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Topic Review
GIS and BIM and HBIM Integration
3D virtual management is a topic of growing interest. The AEC industry is undergoing a real revolution because of the technological changes that are taking place. Synchronized 3D visualization is one of the tools being deployed at an accelerated pace. This, together with collaborative work, contributes to optimal management for all stakeholders. The integration of geographic information systems and building information modeling and heritage building information modeling (BIM) is one of the most innovative concepts; it enables the generation of collaborative, fluid systems. 
  • 1.4K
  • 09 Nov 2022
Topic Review
Cromemco Dazzler
Cromemco's Dazzler (or TV DAZZLER) is a graphics card for S-100 bus computers. Released in 1976, it is the first commercial color bit-mapped graphics card available for microcomputers. Multiple Dazzler cards could be installed in a single machine and synced together, a feature which could, with minor modification, be used to genlock. Genlocked Dazzler cards drove ColorGraphics Weather Systems displays that generated most of the weather imagery seen on US television in the early 1980s.
  • 1.4K
  • 11 Nov 2022
Topic Review
Coastal Acid-Sulfate Soils of Kalimantan, Indonesia
Coastal acid-sulfate soils are crucial for producing crops and thus, for food security. However, over time, these soil resources experience degradation, leading to higher agro-input, lower yields, and environmental hazards that finally threaten food security. The optimal use of this fragile resource is only attained by implementing vigorous integrated water–soil–crop management technologies amid the climate change impact. 
  • 1.4K
  • 27 Mar 2024
Topic Review
The Assembly of PPTA Nanofibers and the Applications
Poly (p-phenylene terephthalamide) (PPTA) is one kind of lyotropic liquid crystal polymer. Kevlar fibers made from PPTA is widely used in many fields due to the superior mechanical properties resulted from highly oriented macromolecular structure. However, the “infusible and insoluble” characteristic of PPTA gives rise to its poor processability, which limits its scope of application. The strong interactions and orientation characteristic of aromatic amide segments make PPTA attractive in the field of self-assembly. The chemical derivations have proved an effective way to modify the molecular structure of PPTA to improve its solubility and amphiphilicity, which resulted in different liquid crystal behaviors or supramolecular aggregates, but the modification of PPTA is usually complex and difficult. Alternatively, higher order all-PPTA structures have also been realized through the controllable hierarchical self-assembly of PPTA from the polymerization process to the formation of macroscopic products. It briefly introduces the self-assembly methods of PPTA based materials in recent years, and focuses on the polymerization-induced PPTA nanofibers which can be further fabricated into different macroscopic architectures when other self-assembly methods are combined. This monomer-started hierarchical self-assembly strategy evokes the feasible processing of PPTA, and enriches the diversity of product, which is expected to be expanded to other liquid crystal polymers.
  • 1.4K
  • 20 Jul 2022
Topic Review
Birkhoff's Representation Theorem
In mathematics, Birkhoff's representation theorem for distributive lattices states that the elements of any finite distributive lattice can be represented as finite sets, in such a way that the lattice operations correspond to unions and intersections of sets. The theorem can be interpreted as providing a one-to-one correspondence between distributive lattices and partial orders, between quasi-ordinal knowledge spaces and preorders, or between finite topological spaces and preorders. It is named after Garrett Birkhoff, who published a proof of it in 1937. The name “Birkhoff's representation theorem” has also been applied to two other results of Birkhoff, one from 1935 on the representation of Boolean algebras as families of sets closed under union, intersection, and complement (so-called fields of sets, closely related to the rings of sets used by Birkhoff to represent distributive lattices), and Birkhoff's HSP theorem representing algebras as products of irreducible algebras. Birkhoff's representation theorem has also been called the fundamental theorem for finite distributive lattices.
  • 1.4K
  • 10 Oct 2022
Topic Review
Eclipse Public License
The Eclipse Public License (EPL) is a free and open source software license most notably used for the Eclipse IDE and other projects by the Eclipse Foundation. It replaces the Common Public License (CPL) and removes certain terms relating to litigations related to patents. The Eclipse Public License is designed to be a business-friendly free software license, and features weaker copyleft provisions than licenses such as the GNU General Public License (GPL). The receiver of EPL-licensed programs can use, modify, copy and distribute the work and modified versions, in some cases being obligated to release their own changes. The EPL is listed as a free software license by the Free Software Foundation (FSF) and approved by the Open Source Initiative (OSI). Discussion of a new version of the EPL began in May 2013. Version 2.0 was announced on 24 August 2017. On January 20, 2021, the license steward for the license was changed from Eclipse.org Foundation, Inc. (Delaware, USA) to Eclipse Foundation AISBL (Brussels, Belgium).
  • 1.4K
  • 21 Nov 2022
Topic Review
Challenges in Recycling of Multi-Material Composites
Transformation of waste into resources is an important part of the circular economy. The recovery of materials in the most effective way is crucial for sustainable development. Composite materials offer great opportunities for product development and high performance in use, but their position in a circular economy system remains challenging, especially in terms of material recovery.
  • 1.4K
  • 17 Oct 2023
Topic Review
Antibacterial Activity and Applications of Eugenol-Based Polymeric Materials
Eugenol (4-Allyl-2-methoxy phenol) (EUG) is a plant-derived allyl chain-substituted guaiacol, widely known for its antimicrobial and anesthetic properties, as well as the ability to scavenge reactive oxygen species. It is typically used as a mixture with zinc oxide (ZOE) for the preparation of restorative tooth fillings and treatment of root canal infections.
  • 1.4K
  • 08 Nov 2023
Topic Review
Nutrition-focused QIPs in Cancer Care
Malnutrition in patients with cancer is a ubiquitous but neglected problem that can reduce patient survival/quality of life and increase treatment interruptions, readmission rates, and healthcare costs. Malnutrition interventions, including nutrition support through dietary counseling, diet fortification, oral nutrition supplements (ONS), and enteral and parenteral nutrition can help improve health outcomes. However, nutritional care standards and interventions for cancer are ambiguous and inconsistently applied. The lack of systematic malnutrition screening and intervention in ambulatory cancer care has especially significant consequences and thus the nutrition support of patients with cancer represents an area for quality improvement. United States healthcare payment models such as the Oncology Care Model are linked to quality of care and health outcomes. Quality improvement programs (QIPs) can advance patient-centered care, perfect care processes, and help healthcare professionals meet their quality measure performance goals. Malnutrition QIPs like the Malnutrition Quality Improvement Initiative (MQii) have been shown to be effective in identifying and treating malnutrition. However, little is known about or has been reported on nutrition or malnutrition-focused QIPs in cancer care. This paper provides information to support translational research on quality improvement and outlines the gaps and potential opportunities for QIPs in the nutrition support of patients with cancer.
  • 1.4K
  • 27 Oct 2020
Topic Review Peer Reviewed
Brainstem fMRI
The human brainstem plays important roles in maintaining basic vital functions. In comparison with brain functional magnetic resonance imaging (fMRI), only a few fMRI studies investigating the brainstem have been reported because of a number of technical challenges. This entry briefly introduces technical difficulties, recent advances, and further directions of brainstem fMRI in humans. 
  • 1.4K
  • 13 Apr 2022
Topic Review
A2B Adenosine Receptors
Adenosine is a signalling molecule which, by activating specific membrane receptors, acts as an important player during brain insults such as ischemia. or demyelinating injuries. Here we review data in the literature describing A2B receptor-mediated effects in preclinical in vitro and in vivo models of cerebral ischemia and myelination that point to A2B receptor ligands as putative therapeutic targets for the still unmet treatment of stroke or demyelinating diseases.
  • 1.4K
  • 14 Apr 2021
Topic Review
Endolysosomal TRPMLs
Lysosomes, the membrane-bound digestive cell organelles, are well-known for their catabolic function.
  • 1.4K
  • 04 Feb 2021
Topic Review
Polysaccharide-Based Materials
Polysaccharide-based materials created by physical processes have received considerable attention for biomedical applications. 
  • 1.4K
  • 20 May 2021
Topic Review
LGR4
Leucine-rich repeats containing G protein-coupled receptor 4 (LGR4) is a receptor that belongs to the superfamily of G protein-coupled receptors that can be activated by R-spondins (RSPOs), Norrin, circLGR4, and the ligand of the receptor activator of nuclear factor kappa-B (RANKL) ligands to regulate signaling pathways in normal and pathological processes.
  • 1.4K
  • 21 May 2021
Topic Review
Tumor Microenvironment and Oncolytic Virotherapy
The Tumor Microenvironment (TME) represents an important barrier that can hinder immune responses against tumors and also attenuate immunotherapeutic efficacy.
  • 1.4K
  • 04 Aug 2021
Topic Review
NLRP3
The NLRP3 inflammasome (NOD-, LRR-, and pyrin domain-containing protein 3) is an intracellular, multiprotein signalling complex implicated in a plethora of inflammatory diseases. These integral elements include the sensor NLRP3 protein, an adaptor protein called adaptor molecule apoptosis-associated speck-like protein containing a CARD (ASC) and procaspase-1. The sensor NLRP3 protein can be triggered by PAMPs, DAMPs, and a range of diverse external stimuli such as infection and injury.
  • 1.4K
  • 03 Nov 2021
Topic Review
Autonomous Molecular Design: Machine Intelligence
The workflow for computational autonomous molecular design (CAMD) must be an integrated and closed-loop system with (i) efficient data generation and extraction tools, (ii) robust data representation techniques, (iii) physics-informed predictive machine learning (ML) models, and (iv) tools to generate new molecules using the knowledge learned from steps i–iii.
  • 1.4K
  • 29 Mar 2022
Topic Review
G Protein Coupled Receptor 158
G-protein-coupled receptors (GPCRs) remain one of the most successful targets for therapeutic drugs approved by the US Food and Drug Administration (FDA). Many novel orphan GPCRs have been identified by human genome sequencing and considered as putative targets for refractory diseases. Of note, a series of studies have been carried out involving GPCR 158 (or GPR158) since its identification in 2005, predominantly focusing on the characterization of its roles in the progression of cancer and mental illness. However, advances towards an in-depth understanding of the biological mechanism(s) involved for clinical application of GPR158 are lacking.
  • 1.4K
  • 28 Apr 2022
Topic Review
Impact of Leaders’ Coaching Skills on Employees
The relationship between employees and leaders is fundamental in creating effective people and successful companies by guiding the individual towards understanding the differences and similarities they have with the organization and enabling leaders to provide employee development. Leaders with coaching skills build a safe working environment that employees can trust and improve work performance, develop employee self-awareness, and increase their satisfaction with their work, leader, and company. A leader coach not only shares their knowledge but also recognizes effort, advises, and provides attentive feedback. This leadership style is seen as an organizational tool to motivate, promote, and satisfy innovative behaviors in workers.
  • 1.4K
  • 10 Aug 2022
Topic Review
Kounotori 3
Kounotori 3 (Japanese: こうのとり3号機; English: "white stork" ), also known as HTV-3, is the third Japan ese H-II Transfer Vehicle. It was launched on 21 July 2012 to resupply the International Space Station (ISS) aboard the H-IIB Launch Vehicle No. 3 (H-IIB F3) manufactured by Mitsubishi Heavy Industries (MHI) and JAXA. Kounotori 3 arrived at the ISS on 27 July 2012, and Expedition 32 Flight Engineer and JAXA astronaut Akihiko Hoshide used the International Space Station's Canadarm2 robotic arm to install Kounotori 3, to its docking port on the Earth-facing side (nadir) of the Harmony module at 14:34 UTC. After the supplies are unloaded, Kounotori 3 was loaded with waste material from ISS, including used experiment equipment and used clothes. Then Kounotori 3 was unberthed from the ISS on 11 September 2012 and burned up upon reentering in the atmosphere of Earth on 14 September 2012.
  • 1.4K
  • 21 Oct 2022
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