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Topic Review
Animal Personality
Animal personality can be defined as behavioral and physiological differences between individuals of the same species, which are stable in time and across different contexts.
  • 1.5K
  • 09 Apr 2021
Topic Review
Hypereosinophilia and Hypereosinophilic Syndromes
Hypereosinophilia (HE) is a heterogeneous condition with a persistent elevated eosinophil count of >350/mm3, which is reported in various (inflammatory, allergic, infectious, or neoplastic) diseases with distinct pathophysiological pathways. HE may be associated with tissue or organ damage and, in this case, the disorder is classified as hypereosinophilic syndrome (HES).
  • 1.5K
  • 15 Jun 2021
Topic Review
Wastewater Treatment Processes
Wastewater generated from various industrial sectors contains micropollutants, nutrients (nitrogen, sulfur, copper, phosphorus), carbon-based pollutants (antibiotics, aromatic hydrocarbons, biocides, phenolic compounds, and surfactants etc.) and heavy metals (cadmium, chromium, copper, mercury nickel, lead, and zinc) . 
  • 1.5K
  • 19 May 2021
Topic Review
Telomerase in Age-Related Macular Degeneration
Age-related macular degeneration (AMD), the main cause of vision loss in the elderly, is associated with oxidation in the retina cells promoting telomere attrition. Activation of telomerase was reported to improve macular functions in AMD patients. The catalytic subunit of human telomerase (hTERT) may directly interact with proteins important for senescence, DNA damage response, and autophagy, which are impaired in AMD. hTERT interaction with mTORC1 (mTOR (mechanistic target of rapamycin) complex 1) and PINK1 (PTEN-induced kinase 1) activates macroautophagy and mitophagy, respectively, and removes cellular debris accumulated over AMD progression. Ectopic expression of telomerase in retinal pigment epithelium (RPE) cells lengthened telomeres, reduced senescence, and extended their lifespan. 
  • 1.5K
  • 09 Jul 2021
Topic Review
Mobile Communications for Tourism&Hospitality
As the fifth-generation (5G) mobile communication technology captures public attention, reviewing the first to fourth generations with the anticipated implications of 5G and afterward, and future research would present a useful value to the literature. This study uses a systematic content analysis methodology to provide a comprehensive and interdisciplinary review of mobile communication research in tourism and hospitality to help academic researchers and industry practitioners understand the research area. The study also analyzes the future changes that mobile communication technologies and their applications will bring to tourism and hospitality research trends and industry practices. 
  • 1.5K
  • 06 Aug 2021
Topic Review
Corporate Governance
A good corporate governance relies on the existence of some trust relationships between the entity, the investors, and other interested parties.
  • 1.5K
  • 26 Jun 2022
Topic Review
Excipients to Inhibit Efflux Transporters
Efflux transporters distributed at the apical side of human intestinal epithelial cells actively transport drugs from the enterocytes to the intestinal lumen, which could lead to extremely poor absorption of drugs by oral administration. Efflux transporters in the gastrointestinal tract mainly include P-gp, MRPs and BCRP.
  • 1.5K
  • 17 Jun 2022
Topic Review
Applications of High Molecular Weight Poly(Methyl Methacrylate)
Poly(methyl methacrylate) (PMMA), commonly known as plexiglass, is a kind of polymer synthesized by free radical polymerization, ionic polymerization and coordination polymerization. Poly(methyl methacrylate) (PMMA) is widely used in aviation, architecture, medical treatment, optical instruments and other fields because of its good transparency, chemical stability and electrical insulation.
  • 1.5K
  • 12 Jul 2022
Topic Review
Active Evidence-Based Learning in Engineering Education
Implementing active learning methods in engineering education is becoming the new norm and is seen as a prerequisite to prepare future engineers not only for their professional life, but also to tackle global issues. Teachers at higher education institutions are expected and encouraged to introduce their students to active learning experiences, such as problem-, project-, and more recently, challenge-based learning. 
  • 1.5K
  • 09 Nov 2022
Topic Review
Pluripotent Stem Cells in Livestock and Wildlife
Induced pluripotent stem cell (iPSC) technology is an emerging technique to reprogram somatic cells into iPSCs that have revolutionary benefits in the fields of drug discovery, cellular therapy, and personalized medicine. In both mice and humans, embryonic stem cell lines (ESCs) have been established. However, this is not the case for farm and wild animals. Cryopreservation is an important and useful approach to preserve endangered wild and domestic species as well as their genetic material. Several studies have shown the potential of iPSCs to prevent the extinction of several valuable species, such as the snow leopard, Bengal tiger, drill monkey, and white rhinoceros
  • 1.5K
  • 22 Nov 2022
Topic Review
Information Technology (Intermediary Guidelines (Amendment) Rules) 2018
The draft Information Technology [Intermediary Guidelines (Amendment) Rules] 2018 seeks to amend India 's Intermediary Guidelines Rules 2011 by making intermediaries legally required to provide time-bound assistance to any government agency, provide traceability requirements, as well as deploy "technology-based automated tools to identify and remove public access to unlawful information". Intermediaries with more than 5,000,000 users must set up a company in India. The changes also include prohibited hosting of another category of content, i.e. ‘public health or safety’. The draft Rules have been framed under Section 79 of the Information Technology Act, 2000 which covers intermediary liability. The Indian Government’s Ministry of Electronics and Information Technology (MeitY) had invited comments on proposed amendments early in 2019. The amendments were seen by many to "overstep the aforesaid intention sparking concerns of violating free speech and privacy rights of individuals." It is seen that "the guidelines suffer with excessive delegation of powers and shift the burden of responsibility of identification of unlawful content from a government/ judiciary to intermediaries." A total of 171 comments were received by MeitY; all of the comments were published for counter comments. On 21 October 2019, MeitY asked the court for three months’ time for finalisation of the Intermediary Rules, 2018.
  • 1.5K
  • 06 Dec 2022
Topic Review
Surgical Anatomy of the Upper Abdomen
Cytoreductive surgery (CRS) is the cornerstone of treating advanced ovarian cancer. Approximately 60–70% of patients with advanced ovarian cancer will have involvement in the upper abdomen or the supracolic compartment of the abdominal cavity. Though the involvement of this region results in poorer survival compared, complete cytoreduction benefits overall survival, making upper-abdominal cytoreduction an essential component of CRS for advanced ovarian cancer. The upper abdomen constitutes several vital organs and large blood vessels draped with the parietal or visceral peritoneum, common sites of disease in ovarian cancer. A surgeon treating advanced ovarian cancer should be well versed in upper-abdominal cytoreduction techniques, including diaphragmatic peritonectomy and diaphragm resection, lesser omentectomy, splenectomy with or without distal pancreatectomy, liver resection, cholecystectomy, and suprarenal retroperitoneal lymphadenectomy. Other procedures such as clearance of the periportal region, Glisson’s capsulectomy, clearance of the superior recess of the lesser sac, and Morrison’s pouch are essential as these regions are often involved in ovarian cancer. 
  • 1.5K
  • 03 Jan 2023
Topic Review
Transport Infrastructure Construction History in the United Kingdom
The performance of geostructures in the United Kingdom (UK)’s transport network is significantly impacted by their construction age. A considerable portion of railway geostructures were constructed in the late 19th and early 20th century. 
  • 1.5K
  • 11 Aug 2022
Topic Review
Diagnosis and Treatment in Allergic Rhinitis
Respiratory diseases are pathological conditions that affect airways, hampering breathing and causing high mortality. In particular, asthma and allergic rhinitis (AR) are two of the most common airway diseases that affect millions of people and have a high prevalence in childhood and adulthood. Asthma is a heterogeneous chronic inflammatory disease characterized by wheezing, chest tightness, shortness of breath, and cough. AR occurs with rhinorrhea, nasal congestion, and sneezing. Indeed, these pathologies share common physiopathological mechanisms such as airway hyperresponsiveness and similar immunopathology such as tissue eosinophilia and T-helper type 2 inflammation. Moreover, AR can be an important risk factor for suffering asthma.
  • 1.5K
  • 08 Feb 2023
Topic Review
Neuropsychological Outcomes of Children Treated for Brain Tumors
Central nervous system (CNS) neoplasms are the most common solid tumors diagnosed in children. CNS tumors represent the leading cause of cancer death and cancer-related morbidity for children less than 20 years of age. Neurological, cognitive, and neuropsychological deficits are the most disabling long-term effects of brain tumors in children. Childhood is a time of extreme brain sensitivity and the time of life in which most brain development occurs. Thus, the long-term toxicities that children treated for CNS tumors experience can affect multiple developmental domains and day-to-day functioning, ultimately leading to a poor quality of survival (QoS). 
  • 1.5K
  • 08 Mar 2023
Topic Review
Health Implications of Oxalates
Oxalate is an antinutrient present in a wide range of foods, with plant products, especially green leafy vegetables, being the main sources of dietary oxalates. This compound has been largely associated with hyperoxaluria, kidney stone formation, and, in more severe cases, systematic oxalosis. Due to its impact on human health, it is extremely important to control the amount of oxalate present in foods, particularly for patients with kidney stone issues.
  • 1.5K
  • 31 Aug 2023
Topic Review
Time Domain CMOS Temperature Sensor
Temperature sensors is based on the sensory device (CMOS, BJT or resistor) and the measured signal type (voltage, current, frequency, delay time, phase shift or bandwidth), they can be implemented in various ways. By defining the temperature estimation function X(T) as the ratio of two quantities chosen from tREF, t(T), fREF and f(T), a time domain temperature sensor can be implemented based on one among 12 types of operational principles.
  • 1.5K
  • 30 Oct 2020
Topic Review
Forest Therapy in China
Forest therapy has emerged as a preventive and alternative therapy to cope with stress and enhance people’s health and wellbeing as a result of spending time in a green and healthy environment. Forest therapy activities in China include Forest health and wellness, forest healthcare, forest tourism, forest experiences, and forest wellness. 
  • 1.5K
  • 07 Jun 2021
Topic Review
Ejaculatory Abstinence Interval
A shorter than routinely recommended at present (up to seven days based on the WHO Manual) ejaculatory abstinence interval may result in improved sperm parameters, such as sperm DNA fragmentation, progressive motility or morphology with a potential clinical benefit in IVF/ICSI cycles. In this regard, patients should be discouraged from abstaining for a prolonged time due to the potential negative impact on both semen parameters and clinical outcomes. Further studies to better define the optimum abstinence interval within the SAP are urgently warranted.
  • 1.5K
  • 25 Nov 2021
Topic Review
Periosteum-Derived Mesenchymal Stromal Cells
The periosteum, with its outer fibrous and inner cambium layer, lies in a dynamic environment with a niche of pluripotent stem cells for their reparative needs. The inner cambium layer is rich in mesenchymal progenitors, osteogenic progenitors, osteoblasts, and fibroblasts in a scant collagen matrix environment. Their role in union and remodeling of fracture is well known.  From a therapeutic standpoint, the periosteum as a source of tissue engineering has gained much attraction. 
  • 1.5K
  • 13 Dec 2021
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