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Topic Review
Hydrodynamics on Microbial Adhesion and Biofilm Formation
Studying microbial adhesion and biofilm growth is crucial for understanding the physiology of sessile organisms and forming the basis for the development of novel antimicrobial materials. Fluid hydrodynamics is one of the most important factors affecting cell adhesion, as well as biofilm structure and behavior. Therefore, to simulate the relevant biofilms of different fields (environment, industry, and medicine) in the laboratory, it is of utmost importance to select an adequate biofilm platform and be able to operate it at hydrodynamic conditions that are as close as possible to those encountered in a real scenario.
  • 1.5K
  • 21 Oct 2021
Topic Review
Bioactivities and Chemical Analysis of Ailanthus altissima(Mill.) Swingle
Many species of the so-called exotic plants coexist with native species in a balanced way, but others thrive very quickly and escape human control, becoming harmful—these are called invasive alien species. In addition to overcoming geographic barriers, these species can defeat biotic and abiotic barriers, maintaining stable populations. Ailanthus altissima is no exception; it is disseminated worldwide and is considered high risk due to its easy propagation and resistance to external environmental factors. Currently, it has no particular use other than ornamental, even though it is used to treat epilepsy, diarrhea, asthma, ophthalmic diseases, and seborrhoea in Chinese medicine. Considering its rich composition in alkaloids, terpenoids, sterols, and flavonoids, doubtlessly, its use in medicine or other fields can be maximised.
  • 1.5K
  • 17 Dec 2021
Topic Review
Role of Marine Macroalgae in Cosmeceuticals
The cosmetic industry uses the term ‘cosmeceutical’ to refer to a cosmetic formula that has drug-like applicative advantages. Many marine algae are rich in biologically active components that have been reported to exhibit strong benefits to the skin, mainly for photoprotection, skin whitening, moisturization, anti-aging, anti-wrinkle, antioxidants, and antimicrobial uses. 
  • 1.5K
  • 14 Mar 2022
Topic Review
Dyslipidemia in Renal Transplant Recipients
Dyslipidemia is a frequent complication after kidney transplantation (KT) and is an important risk factor for cardiovascular disease (CVD). Renal transplant recipients (RTRs) are considered at high, or very high, risk of CVD, which is a leading cause of death in patient group. Despite many factors of post-transplant dyslipidemia, the immunosuppressive treatment has the biggest influence on a lipid profile. There are no strict dyslipidemia treatment guidelines for RTRs, but the ones proposing an individual approach regarding CVD risk seem most suitable. Proper diet and physical activity are the main general measures to manage dyslipidemia and should be introduced initially in every patient after KT. In the case of an insufficient correction of lipemia, statins are the basis for hypolipidemic treatment. Statins should be introduced with caution to avoid serious side-effects (e.g., myopathy) or drug-drug interactions, especially with immunosuppressants. To lower the incidence of adverse effects, and improve medication adherence, ezetimibe in combination with statins is recommended. 
  • 1.5K
  • 31 May 2022
Topic Review
Magnetoencephalography (MEG) and Its Clinical Applications
MEG has two clinical applications, i.e., localization of epileptic foci and pre-operative evaluation for brain surgery candidates. MEG is also an important neuroimaging tool for the therapeutic planning of several mental disorders and abnormality analysis such as epilepsy, autism, schizophrenia, stroke, head trauma, and monitoring of drug administration
  • 1.5K
  • 27 Jun 2022
Topic Review
Agricultural Big Data Architectures and Climate Change
Climate change is currently one of agriculture’s main problems in achieving sustainability. It causes drought, increased rainfall, and increased diseases, causing a decrease in food production. In order to combat these problems, Agricultural Big Data contributes with tools that improve the understanding of complex, multivariate, and unpredictable agricultural ecosystems through the collection, storage, processing, and analysis of vast amounts of data from diverse heterogeneous sources.
  • 1.5K
  • 06 Jul 2022
Topic Review
J. M. E. McTaggart
John McTaggart Ellis McTaggart[lower-alpha 1] FBA (1866–1925) was an English idealist metaphysician. For most of his life McTaggart was a fellow and lecturer in philosophy at Trinity College, Cambridge. He was an exponent of the philosophy of Georg Wilhelm Friedrich Hegel and among the most notable of the British idealists. McTaggart is known for "The Unreality of Time" (1908), in which he argues that time is unreal. The work has been widely discussed through the 20th century and into the 21st.
  • 1.5K
  • 09 Oct 2022
Topic Review
World Religions
World religions is a category used in the study of religion to demarcate the five—and in some cases more—largest and most internationally widespread religious movements. Hinduism, Buddhism, Judaism, Christianity, and Islam are always included in the list, being known as the "Big Five". Some scholars also include other world religions, such as Taoism, Sikhism, Zoroastrianism, and/or the Baháʼí Faith, in the category. These are often juxtaposed against other categories, such as indigenous religions and new religious movements, which are also used by scholars in this field of research. The world religions paradigm was developed in the United Kingdom in the 1960s, where it was pioneered by phenomenological scholars like Ninian Smart. It was designed to broaden the study of religion away from its heavy focus on Christianity by taking into account other large religious traditions around the world. The paradigm is often used by lecturers instructing undergraduate students in the study of religion and is also the framework used by school teachers in the United Kingdom and other countries. The paradigm's emphasis on viewing these religious movements as distinct and mutually exclusive entities has also had a wider impact on the categorisation of religion—for instance in censuses—in both Western countries and elsewhere. Since the late 20th century, the paradigm has faced critique by scholars of religion like Jonathan Z. Smith, some of whom have argued for its abandonment. Critics have argued that the world religions paradigm is inappropriate because it takes the Protestant variant of Christianity as the model for what constitutes religion; that it is tied up with discourses of modernity, including modern power relations; that it encourages an uncritical understanding of religion; and that it makes a value judgement as to what religions should be considered "major". Others have argued that it remains useful in the classroom, so long as students are made aware that it is a socially-constructed category.
  • 1.5K
  • 18 Oct 2022
Topic Review
Pomeranian Language
The Pomeranian language (Polish: pomorszczyzna or język pomorski, German: Pomoranisch or die pomoranische Sprache) is in the Pomeranian group of Lechitic languages (Polish: grupa pomorska języków lechickich, German: die pomoranische Gruppe der lechischen Sprachen) within the West Slavic languages. In medieval contexts, it refers to the dialects spoken by the Slavic Pomeranians. In modern contexts, the term is sometimes used synonymously with "Kashubian" and may also include extinct Slovincian. The name Pomerania comes from Slavic po more, which means "[land] by the sea".
  • 1.5K
  • 20 Oct 2022
Topic Review
Bathymetric Chart
A bathymetric chart is a type of isarithmic map that depicts the submerged topography and physiographic features of ocean and sea bottoms. Their primary purpose is to provide detailed depth contours of ocean topography as well as provide the size, shape and distribution of underwater features. Topographic maps display elevation above ground and are complementary to bathymetric charts. Charts use a series of lines and points at equal intervals to showcase depth or elevation. A closed shape with increasingly smaller shapes inside of it can indicate an ocean trench or a seamount, or underwater mountain, depending on whether the depths increase or decrease going inward.Bathymetric surveys and charts are associated with the science of oceanography, particularly marine geology, and underwater engineering or other specialized purposes. thumb|Bathymetric Map of Medicine Lake, CABathymetric data used to produce charts can also be converted to bathymetric profiles which are vertical sections through a feature.thumb|right|Bathymetric chart of Bear Lake
  • 1.5K
  • 03 Nov 2022
Topic Review
Interval Scheduling
Interval scheduling is a class of problems in computer science, particularly in the area of algorithm design. The problems consider a set of tasks. Each task is represented by an interval describing the time in which it needs to be executed. For instance, task A might run from 2:00 to 5:00, task B might run from 4:00 to 10:00 and task C might run from 9:00 to 11:00. A subset of intervals is compatible if no two intervals overlap. For example, the subset {A,C} is compatible, as is the subset {B}; but neither {A,B} nor {B,C} are compatible subsets, because the corresponding intervals within each subset overlap. The interval scheduling maximization problem (ISMP) is to find a largest compatible set - a set of non-overlapping intervals of maximum size. The goal here is to execute as many tasks as possible. In an upgraded version of the problem, the intervals are partitioned into groups. A subset of intervals is compatible if no two intervals overlap, and moreover, no two intervals belong to the same group (i.e. the subset contains at most a single representative interval of each group). The group interval scheduling decision problem (GISDP) is to decide whether there exists a compatible set in which all groups are represented. The goal here is to execute a single representative task from each group. GISDPk is a restricted version of GISDP in which the number of intervals in each group is at most k. The group interval scheduling maximization problem (GISMP) is to find a largest compatible set - a set of non-overlapping representatives of maximum size. The goal here is to execute a representative task from as many groups as possible. GISMPk is a restricted version of GISMP in which the number of intervals in each group is at most k. This problem is often called JISPk, where J stands for Job. GISMP is the most general problem; the other two problems can be seen as special cases of it:
  • 1.5K
  • 07 Nov 2022
Biography
Melba Phillips
Melba Newell Phillips (February 1, 1907 – November 8, 2004) was an United States physicist and pioneer science educator. One of the first doctoral students of J. Robert Oppenheimer at the University of California, Berkeley, Phillips completed her Ph.D. in 1933, a time when few women pursued careers in science. In 1935 Oppenheimer and Phillips published[1] their description of the Oppenheimer-P
  • 1.5K
  • 16 Nov 2022
Topic Review
Soyuz TMA-20
Soyuz TMA-20 was a human spaceflight to the International Space Station (ISS) and was part of the Soyuz programme. It lifted off from the Baikonur Cosmodrome in Kazakhstan on December 15, 2010, and docked with the ISS two days later. The three-person crew of Soyuz TMA-20 – Dmitri Kondratyev, Catherine Coleman and Paolo Nespoli – represented the ISS partner organizations of Roscosmos, NASA and the European Space Agency (ESA). Soyuz TMA-20's crew represented half of the members of Expedition 27; the other three members of the expedition arrived at the station on board Soyuz TMA-21 on April 6, 2011. The COSPAR ID of Soyuz TMA-20 was 2010-067A. It is ISS flight 25S. On May 24, 2011, after spending 159 days in space, the Soyuz TMA-20 descent module landed safely in Zhezkazgan, Kazakhstan, carrying Kondratyev, Coleman and Nespoli.
  • 1.5K
  • 17 Nov 2022
Topic Review
Al-Abid
The Al-Abid(Arabic: العابد) LV was an Iraqi three-stage "Satellite launch system", a civilian project that was commenced in 1988. The Iraqis intended to launch an Al-Ta'ir satellite with the help of such a launch vehicle. The Iraqis therefore pursued a LV with stages based on Scud missiles and the S-75 Dvina. However only the first stage could be tested on December 1989 and according to General Ra'ad the next stages could not be developed. General Ra'ad says that not even the drawings of the second and third stage vehicles are available and that no final report could be produced. UN inspectors and U.S intelligence did not offer many details regarding the Al-Abid launch vehicle as they were not interested in it.
  • 1.5K
  • 29 Nov 2022
Topic Review
Gene Therapy for Patients with Hemophilia A
The standard of care for hemophilia A has been intravenous administration of exogenous factor VIII (FVIII), either as prophylaxis or episodically. Gene therapy is a treatment strategy used to repair or provide a functional copy of a gene that is either absent or expressed as a non-functional protein. Treating a genetic disease with gene therapy requires that the transgene (or its protein product) be delivered to the physiologically relevant target tissue or tissues, be stably expressed, and not interfere with the functional integrity of the cells in these tissues. The ultimate goal of gene therapy for patients with hemophilia A is the production of a treatment that is given as a one-time infusion and that allows adequate long-term expression of the deficient FVIII, with the maintenance of steady-state plasma FVIII concentrations. This would minimize (or ideally eliminate) bleeding episodes and thereby decrease the patient and societal burden of the disease.
  • 1.5K
  • 29 Nov 2022
Topic Review
Contaminant Cocktails of High Concern in Honey
Environmental pollution is a crucial problem in our society, having a better understanding of its consequences, which include the increase of contaminant cocktails present in the environment. The contamination of honeybees can occur through their interaction with the nearby environment. Therefore, if honeybees are previously contaminated, there is a possibility of contamination of their products, such as honey as natural, or minimally processed, product, resulting from the honeybees’ activity.
  • 1.5K
  • 14 Apr 2023
Topic Review
Vibrotactile Feedback in Virtual Reality
While substantial progress in computer graphics and sound rendering has resulted in highly realistic visual and auditory experiences in virtual reality (VR), achieving genuine immersion, interactivity, and the stimulation of imagination necessitates the integration of realistic tactile experiences, often facilitated through haptic feedback. The incorporation of vibrotactile feedback in VR allows users to fully engage their sense of touch, enabling them to explore, grasp, and manipulate virtual objects as if they were interacting with them in the physical world.
  • 1.5K
  • 22 Jan 2024
Topic Review
Guideline for the Decommissioning/Abandonment of Subsea Pipelines
The operating lifespan of pipelines is limited, defined by their specific design codes and specifications, with the economic justification for this being determined primarily by the pipeline owner. During its operational lifespan, a pipeline’s integrity is affected mainly by the quality of the hydrocarbons being transported. The integrity of a pipeline can be maintained with regular inspections and maintenance/cleaning programmes followed from installation to commissioning. As production matures and declines, operators face several decisions concerning the pipeline’s future. There are several potential scenarios, and each should be assessed on a case-by-case basis for any specific pipeline in question. The industry best practices outline the minimum requirements for the safe decommissioning of pipelines. 
  • 1.5K
  • 20 Feb 2024
Topic Review
Heteromeric TRP Channels
Heteromeric Transient Receptor Potential (TRP) channels build a tetrameric structure with at least one TRP subunit from another subfamily. In pulmonary microvascular endothelial cells their activation can disrupt endothelial barrier function, as their mediated calcium influx activates the CaM (calmodulin)/MLCK (myosin light chain kinase)-signaling pathway, and thereby rearranges the cytoskeleton, increases endothelial permeability and thus can facilitate activation of inflammatory cells and formation of pulmonary edema.
  • 1.5K
  • 06 Jul 2021
Topic Review
Female Fertility and Environmental Pollution
Terrestrial ecosystems are contaminated by heavy metals and organic chemicals that can be taken up by and accumulate in crop plants, and water tables are heavily contaminated by untreated industrial discharges. As deadly particulates can drift far, poor air quality has become a significant global problem and one that is not exclusive to major industrialized cities. The consequences are a dramatic impairment of our ecosystem and biodiversity and increases in degenerative or man-made diseases. In this respect, it has been demonstrated that environmental pollution impairs fertility in all mammalian species. The worst consequences are observed for females since the number of germ cells present in the ovary is fixed during fetal life, and the cells are not renewable. This means that any pollutant affecting hormonal homeostasis and/or the reproductive apparatus inevitably harms reproductive performance. 
  • 1.5K
  • 18 Jan 2021
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