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Topic Review
Modelling of Loss Given Default of Bank Loans
The loss given default (LGD) is the ratio of the amount of loss to a lender resulting from a borrower’s default to risk exposure. LGD is an important credit risk parameter in the regulatory system for financial institutions.
  • 1.5K
  • 25 Oct 2023
Topic Review
Quetiapine-Related Deaths
Quetiapine is a second-generation antipsychotic drug available for two and half decades. Due to increased misuse, prescription outside the approved indications, and availability on the black market, it is being encountered in medicolegal autopsies more frequently. For instance, it has been linked to increased mortality rates, most likely due to its adverse effects on the cardiovascular system. 
  • 1.5K
  • 10 Jan 2024
Topic Review
Insulin Growth-Factor-Binding Protein 2
Evidence from observational and in vitro studies suggests that insulin growth-factor-binding pro-tein type 2 (IGFBP2) is a promising protein in non-communicable diseases, such as obesity, insulin resistance, metabolic syndrome, or type 2 diabetes. Accordingly, great efforts have been carried out to explore the role of IGFBP2 in obesity state and insulin-related diseases, which it is typically found decreased.
  • 1.5K
  • 28 Jan 2021
Topic Review
Adipose Tissue Mitochondria
Mitochondria play a key role in maintaining energy homeostasis in metabolic tissues, including adipose tissues. The two main types of adipose tissues are the white adipose tissue (WAT) and the brown adipose tissue (BAT). WAT primarily stores excess energy, whereas BAT is predominantly responsible for energy expenditure by non-shivering thermogenesis through the mitochondria. WAT in response to appropriate stimuli such as cold exposure and β-adrenergic agonist undergoes browning wherein it acts as BAT, which is characterized by the presence of a higher number of mitochondria. 
  • 1.5K
  • 10 Nov 2021
Topic Review
Coriander Plants and Human Emotions
Coriander or Coriandrum sativum (C. sativum), a member of the Apiaceae family, is a popular herb with versatile applications. The seeds and leaves are widely used for culinary and seasoning. The seeds and fruits are often used for cooking meat. As honey plant, coriander is highly attractive to honeybee workers. Additionally, coriander has been used in many traditional medicines, and its medicinal values has been widely recognized. Coriander extracts have a wide range of biological benefits including neuroprotective, anxiolytic, hypnotic, antioxidant, anti-inflammatory, and so on.
  • 1.5K
  • 19 Apr 2022
Topic Review
Bioactive Glasses in Bone Regeneration
Mesoporous bioactive glasses (MBGs) is a category of bioceramics that, as will be explained, can be considered intermediate between traditional bioactive glasses—obtained by quenching of a melt or by the sol-gel method—and silica mesoporous materials. These bioactive glasses can be considered a spin-off of silica mesoporous materials because they are designed with a similar technical approach. Mesoporous glasses in addition to SiO2 contain significant amounts of other oxides, particularly CaO and P2O5 and therefore, they exhibit quite different properties and clinical applications than mesoporous silica compounds. Both materials exhibit ordered mesoporous structures with a very narrow pore size distribution that are achieved by using surfactants during their synthesis. The characteristics of mesoporous glasses made them suitable to be enriched with various osteogenic agents, namely inorganic ions and biopeptides as well as mesenchymal cells. 
  • 1.5K
  • 19 Apr 2022
Topic Review
Organization of Indian Steel Sector
Steel manufacturing is a technologically complex industry having subsequent linkages in terms of material flow and plays a vital role in determining infrastructure and the overall development of a country. The global steel industry and its supply chain constitute 40 million jobs across the world. In 2019, India established itself as the second-largest steel producer with 111.3 million tons, constituting 5.9% of total crude steel production on the planet for the respective year, and it has ambitious plans to produce 250 million tons by 2030 with a per capita consumption aim of 160 kg.
  • 1.5K
  • 20 Apr 2022
Topic Review
Experimental Animal Skin Flap Models
Skin flaps are necessary in plastic and reconstructive surgery for the removal of skin cancer, wounds, and ulcers. A skin flap is a portion of skin with its own blood supply that is partially separated from its original position and moved from one place to another. The use of skin flaps is often accompanied by cell necrosis or apoptosis due to ischemia–reperfusion (I/R) injury.
  • 1.5K
  • 20 May 2022
Topic Review
Immunotherapeutic Approaches for Angioimmunoblastic T-cell Lymphoma
Escaping the immune system is the main characteristic of a tumor cell. In order to limit the anarchic proliferation of cancer cells, chemotherapies are often used in tumors that have no specific treatment yet, such as AITL. These therapies are proposed to limit the proliferation of dividing cells, i.e., healthy cells as well as tumor cells. This explains the poor benefits of such treatment and the major risk of relapse or even the absence of signs of remission. Importantly, targeting a specific cancer cell type without inducing an effect on healthy cells requires an in-depth knowledge of its phenotype and its surface markers, which can serve as an asset for the development of specific therapies, in particular immunotherapies. If some healthy cells are affected, it is called on-target off-target effects because certain cancer epitopes are partially expressed on non-malignant cells. These therapies include, for example, monoclonal antibodies and chimeric antigen receptors. 
  • 1.5K
  • 25 May 2022
Topic Review
Marine Collagen in Pharmacological, Biomedical, and Regenerative Medicine
Several bioactive compounds of marine origin are being studied, and among these, marine collagen represents one of the most attractive bio-resources, given its use in various disciplines, such as clinical applications, cosmetics, the food sector, and many other industrial applications. The applications of Marine collagen in pharmacological, biomedical fields and regenerative medicine are discussed. 
  • 1.5K
  • 28 Feb 2023
Topic Review
Materials for 3D Bioprinting
Three-dimensional (3D) bioprinting has emerged as a promising scaffold fabrication strategy for tissue engineering with excellent control over scaffold geometry and microstructure. Nanobiomaterials as bioinks play a key role in manipulating the cellular microenvironment to alter its growth and development.
  • 1.5K
  • 12 Apr 2023
Topic Review
Two phytochrome A Types in Plants
The phytochrome (phy) system of plants with the main phyA and phyB controls their development beginning from seed germination to fruiting and senescence. The regulation reactions are categorized into three modes—the very low and low fluence responses (VLFR and LFR) and the high irradiance responses (HIR). The phyA is unique among the other phytochromes; it is major in etiolated seedlings and light-labile, and mediates all the three photoresponse modes. The phyB is light-stable, dominates in deetiolated plants, and performs the LFR. The phyA is itself heterogeneous which may explain its functional complexity. It comprises two native types, phyA′ and phyA″, the products of post-translational modification of the molecule at the N-terminus, possibly, via serine phosphorylation. This alters chromophore-apoprotein interactions resulting in the different photochemical, phenomenological, and functional properties of the two phyA pools. The phyA′ is major, water-soluble, and light-labile; the phyA″ is minor, amphiphilic, and relatively light-stable. The phyA′ mediates the VLFR whereas the water-soluble fraction of phyA″ is responsible for the HIR and LFR, the processes taking place in the nucleus. The membrane- (protein-) associated fraction of phyA” is likely to participate in the cytoplasmic photoregulation processes. The phyA pools' functions—their mode, intensity and sign—depend on plant's species, genotype and organ/tissue. The evidence of the existence of the two distinct phyA types in a plant, and their physicochemical properties and their role in the phyA functioning are discussed.
  • 1.5K
  • 17 May 2023
Topic Review
Research Trends on Islamic Finance and Fintech
Due to its devotion to Shariah principles and values, Islamic finance has attracted substantial attention as an alternative to traditional finance. With the increased use of technology in finance, Islamic finance has adapted and integrated financial technology (fintech) to provide its consumers with more efficient and accessible financial services. The rise of fintech has created new possibilities and difficulties for the Islamic finance industry, providing creative solutions to old financial issues while also raising new regulatory and ethical concerns. 
  • 1.5K
  • 15 Aug 2023
Topic Review
Role of Interleukins in Wound Healing
Interleukins (ILs) are a group of signaling molecules that play a crucial role in the immune response, inflammation, and tissue repair processes, including wound healing.
  • 1.5K
  • 11 Sep 2023
Topic Review
Healthy Building in China
Healthy buildings are a deep-level development of green buildings, which can effectively help relieve stress and improve occupants’ physical and mental health. In addition, they are is likely to play an important role in preventing the spread of respiratory infectious diseases. Therefore, healthy buildings have attracted worldwide attention. The development of healthy buildings in China is quite different from that of other countries and has its own characteristics with many factors, such as project implementation, environmental pollution, and social issues affecting healthy buildings development in China. 
  • 1.5K
  • 28 Mar 2022
Topic Review
Sustainable Agriculture
In the last few decades, a great deal has been written on the use of sustainable agriculture to improve the resilience of ecosystem services to climate change. However, no tangible and systematic evidence exists on how this agriculture would participate in alleviating impacts on vulnerable rural communities. This entry provides a narrative systematic review (SR) integrated with a bibliometric analysis and a concept network analysis to determine how, in this changing climate, sustainable agriculture can increase the resilience of agrosystems. Our search ranged from the date of the first relevant article until the end of 2018.
  • 1.5K
  • 29 Oct 2020
Topic Review
Psoriasis
Psoriasis is a common immune-mediated inflammatory skin disease characterized by well-demarcated scaly raised plaques.
  • 1.5K
  • 22 Apr 2021
Topic Review
AuNPs and Fibrous Materials
The use of nanoparticles is a multidisciplinary approach to provide UV blocking, antimicrobial, water repellent, colorant, flame retardant, sensing, and self-cleaning properties to textiles. Particularly, the antimicrobial textiles with improved functionalities find several applications, namely, in health and hygiene products, infection control, and barrier material. Depositing nanoparticles in textiles have been a promising strategy to achieve multifunctional materials. Particularly, antimicrobial properties are highly valuable due to the emergence of new pathogens and the spread of existing ones. Various techniques have been used by researchers to functionalize natural and synthetic fibers with AuNPs such as sputtering, electrostatic assembly, chemical reduction in solution, dip-coating, electroless plating, drop and dry, biosynthesis, and print pasting method.
  • 1.5K
  • 11 May 2021
Topic Review
Review Microwave Resonant Glucose Sensors
The measurement of glucose concentration finds interesting potential applications in both industry and biomedical contexts. Among the proposed solutions, the use of microwave planar resonant sensors has led to remarkable scientific activity during the last years. These sensors rely on the changes in the dielectric properties of the medium due to variations in the glucose concentration. These devices show electrical responses dependent on the surrounding dielectric properties, and therefore the changes in their response can be related to variations in the glucose content. This work shows an up-to-date review of this sensing approach after more than one decade of research and development. The attempts involved are sorted by the sensing parameter, and the computation of a common relative sensitivity to glucose is proposed as general comparison tool. The manuscript also discusses the key points of each sensor category and the possible future lines and challenges of the sensing approach.
  • 1.5K
  • 09 Aug 2021
Topic Review
Complex Wastewater Matrices
Complex wastewater matrices present a major environmental concern. Besides the biodegradable organics, they may contain a great variety of toxic chemicals, heavy metals, and other xenobiotics. The electrochemically activated persulfate process, an efficient way to generate sulfate radicals, has been widely applied to the degradation of such complex effluents with very good results.
  • 1.5K
  • 20 Aug 2021
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