explain the effectiveness of these BGs to bind to bones and the wide number of studies on BGs as supporting materials for bone tissue engineering and tooth remineralization.
  • 705
  • 01 Apr 2022
Topic Review
Growth Hormone Deficiency for Oral-Health
Growth hormone (GH) is involved in the regulation of the postnatal dental and skeletal growth, but its effects on oral health have not been clearly defined. This paper aims to provide a review of current clinical knowledge of dental caries, tooth wear, developmental enamel defects, craniofacial growth and morphology, dental maturation, and tooth eruption in growth hormone deficient (GHD) children. A systematic review was carried out using Scopus, MEDLINE-EbscoHost and Web of Science from 2000 to May 2021.
  • 704
  • 26 Aug 2021
Topic Review
Artificial Intelligence in the Diagnosis of Oral Diseases
Today, artificial intelligence (AI) has been suggested useful in disease diagnosis, predicting prognosis, or developing patient-specific treatment strategies. Particularly, AI can assist dentists in making time-sensitive critical decisions. It can remove the human element of error in decision-making, providing a superior and uniform quality of health care while reducing the stress load on the dentists.
  • 690
  • 13 May 2022
Topic Review
Dental Implants
Dental implants are widely used for oral prosthetic rehabilitation in case of partially (single or more missing teeth), as well as fully edentulous patients. It was demonstrated that osseointegrated implants have a high survival rate (cumulative mean of 94.6%, SD 5.97%) with a follow-up period of up to 20 years.
  • 683
  • 21 Aug 2021
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