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Topic Review
Distributed Edge Computing in IoT-Based Smart Cities
Smart cities using the Internet of Things (IoT) can operate various IoT systems with better services that provide intelligent and efficient solutions for various aspects of urban life. With the rapidly growing number of IoT systems, the many smart city services, and their various quality of service (QoS) constraints, servers face the challenge of allocating limited resources across all Internet-based applications to achieve an efficient per-formance. The presence of a cloud in the IoT system of a smart city results in high energy con-sumption and delays in the network. Edge computing is based on a cloud computing framework where computation, storage, and network resources are moved close to the data source. The IoT framework is identical to cloud computing. The critical issue in edge computing when executing tasks generated by IoT systems is the efficient use of energy while maintaining delay limitations.
  • 1.7K
  • 21 Jul 2022
Topic Review
American Farm Bureau Federation
The American Farm Bureau Federation (AFBF), more commonly known as Farm Bureau Insurance and Farm Bureau Incorporated (FB), is a United States -based insurance company and lobbying group that represents large agricultural corporations. Headquartered in Washington, D.C., the Farm Bureau has affiliates in all 50 states and Puerto Rico.
  • 1.7K
  • 01 Nov 2022
Topic Review
Malnutrition in Children
Malnutrition in children is common globally and may result in both short and long term irreversible negative health outcomes. The World Health Organization (WHO) estimates that malnutrition accounts for 54 percent of child mortality worldwide, about 1 million children. Another estimate also by WHO states that childhood underweight is the cause for about 35% of all deaths of children under the age of five years worldwide. The main causes are unsafe water, inadequate sanitation or insufficient hygiene, factors related to society and poverty, diseases, maternal factors, gender issues and – overall – poverty. Malnutrition in this article specifically refers to undernutrition where an individual is not getting enough calories, protein, or micronutrients. (It could also refer to a condition where too much food is consumed such that the diet causes health problems).
  • 1.7K
  • 25 Nov 2022
Topic Review
Effects of Global Warming on Oceans
Effects of global warming on oceans provides information on the various effects that global warming has on oceans. Global warming can affect sea levels, coastlines, ocean acidification, ocean currents, seawater, sea surface temperatures, tides, the sea floor, weather, and trigger several changes in ocean bio-geochemistry; all of these affect the functioning of a society.
  • 1.7K
  • 29 Nov 2022
Topic Review
Actuators for Implantable Devices
The choice of actuators dictates how an implantable biomedical device moves. Specifically, the concept of implantable robots consists of the three pillars: actuators, sensors, and powering. Robotic devices that require active motion are driven by a biocompatible actuator. Depending on the actuating mechanism, different types of actuators vary remarkably in strain/stress output, frequency, power consumption, and durability. Most reviews to date focus on specific type of actuating mechanism (electric, photonic, electrothermal, etc.) for biomedical applications. With a rapidly expanding library of novel actuators, however, the granular boundaries between subcategories turns the selection of actuators a laborious task, which can be particularly time-consuming to those unfamiliar with actuation. 
  • 1.7K
  • 07 Dec 2022
Topic Review
Pharmacological Effects of Flueggea virosa Extracts
The white berry bush, officially Flueggea virosa (Roxb. ex Willd.) Royle is a medicinal plant distributed throughout tropical areas and traditionally used in Africa, India and China. Root decoctions are used to treat abdominal pain, whereas extracts from the aerial parts serve to treat liver and urinary diseases, inflammatory pathologies and diabetes, among other pathologies. Plant extracts have revealed antiparasitic, antimicrobial, antiepilepsy, antidiabetic, anticancer and analgesic effects.
  • 1.7K
  • 23 Jan 2024
Topic Review
Paper-Based Analytical Devices for Colorimetric
The so-called paper-based analytical devices (PADs) have arisen as an efficient, affordable, user-friendly, rapid, and equipment-free technology that is available to citizens. The development of PADs in areas such as clinical diagnostics, food safety and environmental monitoring, etc., as well as fabrication methods, target analytes and analytical performance, has been extensively reviewed during the last decade, with the scientific community showing great interest toward these appealing analytical approaches.
  • 1.7K
  • 06 Dec 2021
Topic Review
PledgeMusic
PledgeMusic is an online direct-to-fan music platform, launched in August 2009, that facilitates musicians reaching out to their fanbase (termed Pledgers) to pre-sell, market, and distribute music projects including recordings, music videos, and concerts. Broadly speaking it bears some similarities to such platforms as ArtistShare, Kickstarter, Indiegogo, Patreon, RocketHub and Sellaband.
  • 1.7K
  • 08 Nov 2022
Topic Review
Flavonoids in Skin Senescence Prevention
Skin aging is associated with the accumulation of senescent cells and is related to many pathological changes, including decreased protection against pathogens, increased susceptibility to irritation, delayed wound healing, and increased cancer susceptibility. Senescent cells secrete a specific set of pro-inflammatory mediators, referred to as a senescence-associated secretory phenotype (SASP), which can cause profound changes in tissue structure and function. Thus, drugs that selectively eliminate senescent cells (senolytics) or neutralize SASP (senostatics) represent an attractive therapeutic strategy for age-associated skin deterioration. There is growing evidence that plant-derived compounds (flavonoids) can slow down or even prevent aging-associated deterioration of skin appearance and function by targeting cellular pathways crucial for regulating cellular senescence and SASP. This review summarizes the senostatic and senolytic potential of flavonoids in the context of preventing skin aging.
  • 1.7K
  • 22 Sep 2021
Topic Review
Huntington’s Disease Mechanisms
Huntington’s disease (HD), despite its extrinsic simplicity—only mutation in one gene underlies the pathogenesis—has no effective treatment today. Designing an anti-HD therapy that would eliminate etiology is a topical and relevant task of biomedicine.
  • 1.7K
  • 07 Dec 2023
Topic Review
Strain Gradient Plasticity Theories (SGPT)
SGTs are featured with the introduction of one or more scale lengths in the model used to describe the medium behavior.  Among all the SGTs, those that make use of the gradient of the plastic part of the strain are called Strain Gradient Plasticity Theories (SGPT).
  • 1.7K
  • 23 Sep 2020
Topic Review
New Organizational Structures
The structure of an organization can be defined as a relatively fixed pattern of formal authority, responsibility relationships, and information flows and sources. Although the traditional forms of the organizational structure have been widely studied (Mintzberg, 1989), new organizational structures have yet to be clearly defined. 
  • 1.7K
  • 02 Feb 2021
Topic Review
Retinopathy of Prematurity
Retinopathy of prematurity (ROP) is an ocular vascular disease affecting premature infants, characterized by pathological retinal neovascularization (RNV), dilated and tortuous retinal blood vessels, and retinal or vitreous hemorrhages that may lead to retinal detachment, vision impairment and blindness.
  • 1.7K
  • 22 Sep 2021
Topic Review
Segmentectomy for Lung Cancer
A lung segmentectomy, a type of sublobar resection, preserves more pulmonary function than is lobectomy. The use of minimally invasive lung segmentectomy for early-stage lung cancer has been increasing. This procedure is associated with technical challenges because (1) it requires a thorough understanding of the complex segmental anatomy that frequently accompanies anomalies, and (2) it is difficult to confirm the location of small tumors during minimally invasive surgery, which makes it difficult to obtain adequate surgical margins. 
  • 1.7K
  • 22 Jul 2021
Topic Review
Job Shop Scheduling
Job shop scheduling is one of the most frequently used types of scheduling in manufacturing facilities. In recent years, various research has been conducted to analyze the integration and impacts of the Industry 4.0 environment on job shop scheduling.
  • 1.7K
  • 05 Aug 2021
Topic Review
Lactic Acid Bacteria against Mycotoxins
Mycotoxins (aflatoxin, ochratoxin, patulin, zearalenone, fumonisins, trichothecenes) are a large group of chemically diverse, non-protein, low-molecular secondary metabolites produced by molds. They constitute a global threat to human food and health. The generally regarded as safe (GRAS) status and long history as essential ingredients of fermented foods and probiotics make Lactic Acid Bacteria (LAB) a major biological tool against various food-related toxins. Numerous studies have shown LAB to be effective against all major mycotoxins.
  • 1.7K
  • 17 May 2022
Topic Review
Social Innovation in Rural Areas
Social innovation is gaining momentum in academia, policy and practice, as a process by which local communities generate new social relations and become more capable of addressing social needs and opportunities. This entry describes the most essential facts of social innovation processes in rural communities. 
  • 1.7K
  • 17 Jun 2022
Topic Review
Plant-Endophyte Interaction
Plants interact with diverse microbial communities and share complex relationships with each other. The intimate association between microbes and their host mutually benefit each other and provide stability against various biotic and abiotic stresses to plants. Endophytes are heterogeneous groups of microbes that live inside the host tissue without showing any apparent sign of infection.
  • 1.7K
  • 06 Sep 2022
Topic Review
Neuropilin Related Pathological Conditions
Neuropilin 1 (NRP1) represents one of the two homologous neuropilins (NRP, splice variants of neuropilin 2 are the other) found in all vertebrates. It forms a transmembrane glycoprotein distributed in many human body tissues as a (co)receptor for a variety of different ligands.
  • 1.7K
  • 08 Oct 2022
Topic Review
Strategies to Increase HDR-Dependent CRISPR-Cas9 Mediated Genome Editing
CRISPR (Clustered regularly interspaced short palindromic repeats) technology affords a simple and robust way to edit the genomes of cells, providing powerful tools for basic research and medicine. While using Cas9 to cleave a genomic site is very efficient, making a specific mutation at that site is much less so, as it depends on the endogenous DNA repair machinery. Various strategies have been developed to increase the efficiency of knock-in mutagenesis, mostly focusing on improving homology-directed repair (HDR) while reducing non-homologous end joining (NHEJ). Some approaches affect these repair mechanisms globally, while others target their modulations to the site of the Cas9-induced double-strand break (DSB). Other innovations serve to increase the specificity and the efficiency of the editing mechanisms. In addition, methods such as base editing and prime editing produce knock-in mutations without a DSB.
  • 1.7K
  • 19 Oct 2022
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