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Topic Review
Advancing Health Service Delivery Through Inter-Organizational Relationships
Inter-organizational relationships are distinguishing forms of interactions linking two or more organizations to “…create a synergy that multiplies the reach and effectiveness of the partners” (Taylor and Doerfel 2005, p. 122). Inter-organizational relationships are high on the health policy agenda; however, little is still known on the approached which enhance the viability of health care organizations. Inter-organizational relationships should be carefully managed at the macro (institutional), meso (governance), and micro (management) levels to foster the design and implementation of collaborative health service delivery models ensuring patient-centredness and continuity of care.
  • 1.6K
  • 24 Jan 2022
Topic Review
Reactive Oxygen Species/Salicylic Acid in Plant Immune Response
One of the earliest hallmarks of plant immune response is production of reactive oxygen species (ROS) in different subcellular compartments, which regulate plant immunity. A suitable equilibrium, which is crucial to prevent ROS overaccumulation leading to oxidative stress, is maintained by salicylic acid (SA), a chief regulator of ROS. However, ROS not only act downstream of SA signaling, but are also proposed to be a central component of a self-amplifying loop that regulates SA signaling as well as the interaction balance between different phytohormones. The exact role of this crosstalk, the position where SA interferes with ROS signaling and ROS interferes with SA signaling and the outcome of this regulation, depend on the origin of ROS but also on the pathosystem. The precise spatiotemporal regulation of organelle-specific ROS and SA levels determine the effectiveness of pathogen arrest and is therefore crucial for a successful immune response. However, the regulatory interplay behind still remains poorly understood, as up until now, the role of organelle-specific ROS and SA in hypersensitive response (HR)-conferred resistance has mostly been studied by altering the level of a single component. In order to address these aspects, a sophisticated combination of research methods for monitoring the spatiotemporal dynamics of key players and transcriptional activity in plants is needed and will most probably consist of biosensors and precision transcriptomics. 
  • 1.6K
  • 23 Aug 2022
Topic Review
Major Challenges for Seafood Packaging
Seafood is a highly economical product worldwide. Primary modes of deterioration include autolysis, oxidation of protein and lipids, formation of biogenic amines and melanosis, and microbial deterioration. These post-harvest losses can be properly handled if the appropriate packaging technology has been applied. Therefore, it is necessary for packaging deterioration relevance to be clearly understood. 
  • 1.6K
  • 28 Sep 2022
Topic Review
Ringed Seals and Climate Change
Ringed seals are the smallest and most abundant member of the seal family that live in the Arctic and Sub-Arctic regions. The average life span of a ringed seal is 40 years, with a diet based mainly on Arctic cod and planktonic crustaceans. Typically about 5 feet (1.5 m) long, the ringed seal is known to be solitary with their main predator being polar bears. Recently, however, the biggest predator to ringed seals has been the changing temperature in the Arctic and the detrimental changes to sea ice that follow. With declines in snowpack and sea ice due to warming ocean and atmospheric temperatures, survival has become tougher for ringed seals in the Arctic and Sub-Arctic regions. Yet ringed seals are also potentially projected to thrive due to warming, considering the early extinction of their predators. Climate change is sure to change the fate of all ringed seals in the coming years for better or worse.
  • 1.6K
  • 20 Oct 2022
Topic Review
Bismuth Indium
The elements bismuth and indium have relatively low melting points when compared to other metals, and their alloy Bismuth Indium is classified as a fusible alloy. It has a melting point lower than the eutectic point of the tin lead alloy. The most common application of the alloy is as a low temperature solder, which can also contain, besides Bismuth and Indium, lead, cadmium and tin.
  • 1.6K
  • 10 Nov 2022
Biography
William Henry Chamberlin
William Henry Chamberlin Jr. (February 12, 1870 – May 9, 1921) was an American Mormon philosopher, theologian, and educator. His teachings and writings worked to reconcile Mormonism with the theory of evolution. He taught philosophy and ancient languages as well as science and math at several Latter-day Saints (LDS) institutions including Brigham Young University in the early 20th century. He
  • 1.6K
  • 25 Nov 2022
Topic Review
Thermal Conductivity Improvement of PCCs
To overcome the long-standing disadvantages of PCMs, for instance, small values of thermal conductivity, liquid leakage, separation of phase, and the problem of supercooling, advanced phase change composites (PCCs) manufactured by chemical modifications or the incorporation of functional additives are essential to overcome these disadvantages and promote the large-scale application of PCMs.
  • 1.6K
  • 29 Nov 2022
Biography
John Holdren
John Paul Holdren (Sewickley, Pennsylvania, March 1, 1944) is an American scientist. He served as the senior advisor to President Barack Obama on science and technology issues through his roles as Assistant to the President for Science and Technology, Director of the White House Office of Science and Technology Policy, and Co-Chair of the President’s Council of Advisors on Science and Technolo
  • 1.6K
  • 30 Nov 2022
Topic Review
Economic Input-Output Life Cycle Assessment in Electricity Generation
Economic Input-Output Life Cycle Assessment (EIO-LCA) is a top-down approach intertwined with the environmental satellite accounts provided by the national statistical office. Through the use of economic input-output (IO) tables and industrial sector-level environmental and energy data, the EIO-LCA analysis allows for broad impact coverage of all sectors directly and indirectly involved with electricity generation. 
  • 1.6K
  • 30 Mar 2023
Topic Review
Nutritional Value of Bee Pollen
Bee pollen (BP)’s richness in nutrients, such as proteins, vitamins, minerals, oligo-elements, and unsaturated fatty acids, is certain, along with the fact that it provides a moderate calorie intake as well as a good level of tolerance and safety, except for in the case of allergic reactions or external pollution, which remain manageable and predictable.
  • 1.6K
  • 06 Jun 2023
Topic Review
Channel Codes for Underwater Acoustic Communications
Due to the simultaneous existence of severe difficulties caused by multi-path, Doppler, and environmental noise caused by underwater acoustic channels, designing a stable and reliable underwater acoustic communication system (UWACS) is a challenging task. In addition to channel estimation and equalization, the technique of channel codes, which is capable of approaching Shannon’s capacity at a low encoding and decoding complexity, offers an efficient and reliable solution to improve the performance of the UWACS and thus draws extensive attention from the research community.
  • 1.6K
  • 21 Dec 2023
Topic Review
Quantum Rayleigh Annihilation of Entangled Photons and Quantum Local Realism
The interpretation of published experimental results intended to prove the existence of a quantum phenomenon of non-locality involving photonic entangled states did not take into consideration the existence of the quantum Rayleigh conversion of photons in dielectric media. This phenomenon leads to the existence of high levels of correlations between two independent photonic and linearly polarized quantum states generated after the entangled photons have been absorbed through the quantum Rayleigh conversion. Both pure and mixed individual states of polarization result in expressions normally associated with entangled photonic states, providing support for the view that the physical reality of quantum non-locality is highly questionable.
  • 1.6K
  • 28 Oct 2020
Topic Review
Plasmids Mediating Quinolone Resistance
Plasmid-mediated quinolone resistance (PMQR) remains one of the main mechanisms of bacterial quinolone resistance and plays an important role in the transmission of antibiotic resistance genes (ARGs). The two novel plasmids, p3M-2A and p3M-2B, which mediate quinolone resistance in Proteus vulgaris strain 3M (P3M) were identified. Of these, only p3M-2B appeared to be a qnrD-carrying plasmid. Both p3M-2A and p3M-2B could be transferred into Escherichia coli, and the latter caused a twofold change in ciprofloxacin resistance, according to the measured minimum inhibitory concentration (MIC). Plasmid curing/complementation and qRT-PCR results showed that p3M-2A can directly regulate the expression of qnrD in p3M-2B under treatment with ciprofloxacin, in which process, ORF1 was found to play an important role. Sequence alignments and phylogenetic analysis revealed the evolutionary relationships of all reported qnrD-carrying plasmids and showed that ORF1–4 in p3M-2B is the most conserved backbone for the normal function of qnrD-carrying plasmids. The identified direct repeats (DR) suggested that, from an evolutionary perspective, p3M-2B may have originated from the 2683-bp qnrD-carrying plasmid and may increase the possibility of plasmid recombination and then of qnrD transfer. To the best of our knowledge, this is the first identification of a novel qnrD-carrying plasmid isolated from a P. vulgaris strain of shrimp origin and a plasmid that plays a regulatory role in qnrD expression. This study also sheds new light on plasmid evolution and on the mechanism of horizontal transfer of ARGs encoded by plasmids.
  • 1.6K
  • 27 Oct 2020
Topic Review
Computational NMR of Carbohydrates
Nowadays, computational NMR is widely used for structural and stereochemical studies of a wide series of carbohydrates including mono-, di-, and polysaccharides together with their functional derivatives. Stereochemical analysis of carbohydrates could mostly be performed by using computational versus experimental 1H and 13C-NMR chemical shifts and spin-spin coupling constants in view of their marked stereochemical dependences providing a new guide in stereochemical structure of carbohydrates together with fundamental factors controlling molecular recognition and catalysis in biochemical systems.
  • 1.6K
  • 05 May 2021
Topic Review
Energy Performance
The energy performance of semi-transparent Building Integrated Photovoltaics (BIPV), in a variety of climatic and environmental conditions, is the subject of interest in this review.
  • 1.6K
  • 28 Jan 2022
Topic Review
Non-alcoholic Fatty Liver Disease Pathogenesis and Oxidative Stress
Non-alcoholic fatty liver disease (NAFLD) is a challenging disease caused by multiple factors, which may partly explain why it still remains an orphan of adequate therapies. It highlights the interaction between oxidative stress (OS) and disturbed lipid metabolism. Several reactive oxygen species generators, including those produced in the gastrointestinal tract, contribute to the lipotoxic hepatic (and extrahepatic) damage by fatty acids and a great variety of their biologically active metabolites in a “multiple parallel-hit model”. This leads to inflammation and fibrogenesis and contributes to NAFLD progression. The alterations of the oxidant/antioxidant balance affect also metabolism-related organelles, leading to lipid peroxidation, mitochondrial dysfunction, and endoplasmic reticulum stress. This OS-induced damage is at least partially counteracted by the physiological antioxidant response. Therefore, modulation of this defense system emerges as an interesting target to prevent NAFLD development and progression. For instance, probiotics, prebiotics, diet, and fecal microbiota transplantation represent new therapeutic approaches targeting the gut microbiota dysbiosis. The OS and its counter-regulation are under the influence of individual genetic and epigenetic factors as well.
  • 1.6K
  • 14 Feb 2022
Topic Review
Xishuangbanna Cucumber: Current Status and Future Prospects
The Xishuangbanna (XIS) cucumber is an important botanical variety, accumulating high levels of β-carotene (700 μg/100 g) in the endocarp of mature fruit compared with normal green/white flesh types (25–50 μg/100 g, fresh weight). β-carotene is an essential precursor of provitamin A synthesis required for human health, thus XIS cucumber is an appealing germplasm for vitamin A breeding programs.
  • 1.6K
  • 17 Feb 2022
Topic Review
Forest Vulnerability to Climate Change
Climate change has caused vulnerability not only to the forest ecosystem but also to forest-dependent communities. Therefore, its management is essential to increase forest ecosystem services and reduce vulnerability to climate change using an integrated approach.
  • 1.6K
  • 01 Jul 2022
Topic Review
Applications of Texturing in Injection Molding
Texturing is an engineering technology that can be used to enable surface functionalization in the plastics injection molding industry. A texture is defined as the geometrical modification of the topography by addition of surface features that are characterized by a smaller scale than the overall surface dimensions. Texturing is added to products to create novel functionalities of plastic products and tools, which can be exploited to modify interactions with other materials in contact with the surface.
  • 1.6K
  • 24 Aug 2022
Topic Review
Local Search (Internet)
Local search is the use of specialized Internet search engines that allow users to submit geographically constrained searches against a structured database of local business listings. Typical local search queries include not only information about "what" the site visitor is searching for (such as keywords, a business category, or the name of a consumer product) but also "where" information, such as a street address, city name, postal code, or geographic coordinates like latitude and longitude. Examples of local searches include "Hong Kong hotels", "Manhattan restaurants", and "Dublin car rental". Local searches exhibit explicit or implicit local intent. A search that includes a location modifier, such as "Bellevue, WA" or "14th arrondissement", is an explicit local search. A search that references a product or service that is typically consumed locally, such as "restaurant" or "nail salon", is an implicit local search. Local searches on Google Search typically return organic results prefaced with a 'local 3-pack', a list of three local results. More local results can be obtained by clicking on “more places” under the 3-pack. The list of results one obtains is also called the Local Finder. Search engines and directories are primarily supported by advertising from businesses that wish to be prominently featured when users search for specific products and services in specific locations. Google for instance, has developed local inventory ads and features ads in the local pack. Local search advertising can be highly effective because it allows ads to be targeted very precisely to the search terms and location provided by the user.
  • 1.6K
  • 29 Sep 2022
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